Brief Information of the Compound and Protein
Compound Name
5-[4-(1,3-Benzoxazol-2-ylamino)phenyl]-6-methylthieno-[2,3-d]pyrimidin-4-amine
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PubChem ID
CID: 6539977
SID: 16815362
Canonical SMILES
Cc1sc2ncnc(N)c2c1-c1ccc(Nc2nc3ccccc3o2)cc1
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Compound Formula C20H15N5OS
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 169.82 nM