| Compound ID |
Compound Name |
Compound Formula |
|
CP0883124
|
N-((1S,2S)-2-hydroxycyclohexyl)-1-methoxy-4-((6-(1-methyl-1H-pyrazol-4-yl)pyridin-3-yl)methyl)-2-naphthamide
Show/Hide
|
C28H30N4O3
|
1
|
| 1 |
Activity = 17 nM
|
|
|
|
CP0876096
|
4-(2,3'-bipyridin-5-ylmethyl)-N-((1S,2S)-2-hydroxycyclohexyl)-1-methoxy-2-naphthamide
Show/Hide
|
C29H29N3O3
|
1
|
| 1 |
Activity = 24 nM
|
|
|
|
CP0922019
|
5-fluoro-1-(4-(3-methyl-1H-pyrazol-1-yl)benzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C21H16FN3O3
|
1
|
| 1 |
Activity = 36 nM
|
|
|
|
CP0949383
|
5-fluoro-4-oxo-1-(4-(4-phenyl-1H-imidazol-1-yl)benzyl)-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C26H18FN3O3
|
1
|
| 1 |
Activity = 39 nM
|
|
|
|
CP0946250
|
N-((1S,2S)-2-hydroxycyclohexyl)-1-methoxy-4-((6-vinylpyridin-3-yl)methyl)-2-naphthamide
Show/Hide
|
C26H28N2O3
|
1
|
| 1 |
Activity = 74 nM
|
|
|
|
CP0861387
|
4-((6-(1H-pyrazol-1-yl)pyridin-3-yl)methyl)-N-((1S,2S)-2-hydroxycyclohexyl)-1-methoxy-2-naphthamide
Show/Hide
|
C27H28N4O3
|
1
|
| 1 |
Activity = 87 nM
|
|
|
|
CP0949374
|
1-(4-(1H-pyrrolo[2,3-b]pyridin-1-yl)benzyl)-5-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C24H16FN3O3
|
1
|
| 1 |
Activity = 90 nM
|
|
|
|
CP0928865
|
1-(4-(1H-pyrazol-1-yl)benzyl)-5-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C20H14FN3O3
|
1
|
| 1 |
Activity = 94 nM
|
|
|
|
CP0874753
|
1-(4-(1H-benzo[d]imidazol-1-yl)benzyl)-5-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C24H16FN3O3
|
1
|
| 1 |
Activity = 96 nM
|
|
|
|
CP0911221
|
1-(4-(1H-pyrazol-1-yl)benzyl)-8-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C20H14FN3O3
|
1
|
| 1 |
Activity = 96 nM
|
|
|
|
CP0940004
|
1-(4-(1H-imidazol-1-yl)benzyl)-5-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C20H14FN3O3
|
1
|
| 1 |
Activity = 110 nM
|
|
|
|
CP0882434
|
N-((1S,2S)-2-hydroxycyclohexyl)-1-methoxy-4-((6-methylpyridin-3-yl)methyl)-2-naphthamide
Show/Hide
|
C25H28N2O3
|
1
|
| 1 |
Activity = 121 nM
|
|
|
|
CP0925692
|
5-fluoro-1-(4-(4-methyl-1H-imidazol-1-yl)benzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C21H16FN3O3
|
1
|
| 1 |
Activity = 140 nM
|
|
|
|
CP0861389
|
N-((1S,2S)-2-hydroxycyclohexyl)-1-methoxy-4-((6-methoxypyridin-3-yl)methyl)-2-naphthamide
Show/Hide
|
C25H28N2O4
|
1
|
| 1 |
Activity = 140 nM
|
|
|
|
CP0919709
|
1-(4-(1H-pyrrolo[3,2-b]pyridin-1-yl)benzyl)-5-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C24H16FN3O3
|
1
|
| 1 |
Activity = 150 nM
|
|
|
|
CP0911222
|
1-(4-(1H-pyrrolo[3,2-c]pyridin-1-yl)benzyl)-5-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C24H16FN3O3
|
1
|
| 1 |
Activity = 160 nM
|
|
|
|
CP0882435
|
N-((1S,2S)-2-hydroxycyclohexyl)-1-methoxy-4-((6-(methylthio)pyridin-3-yl)methyl)-2-naphthamide
Show/Hide
|
C25H28N2O3S
|
1
|
| 1 |
Activity = 170 nM
|
|
|
|
CP0851746
|
1-(4-(1H-pyrazol-1-yl)benzyl)-5,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C20H13F2N3O3
|
1
|
| 1 |
Activity = 171 nM
|
|
|
|
CP0916388
|
1-(4-(1H-pyrrol-1-yl)benzyl)-5-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C21H15FN2O3
|
1
|
| 1 |
Activity = 181 nM
|
|
|
|
CP0876097
|
4-((6-ethylpyridin-3-yl)methyl)-N-((1S,2S)-2-hydroxycyclohexyl)-1-methoxy-2-naphthamide
Show/Hide
|
C26H30N2O3
|
1
|
| 1 |
Activity = 190 nM
|
|
|
|
CP0846967
|
5-hydroxy-1-(4-(1-isobutyl-1H-pyrazol-4-yl)benzyl)-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C24H27N3O4
|
1
|
| 1 |
Activity = 200 nM
|
|
|
|
CP0846966
|
1-(biphenyl-4-ylmethyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C23H17NO3
|
1
|
| 1 |
Activity = 212 nM
|
|
|
|
CP0929851
|
1-(4-(1H-benzo[d][1,2,3]triazol-1-yl)benzyl)-5-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C23H15FN4O3
|
1
|
| 1 |
Activity = 228 nM
|
|
|
|
CP0849985
|
1-(4-(1H-indol-1-yl)benzyl)-5-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C25H17FN2O3
|
1
|
| 1 |
Activity = 250 nM
|
|
|
|
CP0883125
|
4-((6-chloropyridin-3-yl)methyl)-N-((1S,2S)-2-hydroxycyclohexyl)-1-methoxy-2-naphthamide
Show/Hide
|
C24H25ClN2O3
|
1
|
| 1 |
Activity = 260 nM
|
|
|
|
CP0925693
|
5-fluoro-4-oxo-1-(4-(3-(trifluoromethyl)-1H-pyrazol-1-yl)benzyl)-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C21H13F4N3O3
|
1
|
| 1 |
Activity = 290 nM
|
|
|
|
CP0861388
|
4-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-N-((1S,2S)-2-hydroxycyclohexyl)-1-methoxy-2-naphthamide
Show/Hide
|
C30H34N4O3
|
1
|
| 1 |
Activity = 303 nM
|
|
|
|
CP0919496
|
5-hydroxy-1-(4-(6-methoxypyridin-3-yl)benzyl)-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C23H22N2O5
|
1
|
| 1 |
Activity = 320 nM
|
|
|
|
CP0914078
|
1-((4'-chlorobiphenyl-4-yl)methyl)-5-hydroxy-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C23H20ClNO4
|
1
|
| 1 |
Activity = 340 nM
|
|
|
|
CP0914080
|
1-((3'-chlorobiphenyl-4-yl)methyl)-5-hydroxy-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C23H20ClNO4
|
1
|
| 1 |
Activity = 340 nM
|
|
|
|
CP0859019
|
5-hydroxy-1-((3'-methoxybiphenyl-4-yl)methyl)-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C24H23NO5
|
1
|
| 1 |
Activity = 410 nM
|
|
|
|
CP0917264
|
1-((5-(3-aminophenyl)pyridin-2-yl)methyl)-5-hydroxy-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C22H21N3O4
|
1
|
| 1 |
Activity = 420 nM
|
|
|
|
CP0777219
|
1-(biphenyl-4-ylmethyl)-5-hydroxy-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C23H21NO4
|
1
|
| 1 |
Activity = 440 nM
|
|
|
|
CP0925690
|
5-fluoro-4-oxo-1-(4-(2-oxooxazolidin-3-yl)benzyl)-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C20H15FN2O5
|
1
|
| 1 |
Activity = 500 nM
|
|
|
|
CP0949382
|
5-fluoro-1-(4-(3-methyl-1H-indazol-1-yl)benzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C25H18FN3O3
|
1
|
| 1 |
Activity = 620 nM
|
|
|
|
CP0314375
|
1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C18H15NO4
|
4
|
| 1 |
Activity = 660 nM
|
|
|
| 2 |
EC50 = 845 nM
|
|
|
| 3 |
EC50 = 8317.64 nM
|
|
|
| 4 |
Kd = 54954.09 nM
|
|
|
|
CP0894161
|
1-(4-(furan-3-yl)benzyl)-5-hydroxy-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C21H19NO5
|
1
|
| 1 |
Activity = 750 nM
|
|
|
|
CP0853017
|
1-(biphenyl-4-ylmethyl)-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C23H21NO3
|
1
|
| 1 |
Activity = 751 nM
|
|
|
|
CP0874763
|
1-(biphenyl-4-ylmethyl)-4,5-dioxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C23H19NO4
|
1
|
| 1 |
Activity = 800 nM
|
|
|
|
CP0846971
|
1-(biphenyl-4-ylmethyl)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[b]pyridine-3-carboxylic acid
Show/Hide
|
C22H19NO3
|
1
|
| 1 |
Activity = 810 nM
|
|
|
|
CP0922017
|
1-((6-(1H-pyrazol-1-yl)pyridin-3-yl)methyl)-8-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C19H13FN4O3
|
1
|
| 1 |
Activity = 864 nM
|
|
|
|
CP0772513
|
5-hydroxy-1-(4-(1-methyl-1H-pyrazol-4-yl)benzyl)-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C21H21N3O4
|
1
|
| 1 |
Activity = 908 nM
|
|
|
|
CP0949384
|
5-fluoro-1-(4-(2-methyl-1H-imidazol-1-yl)benzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C21H16FN3O3
|
1
|
| 1 |
Activity = 920 nM
|
|
|
|
CP0852746
|
4-((6-chloropyridin-3-yl)methyl)-1-ethoxy-N-((1S,2S)-2-hydroxycyclohexyl)-2-naphthamide
Show/Hide
|
C25H27ClN2O3
|
1
|
| 1 |
Activity = 980 nM
|
|
|
|
CP0915475
|
1-(4-(6-(dimethylamino)pyridin-3-yl)benzyl)-5-hydroxy-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C24H25N3O4
|
1
|
| 1 |
Activity = 1095 nM
|
|
|
|
CP0846964
|
1-(biphenyl-4-ylmethyl)-5-methoxy-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C24H23NO4
|
1
|
| 1 |
Activity = 1100 nM
|
|
|
|
CP0874762
|
1-((5-(4-fluorophenyl)pyridin-2-yl)methyl)-5-hydroxy-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C22H19FN2O4
|
1
|
| 1 |
Activity = 1100 nM
|
|
|
|
CP0861391
|
1-(allyloxy)-4-((6-chloropyridin-3-yl)methyl)-N-((1S,2S)-2-hydroxycyclohexyl)-2-naphthamide
Show/Hide
|
C26H27ClN2O3
|
1
|
| 1 |
Activity = 1100 nM
|
|
|
|
CP0794378
|
1-(4-(1H-pyrazol-1-yl)benzyl)-5-hydroxy-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C20H19N3O4
|
1
|
| 1 |
Activity = 1369 nM
|
|
|
|
CP0950349
|
5-hydroxy-1-((4'-methoxybiphenyl-4-yl)methyl)-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C24H23NO5
|
1
|
| 1 |
Activity = 1386 nM
|
|
|
|
CP0917263
|
1-((2'-chlorobiphenyl-4-yl)methyl)-5-hydroxy-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C23H20ClNO4
|
1
|
| 1 |
Activity = 1400 nM
|
|
|
|
CP0874752
|
1-((5-(1H-pyrazol-1-yl)pyridin-2-yl)methyl)-8-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C19H13FN4O3
|
1
|
| 1 |
Activity = 1400 nM
|
|
|
|
CP0914055
|
1-(4-(6-aminopyridin-3-yl)benzyl)-5-hydroxy-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C22H21N3O4
|
1
|
| 1 |
Activity = 2425 nM
|
|
|
|
CP0919498
|
1-(4-(1H-imidazol-1-yl)benzyl)-5-hydroxy-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C20H19N3O4
|
1
|
| 1 |
Activity = 2500 nM
|
|
|
|
CP0922018
|
5-fluoro-4-oxo-1-(4-(2-oxopyrrolidin-1-yl)benzyl)-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C21H17FN2O4
|
1
|
| 1 |
Activity = 2500 nM
|
|
|
|
CP0874689
|
5-hydroxy-4-oxo-1-(4-(thiophen-3-yl)benzyl)-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C21H19NO4S
|
1
|
| 1 |
Activity = 2640 nM
|
|
|
|
CP0874765
|
5-fluoro-1-(4-(5-methyl-1H-pyrazol-1-yl)benzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C21H16FN3O3
|
1
|
| 1 |
Activity = 2900 nM
|
|
|
|
CP0846968
|
5-hydroxy-1-((2'-methoxybiphenyl-4-yl)methyl)-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C24H23NO5
|
1
|
| 1 |
Activity = 3100 nM
|
|
|
|
CP0908533
|
1-methoxy-4-(4-methoxybenzyl)-2-naphthoic acid
Show/Hide
|
C20H18O4
|
1
|
| 1 |
Activity = 3330 nM
|
|
|
|
CP0941598
|
N-((1S,2S)-2-hydroxycyclohexyl)-1-methoxy-4-((4-(1-methyl-1H-pyrazol-4-yl)piperazin-1-yl)methyl)-2-naphthamide
Show/Hide
|
C27H35N5O3
|
1
|
| 1 |
Activity = 3900 nM
|
|
|
|
CP0861392
|
N-((1S,2S)-2-hydroxycyclohexyl)-4-((4-(isoquinolin-3-yl)piperazin-1-yl)methyl)-1-methoxy-2-naphthamide
Show/Hide
|
C32H36N4O3
|
1
|
| 1 |
Activity = 4000 nM
|
|
|
|
CP0853018
|
1-(biphenyl-4-ylmethyl)-4,8-dioxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C23H19NO4
|
1
|
| 1 |
Activity = 4890 nM
|
|
|
|
CP0954413
|
4-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-1-methoxy-2-naphthoic acid
Show/Hide
|
C24H23N3O3
|
1
|
| 1 |
Activity = 5400 nM
|
|
|
|
CP0908532
|
4-((6-chloropyridin-3-yl)methyl)-1-ethyl-N-((1S,2S)-2-hydroxycyclohexyl)-2-naphthamide
Show/Hide
|
C25H27ClN2O2
|
1
|
| 1 |
Activity = 7400 nM
|
|
|
|
CP0846970
|
1-(biphenyl-4-ylmethyl)-8-hydroxy-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C23H21NO4
|
1
|
| 1 |
Activity = 8190 nM
|
|
|
|
CP0909768
|
4-((6-chloropyridin-3-yl)methyl)-1-hydroxy-N-((1S,2S)-2-hydroxycyclohexyl)-2-naphthamide
Show/Hide
|
C23H23ClN2O3
|
1
|
| 1 |
Activity = 9100 nM
|
|
|
|
CP0861390
|
4-((6-chloropyridin-3-yl)methyl)-2-((1S,2S)-2-hydroxycyclohexylcarbamoyl)naphthalen-1-yl acetate
Show/Hide
|
C25H25ClN2O4
|
1
|
| 1 |
Activity > 10000 nM
|
|
|
|
CP0919497
|
1-(4-(6-fluoropyridin-3-yl)benzyl)-5-hydroxy-4-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid
Show/Hide
|
C22H19FN2O4
|
1
|
| 1 |
Activity = 14790 nM
|
|
|
|
CP0925689
|
1-((6-(1H-pyrazol-1-yl)pyridazin-3-yl)methyl)-8-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Show/Hide
|
C18H12FN5O3
|
1
|
| 1 |
Activity = 24000 nM
|
|
|
|
CP0388123
|
6-fluoro-5-methyl-3-[1-(1-methyl-4-propoxycyclohexyl)piperidin-4-yl]-1H-benzimidazol-2-one
Show/Hide
|
C23H34FN3O2
|
1
|
| 1 |
EC50 = 0.3981 nM
|
|
|
|
CP0416347
|
CHEMBL1223804
Show/Hide
|
C23H34N2O2
|
1
|
| 1 |
EC50 = 0.3981 nM
|
|
|
|
CP0372671
|
6-methyl-1-[1-(1-methyl-4-propoxycyclohexyl)piperidin-4-yl]-3H-indol-2-one
Show/Hide
|
C24H36N2O2
|
1
|
| 1 |
EC50 = 0.5012 nM
|
|
|
|
CP0405990
|
2-(3-chlorophenyl)-6-fluoro-N-[[(3R,4S)-3-methylpiperidin-4-yl]methyl]benzamide
Show/Hide
|
C20H22ClFN2O
|
1
|
| 1 |
EC50 = 0.7943 nM
|
|
|
|
CP0467374
|
1-[2-(3-chlorophenyl)phenyl]-3-piperidin-4-ylpropan-1-ol
Show/Hide
|
C20H24ClNO
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0388126
|
3-[1-(4-ethoxy-1-methylcyclohexyl)piperidin-4-yl]-6-fluoro-5-methyl-1,3-benzoxazol-2-one
Show/Hide
|
C22H31FN2O3
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0372675
|
CHEMBL1223861
Show/Hide
|
C22H31FN2O3
|
1
|
| 1 |
EC50 = 1.259 nM
|
|
|
|
CP0366625
|
4-(4,5-dihydro-1,2-oxazol-3-yloxy)but-2-ynyl-trimethylazanium
Show/Hide
|
C10H17N2O2+
|
2
|
| 1 |
EC50 = 2.042 nM
|
|
|
| 2 |
Kd = 2137.96 nM
|
|
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CP0372676
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CHEMBL1223862
Show/Hide
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C22H32N2O4
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1
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| 1 |
EC50 = 2.512 nM
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CP0406096
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CHEMBL1223940
Show/Hide
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C23H34N2O4
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1
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| 1 |
EC50 = 2.512 nM
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CP0514870
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CHEMBL1223939
Show/Hide
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C23H34N2O5S
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1
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| 1 |
EC50 = 2.512 nM
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CP0400210
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2-(3-chlorophenyl)-6-fluoro-N-(1,2,3,6-tetrahydropyridin-4-ylmethyl)benzamide
Show/Hide
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C19H18ClFN2O
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1
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| 1 |
EC50 = 3.162 nM
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CP0372673
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CHEMBL1223805
Show/Hide
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C22H32N2O2
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1
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| 1 |
EC50 = 3.162 nM
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CP0374543
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3-[1-(4-ethoxy-1-methylcyclohexyl)piperidin-4-yl]-2-oxo-1,3-benzoxazole-5-carbonitrile
Show/Hide
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C22H29N3O3
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1
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| 1 |
EC50 = 3.162 nM
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CP0316264
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6-fluoro-5-methyl-3-[1-(oxan-4-yl)piperidin-4-yl]-1H-benzimidazol-2-one
Show/Hide
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C18H24FN3O2
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2
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| 1 |
EC50 = 5.012 nM
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| 2 |
EC50 = 7.943 nM
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CP0186462
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5-methyl-3-[1-(oxan-4-yl)piperidin-4-yl]-1H-benzimidazol-2-one
Show/Hide
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C18H25N3O2
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1
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| 1 |
EC50 = 5.012 nM
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CP0547319
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2-[(3R,4S)-3-hydroxyoxan-4-yl]-6-methyl-7-[[4-(1,3-thiazol-4-yl)phenyl]methyl]-3,4-dihydroisoquinolin-1-one
Show/Hide
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C25H26N2O3S
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1
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| 1 |
EC50 = 7 nM
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CP0388124
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3-[1-(4-methoxy-1-methylcyclohexyl)piperidin-4-yl]-5-methyl-1,3-benzoxazol-2-one
Show/Hide
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C21H30N2O3
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1
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| 1 |
EC50 = 7.943 nM
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CP0406277
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N-[(3R,4S)-3-hydroxyoxan-4-yl]-7-methyl-1-[[4-(1-methylpyrazol-3-yl)phenyl]methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C25H27N5O3
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1
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| 1 |
EC50 = 9 nM
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CP0534795
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N-[(3S,4S)-4-hydroxyoxan-3-yl]-1-[[4-(methylcarbamoyl)phenyl]methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C22H24N4O4
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1
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| 1 |
EC50 = 9.1 nM
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CP0528931
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1-[[2-fluoro-4-(1-methylpyrazol-4-yl)phenyl]methyl]-N-[(1S,2S)-2-hydroxycyclohexyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C25H26FN5O2
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1
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| 1 |
EC50 = 9.8 nM
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CP0400212
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2-(3-chlorophenyl)-6-fluoro-N-[[(3S,4R)-4-fluoro-3-methylpiperidin-4-yl]methyl]benzamide
Show/Hide
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C20H21ClF2N2O
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1
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| 1 |
EC50 = 10 nM
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CP0406059
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2-(5-chloro-2-fluorophenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
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C19H20ClFN2O
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1
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| 1 |
EC50 = 10 nM
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CP0374547
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3-[1-[4-(2-methoxyethoxy)-1-methylcyclohexyl]piperidin-4-yl]-2-oxo-1,3-benzoxazole-5-carbonitrile
Show/Hide
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C23H31N3O4
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1
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| 1 |
EC50 = 10 nM
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CP0534796
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N-[(3S,4S)-4-hydroxyoxan-3-yl]-1-[[4-(1-methylpyrazol-4-yl)phenyl]methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C24H25N5O3
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1
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| 1 |
EC50 = 11.1 nM
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CP0387137
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N-[(1S,2S)-2,5-dihydroxycyclohexyl]-6-methyl-2-oxo-5-[(4-pyrazol-1-ylphenyl)methyl]-1H-pyridine-3-carboxamide
Show/Hide
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C23H26N4O4
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1
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| 1 |
EC50 = 12 nM
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CP0473116
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2-(3-chloro-4-methylphenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
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C20H23ClN2O
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1
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| 1 |
EC50 = 12.59 nM
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CP0374545
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3-[1-(4-ethoxy-1-methylcyclohexyl)piperidin-4-yl]-5-methylsulfonyl-1,3-benzoxazol-2-one
Show/Hide
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C22H32N2O5S
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1
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| 1 |
EC50 = 12.59 nM
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CP0045829
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3-(1-cyclohexylpiperidin-4-yl)-1H-benzimidazol-2-one
Show/Hide
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C18H25N3O
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1
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| 1 |
EC50 = 12.59 nM
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CP0858221
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6-(1-Benzyl-7-bromo-4-oxo-1,4-dihydroquinoline-3-carboxamido)-N-(4-((4,5-dihydroisoxazol-3-yl)oxy)but-2-yn-1-yl)-N,N-dimethylhexan-1-aminium bromide
Show/Hide
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C32H38Br2N4O4
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2
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| 1 |
EC50 = 15.49 nM
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| 2 |
Kd = 74.13 nM
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CP0545496
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1-[[3-fluoro-4-(1-methylpyrazol-4-yl)phenyl]methyl]-N-[(3S,4S)-4-hydroxyoxan-3-yl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C24H24FN5O3
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1
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| 1 |
EC50 = 15.5 nM
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CP0507924
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2-(3-chlorophenyl)-6-fluoro-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
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C19H20ClFN2O
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1
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| 1 |
EC50 = 15.85 nM
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CP0547317
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2-[(3R,4S)-3-hydroxyoxan-4-yl]-6-methyl-7-[(4-pyrazol-1-ylphenyl)methyl]-3,4-dihydroisoquinolin-1-one
Show/Hide
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C25H27N3O3
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1
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| 1 |
EC50 = 18 nM
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CP0506411
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2-(3-chlorophenyl)-6-fluoro-N-[[(3R,4R)-3-methylpiperidin-4-yl]methyl]benzamide
Show/Hide
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C20H22ClFN2O
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1
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| 1 |
EC50 = 19.95 nM
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CP0416360
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2-(3-chlorophenyl)-N-[(3-methylpiperidin-4-yl)methyl]benzamide
Show/Hide
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C20H23ClN2O
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1
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| 1 |
EC50 = 19.95 nM
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CP0483863
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N-[(3R,4S)-3-hydroxyoxan-4-yl]-1,6-dimethyl-2-oxo-5-[(4-pyrazol-1-ylphenyl)methyl]pyridine-3-carboxamide
Show/Hide
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C23H26N4O4
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1
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| 1 |
EC50 = 20 nM
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CP0384741
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4-bromo-N-[(1R,2R)-6-[[N-[(4-fluorophenyl)methyl]-C-methylcarbonimidoyl]amino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
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C25H23BrFN3O2
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1
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| 1 |
EC50 = 20.9 nM
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CP0416746
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N-[(1R,2R)-6-[1-[(4-fluorophenyl)methyl-methylamino]ethylideneamino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-4-phenylbenzamide
Show/Hide
|
C32H30FN3O2
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1
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| 1 |
EC50 = 22.8 nM
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CP0541797
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2-[(3R,4S)-3-hydroxyoxan-4-yl]-6-methyl-7-[[4-(2-methyl-1,3-oxazol-4-yl)phenyl]methyl]-3,4-dihydroisoquinolin-1-one
Show/Hide
|
C26H28N2O4
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1
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| 1 |
EC50 = 23 nM
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CP0547318
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2-[(3R,4S)-3-hydroxyoxan-4-yl]-5-methyl-6-[[4-(1,3-thiazol-4-yl)phenyl]methyl]-3H-isoindol-1-one
Show/Hide
|
C24H24N2O3S
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1
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| 1 |
EC50 = 24 nM
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CP0400211
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3-chloro-6-(3-chlorophenyl)-2-fluoro-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
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C19H19Cl2FN2O
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1
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| 1 |
EC50 = 25.12 nM
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CP0502016
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2-(3-chloro-4-fluorophenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
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C19H20ClFN2O
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1
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| 1 |
EC50 = 25.12 nM
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CP0388125
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CHEMBL1223807
Show/Hide
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C21H30N2O3
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1
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| 1 |
EC50 = 25.12 nM
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CP0383721
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1-[[2-fluoro-4-(1-methylpyrazol-4-yl)phenyl]methyl]-N-[(1S,2S)-2-hydroxycyclohexyl]pyrazolo[4,3-b]pyridine-3-carboxamide
Show/Hide
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C24H25FN6O2
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1
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| 1 |
EC50 = 25.3 nM
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CP0000324
|
2-acetoxyethyl(trimethyl)ammonium;bromide
Show/Hide
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C7H16NO2+
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4
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| 1 |
EC50 = 25.9 nM
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| 2 |
EC50 = 371.54 nM
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| 3 |
Kd = 17378.01 nM
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| 4 |
Ki = 13489.63 nM
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CP0104319
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2-[(3R,4S)-3-hydroxyoxan-4-yl]-6-methyl-7-[[4-(1,3-oxazol-4-yl)phenyl]methyl]-3,4-dihydroisoquinolin-1-one
Show/Hide
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C25H26N2O4
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1
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| 1 |
EC50 = 26 nM
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CP0405261
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2-[(3R,4S)-3-hydroxyoxan-4-yl]-5-methyl-6-[[4-(1-methylpyrazol-4-yl)phenyl]methyl]-3H-isoindol-1-one
Show/Hide
|
C25H27N3O3
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1
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| 1 |
EC50 = 27 nM
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CP0544785
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1-[[2-fluoro-4-(1-methylpyrazol-4-yl)phenyl]methyl]-N-[(3R,4S)-3-hydroxyoxan-4-yl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C24H24FN5O3
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1
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| 1 |
EC50 = 28.5 nM
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CP0485182
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N-[(1S,2S)-2-hydroxycyclohexyl]-1,6-dimethyl-2-oxo-5-[(4-pyrazol-1-ylphenyl)methyl]pyridine-3-carboxamide
Show/Hide
|
C24H28N4O3
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1
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| 1 |
EC50 = 29 nM
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CP0528933
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1-[[2-fluoro-4-(1-methylpyrazol-4-yl)phenyl]methyl]-N-[(3S,4S)-4-hydroxyoxan-3-yl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
|
C24H24FN5O3
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1
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| 1 |
EC50 = 30.3 nM
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CP0384746
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4-chloro-N-[(1R,2R)-6-[1-[(4-fluorophenyl)methyl-methylamino]ethylideneamino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
|
C26H25ClFN3O2
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1
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| 1 |
EC50 = 31 nM
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CP0471047
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2-(2,5-dichlorophenyl)-6-fluoro-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
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C19H19Cl2FN2O
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1
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| 1 |
EC50 = 31.62 nM
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CP0887420
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N-(4-(1-Benzyl-7-chloro-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxamido)butyl)-4-((4,5-dihydroisoxazol-3-yl)oxy)-N,N-dimethylbut-2-yn-1-aminium bromide
Show/Hide
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C30H33BrClFN4O4
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2
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| 1 |
EC50 = 32.36 nM
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| 2 |
Kd = 72.44 nM
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CP0540629
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N-[(1S,2S)-2-hydroxycyclohexyl]-1-[[4-(1-oxidopyrazol-1-ium-1-yl)phenyl]methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C24H25N5O3
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1
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| 1 |
EC50 = 34 nM
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CP0450608
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N-[(3S,4S)-4-hydroxyoxan-3-yl]-1-[[6-(1-methylpyrazol-4-yl)pyridin-3-yl]methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
|
C23H24N6O3
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1
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| 1 |
EC50 = 34.8 nM
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CP0403240
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N-[(1R,2R)-6-[1-[(4-fluorophenyl)methyl-methylamino]ethylideneamino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C27H25F4N3O2
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1
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| 1 |
EC50 = 36 nM
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CP0558616
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2-[(3R,4S)-3-hydroxyoxan-4-yl]-5-methyl-6-[(4-pyrazol-1-ylphenyl)methyl]-3H-isoindol-1-one
Show/Hide
|
C24H25N3O3
|
1
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| 1 |
EC50 = 36 nM
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CP0483861
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4-[[4-(5-carbamoylpyridin-3-yl)phenyl]methyl]-N-[(1S,2S)-2-hydroxycyclohexyl]pyrrolo[1,2-b]pyridazine-2-carboxamide
Show/Hide
|
C27H27N5O3
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1
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| 1 |
EC50 = 36 nM
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CP0483862
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N-[(1S,2S)-2-hydroxycyclohexyl]-1,6-dimethyl-5-[[4-(1,3-oxazol-4-yl)phenyl]methyl]-2-oxopyridine-3-carboxamide
Show/Hide
|
C24H27N3O4
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1
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| 1 |
EC50 = 38 nM
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CP0406800
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2-(3-chlorophenyl)-N-[[(3R,4S)-3-ethylpiperidin-4-yl]methyl]-6-fluorobenzamide
Show/Hide
|
C21H24ClFN2O
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1
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| 1 |
EC50 = 39.81 nM
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CP0487780
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2-(2,5-dichlorophenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
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C19H20Cl2N2O
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1
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| 1 |
EC50 = 39.81 nM
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CP0532743
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N-[(1S,2S)-2-hydroxycyclohexyl]-6-(hydroxymethyl)-1-methyl-2-oxo-5-[(4-pyrazol-1-ylphenyl)methyl]pyridine-3-carboxamide
Show/Hide
|
C24H28N4O4
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1
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| 1 |
EC50 = 40 nM
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CP0569763
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N-[(1S,2S)-2-hydroxycyclohexyl]-4-[[4-(6-methylpyridin-2-yl)phenyl]methyl]pyrrolo[1,2-b]pyridazine-2-carboxamide
Show/Hide
|
C27H28N4O2
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1
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| 1 |
EC50 = 41 nM
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CP0468085
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2-[(3R,4S)-3-hydroxyoxan-4-yl]-5-methyl-6-[[4-(4-methylimidazol-1-yl)phenyl]methyl]-3H-isoindol-1-one
Show/Hide
|
C25H27N3O3
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1
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| 1 |
EC50 = 45 nM
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CP0405616
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2-[(3R,4S)-3-hydroxyoxan-4-yl]-5-methyl-6-[[4-(1,3-oxazol-4-yl)phenyl]methyl]-3H-isoindol-1-one
Show/Hide
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C24H24N2O4
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3
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| 1 |
EC50 = 47 nM
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| 2 |
EC50 >= 5000 nM
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| 3 |
Ki = 16 nM
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CP0383722
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1-[[2-fluoro-4-(1-methylpyrazol-4-yl)phenyl]methyl]-N-[(3S,4S)-3-hydroxy-3-methyloxan-4-yl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
|
C25H26FN5O3
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1
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| 1 |
EC50 = 47.9 nM
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CP0128076
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8-Chloro-11-piperazin-1-yl-5H-dibenzo[b,e][1,4]diazepine
Show/Hide
|
C17H17ClN4
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1
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| 1 |
EC50 = 48 nM
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CP0384745
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4-bromo-N-[(1R,2R)-6-[[N-[(3-fluorophenyl)methyl]-C-methylcarbonimidoyl]amino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
|
C25H23BrFN3O2
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1
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| 1 |
EC50 = 48.4 nM
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CP0413709
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N-[(1R,2R)-6-[1-[(4-fluorophenyl)methyl-methylamino]ethylideneamino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-4-methylbenzamide
Show/Hide
|
C27H28FN3O2
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1
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| 1 |
EC50 = 49.5 nM
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CP0547321
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2-[(3R,4S)-3-hydroxyoxan-4-yl]-5-methyl-6-[[4-(2-methyl-1,3-oxazol-4-yl)phenyl]methyl]-3H-isoindol-1-one
Show/Hide
|
C25H26N2O4
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1
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| 1 |
EC50 = 50 nM
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CP0438844
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2-(3-chlorophenyl)-5-fluoro-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C19H20ClFN2O
|
1
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| 1 |
EC50 = 50.12 nM
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CP0507926
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2-[2-(3-chlorophenyl)phenyl]-N-methyl-N-piperidin-4-ylacetamide
Show/Hide
|
C20H23ClN2O
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1
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| 1 |
EC50 = 50.12 nM
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CP0386493
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2-(3,4-dichlorophenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
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C19H20Cl2N2O
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1
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| 1 |
EC50 = 50.12 nM
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CP0513110
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4-bromo-N-[(1R,2R)-6-[[N-(4-fluorophenyl)-C-methylcarbonimidoyl]amino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
|
C24H21BrFN3O2
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1
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| 1 |
EC50 = 51 nM
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CP0105825
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N-[(3R,4S)-3-hydroxyoxan-4-yl]-1-[[4-(1-methylpyrazol-3-yl)phenyl]methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
|
C24H25N5O3
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3
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| 1 |
EC50 = 55 nM
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| 2 |
EC50 > 1000 nM
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| 3 |
Ki = 40 nM
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CP0847964
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N-(4-(1-Benzyl-8-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxamido)butyl)-4-((4,5-dihydroisoxazol-3-yl)oxy)-N,N-dimethylbut-2-yn-1-aminium bromide
Show/Hide
|
C30H34BrFN4O4
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2
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| 1 |
EC50 = 57.54 nM
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| 2 |
Kd = 151.36 nM
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CP0908591
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6-(1-Benzyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxamido)-N-(4-((4,5-dihydroisoxazol-3-yl)oxy)but-2-yn-1-yl)-N,N-dimethylhexan-1-aminium bromide
Show/Hide
|
C32H38BrFN4O4
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2
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| 1 |
EC50 = 58.88 nM
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| 2 |
Kd = 151.36 nM
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CP0189836
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N-[(3R,4S)-3-hydroxyoxan-4-yl]-5-methyl-4-[[4-(1,3-thiazol-4-yl)phenyl]methyl]pyridine-2-carboxamide
Show/Hide
|
C22H23N3O3S
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8
|
| 1 |
EC50 = 60 nM
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| 2 |
EC50 = 365 nM
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| 3 |
EC50 = 447 nM
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| 4 |
EC50 = 3900 nM
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| 5 |
EC50 >= 3900 nM
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| 6 |
EC50 > 4000 nM
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| 7 |
EC50 >= 9200 nM
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| 8 |
Ki = 19 nM
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CP0450617
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N-[(3S,4R)-3-hydroxyoxan-4-yl]-1-methyl-4-[[4-(1-methylpyrazol-3-yl)phenyl]methyl]pyrrolo[2,3-b]pyridine-6-carboxamide
Show/Hide
|
C25H27N5O3
|
2
|
| 1 |
EC50 = 60 nM
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| 2 |
EC50 = 60.26 nM
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CP0384673
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1-[[6-[8-[(2S)-2-ethyl-3-oxo-1-thia-4,8-diazaspiro[4.5]decan-4-yl]octoxy]naphthalen-2-yl]methyl]-8-fluoro-4-oxoquinoline-3-carboxylic acid
Show/Hide
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C38H44FN3O5S
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2
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| 1 |
EC50 = 60.26 nM
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| 2 |
Kd = 165.96 nM
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CP0455621
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N-[(3R,4S)-3-hydroxyoxan-4-yl]-1-[(4-pyrazol-1-ylphenyl)methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C23H23N5O3
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1
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| 1 |
EC50 = 63 nM
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CP0124201
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3-[(1S,2S)-2-hydroxycyclohexyl]-6-[(6-methylpyridin-3-yl)methyl]benzo[h]quinazolin-4-one
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C25H25N3O2
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3
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| 1 |
EC50 = 63 nM
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| 2 |
EC50 > 2000 nM
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| 3 |
Ki = 8 nM
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CP0476715
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N-[(1S,2S)-2,4-dihydroxycyclohexyl]-1,6-dimethyl-2-oxo-5-[(4-pyrazol-1-ylphenyl)methyl]pyridine-3-carboxamide
Show/Hide
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C24H28N4O4
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1
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| 1 |
EC50 = 63 nM
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CP0405989
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2-(3-chlorophenyl)-6-fluoro-N-[(4-fluoropiperidin-4-yl)methyl]benzamide
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C19H19ClF2N2O
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1
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| 1 |
EC50 = 63.1 nM
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CP0406794
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2-chloro-6-(3-chlorophenyl)-N-(piperidin-4-ylmethyl)benzamide
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C19H20Cl2N2O
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1
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| 1 |
EC50 = 63.1 nM
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CP0417830
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4-[2-[2-(3-chlorophenyl)phenyl]sulfonylethyl]piperidine
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C19H22ClNO2S
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1
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| 1 |
EC50 = 63.1 nM
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CP0386486
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2-(3-chlorophenyl)-N-(piperidin-4-ylmethyl)benzamide
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C19H21ClN2O
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1
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| 1 |
EC50 = 63.1 nM
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CP0045827
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3-[1-(oxan-4-yl)piperidin-4-yl]-1H-benzimidazol-2-one
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C17H23N3O2
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1
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| 1 |
EC50 = 63.1 nM
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CP0946281
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N-(4-(1-Benzyl-7-bromo-4-oxo-1,4-dihydroquinoline-3-carboxamido)butyl)-4-((4,5-dihydroisoxazol-3-yl)oxy)-N,N-dimethylbut-2-yn-1-aminium bromide
Show/Hide
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C30H34Br2N4O4
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2
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| 1 |
EC50 = 63.1 nM
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| 2 |
Kd = 141.25 nM
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CP0049755
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(R)-1-Aza-bicyclo[2.2.2]oct-3-yl-[(Z)-methoxyimino]-acetonitrile
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C10H15N3O
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2
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| 1 |
EC50 = 63.6 nM
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| 2 |
Ki = 229.09 nM
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CP0395111
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N-[(3R,4S)-3-hydroxyoxan-4-yl]-1-[[4-(1H-pyrazol-5-yl)phenyl]methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C23H23N5O3
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2
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| 1 |
EC50 = 65 nM
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| 2 |
EC50 = 77 nM
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CP0371787
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5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine; oxalic acid
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C14H23N3OS
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9
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| 1 |
EC50 = 67.3 nM
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| 2 |
IC50 = 18.2 nM
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| 3 |
IC50 = 28.84 nM
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| 4 |
IC50 = 81.28 nM
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| 5 |
IC50 = 954.99 nM
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| 6 |
IC50 = 2398.83 nM
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| 7 |
IC50 = 4897.79 nM
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| 8 |
Ki = 7.943 nM
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| 9 |
Ki = 42 nM
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CP0573832
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2-[(3R,4S)-3-hydroxyoxan-4-yl]-6-[(4-imidazol-1-ylphenyl)methyl]-5-methyl-3H-isoindol-1-one
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C24H25N3O3
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1
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| 1 |
EC50 = 68 nM
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CP0538728
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N-[(3R,4S)-3-hydroxyoxan-4-yl]-4-[[4-(4-hydroxypyrazol-1-yl)phenyl]methyl]-5-methylpyridine-2-carboxamide
Show/Hide
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C22H24N4O4
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1
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| 1 |
EC50 = 70 nM
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CP0464241
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N-[(3S,4S)-4-hydroxyoxan-3-yl]-1-[(1-methylindazol-5-yl)methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C22H23N5O3
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1
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| 1 |
EC50 = 71.5 nM
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CP0551770
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N-[(1R,2R)-2-hydroxycyclohexyl]-4-[(4-pyridin-3-ylphenyl)methyl]pyrrolo[1,2-b]pyridazine-2-carboxamide
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C26H26N4O2
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1
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| 1 |
EC50 = 75 nM
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CP0452978
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4-bromo-N-[(1R,2R)-2-hydroxy-6-[(1-methylpiperidin-2-ylidene)amino]-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
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C22H24BrN3O2
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1
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| 1 |
EC50 = 80 nM
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CP0553350
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N-[(1S,2S)-2-hydroxycyclohexyl]-4-[[4-(1-methylpyrazol-4-yl)phenyl]methyl]pyrrolo[1,2-b]pyridazine-2-carboxamide
Show/Hide
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C25H27N5O2
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1
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| 1 |
EC50 = 80 nM
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CP0438191
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4-bromo-N-[(1R,2R)-6-[1-[2-(4-fluorophenyl)ethyl-methylamino]ethylideneamino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
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C27H27BrFN3O2
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1
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| 1 |
EC50 = 80.9 nM
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CP0444579
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4-bromo-N-[(1R,2R)-6-[[N-[(2-fluorophenyl)methyl]-C-methylcarbonimidoyl]amino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]benzamide
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C25H23BrFN3O2
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1
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| 1 |
EC50 = 87 nM
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CP0573519
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N-[(1S,2S)-2-hydroxycyclohexyl]-1-[[4-(1-methylpyrazol-3-yl)phenyl]methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C25H27N5O2
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1
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| 1 |
EC50 = 89 nM
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CP0383279
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N-[(3S,4R)-3-hydroxyoxan-4-yl]-1-methyl-4-[[4-(1,3-thiazol-2-yl)phenyl]methyl]pyrrolo[2,3-b]pyridine-6-carboxamide
Show/Hide
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C24H24N4O3S
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2
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| 1 |
EC50 = 89.13 nM
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| 2 |
EC50 = 90 nM
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CP0568432
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N-[(1S,2S)-2-hydroxycyclohexyl]-5-methyl-4-[(4-pyrazol-1-ylphenyl)methyl]pyridine-2-carboxamide
Show/Hide
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C23H26N4O2
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1
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| 1 |
EC50 = 92 nM
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CP0444697
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N-[(1R,2R)-2-hydroxycyclohexyl]-4-[[4-(6-methylpyridin-2-yl)phenyl]methyl]pyrrolo[1,2-b]pyridazine-2-carboxamide
Show/Hide
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C27H28N4O2
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1
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| 1 |
EC50 = 96 nM
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CP0538727
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5-(hydroxymethyl)-N-[(3R,4S)-3-hydroxyoxan-4-yl]-1-[[4-(1-methylpyrazol-3-yl)phenyl]methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C25H27N5O4
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1
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| 1 |
EC50 = 99 nM
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CP0405977
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4-chloro-2-(3-chlorophenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
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C19H20Cl2N2O
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1
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| 1 |
EC50 = 100 nM
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CP0411252
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5-chloro-2-(3-chlorophenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
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C19H20Cl2N2O
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1
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| 1 |
EC50 = 100 nM
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CP0461963
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N-[(1S,2S)-2-hydroxycyclohexyl]-1-[(4-pyrazol-1-ylphenyl)methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C24H25N5O2
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2
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| 1 |
EC50 = 101 nM
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| 2 |
EC50 = 106 nM
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CP0568330
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N-[(1S,2S)-2-hydroxycyclohexyl]-1,6-dimethyl-5-[[4-(1-methylpyrazol-3-yl)phenyl]methyl]-2-oxopyridine-3-carboxamide
Show/Hide
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C25H30N4O3
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1
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| 1 |
EC50 = 102 nM
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CP0536785
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4-bromo-N-[(1R,2R)-2-hydroxy-6-[[N-(4-methoxyphenyl)-C-methylcarbonimidoyl]amino]-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
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C25H24BrN3O3
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1
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| 1 |
EC50 = 105 nM
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CP0444698
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N-[(1R,2R)-2-hydroxycyclohexyl]-4-[[4-(6-methoxypyridin-3-yl)phenyl]methyl]pyrrolo[1,2-b]pyridazine-2-carboxamide
Show/Hide
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C27H28N4O3
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1
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| 1 |
EC50 = 108 nM
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CP0566224
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N-[(3R,4S)-3-hydroxyoxan-4-yl]-5-methyl-4-[(4-pyrazol-1-ylphenyl)methyl]pyridine-2-carboxamide
Show/Hide
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C22H24N4O3
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1
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| 1 |
EC50 = 109 nM
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CP0473448
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N-[2-(dimethylamino)-2-oxoethyl]-1-[(4-pyrazol-1-ylphenyl)methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C22H22N6O2
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1
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| 1 |
EC50 = 112 nM
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CP0566223
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2-fluoro-N-[(3R,4S)-3-hydroxyoxan-4-yl]-4-methyl-5-[(4-pyrazol-1-ylphenyl)methyl]benzamide
Show/Hide
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C23H24FN3O3
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1
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| 1 |
EC50 = 115 nM
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CP0438190
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4-bromo-N-[(1R,2R)-6-[1-(4-fluoro-N-methylanilino)ethylideneamino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
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C25H23BrFN3O2
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1
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| 1 |
EC50 = 118 nM
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CP0412649
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N-[(1R,2R)-2-hydroxycyclohexyl]-1-methyl-4-[[6-(1-methylpyrazol-3-yl)pyridin-3-yl]methyl]pyrrolo[2,3-b]pyridine-6-carboxamide
Show/Hide
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C25H28N6O2
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2
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| 1 |
EC50 = 120 nM
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| 2 |
EC50 = 123.03 nM
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CP0558144
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N-[(1R,2R)-2-hydroxycyclohexyl]-4-[(4-pyridin-4-ylphenyl)methyl]pyrrolo[1,2-b]pyridazine-2-carboxamide
Show/Hide
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C26H26N4O2
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1
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| 1 |
EC50 = 133 nM
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CP0568328
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N-[(3R,4S)-3-hydroxyoxan-4-yl]-5-methyl-4-[[4-(1,3-oxazol-4-yl)phenyl]methyl]pyridine-2-carboxamide
Show/Hide
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C22H23N3O4
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1
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| 1 |
EC50 = 144 nM
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CP0444696
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4-[[4-(5-cyanopyridin-3-yl)phenyl]methyl]-N-[(1S,2S)-2-hydroxycyclohexyl]pyrrolo[1,2-b]pyridazine-2-carboxamide
Show/Hide
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C27H25N5O2
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1
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| 1 |
EC50 = 146 nM
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CP0549588
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4-[[4-(5-fluoropyridin-2-yl)phenyl]methyl]-N-[(1R,2R)-2-hydroxycyclohexyl]pyrrolo[1,2-b]pyridazine-2-carboxamide
Show/Hide
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C26H25FN4O2
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1
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| 1 |
EC50 = 149 nM
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CP0429187
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4-bromo-N-[(1R,2R)-6-[1-[(4-fluorophenyl)methyl-methylamino]ethylideneamino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
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C26H25BrFN3O2
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1
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| 1 |
EC50 = 154 nM
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CP0405979
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2-(3-chlorophenyl)-4-methyl-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
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C20H23ClN2O
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1
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| 1 |
EC50 = 158.49 nM
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CP0405985
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2-[2-(3-chlorophenyl)phenyl]-N-piperidin-4-ylacetamide
Show/Hide
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C19H21ClN2O
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1
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| 1 |
EC50 = 158.49 nM
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CP0405988
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2-(3-chlorophenyl)-6-fluoro-N-[[(3S,4R)-3-fluoropiperidin-4-yl]methyl]benzamide
Show/Hide
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C19H19ClF2N2O
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1
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| 1 |
EC50 = 158.49 nM
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CP0493268
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3-chloro-6-(3-chlorophenyl)-2-fluoro-N-[(3-methyl-1,2,3,6-tetrahydropyridin-4-yl)methyl]benzamide
Show/Hide
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C20H19Cl2FN2O
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1
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| 1 |
EC50 = 158.49 nM
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CP0493270
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3-chloro-6-(3-chlorophenyl)-2-fluoro-N-[(5-fluoro-1,2,3,6-tetrahydropyridin-4-yl)methyl]benzamide
Show/Hide
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C19H16Cl2F2N2O
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1
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| 1 |
EC50 = 158.49 nM
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CP0501900
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2-(5-chloro-2-methylphenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
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C20H23ClN2O
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1
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| 1 |
EC50 = 158.49 nM
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CP0517714
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N-[(3R,4S)-2,3-dihydroxyoxan-4-yl]-5-methyl-4-[[4-(1,3-thiazol-4-yl)phenyl]methyl]pyridine-2-carboxamide
Show/Hide
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C22H23N3O4S
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1
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| 1 |
EC50 = 162 nM
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CP0406276
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N-[(1S,2S)-2-hydroxycyclohexyl]-1-[(4-pyrazol-1-ylphenyl)methyl]indole-3-carboxamide
Show/Hide
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C25H26N4O2
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1
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| 1 |
EC50 = 163 nM
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CP0384808
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N-[(1R,2R)-6-[1-[(4-fluorophenyl)methyl-methylamino]ethylideneamino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-4-methoxybenzamide
Show/Hide
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C27H28FN3O3
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1
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| 1 |
EC50 = 166 nM
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CP0487483
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N-[(1S,2S)-2-hydroxycyclohexyl]-1,6-dimethyl-2-oxo-5-[[4-(1,3-thiazol-4-yl)phenyl]methyl]pyridine-3-carboxamide
Show/Hide
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C24H27N3O3S
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1
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| 1 |
EC50 = 166 nM
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CP0420551
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N-[[(2S)-oxolan-2-yl]methyl]-1-[(4-pyrazol-1-ylphenyl)methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C23H23N5O2
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1
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| 1 |
EC50 = 175 nM
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CP0476628
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N-[(1S,2S)-2,4-dihydroxycyclohexyl]-6-(hydroxymethyl)-1-methyl-2-oxo-5-[(4-pyrazol-1-ylphenyl)methyl]pyridine-3-carboxamide
Show/Hide
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C24H28N4O5
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1
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| 1 |
EC50 = 177 nM
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CP0850300
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6-(1-Benzyl-8-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxamido)-N-(4-((4,5-dihydroisoxazol-3-yl)oxy)but-2-yn-1-yl)-N,N-dimethylhexan-1-aminium bromide
Show/Hide
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C32H38BrFN4O4
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2
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| 1 |
EC50 = 177.83 nM
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| 2 |
Kd = 489.78 nM
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CP0412638
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N-[(1R,2R)-2-hydroxycyclohexyl]-1-methyl-4-[[4-(1-methylpyrazol-3-yl)phenyl]methyl]pyrrolo[2,3-b]pyridine-6-carboxamide
Show/Hide
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C26H29N5O2
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2
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| 1 |
EC50 = 180 nM
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| 2 |
EC50 = 181.97 nM
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CP0421623
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4-[(4-bromophenyl)methyl]-N-(oxolan-2-ylmethyl)pyrrolo[1,2-b]pyridazine-2-carboxamide
Show/Hide
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C20H20BrN3O2
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1
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| 1 |
EC50 = 181 nM
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CP0444694
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4-[[4-(1-methylpyrazol-4-yl)phenyl]methyl]-N-(oxan-4-yl)pyrrolo[1,2-b]pyridazine-2-carboxamide
Show/Hide
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C24H25N5O2
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1
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| 1 |
EC50 = 182 nM
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CP0448547
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4-bromo-N-[(1R,2R)-6-[[N-[2-(4-fluorophenyl)ethyl]-C-methylcarbonimidoyl]amino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
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C26H25BrFN3O2
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1
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| 1 |
EC50 = 183 nM
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CP0567265
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5-formyl-N-[(3R,4S)-3-hydroxyoxan-4-yl]-1-[[4-(1-methylpyrazol-3-yl)phenyl]methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C25H25N5O4
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1
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| 1 |
EC50 = 184 nM
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CP0455617
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N-[(1S,2S)-2-hydroxycyclohexyl]-1-(quinolin-6-ylmethyl)pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C24H24N4O2
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1
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| 1 |
EC50 = 185 nM
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CP0384744
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4-bromo-N-[(1R,2R)-2-hydroxy-6-[[N-[(3-methoxyphenyl)methyl]-C-methylcarbonimidoyl]amino]-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
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C26H26BrN3O3
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1
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| 1 |
EC50 = 198 nM
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CP0374546
|
CHEMBL1223938
Show/Hide
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C23H34N2O5S
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1
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| 1 |
EC50 = 199.53 nM
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CP0574397
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N-[(3R,4S)-3-hydroxyoxan-4-yl]-4-methyl-3-[(4-pyrazol-1-ylphenyl)methyl]benzamide
Show/Hide
|
C23H25N3O3
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1
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| 1 |
EC50 = 208 nM
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CP0461964
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N-[(3R,4S)-3-hydroxyoxan-4-yl]-6-methyl-1-[[4-(1-methylpyrazol-3-yl)phenyl]methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
|
C25H27N5O3
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1
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| 1 |
EC50 = 211 nM
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CP0486619
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N-[(1S,2S)-2-hydroxycyclohexyl]-1-[(4-pyrazol-1-ylphenyl)methyl]pyrazolo[4,3-b]pyridine-3-carboxamide
Show/Hide
|
C23H24N6O2
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1
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| 1 |
EC50 = 215 nM
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CP0444695
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4-[[4-(2-chloropyridin-4-yl)phenyl]methyl]-N-[(1S,2S)-2-hydroxycyclohexyl]pyrrolo[1,2-b]pyridazine-2-carboxamide
Show/Hide
|
C26H25ClN4O2
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1
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| 1 |
EC50 = 224 nM
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CP0500356
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5-[[2,6-difluoro-4-(2-methylindazol-5-yl)phenyl]methyl]-4H-thieno[2,3-c]pyrrol-6-one
Show/Hide
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C21H15F2N3OS
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1
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| 1 |
EC50 = 246 nM
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CP0552226
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N-[4-(hydroxymethyl)cyclohexyl]-1-[(4-pyrazol-1-ylphenyl)methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
|
C25H27N5O2
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1
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| 1 |
EC50 = 248 nM
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CP0400206
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2-(4-chloro-1,3-thiazol-2-yl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
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C16H18ClN3OS
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1
|
| 1 |
EC50 = 251.19 nM
|
|
|
|
CP0509256
|
N-(1-azabicyclo[2.2.2]octan-4-ylmethyl)-2-(4-chloro-1,3-thiazol-2-yl)benzamide
Show/Hide
|
C18H20ClN3OS
|
1
|
| 1 |
EC50 = 251.19 nM
|
|
|
|
CP0420552
|
N-[(3R,4S)-3-hydroxyoxan-4-yl]-5-methyl-1-[[4-(1-methylpyrazol-3-yl)phenyl]methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
|
C25H27N5O3
|
2
|
| 1 |
EC50 = 255 nM
|
|
|
| 2 |
EC50 = 293 nM
|
|
|
|
CP0455622
|
N-(1-methylpyrazol-3-yl)-1-[(4-pyrazol-1-ylphenyl)methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
|
C22H19N7O
|
1
|
| 1 |
EC50 = 258 nM
|
|
|
|
CP0455619
|
N-[(1S,2S)-2-hydroxycyclohexyl]-1-[[4-(4-pyridin-4-ylpyrazol-1-yl)phenyl]methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
|
C29H28N6O2
|
1
|
| 1 |
EC50 = 273 nM
|
|
|
|
CP0950197
|
6-(1-Benzyl-7-chloro-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxamido)-N-(4-((4,5-dihydroisoxazol-3-yl)oxy)but-2-yn-1-yl)-N,N-dimethylhexan-1-aminium bromide
Show/Hide
|
C32H37BrClFN4O4
|
2
|
| 1 |
EC50 = 302 nM
|
|
|
| 2 |
Kd = 851.14 nM
|
|
|
|
CP0533787
|
8-fluoro-3-methyl-6-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
Show/Hide
|
C20H20FN3
|
1
|
| 1 |
EC50 = 310 nM
|
|
|
|
CP0412637
|
1-methyl-4-[[6-(1-methylpyrazol-4-yl)pyridin-3-yl]methyl]-N-(oxan-4-yl)pyrrolo[2,3-b]pyridine-6-carboxamide
Show/Hide
|
C24H26N6O2
|
2
|
| 1 |
EC50 = 320 nM
|
|
|
| 2 |
EC50 = 323.59 nM
|
|
|
|
CP0416842
|
5-(hydroxymethyl)-N-[(3R,4S)-3-hydroxyoxan-4-yl]-4-[(4-pyrazol-1-ylphenyl)methyl]pyridine-2-carboxamide
Show/Hide
|
C22H24N4O4
|
1
|
| 1 |
EC50 = 338 nM
|
|
|
|
CP0421547
|
4-[[4-(1-methylpyrazol-4-yl)phenyl]methyl]-N-(oxolan-2-ylmethyl)pyrrolo[1,2-b]pyridazine-2-carboxamide
Show/Hide
|
C24H25N5O2
|
1
|
| 1 |
EC50 = 343 nM
|
|
|
|
CP0315086
|
3-chloro-6-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
Show/Hide
|
C19H18ClN3
|
1
|
| 1 |
EC50 = 350 nM
|
|
|
|
CP0549252
|
N-[(1S,2S)-2-hydroxycyclohexyl]-1-[(4-pyrimidin-5-ylphenyl)methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
|
C25H25N5O2
|
1
|
| 1 |
EC50 = 371 nM
|
|
|
|
CP0384742
|
4-fluoro-N-[(1R,2R)-6-[1-[(4-fluorophenyl)methyl-methylamino]ethylideneamino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
|
C26H25F2N3O2
|
1
|
| 1 |
EC50 = 392 nM
|
|
|
|
CP0567541
|
N-[(3R,4S)-3-hydroxyoxan-4-yl]-6-methyl-5-[(4-pyrazol-1-ylphenyl)methyl]pyridine-3-carboxamide
Show/Hide
|
C22H24N4O3
|
1
|
| 1 |
EC50 = 392 nM
|
|
|
|
CP0400208
|
N-[[2-(3-chlorophenyl)phenyl]methyl]-N-(piperidin-4-ylmethyl)acetamide
Show/Hide
|
C21H25ClN2O
|
1
|
| 1 |
EC50 = 398.11 nM
|
|
|
|
CP0085573
|
3-[1-[3-(4-fluorophenoxy)propyl]piperidin-4-yl]-1H-benzimidazol-2-one
Show/Hide
|
C21H24FN3O2
|
1
|
| 1 |
EC50 = 398.11 nM
|
|
|
|
CP0553332
|
N-(2-hydroxy-2-methylpropyl)-4-[(4-pyridin-4-ylphenyl)methyl]pyrrolo[1,2-b]pyridazine-2-carboxamide
Show/Hide
|
C24H24N4O2
|
1
|
| 1 |
EC50 = 405 nM
|
|
|
|
CP0422605
|
4-bromo-N-[(1R,2R)-2-hydroxy-6-[[N-[2-(4-methoxyphenyl)ethyl]-C-methylcarbonimidoyl]amino]-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
|
C27H28BrN3O3
|
1
|
| 1 |
EC50 = 426 nM
|
|
|
|
CP0486603
|
1-[(4-cyanophenyl)methyl]-N-[(1S,2S)-2-hydroxycyclohexyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
|
C22H22N4O2
|
1
|
| 1 |
EC50 = 478 nM
|
|
|
|
CP0473449
|
N-[(1-hydroxycyclobutyl)methyl]-1-[(4-pyrazol-1-ylphenyl)methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
|
C23H23N5O2
|
1
|
| 1 |
EC50 = 500 nM
|
|
|
|
CP0400209
|
N-[[2-(3-chlorophenyl)phenyl]methyl]piperidine-4-carboxamide
Show/Hide
|
C19H21ClN2O
|
1
|
| 1 |
EC50 = 501.19 nM
|
|
|
|
CP0405987
|
5-[2-(2,5-dichlorophenyl)-6-fluorophenyl]-3-piperidin-4-yl-1,2,4-oxadiazole
Show/Hide
|
C19H16Cl2FN3O
|
1
|
| 1 |
EC50 = 501.19 nM
|
|
|
|
CP0548267
|
N-[(3R,4S)-2,3-dihydroxyoxan-4-yl]-5-methyl-4-[(4-pyrazol-1-ylphenyl)methyl]pyridine-2-carboxamide
Show/Hide
|
C22H24N4O4
|
1
|
| 1 |
EC50 = 511 nM
|
|
|
|
CP0378965
|
3-(1-octylpiperidin-4-yl)-1H-benzimidazol-2-one
Show/Hide
|
C20H31N3O
|
1
|
| 1 |
EC50 = 537.03 nM
|
|
|
|
CP0468470
|
4-bromo-N-[(1R,2R)-2-hydroxy-6-[[N-[(2-methoxyphenyl)methyl]-C-methylcarbonimidoyl]amino]-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
|
C26H26BrN3O3
|
1
|
| 1 |
EC50 = 572 nM
|
|
|
|
CP0458070
|
1-methyl-4-[[4-(1-methylpyrazol-3-yl)phenyl]methyl]-N-(oxan-4-yl)pyrrolo[2,3-b]pyridine-6-carboxamide
Show/Hide
|
C25H27N5O2
|
2
|
| 1 |
EC50 = 660 nM
|
|
|
| 2 |
EC50 = 660.69 nM
|
|
|
|
CP0500364
|
5-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]-1-(2-pyrrolidin-1-ylethyl)-4H-pyrrolo[3,4-c]pyrazol-6-one
Show/Hide
|
C26H26F2N6O
|
1
|
| 1 |
EC50 = 739 nM
|
|
|
|
CP0386483
|
2-(4-chloro-1,3-thiazol-2-yl)-N-[(2,2,6,6-tetramethylpiperidin-4-yl)methyl]benzamide
Show/Hide
|
C20H26ClN3OS
|
1
|
| 1 |
EC50 = 794.33 nM
|
|
|
|
CP0384743
|
Talsaclidine
Show/Hide
|
C10H15NO
|
1
|
| 1 |
EC50 = 820 nM
|
|
|
|
CP0055373
|
1-(2-fluoro-4-(1-methyl-1H-pyrazol-4-yl)benzyl)indoline-2,3-dione
Show/Hide
|
C19H14FN3O2
|
1
|
| 1 |
EC50 = 830 nM
|
|
|
|
CP0089021
|
(+)-pilocarpine
Show/Hide
|
C11H16N2O2
|
3
|
| 1 |
EC50 = 831.76 nM
|
|
|
| 2 |
Kd = 2691.53 nM
|
|
|
| 3 |
Ki = 6606.93 nM
|
|
|
|
CP0416774
|
4-bromo-N-[(1R,2R)-2-hydroxy-6-[[N-[(4-methoxyphenyl)methyl]-C-methylcarbonimidoyl]amino]-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
|
C26H26BrN3O3
|
1
|
| 1 |
EC50 = 837 nM
|
|
|
|
CP0440200
|
1-(2,6-difluoro-4-(1-methyl-1H-pyrazol-4-yl)benzyl)indoline-2,3-dione
Show/Hide
|
C19H13F2N3O2
|
1
|
| 1 |
EC50 = 860 nM
|
|
|
|
CP0378045
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-prop-2-ynyl-oxime
Show/Hide
|
C9H12N2O
|
3
|
| 1 |
EC50 = 890 nM
|
|
|
| 2 |
IC50 = 4890 nM
|
|
|
| 3 |
IC50 = 9510 nM
|
|
|
|
CP0558946
|
5-[[2,6-difluoro-4-(2-methylindazol-5-yl)phenyl]methyl]-6H-furo[2,3-c]pyrrol-4-one
Show/Hide
|
C21H15F2N3O2
|
1
|
| 1 |
EC50 = 992 nM
|
|
|
|
CP0405983
|
4-[(E)-3-[2-(3-chlorophenyl)phenyl]prop-2-enyl]piperidine
Show/Hide
|
C20H22ClN
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0406795
|
2-(3-chlorophenyl)-5-methyl-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0504333
|
2-(3-chloro-2-fluorophenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C19H20ClFN2O
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0551946
|
5-[[2,6-difluoro-4-(2-methylindazol-5-yl)phenyl]methyl]-6H-thieno[2,3-c]pyrrol-4-one
Show/Hide
|
C21H15F2N3OS
|
1
|
| 1 |
EC50 = 1020 nM
|
|
|
|
CP0476834
|
1-(2,6-difluoro-4-(1-methyl-1H-pyrazol-4-yl)benzyl)-7-fluoroindoline-2,3-dione
Show/Hide
|
C19H12F3N3O2
|
1
|
| 1 |
EC50 = 1100 nM
|
|
|
|
CP0500365
|
5-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]-1-(oxolan-2-ylmethyl)-4H-pyrrolo[3,4-c]pyrazol-6-one
Show/Hide
|
C25H23F2N5O2
|
1
|
| 1 |
EC50 = 1120 nM
|
|
|
|
CP0447441
|
4,7-difluoro-1-(2-fluoro-4-(1-methyl-1H-pyrazol-4-yl)benzyl)indoline-2,3-dione
Show/Hide
|
C19H12F3N3O2
|
1
|
| 1 |
EC50 = 1200 nM
|
|
|
|
CP0168609
|
ethyl 4-[(3R)-3-[(2-methylbenzoyl)amino]piperidin-1-yl]piperidine-1-carboxylate
Show/Hide
|
C21H31N3O3
|
1
|
| 1 |
EC50 = 1300 nM
|
|
|
|
CP0536077
|
N-[(1S,2S)-2-hydroxycyclohexyl]-1-[(4-pyrazol-1-ylphenyl)methyl]-3,4-dihydro-2H-quinoline-3-carboxamide
Show/Hide
|
C26H30N4O2
|
1
|
| 1 |
EC50 = 1400 nM
|
|
|
|
CP0548511
|
5-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]-1-(2-hydroxyethyl)-4H-pyrrolo[3,4-c]pyrazol-6-one
Show/Hide
|
C22H19F2N5O2
|
1
|
| 1 |
EC50 = 1510 nM
|
|
|
|
CP0405986
|
N-[[2-(3-chlorophenyl)-6-fluorophenyl]methyl]-N-(piperidin-4-ylmethyl)methanesulfonamide
Show/Hide
|
C20H24ClFN2O2S
|
1
|
| 1 |
EC50 = 1584.89 nM
|
|
|
|
CP0504335
|
2-(3-chloro-5-methylphenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
EC50 = 1584.89 nM
|
|
|
|
CP0390382
|
4-[(2-fluoro-4-pyrazol-1-ylphenyl)methyl]-N-[(1S,2S)-2-hydroxycyclohexyl]-2,3-dihydro-1,4-benzoxazine-2-carboxamide
Show/Hide
|
C25H27FN4O3
|
1
|
| 1 |
EC50 = 1600 nM
|
|
|
|
CP0562169
|
5-[[2,6-difluoro-4-(2-methylindazol-5-yl)phenyl]methyl]-1-(oxolan-2-ylmethyl)-4H-pyrrolo[3,4-c]pyrazol-6-one
Show/Hide
|
C25H23F2N5O2
|
1
|
| 1 |
EC50 = 1660 nM
|
|
|
|
CP0566225
|
N-[(1S,2S)-2-hydroxycyclohexyl]-5-[[4-[(3R)-3-methoxypyrrolidin-1-yl]phenyl]methyl]-1,6-dimethyl-2-oxopyridine-3-carboxamide
Show/Hide
|
C26H35N3O4
|
1
|
| 1 |
EC50 = 1686 nM
|
|
|
|
CP0395017
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-but-2-ynyl-oxime
Show/Hide
|
C10H14N2O
|
2
|
| 1 |
EC50 = 1900 nM
|
|
|
| 2 |
IC50 = 5810 nM
|
|
|
|
CP0123721
|
6-[[2-fluoro-4-(1-methylpyrazol-4-yl)phenyl]methyl]-7H-pyrrolo[3,4-b]pyridin-5-one
Show/Hide
|
C18H15FN4O
|
1
|
| 1 |
EC50 = 1900 nM
|
|
|
|
CP0500355
|
5-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]-6H-thieno[2,3-c]pyrrol-4-one
Show/Hide
|
C21H15F2N3OS
|
1
|
| 1 |
EC50 = 1920 nM
|
|
|
|
CP0557965
|
5-[[2-fluoro-4-(2-methylindazol-5-yl)phenyl]methyl]-4H-pyrrolo[3,4-d][1,3]thiazol-6-one
Show/Hide
|
C20H15FN4OS
|
1
|
| 1 |
EC50 = 2000 nM
|
|
|
|
CP0485530
|
N-[(1S,2S)-2-hydroxycyclohexyl]-4-[(4-pyrrol-1-ylphenyl)methyl]-2,3-dihydro-1,4-benzoxazine-2-carboxamide
Show/Hide
|
C26H29N3O3
|
1
|
| 1 |
EC50 = 2100 nM
|
|
|
|
CP0551456
|
5-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]-4H-thieno[2,3-c]pyrrol-6-one
Show/Hide
|
C21H15F2N3OS
|
1
|
| 1 |
EC50 = 2164 nM
|
|
|
|
CP0385850
|
1-(4-(1-methyl-1H-pyrazol-4-yl)benzyl)indoline-2,3-dione
Show/Hide
|
C19H15N3O2
|
1
|
| 1 |
EC50 = 2300 nM
|
|
|
|
CP0447440
|
7-fluoro-1-(2-fluoro-4-(1-methyl-1H-pyrazol-4-yl)benzyl)indoline-2,3-dione
Show/Hide
|
C19H13F2N3O2
|
1
|
| 1 |
EC50 = 2300 nM
|
|
|
|
CP0392295
|
4-[2-(o-toluoylamino)ethylamino]piperidine-1-carboxylic acid ethyl ester;hydrochloride
Show/Hide
|
C18H27N3O3
|
1
|
| 1 |
EC50 = 2300 nM
|
|
|
|
CP0500359
|
5-[[2-fluoro-4-(2-methylindazol-5-yl)phenyl]methyl]-6H-thieno[2,3-c]pyrrol-4-one
Show/Hide
|
C21H16FN3OS
|
1
|
| 1 |
EC50 = 2780 nM
|
|
|
|
CP0488969
|
6-chloro-N-[(1S,2S)-2-hydroxycyclohexyl]-4-[(4-pyrazol-1-ylphenyl)methyl]-2,3-dihydro-1,4-benzoxazine-2-carboxamide
Show/Hide
|
C25H27ClN4O3
|
1
|
| 1 |
EC50 = 2800 nM
|
|
|
|
CP0548510
|
5-[[2,6-difluoro-4-(3-methylbenzimidazol-5-yl)phenyl]methyl]-6H-thieno[2,3-c]pyrrol-4-one
Show/Hide
|
C21H15F2N3OS
|
1
|
| 1 |
EC50 = 2870 nM
|
|
|
|
CP0558947
|
5-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]-1-(2-pyrrolidin-1-ylethyl)-4H-pyrrolo[3,4-b]pyrrol-6-one
Show/Hide
|
C27H27F2N5O
|
1
|
| 1 |
EC50 = 2920 nM
|
|
|
|
CP0406797
|
2-(3-chlorophenyl)-N-(2-piperidin-4-ylethyl)benzamide
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
EC50 = 3162.28 nM
|
|
|
|
CP0558601
|
5-[[4-(1,3-dimethylpyrazol-4-yl)-2,6-difluorophenyl]methyl]-1-(oxolan-2-ylmethyl)-4H-pyrrolo[3,4-c]pyrazol-6-one
Show/Hide
|
C22H23F2N5O2
|
1
|
| 1 |
EC50 = 3220 nM
|
|
|
|
CP0469351
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-(3-phenyl-prop-2-ynyl)-oxime
Show/Hide
|
C15H16N2O
|
2
|
| 1 |
EC50 = 3300 nM
|
|
|
| 2 |
IC50 = 5420 nM
|
|
|
|
CP0773921
|
SID50106034
Show/Hide
|
C14H18Cl2N2O2
|
3
|
| 1 |
EC50 = 3500 nM
|
|
|
| 2 |
IC50 = 4000 nM
|
|
|
| 3 |
Ki = 1949.84 nM
|
|
|
|
CP0551947
|
5-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]-2-(oxolan-2-ylmethyl)-4H-pyrrolo[3,4-c]pyrazol-6-one
Show/Hide
|
C25H23F2N5O2
|
1
|
| 1 |
EC50 = 3540 nM
|
|
|
|
CP0548512
|
5-[[2,6-difluoro-4-(2-methylpyridin-4-yl)phenyl]methyl]-1-(oxolan-2-ylmethyl)-4H-pyrrolo[3,4-c]pyrazol-6-one
Show/Hide
|
C23H22F2N4O2
|
1
|
| 1 |
EC50 = 3580 nM
|
|
|
|
CP0500363
|
5-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]-1-(2-methoxyethyl)-4H-pyrrolo[3,4-c]pyrazol-6-one
Show/Hide
|
C23H21F2N5O2
|
1
|
| 1 |
EC50 = 3930 nM
|
|
|
|
CP0558948
|
5-[[2-fluoro-4-(2-methylindazol-4-yl)phenyl]methyl]-6H-thieno[2,3-c]pyrrol-4-one
Show/Hide
|
C21H16FN3OS
|
1
|
| 1 |
EC50 = 3970 nM
|
|
|
|
CP0550592
|
N-[(1S,2S)-2-hydroxycyclohexyl]-1-[(4-pyrazol-1-ylphenyl)methyl]indazole-3-carboxamide
Show/Hide
|
C24H25N5O2
|
1
|
| 1 |
EC50 = 4500 nM
|
|
|
|
CP0460048
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-hexa-2,5-diynyl-oxime
Show/Hide
|
C12H14N2O
|
3
|
| 1 |
EC50 = 4700 nM
|
|
|
| 2 |
IC50 = 8830 nM
|
|
|
| 3 |
IC50 = 10010 nM
|
|
|
|
CP0189250
|
3-chloro-8-fluoro-6-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
Show/Hide
|
C19H17ClFN3
|
1
|
| 1 |
EC50 = 4700 nM
|
|
|
|
CP0558945
|
5-[[2-fluoro-4-(1-methylpyrazol-4-yl)phenyl]methyl]-4H-thieno[2,3-c]pyrrol-6-one
Show/Hide
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C17H14FN3OS
|
1
|
| 1 |
EC50 = 4900 nM
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CP0493259
|
2-(3-chlorophenyl)-3-fluoro-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C19H20ClFN2O
|
1
|
| 1 |
EC50 = 5011.87 nM
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CP0394561
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-hepta-2,5-diynyl-oxime
Show/Hide
|
C13H16N2O
|
2
|
| 1 |
EC50 = 5050 nM
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| 2 |
IC50 = 5680 nM
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CP0377278
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-nona-2,5,8-triynyl-oxime
Show/Hide
|
C15H16N2O
|
2
|
| 1 |
EC50 = 5100 nM
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| 2 |
IC50 = 2030 nM
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CP0567551
|
5-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]-2-(2-pyrrolidin-1-ylethyl)-4H-pyrrolo[3,4-c]pyrazol-6-one
Show/Hide
|
C26H26F2N6O
|
1
|
| 1 |
EC50 = 5180 nM
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CP0191257
|
3-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]pyrido[3,4-d]pyrimidin-4-one
Show/Hide
|
C22H15F2N5O
|
1
|
| 1 |
EC50 = 5300 nM
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CP0240069
|
N-ethyl-1-(1H-indazol-5-ylsulfonyl)-N-[[2-(trifluoromethyl)phenyl]methyl]piperidine-4-carboxamide
Show/Hide
|
C23H25F3N4O3S
|
1
|
| 1 |
EC50 = 5400 nM
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|
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CP0558600
|
5-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]-1-(3-hydroxypropyl)-4H-pyrrolo[3,4-b]pyrrol-6-one
Show/Hide
|
C24H22F2N4O2
|
1
|
| 1 |
EC50 = 5580 nM
|
|
|
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CP0635477
|
(2-Carbamoyloxy-ethyl)-trimethyl-ammonium chloride
Show/Hide
|
C6H15ClN2O2
|
6
|
| 1 |
EC50 = 5690 nM
|
|
|
| 2 |
IC50 = 4090 nM
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| 3 |
IC50 = 10000 nM
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| 4 |
Ki = 170 nM
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| 5 |
Ki = 12022.64 nM
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| 6 |
Ki = 38018.94 nM
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CP0438364
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-pent-2-ynyl-oxime
Show/Hide
|
C11H16N2O
|
2
|
| 1 |
EC50 = 5900 nM
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| 2 |
IC50 = 4900 nM
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CP0113928
|
1-(4-bromobenzyl)indoline-2,3-dione
Show/Hide
|
C15H10BrNO2
|
1
|
| 1 |
EC50 = 6100 nM
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CP0500360
|
5-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]-1-(oxolan-2-ylmethyl)-4H-pyrrolo[3,4-b]pyrrol-6-one
Show/Hide
|
C26H24F2N4O2
|
1
|
| 1 |
EC50 = 6450 nM
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CP0471424
|
5-[[2,6-difluoro-4-(2-methylindazol-7-yl)phenyl]methyl]-1-(oxolan-2-ylmethyl)-4H-pyrrolo[3,4-c]pyrazol-6-one
Show/Hide
|
C25H23F2N5O2
|
1
|
| 1 |
EC50 = 6890 nM
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|
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CP0390378
|
N-[(1S,2S)-2-hydroxycyclohexyl]-2-methyl-4-[(4-pyrazol-1-ylphenyl)methyl]-3H-1,4-benzoxazine-2-carboxamide
Show/Hide
|
C26H30N4O3
|
1
|
| 1 |
EC50 = 7300 nM
|
|
|
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CP0463368
|
N-[2-(3-chlorophenyl)phenyl]-2-piperidin-4-ylacetamide
Show/Hide
|
C19H21ClN2O
|
1
|
| 1 |
EC50 = 7943.28 nM
|
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|
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CP0500358
|
5-[(2,6-difluoro-4-quinolin-6-ylphenyl)methyl]-4H-pyrrolo[3,4-d][1,3]thiazol-6-one
Show/Hide
|
C21H13F2N3OS
|
1
|
| 1 |
EC50 = 8000 nM
|
|
|
|
CP0405978
|
2-(3-chlorophenyl)-3-methyl-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0405980
|
2-(3-chlorophenyl)-6-methyl-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0405981
|
3-(3-chlorophenyl)-N-(piperidin-4-ylmethyl)pyridine-4-carboxamide
Show/Hide
|
C18H20ClN3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0405982
|
2-(3-chlorophenyl)-N-(piperidin-4-ylmethyl)pyridine-3-carboxamide
Show/Hide
|
C18H20ClN3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0405984
|
4-[2-[2-(3-chlorophenyl)phenoxy]ethyl]piperidine
Show/Hide
|
C19H22ClNO
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0406793
|
3-chloro-2-(3-chlorophenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C19H20Cl2N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0406796
|
3-(3-chlorophenyl)-N-(piperidin-4-ylmethyl)thiophene-2-carboxamide
Show/Hide
|
C17H19ClN2OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0411254
|
3-[2-(3-chlorophenyl)-6-fluorophenyl]-5-piperidin-4-yl-1,2,4-oxadiazole
Show/Hide
|
C19H17ClFN3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0438842
|
2-(3-chlorophenyl)-4-fluoro-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C19H20ClFN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0463369
|
piperidin-4-ylmethyl 2-(3-chlorophenyl)benzoate
Show/Hide
|
C19H20ClNO2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0467373
|
3-(3-chlorophenyl)-N-(piperidin-4-ylmethyl)pyridine-2-carboxamide
Show/Hide
|
C18H20ClN3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0493263
|
4-(3-chlorophenyl)-N-(piperidin-4-ylmethyl)pyridine-3-carboxamide
Show/Hide
|
C18H20ClN3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0493265
|
N-acetyl-N-[2-(4-chlorophenyl)phenyl]-2-piperidin-4-ylacetamide
Show/Hide
|
C21H23ClN2O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0496059
|
N-[[2-(3-chlorophenyl)phenyl]methyl]-N-methylpiperidine-4-carboxamide
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0506410
|
2-(3-chlorophenyl)-N-methyl-N-(piperidin-4-ylmethyl)benzenesulfonamide
Show/Hide
|
C19H23ClN2O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0507925
|
4-(3-chlorophenyl)-1-methyl-N-(piperidin-4-ylmethyl)pyrazole-3-carboxamide
Show/Hide
|
C17H21ClN4O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0509633
|
4-[[2-(3-chlorophenyl)phenyl]methoxymethyl]piperidine
Show/Hide
|
C19H22ClNO
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0514532
|
2-(3-chlorophenyl)-N-(piperidin-4-ylmethyl)benzenesulfonamide
Show/Hide
|
C18H21ClN2O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0514550
|
N-[2-(3-chlorophenyl)phenyl]-N-methyl-2-piperidin-4-ylacetamide
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0522064
|
1-[2-(3-chlorophenyl)phenyl]-3-piperidin-4-ylpropan-1-one
Show/Hide
|
C20H22ClNO
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0522065
|
N-[[2-(3-chlorophenyl)phenyl]methyl]-1-piperidin-4-ylmethanamine
Show/Hide
|
C19H23ClN2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0522066
|
3-[2-(3-chlorophenyl)-6-fluorophenyl]-5-(piperidin-4-ylmethyl)-1,2,4-oxadiazole
Show/Hide
|
C20H19ClFN3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0386492
|
2-(3-chloro-2-methylphenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0400651
|
2-(4-chloro-1,3-thiazol-2-yl)-N-(oxan-4-ylmethyl)benzamide
Show/Hide
|
C16H17ClN2O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0400652
|
2-(3-acetamidophenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C21H25N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0400653
|
2-(2,3-dichlorophenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C19H20Cl2N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0416353
|
N-(piperidin-4-ylmethyl)-2-[4-(trifluoromethyl)phenyl]benzamide
Show/Hide
|
C20H21F3N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0416356
|
2-(3-chloro-5-fluorophenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C19H20ClFN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0416358
|
2-(3-chlorophenyl)-N-(1-piperidin-4-ylethyl)benzamide
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0416359
|
N-(1-azabicyclo[3.3.1]nonan-4-ylmethyl)-2-(3-chlorophenyl)benzamide
Show/Hide
|
C22H25ClN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0417971
|
N-(1-azabicyclo[2.2.2]octan-4-ylmethyl)-2-(3-chlorophenyl)benzamide
Show/Hide
|
C21H23ClN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0438956
|
2-(4-chloro-1,3-thiazol-2-yl)-N-(pyrrolidin-2-ylmethyl)benzamide
Show/Hide
|
C15H16ClN3OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0438959
|
2-(4-chloro-1,3-thiazol-2-yl)-N-piperidin-4-ylbenzamide
Show/Hide
|
C15H16ClN3OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0438960
|
N-(azepan-3-yl)-2-(4-chloro-1,3-thiazol-2-yl)benzamide
Show/Hide
|
C16H18ClN3OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0438961
|
3-[2-(piperidin-4-ylmethylcarbamoyl)phenyl]benzoic acid
Show/Hide
|
C20H22N2O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0438962
|
2-[3-(methoxymethyl)phenyl]-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C21H26N2O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0473090
|
2-(4-chloro-1,3-thiazol-2-yl)-N-(pyridin-4-ylmethyl)benzamide
Show/Hide
|
C16H12ClN3OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0473091
|
2-(3-methylphenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0473092
|
2-(4-methoxyphenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C20H24N2O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0473093
|
2-(3-phenylphenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C25H26N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0473094
|
2-pyridin-3-yl-N-(pyridin-4-ylmethyl)benzamide
Show/Hide
|
C18H15N3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0487824
|
2-(4-chloro-1,3-thiazol-2-yl)-N-(pyrrolidin-3-ylmethyl)benzamide
Show/Hide
|
C15H16ClN3OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0487825
|
2-naphthalen-1-yl-N-(pyridin-4-ylmethyl)benzamide
Show/Hide
|
C23H18N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0487826
|
2-(3-chlorophenyl)-N-[(4-methylpiperidin-4-yl)methyl]benzamide
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0491005
|
2-(2-methoxyphenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C20H24N2O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0491006
|
2-(3-chlorophenyl)-N-[(2-methylpiperidin-4-yl)methyl]benzamide
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0491007
|
N-(1-azabicyclo[2.2.1]heptan-4-ylmethyl)-2-(3-chlorophenyl)benzamide
Show/Hide
|
C20H21ClN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0496153
|
2-(3-chlorophenyl)-N-methyl-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0501897
|
2-(4-chloro-1,3-thiazol-2-yl)-N-(piperidin-3-ylmethyl)benzamide
Show/Hide
|
C16H18ClN3OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0501901
|
2-(3-chlorophenyl)-N-[(1-methylpiperidin-4-yl)methyl]benzamide
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0501902
|
5-chloro-2-(3-chlorophenyl)-N-[(3,3-dimethylpiperidin-4-yl)methyl]benzamide
Show/Hide
|
C21H24Cl2N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0502015
|
2-(3-carbamoylphenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C20H23N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0504329
|
2-(3-methylsulfonylphenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C20H24N2O3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0504330
|
2-pyridin-4-yl-N-(pyridin-4-ylmethyl)benzamide
Show/Hide
|
C18H15N3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0504331
|
2-naphthalen-2-yl-N-(pyridin-4-ylmethyl)benzamide
Show/Hide
|
C23H18N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0504332
|
2-(5-chlorothiophen-2-yl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C17H19ClN2OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0504334
|
2-(3,5-dichlorophenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C19H20Cl2N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0505759
|
2-[3-(dimethylcarbamoyl)phenyl]-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C22H27N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0505760
|
N-(piperidin-4-ylmethyl)-2-(3-sulfamoylphenyl)benzamide
Show/Hide
|
C19H23N3O3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0507856
|
2-(4-chloro-1,3-thiazol-2-yl)-N-(morpholin-2-ylmethyl)benzamide
Show/Hide
|
C15H16ClN3O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0507857
|
2-(3-fluorophenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C19H21FN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0507858
|
2-(4-fluorophenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C19H21FN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0507859
|
2-(3-acetylphenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C21H24N2O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0507860
|
N-(pyridin-4-ylmethyl)-2-thiophen-2-ylbenzamide
Show/Hide
|
C17H14N2OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0509257
|
N-(pyridin-4-ylmethyl)-2-thiophen-3-ylbenzamide
Show/Hide
|
C17H14N2OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0509713
|
2-(4-chloro-1,3-thiazol-2-yl)-N-pyrrolidin-3-ylbenzamide
Show/Hide
|
C14H14ClN3OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0509714
|
2-(2-chlorophenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C19H21ClN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0509715
|
N-(pyridin-4-ylmethyl)-2-(1,3-thiazol-2-yl)benzamide
Show/Hide
|
C16H13N3OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0516404
|
2-(furan-2-yl)-N-(pyridin-4-ylmethyl)benzamide
Show/Hide
|
C17H14N2O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0516407
|
N-[(4-aminocyclohexyl)methyl]-2-(3-chlorophenyl)benzamide
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0522713
|
2-(4-chloro-1,3-thiazol-2-yl)-N-piperidin-3-ylbenzamide
Show/Hide
|
C15H16ClN3OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0522714
|
2-(4-methylphenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0522715
|
2-[3-(dimethylamino)phenyl]-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C21H27N3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0522716
|
N-(piperidin-4-ylmethyl)-2-[3-(trifluoromethoxy)phenyl]benzamide
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C20H21F3N2O2
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1
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| 1 |
EC50 > 10000 nM
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CP0523810
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2-(3-methoxyphenyl)-N-(piperidin-4-ylmethyl)benzamide
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C20H24N2O2
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1
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| 1 |
EC50 > 10000 nM
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CP0523811
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N-(piperidin-4-ylmethyl)-2-[3-(trifluoromethyl)phenyl]benzamide
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C20H21F3N2O
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1
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| 1 |
EC50 > 10000 nM
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CP0523812
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2-(3-cyanophenyl)-N-(piperidin-4-ylmethyl)benzamide
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C20H21N3O
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1
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| 1 |
EC50 > 10000 nM
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CP0533347
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N-[[(1R,5S)-8-azabicyclo[3.2.1]octan-3-yl]methyl]-2-(3-chlorophenyl)benzamide
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C21H23ClN2O
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1
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| 1 |
EC50 > 10000 nM
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CP0398357
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6-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]-2,3-dihydroimidazo[1,2-c]pyrimidin-5-one
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C21H17F2N5O
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1
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| 1 |
EC50 > 10000 nM
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CP0420724
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3-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]quinazolin-4-one
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C23H16F2N4O
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1
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| 1 |
EC50 > 10000 nM
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CP0462508
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6-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]-7,8-dihydro-1,6-naphthyridin-5-one
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C23H18F2N4O
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1
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| 1 |
EC50 > 10000 nM
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CP0462511
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1-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]quinoxalin-2-one
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C23H16F2N4O
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1
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| 1 |
EC50 > 10000 nM
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CP0531456
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5-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]-4H-pyrrolo[3,4-d][1,3]oxazol-6-one
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C20H14F2N4O2
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1
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| 1 |
EC50 > 10000 nM
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CP0534060
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5-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]-3-methyl-2,6-dihydropyrrolo[3,4-c]pyrrol-4-one
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C22H18F2N4O
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1
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| 1 |
EC50 > 10000 nM
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CP0558599
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5-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]-6H-pyrrolo[3,4-d][1,3]oxazol-4-one
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C20H14F2N4O2
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1
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| 1 |
EC50 > 10000 nM
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CP0567550
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5-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]-1,6-dihydropyrrolo[3,4-d]imidazol-4-one
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C20H15F2N5O
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1
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| 1 |
EC50 > 10000 nM
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CP0025667
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2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone
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C18H19ClN4
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
Ki = 6.31 nM
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CP0040250
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2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol
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C21H25N3O2S
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
Ki = 398.11 nM
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CP0315083
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3-chloro-6-[(6S)-1,6-dimethyl-3,6-dihydro-2H-pyridin-4-yl]-8-ethyl-11H-benzo[b][1,4]benzodiazepine
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C22H24ClN3
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1
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| 1 |
EC50 > 10000 nM
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CP0362629
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6-[(6S)-1,6-dimethyl-3,6-dihydro-2H-pyridin-4-yl]-8-fluoro-3-methyl-11H-benzo[b][1,4]benzodiazepine
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C21H22FN3
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1
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| 1 |
EC50 > 10000 nM
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CP0450960
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8-fluoro-3-methyl-6-(1,2,3,6-tetrahydropyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
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C19H18FN3
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1
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| 1 |
EC50 > 10000 nM
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CP0450964
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8-ethyl-3-methyl-6-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
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C22H25N3
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1
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| 1 |
EC50 > 10000 nM
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CP0533788
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3-chloro-6-(1-ethyl-3,6-dihydro-2H-pyridin-4-yl)-8-fluoro-11H-benzo[b][1,4]benzodiazepine
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C20H19ClFN3
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1
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| 1 |
EC50 > 10000 nM
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CP0533789
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8-chloro-3-fluoro-6-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
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C19H17ClFN3
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1
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| 1 |
EC50 > 10000 nM
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CP0551894
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3-chloro-8-fluoro-6-(1,2,3,6-tetrahydropyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
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C18H15ClFN3
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1
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| 1 |
EC50 > 10000 nM
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CP0551895
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3,8-dimethyl-6-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
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C21H23N3
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1
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| 1 |
EC50 > 10000 nM
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CP0551896
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8-methoxy-3-methyl-6-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
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C21H23N3O
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1
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| 1 |
EC50 > 10000 nM
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CP0554624
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3-chloro-6-[(6S)-1,6-dimethyl-3,6-dihydro-2H-pyridin-4-yl]-8-fluoro-11H-benzo[b][1,4]benzodiazepine
Show/Hide
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C20H19ClFN3
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1
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| 1 |
EC50 > 10000 nM
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CP0570014
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3-chloro-8-fluoro-6-(1-propan-2-yl-3,6-dihydro-2H-pyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
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C21H21ClFN3
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1
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| 1 |
EC50 > 10000 nM
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CP0423460
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1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-pentylurea
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C14H26N6OS
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
Kd = 0.17 nM
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CP0543296
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1-[(1R)-1-phenylethyl]-3-[N'-[3-(1H-1,2,4-triazol-5-yl)propyl]carbamimidoyl]urea;dihydrochloride
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C15H23Cl2N7O
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
Kd = 0.17 nM
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CP0543300
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1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-benzylurea;2,2,2-trifluoroacetic acid
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C18H21F6N7O5S
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
Kd = 0.17 nM
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CP0551746
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1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-pentylurea;2,2,2-trifluoroacetic acid
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C16H25F6N7O5S
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
Kd = 0.17 nM
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CP0006743
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4-methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide
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C16H19NO3S
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2
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| 1 |
EC50 > 15848.93 nM
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| 2 |
IC50 > 15848.93 nM
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CP0438562
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1-Aza-bicyclo[2.2.1]heptan-3-one O-propyl-oxime
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C9H16N2O
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2
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| 1 |
EC50 = 27000 nM
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| 2 |
IC50 = 3680 nM
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CP0413445
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N-benzyl-1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-N-ethylpiperidine-4-carboxamide
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C23H28N2O5S
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1
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| 1 |
EC50 > 30000 nM
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CP0374379
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5-(1-Aza-bicyclo[2.2.1]hept-3-yl)-[1,2,4]oxadiazol-3-ylamine
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C8H12N4O
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2
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| 1 |
EC50 = 100000 nM
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| 2 |
IC50 = 400 nM
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CP0045063
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2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
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C17H20N4S
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2
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| 1 |
EC50 > 100000 nM
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| 2 |
Ki = 10 nM
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CP0550430
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N-[(1S,2S)-2,5-dihydroxycyclohexyl]-1-[(4-pyrazol-1-ylphenyl)methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C24H25N5O3
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1
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| 1 |
EC50 > 72 nM
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CP0550432
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N-[(4S,5R)-2,5-dihydroxyoxan-4-yl]-1-[[4-(1-methylpyrazol-3-yl)phenyl]methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C24H25N5O4
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1
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| 1 |
EC50 > 207 nM
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CP0394790
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N-[(6S)-2,6-dihydroxycyclohexyl]-1-[(4-pyrazol-1-ylphenyl)methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
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C24H25N5O3
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1
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| 1 |
EC50 > 249 nM
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CP0517716
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N-[(3R,4S)-2,3-dihydroxyoxan-4-yl]-1-[[4-(1-methylpyrazol-3-yl)phenyl]methyl]pyrrolo[3,2-b]pyridine-3-carboxamide
Show/Hide
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C24H25N5O4
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1
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| 1 |
EC50 > 257 nM
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CP0416848
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5-methyl-4-[(4-pyrazol-1-ylphenyl)methyl]-N-[(2R,3S)-1,2,5-trihydroxypentan-3-yl]pyridine-2-carboxamide
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C22H26N4O4
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1
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| 1 |
EC50 > 300 nM
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CP0538726
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N-[(3R,4S)-3-hydroxyoxan-4-yl]-4-[hydroxy-(4-pyrazol-1-ylphenyl)methyl]-5-methylpyridine-2-carboxamide
Show/Hide
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C22H24N4O4
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1
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| 1 |
EC50 > 1000 nM
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CP0517712
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N-[(4S,5R)-2,5-dihydroxyoxan-4-yl]-5-methyl-4-[(4-pyrazol-1-ylphenyl)methyl]pyridine-2-carboxamide
Show/Hide
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C22H24N4O4
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1
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| 1 |
EC50 > 3000 nM
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CP0553033
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2-amino-N-[(3R,4S)-3-hydroxyoxan-4-yl]-4-methyl-5-[(4-pyrazol-1-ylphenyl)methyl]benzamide
Show/Hide
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C23H26N4O3
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1
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| 1 |
EC50 > 9000 nM
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CP0566222
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N-[(3R,4S)-3-hydroxyoxan-4-yl]-4-[(4-pyrazol-1-ylphenyl)methyl]pyridine-2-carboxamide
Show/Hide
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C21H22N4O3
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1
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| 1 |
EC50 > 9000 nM
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CP0857826
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1-Cyclohexyl-1-phenyl-3-piperidin-1-yl-propan-1-ol hydrochloride
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C20H32ClNO
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1
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| 1 |
IC50 = 1.3 nM
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CP0918646
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8,8-dimethyl-3-(thiophen-3-yl-thiophen-3-ylmethyl-carbamoyloxy)-8-azonia-bicyclo[3.2.1]octane bromide
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C19H25BrN2O2S2
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1
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| 1 |
IC50 = 1.6 nM
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CP0040500
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3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9-aza-tricyclo[3.3.1.0*2,4*]non-7-yl ester
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C18H24NO4+
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2
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| 1 |
IC50 = 1.8 nM
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| 2 |
Ki = 0.3236 nM
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CP0913088
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3-(benzyl-thiophen-3-yl-carbamoyloxy)-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
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C21H27BrN2O2S
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1
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| 1 |
IC50 = 2.1 nM
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CP0037621
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(oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyrrolidin-2-one
Show/Hide
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C12H18N2O
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5
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| 1 |
IC50 = 2.3 nM
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| 2 |
IC50 = 9000 nM
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| 3 |
IC50 = 27100 nM
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| 4 |
Ki = 1.122 nM
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| 5 |
Ki = 17 nM
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CP0917877
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8,8-dimethyl-3-(phenyl-thiophen-2-ylmethyl-carbamoyloxy)-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
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C21H27BrN2O2S
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1
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| 1 |
IC50 = 2.4 nM
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CP0880755
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8,8-dimethyl-3-(phenyl-thiophen-3-ylmethyl-carbamoyloxy)-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
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C21H27BrN2O2S
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1
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| 1 |
IC50 = 2.6 nM
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CP0879643
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3-(benzyl-thiophen-2-yl-carbamoyloxy)-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
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C21H27BrN2O2S
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1
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| 1 |
IC50 = 2.7 nM
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CP0844749
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8,8-dimethyl-3-[(3-methyl-thiophen-2-ylmethyl)-phenyl-carbamoyloxy]-8-azonia-bicyclo[3.2.1]octane bromide
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C22H29BrN2O2S
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1
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| 1 |
IC50 = 3.8 nM
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CP0854409
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3-(benzyl-phenyl-carbamoyloxy)-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
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C23H29BrN2O2
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1
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| 1 |
IC50 = 4.5 nM
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CP0192149
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(R)-8-(3-aminopiperidin-1-yl)-1-(isoquinolin-1-ylmethyl)-3-methyl-7-(3-methylbut-2-enyl)-1H-purine-2,6(3H,7H)-dione
Show/Hide
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C26H31N7O2
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1
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| 1 |
IC50 = 5 nM
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CP0848260
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(S)-6-((3-(4-hydroxyphenyl)-2-(3-(4-(isopropoxycarbonyl)phenyl)ureido)propanamido)methyl)-3,7-dimethyl-7H-imidazo[2,1-b]thiazol-4-ium
Show/Hide
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C28H32N5O5S+
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1
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| 1 |
IC50 < 5 nM
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CP0856414
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(S)-7-(4-chlorobenzyl)-6-((3-(4-hydroxyphenyl)-2-(3-(4-(isopropoxycarbonyl)phenyl)ureido)propanamido)methyl)-3-methyl-7H-imidazo[2,1-b]thiazol-4-ium
Show/Hide
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C34H35ClN5O5S+
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1
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| 1 |
IC50 < 5 nM
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CP0935330
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(S)-6-((3-(4-hydroxyphenyl)-2-(3-(4-(isopropoxycarbonyl)phenyl)ureido)propanamido)methyl)-2,7-dimethyl-7H-imidazo[2,1-b]thiazol-4-ium
Show/Hide
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C28H32N5O5S+
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1
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| 1 |
IC50 < 5 nM
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CP0913094
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3-(cyclohexylmethyl-thiophen-3-yl-carbamoyloxy)-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
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C21H33BrN2O2S
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1
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| 1 |
IC50 = 5.8 nM
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CP0847735
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 2-p-tolyl-ethyl ester oxalic acid
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C25H29NO6
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1
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| 1 |
IC50 = 8.8 nM
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CP0847169
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid phenethyl ester oxalic acid
Show/Hide
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C24H27NO6
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1
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| 1 |
IC50 = 9.6 nM
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CP0914882
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(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-3-(4-benzoylphenyl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-methylpyrrolidinium
Show/Hide
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C39H41IN4O7
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1
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| 1 |
IC50 = 10 nM
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CP0847624
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2-(endo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)-1,1-diphenylethanol
Show/Hide
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C22H27NO
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3
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.7943 nM
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| 3 |
Ki = 0.5012 nM
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CP0858919
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(3-endo)-3-(3-Hydroxy-2,2-diphenylpropyl)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane Bromide
Show/Hide
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C24H32BrNO
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3
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 1.585 nM
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| 3 |
Ki = 1.259 nM
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CP0858933
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3-[(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenylpropanenitrile
Show/Hide
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C23H26N2
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3
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.01585 nM
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| 3 |
Ki = 0.1 nM
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CP0867929
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(3-endo)-3-(2-Cyano-2,2-diphenylethyl)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane Bromide
Show/Hide
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C24H29BrN2
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3
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| 1 |
IC50 < 10 nM
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| 2 |
Ki = 0.05 nM
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| 3 |
Ki = 0.05012 nM
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CP0870156
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3-[(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenyl-1-propanol
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C23H29NO
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3
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 1.259 nM
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| 3 |
Ki = 1 nM
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CP0906476
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endo-3-(2-hydroxy-2,2-diphenylethyl)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane bromide
Show/Hide
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C23H30BrNO
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3
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.2512 nM
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| 3 |
Ki = 1.585 nM
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CP0404712
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid nonyl ester
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C23H35NO2
|
1
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| 1 |
IC50 = 11.5 nM
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CP0913085
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3-(furan-3-ylmethyl-phenyl-carbamoyloxy)-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
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C21H27BrN2O3
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1
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| 1 |
IC50 = 12.2 nM
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CP0919122
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(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-3-(biphenyl-4-yl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-methylpyrrolidinium
Show/Hide
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C38H41IN4O6
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1
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| 1 |
IC50 = 12.59 nM
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CP0374705
|
ethyl 17-methoxy-6,7,7-trimethyl-12-oxa-1-aza-7-azoniapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate;iodide
Show/Hide
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C25H29IN2O4
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2
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| 1 |
IC50 = 12.7 nM
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| 2 |
IC50 = 24.5 nM
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CP0408782
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1-adamantyl-[2-[[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]ethyl]-dimethylazanium
Show/Hide
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C34H47N4O5+
|
1
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| 1 |
IC50 = 13.1 nM
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CP0870135
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid benzyl ester hydrochloride
Show/Hide
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C21H24ClNO2
|
1
|
| 1 |
IC50 = 13.4 nM
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CP0854410
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl thiophen-3-yl(thiophen-3-ylmethyl)carbamate
Show/Hide
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C18H22N2O2S2
|
1
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| 1 |
IC50 = 13.8 nM
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CP0845078
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid cyclohexylmethyl ester oxalic acid
Show/Hide
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C23H31NO6
|
1
|
| 1 |
IC50 = 14.5 nM
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CP0913098
|
8,8-dimethyl-3-[(3-methyl-furan-2-ylmethyl)-phenyl-carbamoyloxy]-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
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C22H29BrN2O3
|
1
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| 1 |
IC50 = 15.2 nM
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CP0920181
|
8,8-dimethyl-3-[(5-methyl-thiophen-2-ylmethyl)-phenyl-carbamoyloxy]-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
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C22H29BrN2O2S
|
1
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| 1 |
IC50 = 15.8 nM
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CP0849760
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid cyclohexyl ester oxalic acid
Show/Hide
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C22H29NO6
|
1
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| 1 |
IC50 = 16.9 nM
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CP0854268
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid cyclohexyl ester oxalic acid
Show/Hide
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C22H29NO6
|
1
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| 1 |
IC50 = 18.1 nM
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CP0879640
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8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl benzyl(thiophen-3-yl)carbamate
Show/Hide
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C20H24N2O2S
|
1
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| 1 |
IC50 = 19.1 nM
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CP0056034
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11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
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C19H21N5O2
|
9
|
| 1 |
IC50 = 21 nM
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| 2 |
IC50 = 27 nM
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| 3 |
IC50 = 28.2 nM
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| 4 |
IC50 = 119 nM
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| 5 |
Ki = 15 nM
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| 6 |
Ki = 16 nM
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| 7 |
Ki = 20 nM
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| 8 |
Ki = 21.38 nM
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| 9 |
Ki = 24 nM
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CP0850038
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid octyl ester oxalic acid
Show/Hide
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C24H35NO6
|
1
|
| 1 |
IC50 = 22 nM
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CP0654244
|
3-[(Z)-3-Chloro-isoxazol-5-ylmethoxyimino]-1-azonia-bicyclo[2.2.1]heptane chloride
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C10H13Cl2N3O2
|
2
|
| 1 |
IC50 = 23 nM
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| 2 |
IC50 = 36300 nM
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CP0075223
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8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methyl-but-2-enyl)-1-(2-oxo-2-phenyl-ethyl)-3,7-dihydro-purine-2,6-dione
Show/Hide
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C24H30N6O3
|
1
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| 1 |
IC50 = 25 nM
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CP0928833
|
(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-3-(3-chlorophenyl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-methylpyrrolidinium
Show/Hide
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C32H36ClIN4O6
|
1
|
| 1 |
IC50 = 25.12 nM
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CP0159038
|
(S)-8-(3-aminopiperidin-1-yl)-1-(isoquinolin-1-ylmethyl)-3-methyl-7-(3-methylbut-2-enyl)-1H-purine-2,6(3H,7H)-dione
Show/Hide
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C26H31N7O2
|
1
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| 1 |
IC50 = 26 nM
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CP0861075
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid hexyl ester oxalic acid
Show/Hide
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C22H31NO6
|
1
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| 1 |
IC50 = 27.3 nM
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CP0457550
|
3-(4-butoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,6-tetrahydropyridine
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C12H19N3OS
|
2
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| 1 |
IC50 = 28.18 nM
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| 2 |
IC50 = 77624.71 nM
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CP0381434
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid nonyl ester
Show/Hide
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C23H35NO2
|
1
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| 1 |
IC50 = 30.4 nM
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CP0858371
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(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-3-(4-bromophenyl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-methylpyrrolidinium
Show/Hide
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C32H36BrIN4O6
|
1
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| 1 |
IC50 = 31.62 nM
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CP0496640
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1-Methyl-5-(4-pentyloxy-[1,2,5]thiadiazol-3-yl)-1,2,3,6-tetrahydro-pyridine
Show/Hide
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C13H21N3OS
|
2
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| 1 |
IC50 = 33.11 nM
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| 2 |
IC50 = 8511.38 nM
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CP0873209
|
3-[(4-bromo-benzyl)-phenyl-carbamoyloxy]-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
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C23H28Br2N2O2
|
1
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| 1 |
IC50 = 33.4 nM
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CP0878826
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid hexyl ester oxalic acid
Show/Hide
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C22H31NO6
|
1
|
| 1 |
IC50 = 35 nM
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CP0403635
|
1-Methyl-5-[4-(3-phenyl-prop-2-ynyloxy)-[1,2,5]thiadiazol-3-yl]-1,2,3,6-tetrahydro-pyridine
Show/Hide
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C17H17N3OS
|
2
|
| 1 |
IC50 = 37.15 nM
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| 2 |
IC50 = 2137.96 nM
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CP0869657
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 2-cyclohexyl-ethyl ester oxalic acid
Show/Hide
|
C24H33NO6
|
1
|
| 1 |
IC50 = 38.7 nM
|
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CP0858375
|
(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-3-(3,4-dichlorophenyl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-methylpyrrolidinium
Show/Hide
|
C32H35Cl2IN4O6
|
1
|
| 1 |
IC50 = 39.81 nM
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CP0904301
|
(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-3-(4-chlorophenyl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-methylpyrrolidinium
Show/Hide
|
C32H36ClIN4O6
|
1
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| 1 |
IC50 = 39.81 nM
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CP0756946
|
3-[(3-Chloro-isoxazol-5-ylmethoxyimino)-methyl]-1-azonia-bicyclo[2.2.1]heptane chloride
Show/Hide
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C11H15Cl2N3O2
|
2
|
| 1 |
IC50 = 44 nM
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| 2 |
IC50 = 14900 nM
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CP0918645
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl benzyl(thiophen-2-yl)carbamate
Show/Hide
|
C20H24N2O2S
|
1
|
| 1 |
IC50 = 45.1 nM
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CP0879642
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8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl phenyl(thiophen-2-ylmethyl)carbamate
Show/Hide
|
C20H24N2O2S
|
1
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| 1 |
IC50 = 48.3 nM
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CP0059084
|
8-((S)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methyl-but-2-enyl)-1-(2-oxo-2-phenyl-ethyl)-3,7-dihydro-purine-2,6-dione
Show/Hide
|
C24H30N6O3
|
1
|
| 1 |
IC50 = 50 nM
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CP0914881
|
(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)-3-(4-(trifluoromethyl)phenyl)propanamido)-1-methylpyrrolidinium
Show/Hide
|
C33H36F3IN4O6
|
1
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| 1 |
IC50 = 50.12 nM
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CP0424097
|
1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,3,6-tetrahydro-pyridine
Show/Hide
|
C11H17N3OS
|
1
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| 1 |
IC50 = 52.48 nM
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CP0860558
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid cyclohexylmethyl ester oxalic acid
Show/Hide
|
C23H31NO6
|
1
|
| 1 |
IC50 = 54.2 nM
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CP0854414
|
3-[(3-cyano-benzyl)-thiophen-3-yl-carbamoyloxy]-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C22H26BrN3O2S
|
1
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| 1 |
IC50 = 55.6 nM
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CP0723936
|
3-[(Z)-3-Chloro-isoxazol-5-ylmethoxyimino]-1-azonia-bicyclo[2.2.2]octane chloride
Show/Hide
|
C11H15Cl2N3O2
|
2
|
| 1 |
IC50 = 57 nM
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| 2 |
IC50 = 13800 nM
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CP0467740
|
ethyl 5-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]pentanoate
Show/Hide
|
C15H23N3O3S
|
1
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| 1 |
IC50 = 58.88 nM
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CP0914385
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 3-phenyl-propyl ester hydrochloride
Show/Hide
|
C23H28ClNO2
|
1
|
| 1 |
IC50 = 59.2 nM
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CP0878820
|
(3R,4R)-1-Ethyl-4-phenyl-piperidine-3-carboxylic acid hexyl ester oxalic acid
Show/Hide
|
C22H33NO6
|
1
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| 1 |
IC50 = 61.4 nM
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CP0861085
|
1-Ethyl-4-phenyl-piperidine-3-carboxylic acid phenethyl ester oxalic acid
Show/Hide
|
C24H29NO6
|
1
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| 1 |
IC50 = 62.4 nM
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CP0860587
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid pentyl ester oxalic acid
Show/Hide
|
C21H29NO6
|
1
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| 1 |
IC50 = 63.7 nM
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CP0854470
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid benzyl ester hydrochloride
Show/Hide
|
C21H24ClNO2
|
1
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| 1 |
IC50 = 65.4 nM
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CP0869546
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid butyl ester oxalic acid
Show/Hide
|
C20H27NO6
|
1
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| 1 |
IC50 = 67.9 nM
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CP0849717
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 4-phenyl-butyl ester oxalic acid
Show/Hide
|
C26H31NO6
|
1
|
| 1 |
IC50 = 69.4 nM
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CP0735794
|
3-[(Z)-3-Bromo-isoxazol-5-ylmethoxyimino]-1-azonia-bicyclo[2.2.2]octane chloride
Show/Hide
|
C11H15BrClN3O2
|
2
|
| 1 |
IC50 = 72 nM
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| 2 |
IC50 = 11500 nM
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CP0920525
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl phenyl(thiophen-3-ylmethyl)carbamate
Show/Hide
|
C20H24N2O2S
|
1
|
| 1 |
IC50 = 73.8 nM
|
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CP0896081
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 4-cyanobenzyl(thiophen-3-yl)carbamate
Show/Hide
|
C21H23N3O2S
|
1
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| 1 |
IC50 = 75.8 nM
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CP0849749
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid butyl ester oxalic acid
Show/Hide
|
C20H27NO6
|
1
|
| 1 |
IC50 = 76.8 nM
|
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CP0914612
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid octyl ester oxalic acid
Show/Hide
|
C24H35NO6
|
1
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| 1 |
IC50 = 77.3 nM
|
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CP0886216
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid heptyl ester oxalic acid
Show/Hide
|
C23H33NO6
|
1
|
| 1 |
IC50 = 78 nM
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CP0841044
|
3-[(Z)-3-Bromo-isoxazol-5-ylmethoxyimino]-1-azonia-bicyclo[2.2.1]heptane chloride
Show/Hide
|
C10H13BrClN3O2
|
2
|
| 1 |
IC50 = 79 nM
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| 2 |
IC50 = 48800 nM
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CP0869979
|
(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)-3-(4-methoxyphenyl)propanamido)-1-methylpyrrolidinium
Show/Hide
|
C33H39IN4O7
|
1
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| 1 |
IC50 = 79.43 nM
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CP0794424
|
3-[(Z)-3-Cyano-isoxazol-5-ylmethoxyimino]-1-azonia-bicyclo[2.2.2]octane chloride
Show/Hide
|
C12H15ClN4O2
|
2
|
| 1 |
IC50 = 81 nM
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| 2 |
IC50 = 8700 nM
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CP0900176
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3-[(Z)-3-Cyano-isoxazol-5-ylmethoxyimino]-1-azonia-bicyclo[2.2.1]heptane chloride
Show/Hide
|
C11H13ClN4O2
|
2
|
| 1 |
IC50 = 82 nM
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| 2 |
IC50 = 32500 nM
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CP0916155
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8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl furan-3-ylmethyl(phenyl)carbamate
Show/Hide
|
C20H24N2O3
|
1
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| 1 |
IC50 = 84.5 nM
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CP0854465
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid pentyl ester oxalic acid
Show/Hide
|
C21H29NO6
|
1
|
| 1 |
IC50 = 84.8 nM
|
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CP0896083
|
3-[(4-methoxy-benzyl)-phenyl-carbamoyloxy]-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C24H31BrN2O3
|
1
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| 1 |
IC50 = 86 nM
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CP0458033
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2-[(3R)-3-aminopiperidin-1-yl]-3-but-2-ynyl-7-methyl-5-[(4-methylquinazolin-2-yl)methyl]imidazo[4,5-d]pyridazin-4-one
Show/Hide
|
C25H28N8O
|
1
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| 1 |
IC50 = 93 nM
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CP0860615
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 2-p-tolyl-ethyl ester oxalic acid
Show/Hide
|
C25H29NO6
|
1
|
| 1 |
IC50 = 93.5 nM
|
|
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CP0867851
|
(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)-3-(4-fluorophenyl)propanamido)-1-methylpyrrolidinium
Show/Hide
|
C32H36FIN4O6
|
1
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| 1 |
IC50 = 100 nM
|
|
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CP0867852
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(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)-3-p-tolylpropanamido)-1-methylpyrrolidinium
Show/Hide
|
C33H39IN4O6
|
1
|
| 1 |
IC50 = 100 nM
|
|
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CP0891440
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(3S)-3-((S)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)-3-(4-hydroxyphenyl)propanamido)-1-(4-fluorobenzyl)-1-methylpiperidinium
Show/Hide
|
C32H38FIN4O5
|
1
|
| 1 |
IC50 = 100 nM
|
|
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CP0920358
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(3-endo)-8-Methyl-3-(2,2,2-triphenylethyl)-8-azabicyclo[3.2.1]-octane
Show/Hide
|
C28H31N
|
1
|
| 1 |
IC50 = 105 nM
|
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CP0859753
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 2-cyclohexyl-ethyl ester oxalic acid
Show/Hide
|
C24H33NO6
|
1
|
| 1 |
IC50 = 105.2 nM
|
|
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CP0392493
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid decyl ester
Show/Hide
|
C24H37NO2
|
1
|
| 1 |
IC50 = 106.1 nM
|
|
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CP0430477
|
3-[1-{3-[3,4-Bis-(4-methoxy-benzyloxy)-phenyl]-isoxazol-5-yl}-meth-(Z)-ylidene]-1-aza-bicyclo[2.2.1]heptane
Show/Hide
|
C32H32N2O5
|
1
|
| 1 |
IC50 = 114 nM
|
|
|
|
CP0018455
|
1-methyl-3,6-dihydro-2H-pyridine-5-carboxylic acid methyl ester;hydrobromide
Show/Hide
|
C8H13NO2
|
3
|
| 1 |
IC50 = 115 nM
|
|
|
| 2 |
Ki = 14 nM
|
|
|
| 3 |
Ki = 29512.09 nM
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CP0881236
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl (3-methylthiophen-2-yl)methyl(phenyl)carbamate
Show/Hide
|
C21H26N2O2S
|
1
|
| 1 |
IC50 = 117.3 nM
|
|
|
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CP0847343
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid isobutyl ester oxalic acid
Show/Hide
|
C20H27NO6
|
1
|
| 1 |
IC50 = 120.5 nM
|
|
|
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CP0853934
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 3-phenyl-propyl ester hydrochloride
Show/Hide
|
C23H28ClNO2
|
1
|
| 1 |
IC50 = 122 nM
|
|
|
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CP0844748
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl cyclohexylmethyl(thiophen-3-yl)carbamate
Show/Hide
|
C20H30N2O2S
|
1
|
| 1 |
IC50 = 125.5 nM
|
|
|
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CP0863347
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid isobutyl ester oxalic acid
Show/Hide
|
C20H27NO6
|
1
|
| 1 |
IC50 = 128 nM
|
|
|
|
CP0672354
|
3-[(Z)-3-Methoxy-isoxazol-5-ylmethoxyimino]-1-azonia-bicyclo[2.2.1]heptane chloride
Show/Hide
|
C11H16ClN3O3
|
2
|
| 1 |
IC50 = 131 nM
|
|
|
| 2 |
IC50 = 40540 nM
|
|
|
|
CP0414826
|
propan-2-yl 4-[[(2S)-1-[4-[(4-chlorophenyl)methyl]-4-(cyclohexylmethyl)piperazin-4-ium-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C38H48ClN4O5+
|
1
|
| 1 |
IC50 = 141 nM
|
|
|
|
CP0441009
|
3-(3-(ethoxy)-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetrahydro-1-methylpyridine
Show/Hide
|
C10H15N3OS
|
1
|
| 1 |
IC50 = 141.25 nM
|
|
|
|
CP0453234
|
1-Methyl-5-[4-(4-phenyl-butoxy)-[1,2,5]thiadiazol-3-yl]-1,2,3,6-tetrahydro-pyridine
Show/Hide
|
C18H23N3OS
|
2
|
| 1 |
IC50 = 144.54 nM
|
|
|
| 2 |
IC50 = 9120.11 nM
|
|
|
|
CP0484598
|
N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
|
C26H27N3O3
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0894403
|
(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)-3-(4-hydroxyphenyl)propanamido)-1-methylpyrrolidinium
Show/Hide
|
C32H37IN4O7
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0861083
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 2-(4-methoxy-phenyl)-ethyl ester oxalic acid
Show/Hide
|
C25H29NO7
|
1
|
| 1 |
IC50 = 159 nM
|
|
|
|
CP0854413
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl benzyl(phenyl)carbamate
Show/Hide
|
C22H26N2O2
|
1
|
| 1 |
IC50 = 161.3 nM
|
|
|
|
CP0850036
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid heptyl ester oxalic acid
Show/Hide
|
C23H33NO6
|
1
|
| 1 |
IC50 = 161.4 nM
|
|
|
|
CP0502045
|
3-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-1-amine
Show/Hide
|
C11H18N4OS
|
2
|
| 1 |
IC50 = 162.18 nM
|
|
|
| 2 |
IC50 = 14791.08 nM
|
|
|
|
CP0399182
|
propan-2-yl 4-[[(2S)-1-[2-[1-[(4-chlorophenyl)methyl]piperidin-1-ium-1-yl]ethylamino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C34H42ClN4O5+
|
1
|
| 1 |
IC50 = 198.8 nM
|
|
|
|
CP0916599
|
(3S)-3-((S)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)-3-(4-hydroxyphenyl)propanamido)-1-(4-fluorobenzyl)-1-methylpyrrolidinium
Show/Hide
|
C31H36FIN4O5
|
1
|
| 1 |
IC50 = 199.53 nM
|
|
|
|
CP0913086
|
3-[(3-bromo-benzyl)-phenyl-carbamoyloxy]-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C23H28Br2N2O2
|
1
|
| 1 |
IC50 = 210.3 nM
|
|
|
|
CP0469910
|
(3Z)-1-azabicyclo[2.2.1]heptan-3-oneO-[(2E)-pent-2-en-4-ynyl]oxime
Show/Hide
|
C11H14N2O
|
2
|
| 1 |
IC50 = 216 nM
|
|
|
| 2 |
IC50 = 12600 nM
|
|
|
|
CP0464771
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-(3-methyl-but-2-enyl)-oxime
Show/Hide
|
C11H18N2O
|
1
|
| 1 |
IC50 = 216 nM
|
|
|
|
CP0459815
|
3-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-4-(4-pyrrol-1-ylbutoxy)-1,2,5-thiadiazole
Show/Hide
|
C16H22N4OS
|
6
|
| 1 |
IC50 = 218.78 nM
|
|
|
| 2 |
IC50 = 275.42 nM
|
|
|
| 3 |
IC50 = 407.38 nM
|
|
|
| 4 |
IC50 = 12022.64 nM
|
|
|
| 5 |
IC50 = 28840.32 nM
|
|
|
| 6 |
IC50 = 39810.72 nM
|
|
|
|
CP0914469
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid phenethyl ester oxalic acid
Show/Hide
|
C24H27NO6
|
1
|
| 1 |
IC50 = 233.6 nM
|
|
|
|
CP0374699
|
3-[1-{3-[3,4-Bis-(4-methoxy-benzyloxy)-phenyl]-isoxazol-5-yl}-meth-(E)-ylidene]-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C33H34N2O5
|
1
|
| 1 |
IC50 = 247 nM
|
|
|
|
CP0395418
|
3-[1-{3-[4-(4-Methoxy-benzyloxy)-phenyl]-isoxazol-5-yl}-meth-(E)-ylidene]-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C25H26N2O3
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0389547
|
[1-[6-(2,4-difluorophenoxy)pyrimidin-4-yl]piperidin-4-yl]-(3,4-dihydro-1H-isoquinolin-2-yl)methanone
Show/Hide
|
C25H24F2N4O2
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0440676
|
ethyl 4-[[(2S)-1-[[1-[(3-cyanophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C31H33N5O5
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0858370
|
(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-3-(4-cyanophenyl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-methylpyrrolidinium
Show/Hide
|
C33H36IN5O6
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0891438
|
(3S)-3-((S)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)-3-(4-hydroxyphenyl)propanamido)-1-(4-hydroxybenzyl)-1-methylpyrrolidinium
Show/Hide
|
C31H37IN4O6
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0854408
|
3-[(4-cyano-benzyl)-phenyl-carbamoyloxy]-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C24H28BrN3O2
|
1
|
| 1 |
IC50 = 257.9 nM
|
|
|
|
CP0397501
|
3-[1-{3-[3,4-Bis-(4-methoxy-benzyloxy)-phenyl]-isoxazol-5-yl}-meth-(Z)-ylidene]-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C33H34N2O5
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0903854
|
3-[(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenylpropanoic Acid
Show/Hide
|
C23H27NO2
|
1
|
| 1 |
IC50 = 277 nM
|
|
|
|
CP0889381
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid propyl ester oxalic acid
Show/Hide
|
C19H25NO6
|
1
|
| 1 |
IC50 = 278 nM
|
|
|
|
CP0741336
|
3-[(3-Methoxy-isoxazol-5-ylmethoxyimino)-methyl]-1-azonia-bicyclo[2.2.1]heptane chloride
Show/Hide
|
C12H18ClN3O3
|
2
|
| 1 |
IC50 = 287 nM
|
|
|
| 2 |
IC50 = 16700 nM
|
|
|
|
CP0456704
|
4-[4-[6-(3,3-dimethylpiperidin-1-yl)pyridazin-3-yl]piperazin-1-yl]sulfonyl-3,5-dimethyl-1,2-oxazole
Show/Hide
|
C20H30N6O3S
|
1
|
| 1 |
IC50 = 288 nM
|
|
|
|
CP0910088
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid propyl ester oxalic acid
Show/Hide
|
C19H25NO6
|
1
|
| 1 |
IC50 = 291.2 nM
|
|
|
|
CP0079344
|
(R)-8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione
Show/Hide
|
C25H28N8O2
|
1
|
| 1 |
IC50 = 295 nM
|
|
|
|
CP0535930
|
4-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]butan-1-ol
Show/Hide
|
C12H19N3O2S
|
1
|
| 1 |
IC50 = 309.03 nM
|
|
|
|
CP0389549
|
[1-[6-(4-chlorophenoxy)pyrimidin-4-yl]piperidin-4-yl]-(3,4-dihydro-1H-isoquinolin-2-yl)methanone
Show/Hide
|
C25H25ClN4O2
|
1
|
| 1 |
IC50 = 313 nM
|
|
|
|
CP0845389
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 5-phenyl-pentyl ester oxalic acid
Show/Hide
|
C27H33NO6
|
1
|
| 1 |
IC50 = 316.7 nM
|
|
|
|
CP0338181
|
N-[3-[4-(5-bromopyridin-2-yl)piperazin-1-yl]-3-oxopropyl]-2,1,3-benzothiadiazole-4-sulfonamide
Show/Hide
|
C18H19BrN6O3S2
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0389544
|
3,4-dihydro-1H-isoquinolin-2-yl-[1-[6-(2-fluorophenoxy)pyrimidin-4-yl]piperidin-4-yl]methanone
Show/Hide
|
C25H25FN4O2
|
1
|
| 1 |
IC50 = 322 nM
|
|
|
|
CP0480882
|
propan-2-yl 4-[[(2S)-1-[[1,3-bis[(4-chlorophenyl)methyl]imidazol-1-ium-2-yl]methylamino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C38H38Cl2N5O5+
|
1
|
| 1 |
IC50 = 327.2 nM
|
|
|
|
CP0756945
|
3-[(3-Cyano-isoxazol-5-ylmethoxyimino)-methyl]-1-azonia-bicyclo[2.2.2]octane chloride
Show/Hide
|
C13H17ClN4O2
|
1
|
| 1 |
IC50 = 341 nM
|
|
|
|
CP0896082
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl (3-methylfuran-2-yl)methyl(phenyl)carbamate
Show/Hide
|
C21H26N2O3
|
1
|
| 1 |
IC50 = 349.2 nM
|
|
|
|
CP0727235
|
3-[(Z)-3-Methoxy-isoxazol-5-ylmethoxyimino]-1-azonia-bicyclo[2.2.2]octane chloride
Show/Hide
|
C12H18ClN3O3
|
2
|
| 1 |
IC50 = 362 nM
|
|
|
| 2 |
IC50 = 35600 nM
|
|
|
|
CP0523854
|
bis[(4-chlorophenyl)methyl]-[2-[[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]ethyl]-methylazanium
Show/Hide
|
C37H41Cl2N4O5+
|
1
|
| 1 |
IC50 = 378.6 nM
|
|
|
|
CP0827169
|
3-[(3-Bromo-isoxazol-5-ylmethoxyimino)-methyl]-1-azonia-bicyclo[2.2.1]heptane chloride
Show/Hide
|
C11H15BrClN3O2
|
2
|
| 1 |
IC50 = 385 nM
|
|
|
| 2 |
IC50 = 17700 nM
|
|
|
|
CP0393505
|
N-[3-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)propyl]quinoline-5-sulfonamide
Show/Hide
|
C21H23N5O3S
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0499985
|
propan-2-yl 4-[[(2S)-1-[2-[1-[(4-chlorophenyl)methyl]pyrrolidin-1-ium-1-yl]ethylamino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C33H40ClN4O5+
|
1
|
| 1 |
IC50 = 417.9 nM
|
|
|
|
CP0854411
|
3-[(2-bromo-benzyl)-phenyl-carbamoyloxy]-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C23H28Br2N2O2
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0053807
|
(R)-8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-3-methyl-1-((3-methylisoquinolin-1-yl)methyl)-1H-purine-2,6(3H,7H)-dione
Show/Hide
|
C26H29N7O2
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0432439
|
[1-(2,1,3-benzoxadiazol-4-ylsulfonyl)azetidin-3-yl]-(4-pyridin-4-ylpiperazin-1-yl)methanone
Show/Hide
|
C19H20N6O4S
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0077509
|
1-[(4-methoxyphenyl)methyl]-4-oxo-N-[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]quinoline-3-carboxamide
Show/Hide
|
C34H34N4O3
|
1
|
| 1 |
IC50 = 455 nM
|
|
|
|
CP0391914
|
propan-2-yl 4-[[(2S)-1-[4-[(4-chlorophenyl)methyl]-4-(1,2,3,4-tetrahydronaphthalen-2-ylmethyl)piperazin-4-ium-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C42H48ClN4O5+
|
1
|
| 1 |
IC50 = 462.4 nM
|
|
|
|
CP0391915
|
(4-chlorophenyl)methyl-[3-[[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]-2,2-dimethylpropyl]-dimethylazanium
Show/Hide
|
C34H44ClN4O5+
|
1
|
| 1 |
IC50 = 476 nM
|
|
|
|
CP0392206
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid decyl ester
Show/Hide
|
C24H37NO2
|
1
|
| 1 |
IC50 = 484.2 nM
|
|
|
|
CP0440677
|
ethyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[1-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C31H36N4O6
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0187017
|
(R)-1-(4-methoxybenzyl)-8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione
Show/Hide
|
C23H28N6O3
|
1
|
| 1 |
IC50 = 518 nM
|
|
|
|
CP0913092
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl (5-methylthiophen-2-yl)methyl(phenyl)carbamate
Show/Hide
|
C21H26N2O2S
|
1
|
| 1 |
IC50 = 518.1 nM
|
|
|
|
CP0356645
|
[1-[6-(2,4-difluorophenoxy)pyrimidin-4-yl]piperidin-4-yl]-(1,3-dihydroisoindol-2-yl)methanone
Show/Hide
|
C24H22F2N4O2
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0054849
|
(3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methyl-6-(S)-methyl-piperidin-2-yl)-vinyl]-decahydro-naphtho[2,3-c]furan-1-one
Show/Hide
|
C22H35NO2
|
2
|
| 1 |
IC50 = 548.2 nM
|
|
|
| 2 |
Ki = 107.15 nM
|
|
|
|
CP0408783
|
(4-chlorophenyl)methyl-diethyl-[2-[[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]ethyl]azanium
Show/Hide
|
C33H42ClN4O5+
|
1
|
| 1 |
IC50 = 584.3 nM
|
|
|
|
CP0858934
|
3-[(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenyl-N-(phenylmethyl)propanamide
Show/Hide
|
C30H34N2O
|
1
|
| 1 |
IC50 = 596 nM
|
|
|
|
CP0863310
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 3-cyclohexyl-propyl ester oxalic acid
Show/Hide
|
C25H35NO6
|
1
|
| 1 |
IC50 = 610.6 nM
|
|
|
|
CP0844751
|
3-[(3-methoxy-benzyl)-phenyl-carbamoyloxy]-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C24H31BrN2O3
|
1
|
| 1 |
IC50 = 611.8 nM
|
|
|
|
CP0510873
|
2-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]acetic acid
Show/Hide
|
C10H13N3O3S
|
1
|
| 1 |
IC50 = 616.6 nM
|
|
|
|
CP0493287
|
ethyl 4-[[(2S)-1-[[1-(cyclopropylmethyl)pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C27H34N4O5
|
1
|
| 1 |
IC50 = 630.96 nM
|
|
|
|
CP0894397
|
(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-3-(3,4-dimethoxyphenyl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-methylpyrrolidinium
Show/Hide
|
C34H41IN4O8
|
1
|
| 1 |
IC50 = 630.96 nM
|
|
|
|
CP0702373
|
N-(4-{4-[(6-Butyl-8-quinolinyl)oxy]-1-piperidinyl}butyl)ethanesulfonamide dihydrochloride
Show/Hide
|
C24H39Cl2N3O3S
|
1
|
| 1 |
IC50 = 630.96 nM
|
|
|
|
CP0510874
|
6-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]hexan-1-amine
Show/Hide
|
C14H24N4OS
|
2
|
| 1 |
IC50 = 645.65 nM
|
|
|
| 2 |
IC50 = 3981.07 nM
|
|
|
|
CP0082780
|
1-[(4-methoxyphenyl)methyl]-4-oxo-N-[2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethyl]quinoline-3-carboxamide
Show/Hide
|
C33H32N4O3
|
1
|
| 1 |
IC50 = 658 nM
|
|
|
|
CP0847170
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 5-phenyl-pentyl ester oxalic acid
Show/Hide
|
C27H33NO6
|
1
|
| 1 |
IC50 = 670 nM
|
|
|
|
CP0467479
|
N-[3-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)propyl]-2,1,3-benzothiadiazole-4-sulfonamide
Show/Hide
|
C18H20N6O3S2
|
1
|
| 1 |
IC50 = 690 nM
|
|
|
|
CP0913087
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 4-methoxybenzyl(phenyl)carbamate
Show/Hide
|
C23H28N2O3
|
1
|
| 1 |
IC50 = 734.4 nM
|
|
|
|
CP0391919
|
3-[[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]propyl-dimethyl-(naphthalen-2-ylmethyl)azanium
Show/Hide
|
C36H43N4O5+
|
1
|
| 1 |
IC50 = 734.4 nM
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CP0853885
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 4-phenyl-butyl ester oxalic acid
Show/Hide
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C26H31NO6
|
1
|
| 1 |
IC50 = 743.1 nM
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CP0391918
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(4-chlorophenyl)methyl-[3-[[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]propyl]-dimethylazanium
Show/Hide
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C32H40ClN4O5+
|
1
|
| 1 |
IC50 = 756.5 nM
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CP0846159
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N-{3-[(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenylpropyl}benzenesulfonamide
Show/Hide
|
C29H34N2O2S
|
1
|
| 1 |
IC50 = 770 nM
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CP0522818
|
ethyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[1-[(3-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
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C30H34N4O6
|
1
|
| 1 |
IC50 = 794.33 nM
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CP0731130
|
3-[(3-Chloro-isoxazol-5-ylmethoxyimino)-methyl]-1-azonia-bicyclo[2.2.2]octane chloride
Show/Hide
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C12H17Cl2N3O2
|
2
|
| 1 |
IC50 = 795 nM
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|
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| 2 |
IC50 = 23500 nM
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CP0899541
|
(4-{5-[1-Aza-bicyclo[2.2.2]oct-(3E)-ylidenemethyl]-isoxazol-3-yl}-phenyl)-carbamic acid tert-butyl ester
Show/Hide
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C22H27N3O3
|
1
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| 1 |
IC50 = 806 nM
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CP0404234
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3-[1-{3-[4-(4-Methoxy-benzyloxy)-phenyl]-isoxazol-5-yl}-meth-(Z)-ylidene]-1-aza-bicyclo[2.2.2]octane
Show/Hide
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C25H26N2O3
|
1
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| 1 |
IC50 = 809 nM
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CP0873200
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 4-bromobenzyl(phenyl)carbamate
Show/Hide
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C22H25BrN2O2
|
1
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| 1 |
IC50 = 812.8 nM
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CP0873205
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8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 4-cyanobenzyl(phenyl)carbamate
Show/Hide
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C23H25N3O2
|
1
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| 1 |
IC50 = 847.4 nM
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CP0437329
|
4-[[2-(3-aminopiperidin-1-yl)-3-but-2-ynyl-4-oxoimidazo[4,5-d]pyridazin-5-yl]methyl]naphthalene-1-carbonitrile
Show/Hide
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C26H25N7O
|
1
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| 1 |
IC50 = 862 nM
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CP0409463
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3-(4-imidazol-1-ylbutoxy)-4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazole
Show/Hide
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C15H21N5OS
|
4
|
| 1 |
IC50 = 870.96 nM
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|
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| 2 |
IC50 = 2290.87 nM
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| 3 |
IC50 = 52480.75 nM
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| 4 |
IC50 = 53703.18 nM
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CP0391917
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propan-2-yl 4-[[(2S)-1-[4-[1-[(4-chlorophenyl)methyl]pyrrolidin-1-ium-1-yl]piperidin-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C36H44ClN4O5+
|
1
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| 1 |
IC50 = 881.5 nM
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CP0859752
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid ethyl ester oxalic acid
Show/Hide
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C18H23NO6
|
1
|
| 1 |
IC50 = 888.1 nM
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CP0855705
|
1-Ethyl-3-(3-pentyl-[1,2,4]oxadiazol-5-yl)-4-phenyl-1,2,3,6-tetrahydro-pyridine oxalic acid
Show/Hide
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C22H29N3O5
|
1
|
| 1 |
IC50 = 888.6 nM
|
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CP0423465
|
propan-2-yl 4-[[(2S)-1-[4-[(4-chlorophenyl)methyl]-4-propan-2-ylpiperazin-4-ium-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C34H42ClN4O5+
|
1
|
| 1 |
IC50 = 893.5 nM
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|
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CP0860591
|
(3S,4R)-1-Ethyl-4-phenyl-piperidine-3-carboxylic acid cyclohexyl ester oxalic acid
Show/Hide
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C22H31NO6
|
1
|
| 1 |
IC50 = 913.1 nM
|
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CP0423458
|
2-[[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]ethyl-methyl-bis(naphthalen-2-ylmethyl)azanium
Show/Hide
|
C45H47N4O5+
|
1
|
| 1 |
IC50 = 948.4 nM
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CP0513680
|
3-but-2-ynyl-2-(1,4-diazepan-1-yl)-5-[(4-methylquinazolin-2-yl)methyl]imidazo[4,5-d]pyridazin-4-one
Show/Hide
|
C24H26N8O
|
1
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| 1 |
IC50 = 954 nM
|
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CP0880203
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 3-cyclohexyl-propyl ester oxalic acid
Show/Hide
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C25H35NO6
|
1
|
| 1 |
IC50 = 963.2 nM
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CP0505175
|
2-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]ethanamine
Show/Hide
|
C10H16N4OS
|
1
|
| 1 |
IC50 = 1000 nM
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|
|
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CP0388598
|
ethyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[(3S)-1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C30H34N4O6
|
1
|
| 1 |
IC50 = 1000 nM
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|
|
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CP0398626
|
propan-2-yl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C31H36N4O6
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
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CP0417386
|
ethyl 4-[[(2S)-1-[[1-(1,3-benzodioxol-5-ylmethyl)pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C31H34N4O7
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
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CP0422304
|
cyclopropylmethyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C32H36N4O6
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0474371
|
methyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C29H32N4O6
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0481463
|
propyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C31H36N4O6
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0493290
|
ethyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[1-[(2-methoxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C31H36N4O6
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0846158
|
N-{3-[(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenylpropyl}-N'-(phenylmethyl)urea
Show/Hide
|
C31H37N3O
|
1
|
| 1 |
IC50 = 1017 nM
|
|
|
|
CP0082776
|
1-[(4-methoxyphenyl)methyl]-N-[4-[(7-methoxy-1,2,3,4-tetrahydroacridin-9-yl)amino]butyl]-4-oxoquinoline-3-carboxamide
Show/Hide
|
C36H38N4O4
|
1
|
| 1 |
IC50 = 1070 nM
|
|
|
|
CP0462541
|
2-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]ethanol
Show/Hide
|
C10H15N3O2S
|
1
|
| 1 |
IC50 = 1071.52 nM
|
|
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CP0862779
|
1-Ethyl-5-(3-pentyl-[1,2,4]oxadiazol-5-yl)-4-phenyl-1,2,3,6-tetrahydro-pyridine oxalic acid
Show/Hide
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C22H29N3O5
|
1
|
| 1 |
IC50 = 1087.7 nM
|
|
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CP0378489
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-((E)-3-methyl-5-phenyl-pent-2-en-4-ynyl)-oxime
Show/Hide
|
C18H20N2O
|
1
|
| 1 |
IC50 = 1090 nM
|
|
|
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CP0512084
|
N-[3-[4-(5-bromopyridin-2-yl)piperazin-1-yl]-3-oxopropyl]-2,1,3-benzoxadiazole-4-sulfonamide
Show/Hide
|
C18H19BrN6O4S
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
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CP0454734
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-cyclobutyl-oxime
Show/Hide
|
C10H16N2O
|
1
|
| 1 |
IC50 = 1110 nM
|
|
|
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CP0430238
|
(4-chlorophenyl)methyl-[(3S)-1-[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]piperidin-3-yl]-dimethylazanium
Show/Hide
|
C34H42ClN4O5+
|
1
|
| 1 |
IC50 = 1115.3 nM
|
|
|
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CP0378490
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(2-chloro-phenyl)-prop-2-ynyl]-oxime
Show/Hide
|
C15H15ClN2O
|
1
|
| 1 |
IC50 = 1120 nM
|
|
|
|
CP0427980
|
8-((S)-3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(2-oxo-2-phenyl-ethyl)-3,7-dihydro-purine-2,6-dione
Show/Hide
|
C23H26N6O3
|
1
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| 1 |
IC50 = 1129 nM
|
|
|
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CP0393182
|
(3R,4R)-1-Ethyl-4-phenyl-piperidine-3-carboxylic acid cyclohexyl ester
Show/Hide
|
C20H29NO2
|
1
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| 1 |
IC50 = 1141.1 nM
|
|
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CP0285875
|
(R)-2-(2-(2-(8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-3-methyl-2,6-dioxo-2,3-dihydro-6H-purin-1(7H)-yl)acetyl)phenoxy)-N-methylacetamide
Show/Hide
|
C26H31N7O5
|
1
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| 1 |
IC50 = 1174 nM
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CP0202500
|
2-[(3R)-3-aminopiperidin-1-yl]-3-but-2-ynyl-5-[(4-methylquinazolin-2-yl)methyl]imidazo[4,5-d]pyridazin-4-one
Show/Hide
|
C24H26N8O
|
1
|
| 1 |
IC50 = 1190 nM
|
|
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|
CP0913099
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 3-methoxybenzyl(phenyl)carbamate
Show/Hide
|
C23H28N2O3
|
1
|
| 1 |
IC50 = 1206.8 nM
|
|
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CP0687661
|
3-[(3-Bromo-isoxazol-5-ylmethoxyimino)-methyl]-1-azonia-bicyclo[2.2.2]octane chloride
Show/Hide
|
C12H17BrClN3O2
|
2
|
| 1 |
IC50 = 1217 nM
|
|
|
| 2 |
IC50 = 8400 nM
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CP0397734
|
3-[1-{3-[3,4-Bis-(4-methoxy-benzyloxy)-phenyl]-isoxazol-5-yl}-meth-(E)-ylidene]-1-aza-bicyclo[2.2.1]heptane
Show/Hide
|
C32H32N2O5
|
1
|
| 1 |
IC50 = 1228 nM
|
|
|
|
CP0493289
|
ethyl 4-[[(2S)-1-[[1-[(3-chlorophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C30H33ClN4O5
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
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CP0894395
|
(3S)-3-((S)-3-(4-aminophenyl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-1-methylpyrrolidinium
Show/Hide
|
C32H38IN5O6
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0875271
|
N-Ethyl-N'-{3-[(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenylpropyl}urea
Show/Hide
|
C26H35N3O
|
1
|
| 1 |
IC50 = 1276 nM
|
|
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|
CP0249049
|
3-[4-(2-chlorophenyl)sulfonylpiperazin-1-yl]-6-[(2S)-2-methylpiperidin-1-yl]pyridazine
Show/Hide
|
C20H26ClN5O2S
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
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CP0395561
|
propan-2-yl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[4-methyl-4-(2-phenylethyl)piperazin-4-ium-1-yl]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C33H41N4O5+
|
1
|
| 1 |
IC50 = 1352.3 nM
|
|
|
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CP0219061
|
1-[(4-methoxyphenyl)methyl]-N-[5-[(7-methoxy-1,2,3,4-tetrahydroacridin-9-yl)amino]pentyl]-4-oxoquinoline-3-carboxamide
Show/Hide
|
C37H40N4O4
|
1
|
| 1 |
IC50 = 1370 nM
|
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|
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CP0854412
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 2-bromobenzyl(phenyl)carbamate
Show/Hide
|
C22H25BrN2O2
|
1
|
| 1 |
IC50 = 1394 nM
|
|
|
|
CP0212171
|
1-(2-Bromo benzenesulfonyl)-5-(4-ethylpiperazin-1-yl-methyl)-1H-indole
Show/Hide
|
C21H24BrN3O2S
|
1
|
| 1 |
IC50 = 1425 nM
|
|
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CP0447892
|
(4-chlorophenyl)methyl-[2-[[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]ethyl]-dimethylazanium
Show/Hide
|
C31H38ClN4O5+
|
1
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| 1 |
IC50 = 1429.2 nM
|
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CP0564233
|
1-[(4-methoxyphenyl)methyl]-4-oxo-N-[5-(1,2,3,4-tetrahydroacridin-9-ylamino)pentyl]quinoline-3-carboxamide
Show/Hide
|
C36H38N4O3
|
1
|
| 1 |
IC50 = 1480 nM
|
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CP0165027
|
1-[(4-methoxyphenyl)methyl]-4-oxo-N-[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]quinoline-3-carboxamide
Show/Hide
|
C37H40N4O3
|
1
|
| 1 |
IC50 = 1490 nM
|
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CP0404732
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-((Z)-3-methyl-pent-2-en-4-ynyl)-oxime
Show/Hide
|
C12H16N2O
|
1
|
| 1 |
IC50 = 1580 nM
|
|
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CP0555538
|
1-[(4-methoxyphenyl)methyl]-4-oxo-N-[4-(1,2,3,4-tetrahydroacridin-9-ylamino)butyl]quinoline-3-carboxamide
Show/Hide
|
C35H36N4O3
|
1
|
| 1 |
IC50 = 1590 nM
|
|
|
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CP0875270
|
N-{3-[(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenylpropyl}methanesulfonamide
Show/Hide
|
C24H32N2O2S
|
1
|
| 1 |
IC50 = 1597 nM
|
|
|
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CP0391224
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-(3-thiophen-2-yl-prop-2-ynyl)-oxime
Show/Hide
|
C13H14N2OS
|
1
|
| 1 |
IC50 = 1620 nM
|
|
|
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CP0915295
|
3-[(3-Methoxy-isoxazol-5-ylmethoxyimino)-methyl]-1-azonia-bicyclo[2.2.2]octane chloride
Show/Hide
|
C13H20ClN3O3
|
2
|
| 1 |
IC50 = 1641 nM
|
|
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| 2 |
IC50 = 29500 nM
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CP0376534
|
1-Methyl-5-(4-methylsulfanyl-[1,2,5]thiadiazol-3-yl)-1,2,3,6-tetrahydro-pyridine; oxalic acid
Show/Hide
|
C9H13N3S2
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
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CP0846965
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid phenyl ester oxalic acid
Show/Hide
|
C22H23NO6
|
1
|
| 1 |
IC50 = 1819.5 nM
|
|
|
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CP0902683
|
3-[(3-Cyano-isoxazol-5-ylmethoxyimino)-methyl]-1-azonia-bicyclo[2.2.1]heptane chloride
Show/Hide
|
C12H15ClN4O2
|
1
|
| 1 |
IC50 = 1860 nM
|
|
|
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CP0452476
|
(4-chlorophenyl)methyl-[(3R)-1-[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]piperidin-3-yl]-dimethylazanium
Show/Hide
|
C34H42ClN4O5+
|
1
|
| 1 |
IC50 = 1895.6 nM
|
|
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CP0516466
|
5-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]pentan-1-amine
Show/Hide
|
C13H22N4OS
|
2
|
| 1 |
IC50 = 1905.46 nM
|
|
|
| 2 |
IC50 = 44668.36 nM
|
|
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CP0861084
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 2-(4-methoxy-phenyl)-ethyl ester oxalic acid
Show/Hide
|
C25H29NO7
|
1
|
| 1 |
IC50 = 1941 nM
|
|
|
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CP0453286
|
2-Methyl-9-phenoxy-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
|
C28H26N2O4
|
1
|
| 1 |
IC50 = 1959.3 nM
|
|
|
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CP0383656
|
9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid propyl ester
Show/Hide
|
C24H26N2O4
|
1
|
| 1 |
IC50 = 1961.9 nM
|
|
|
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CP0844752
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 3-bromobenzyl(phenyl)carbamate
Show/Hide
|
C22H25BrN2O2
|
1
|
| 1 |
IC50 = 1964.3 nM
|
|
|
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CP0440679
|
ethyl 4-[[(2S)-1-[(1-benzylpyrrolidin-3-yl)amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C30H34N4O5
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
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CP0858376
|
Ethyl 4-[({[(1S)-1-[(4-hydroxyphenyl)methyl]-2-({1-[(4-hydroxyphenyl)methyl]-3-pyrrolidinyl}amino)-2-oxoethyl]amino}carbonyl)amino]benzoate
Show/Hide
|
C30H34N4O6
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
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CP0914880
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(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-3-(2-chlorophenyl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-methylpyrrolidinium
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C32H36ClIN4O6
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1
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| 1 |
IC50 = 1995.26 nM
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CP0522028
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N-[3-[4-(3-methylpyridin-4-yl)piperazin-1-yl]-3-oxopropyl]-2,1,3-benzothiadiazole-4-sulfonamide
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C19H22N6O3S2
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1
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| 1 |
IC50 = 2000 nM
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CP0238685
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1-[(4-methoxyphenyl)methyl]-4-oxo-N-[8-(1,2,3,4-tetrahydroacridin-9-ylamino)octyl]quinoline-3-carboxamide
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C39H44N4O3
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1
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| 1 |
IC50 = 2050 nM
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CP0393532
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N-[3-[4-(5-bromopyridin-2-yl)piperazin-1-yl]-3-oxopropyl]quinoline-5-sulfonamide
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C21H22BrN5O3S
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1
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| 1 |
IC50 = 2100 nM
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CP0082777
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1-[(4-methoxyphenyl)methyl]-4-oxo-N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]quinoline-3-carboxamide
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C38H42N4O3
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1
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| 1 |
IC50 = 2140 nM
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CP0920244
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N-{3-[(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenylpropyl}acetamide
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C25H32N2O
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1
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| 1 |
IC50 = 2198 nM
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CP0850116
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid ethyl ester oxalic acid
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C18H23NO6
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1
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| 1 |
IC50 = 2220.1 nM
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CP0860435
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid methyl ester oxalic acid
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C17H21NO6
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1
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| 1 |
IC50 = 2308.4 nM
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CP0478523
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1-[(4-methoxyphenyl)methyl]-N-[3-[(7-methoxy-1,2,3,4-tetrahydroacridin-9-yl)amino]propyl]-4-oxoquinoline-3-carboxamide
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C35H36N4O4
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1
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| 1 |
IC50 = 2480 nM
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CP0395563
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propan-2-yl 4-[[(2S)-1-[4-(cyclohexylmethyl)-4-methylpiperazin-4-ium-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
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C32H45N4O5+
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1
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| 1 |
IC50 = 2497.4 nM
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CP0503049
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ethyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[1-[(3-methoxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
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C31H36N4O6
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1
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| 1 |
IC50 = 2511.89 nM
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CP0372937
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1-Aza-bicyclo[2.2.1]heptan-3-one O-((E)-3-methyl-pent-2-en-4-ynyl)-oxime
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C12H16N2O
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1
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| 1 |
IC50 = 2590 nM
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CP0398368
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N-[3-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)propyl]-2,1,3-benzoxadiazole-4-sulfonamide
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C18H20N6O4S
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1
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| 1 |
IC50 = 2600 nM
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CP0438420
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1-Aza-bicyclo[2.2.1]heptan-3-one O-isopropyl-oxime
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C9H16N2O
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1
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| 1 |
IC50 = 2610 nM
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CP0513252
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N-[6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl]-1-[(4-methoxyphenyl)methyl]-4-oxoquinoline-3-carboxamide
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C37H39ClN4O3
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1
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| 1 |
IC50 = 2780 nM
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CP0437323
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3-but-2-ynyl-5-[(4-methylquinazolin-2-yl)methyl]-2-piperazin-1-ylimidazo[4,5-d]pyridazin-4-one
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C23H24N8O
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1
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| 1 |
IC50 = 2804 nM
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CP0854016
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 2,2-diphenyl-ethyl ester oxalic acid
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C30H31NO6
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1
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| 1 |
IC50 = 2829.7 nM
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CP0077503
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N-[5-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]pentyl]-1-[(4-methoxyphenyl)methyl]-4-oxoquinoline-3-carboxamide
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C36H37ClN4O3
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1
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| 1 |
IC50 = 3270 nM
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CP0451231
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2,9-Dimethyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
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C23H24N2O3
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1
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| 1 |
IC50 = 3277.5 nM
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CP0880188
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(3R,4R)-1-Ethyl-4-phenyl-piperidine-3-carboxylic acid phenethyl ester oxalic acid
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C24H29NO6
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1
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| 1 |
IC50 = 3285.2 nM
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CP0399788
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1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(3-chloro-phenyl)-prop-2-ynyl]-oxime
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C15H15ClN2O
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1
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| 1 |
IC50 = 3340 nM
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CP0374606
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1-Aza-bicyclo[2.2.1]heptan-3-one O-(1-methyl-prop-2-ynyl)-oxime
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C10H14N2O
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1
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| 1 |
IC50 = 3690 nM
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CP0061477
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7-methoxytacrine
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C14H16N2O
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1
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| 1 |
IC50 = 3710 nM
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CP0077515
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1-[(4-methoxyphenyl)methyl]-N-[2-[(7-methoxy-1,2,3,4-tetrahydroacridin-9-yl)amino]ethyl]-4-oxoquinoline-3-carboxamide
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C34H34N4O4
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1
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| 1 |
IC50 = 3710 nM
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CP0408846
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9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid methyl ester
Show/Hide
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C22H22N2O4
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1
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| 1 |
IC50 = 3788 nM
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CP0467741
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3-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-1-ol
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C11H17N3O2S
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1
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| 1 |
IC50 = 3801.89 nM
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CP0858937
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endo-1-(3-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)-2,2-diphenylpropyl)urea
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C24H31N3O
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1
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| 1 |
IC50 = 3829 nM
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CP0470396
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1-Aza-bicyclo[2.2.1]heptan-3-one O-tert-butyl-oxime
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C10H18N2O
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1
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| 1 |
IC50 = 3840 nM
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CP0468406
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ethyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[(3R)-1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
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C30H34N4O6
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1
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| 1 |
IC50 = 3981.07 nM
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CP0305211
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1-(1'-(2-methylbenzyl)-1,4'-bipiperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
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C25H32N4O
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1
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| 1 |
IC50 = 3981.07 nM
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CP0404826
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1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(4-chloro-phenyl)-prop-2-ynyl]-oxime
Show/Hide
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C15H15ClN2O
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1
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| 1 |
IC50 = 4010 nM
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CP0159140
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N-[3-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]propyl]-1-[(4-methoxyphenyl)methyl]-4-oxoquinoline-3-carboxamide
Show/Hide
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C34H33ClN4O3
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1
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| 1 |
IC50 = 4010 nM
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CP0886217
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 2,2-diphenyl-ethyl ester oxalic acid
Show/Hide
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C30H31NO6
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1
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| 1 |
IC50 = 4024.4 nM
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CP0372924
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1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(2-fluoro-phenyl)-prop-2-ynyl]-oxime
Show/Hide
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C15H15FN2O
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1
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| 1 |
IC50 = 4030 nM
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CP0407773
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1-Aza-bicyclo[2.2.1]heptan-3-one O-allyl-oxime
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C9H14N2O
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1
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| 1 |
IC50 = 4050 nM
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CP0404668
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9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid isopropyl ester
Show/Hide
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C24H26N2O4
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1
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| 1 |
IC50 = 4058 nM
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CP0077505
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N-[4-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]butyl]-1-[(4-methoxyphenyl)methyl]-4-oxoquinoline-3-carboxamide
Show/Hide
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C35H35ClN4O3
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1
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| 1 |
IC50 = 4110 nM
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CP0077507
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N-[2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]ethyl]-1-[(4-methoxyphenyl)methyl]-4-oxoquinoline-3-carboxamide
Show/Hide
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C33H31ClN4O3
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1
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| 1 |
IC50 = 4230 nM
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CP0448197
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9-Ethoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
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C24H26N2O4
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1
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| 1 |
IC50 = 4250 nM
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CP0522031
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N-[3-[4-(4-chloropyridin-2-yl)piperazin-1-yl]-3-oxopropyl]-2,1,3-benzothiadiazole-4-sulfonamide
Show/Hide
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C18H19ClN6O3S2
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1
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| 1 |
IC50 = 4500 nM
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CP0527221
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N-[3-[4-(5-bromopyridin-2-yl)piperazin-1-yl]-3-oxopropyl]-7-fluoro-2,1,3-benzoxadiazole-4-sulfonamide
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C18H18BrFN6O4S
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1
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| 1 |
IC50 = 4800 nM
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CP0392492
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1-Aza-bicyclo[2.2.1]heptan-3-one O-(3-thiophen-3-yl-prop-2-ynyl)-oxime
Show/Hide
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C13H14N2OS
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1
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| 1 |
IC50 = 4840 nM
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CP0510618
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2-Methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
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C22H22N2O3
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1
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| 1 |
IC50 = 5009.3 nM
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CP0165028
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N-[7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl]-1-[(4-methoxyphenyl)methyl]-4-oxoquinoline-3-carboxamide
Show/Hide
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C38H41ClN4O3
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1
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| 1 |
IC50 = 5350 nM
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CP0392405
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1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(4-fluoro-phenyl)-prop-2-ynyl]-oxime
Show/Hide
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C15H15FN2O
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1
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| 1 |
IC50 = 5460 nM
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CP0893472
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2-(3-Amino-piperidin-1-yl)-3-but-2-ynyl-5-dibenzo[b,f][1,4]oxazepin-11-ylmethyl-3,5-dihydro-imidazo[4,5-d]pyridazin-4-one
Show/Hide
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C28H27N7O2
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1
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| 1 |
IC50 = 5607 nM
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CP0448414
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9-Methoxy-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
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C22H22N2O4
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1
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| 1 |
IC50 = 5616.8 nM
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CP0049496
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6-chloro-1,2,3,4-tetrahydroacridin-9-amine
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C13H13ClN2
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1
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| 1 |
IC50 = 6090 nM
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CP0500468
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2,7-Dimethyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
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C23H24N2O3
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1
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| 1 |
IC50 = 6109.7 nM
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CP0435251
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8-((R)-3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(2-oxo-2-phenyl-ethyl)-3,7-dihydro-purine-2,6-dione
Show/Hide
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C23H26N6O3
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1
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| 1 |
IC50 = 6161 nM
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CP0294233
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4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-phthalazin-1-one
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C22H24ClN3O
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1
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| 1 |
IC50 = 6309.57 nM
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CP0139207
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9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
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C23H24N2O4
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2
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| 1 |
IC50 = 6558.7 nM
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| 2 |
Ki = 1318.26 nM
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CP0510872
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N-methyl-4-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]butan-1-amine
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C13H22N4OS
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1
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| 1 |
IC50 = 7079.46 nM
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CP0448496
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2-Methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid methyl ester
Show/Hide
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C21H20N2O3
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1
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| 1 |
IC50 = 7121.2 nM
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CP0382879
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1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(3-methoxy-phenyl)-prop-2-ynyl]-oxime
Show/Hide
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C16H18N2O2
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1
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| 1 |
IC50 = 7680 nM
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CP0314376
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1-[(4-methoxyphenyl)methyl]-N-[8-[(7-methoxy-1,2,3,4-tetrahydroacridin-9-yl)amino]octyl]-4-oxoquinoline-3-carboxamide
Show/Hide
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C40H46N4O4
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1
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| 1 |
IC50 = 7860 nM
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CP0511644
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1-Aza-bicyclo[2.2.1]heptan-3-one O-hept-2-ynyl-oxime
Show/Hide
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C13H20N2O
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1
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| 1 |
IC50 = 7890 nM
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CP0404049
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8,9-Dimethoxy-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
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C23H24N2O5
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1
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| 1 |
IC50 = 8221.3 nM
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CP0241945
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1-[(4-methoxyphenyl)methyl]-N-[6-[(7-methoxy-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl]-4-oxoquinoline-3-carboxamide
Show/Hide
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C38H42N4O4
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1
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| 1 |
IC50 = 8610 nM
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CP0454447
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8-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
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C23H24N2O4
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1
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| 1 |
IC50 = 9017.8 nM
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CP0422252
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1-Aza-bicyclo[2.2.1]heptan-3-one O-hex-5-en-2-ynyl-oxime
Show/Hide
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C12H16N2O
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1
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| 1 |
IC50 = 9440 nM
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CP0241967
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N-[8-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]octyl]-1-[(4-methoxyphenyl)methyl]-4-oxoquinoline-3-carboxamide
Show/Hide
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C39H43ClN4O3
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1
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| 1 |
IC50 = 9450 nM
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CP0454771
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1-Aza-bicyclo[2.2.1]heptan-3-one O-hex-2-ynyl-oxime
Show/Hide
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C12H18N2O
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1
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| 1 |
IC50 = 9640 nM
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CP0461117
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1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(3-fluoro-phenyl)-prop-2-ynyl]-oxime
Show/Hide
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C15H15FN2O
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1
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| 1 |
IC50 = 9850 nM
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CP0795225
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1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylaminocarbonyl)oxime
Show/Hide
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C19H16N2O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0170456
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3-chloro-1-(4-fluoro benzenesulfonyl)-5-(4-methylpiperazin-1-yl-methyl)-1H-indole
Show/Hide
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C20H21ClFN3O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0159968
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N-[3-oxo-3-(4-pyridin-2-ylpiperazin-1-yl)propyl]-2,1,3-benzothiadiazole-4-sulfonamide
Show/Hide
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C18H20N6O3S2
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1
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| 1 |
IC50 > 10000 nM
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CP0393535
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N-[3-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)propyl]pyridine-3-sulfonamide
Show/Hide
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C17H21N5O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0398367
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N-[3-[4-(6-fluoropyridin-2-yl)piperazin-1-yl]-3-oxopropyl]-2,1,3-benzothiadiazole-4-sulfonamide
Show/Hide
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C18H19FN6O3S2
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1
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| 1 |
IC50 > 10000 nM
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CP0425875
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N-[3-[4-(2-fluoropyridin-4-yl)piperazin-1-yl]-3-oxopropyl]-2,1,3-benzothiadiazole-4-sulfonamide
Show/Hide
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C18H19FN6O3S2
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1
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| 1 |
IC50 > 10000 nM
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CP0425876
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5-methyl-N-[3-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)propyl]-2,1,3-benzoxadiazole-4-sulfonamide
Show/Hide
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C19H22N6O4S
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1
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| 1 |
IC50 > 10000 nM
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CP0425877
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N-[3-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)propyl]-1,3-benzothiazole-4-sulfonamide
Show/Hide
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C19H21N5O3S2
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1
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| 1 |
IC50 > 10000 nM
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CP0438318
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N-[3-[4-(6-chloropyridin-2-yl)piperazin-1-yl]-3-oxopropyl]-2,1,3-benzothiadiazole-4-sulfonamide
Show/Hide
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C18H19ClN6O3S2
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1
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| 1 |
IC50 > 10000 nM
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CP0456282
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N-[3-[4-(5-bromopyridin-2-yl)piperazin-1-yl]-3-oxopropyl]-5-chloro-2,1,3-benzoxadiazole-4-sulfonamide
Show/Hide
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C18H18BrClN6O4S
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1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0457506
|
N-[3-[4-(5-bromopyridin-2-yl)piperazin-1-yl]-3-oxopropyl]naphthalene-1-sulfonamide
Show/Hide
|
C22H23BrN4O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0458294
|
N-[3-[4-(5-chloropyrimidin-2-yl)piperazin-1-yl]-3-oxopropyl]-2,1,3-benzothiadiazole-4-sulfonamide
Show/Hide
|
C17H18ClN7O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0463031
|
N-[3-(4-pyridin-4-ylpiperazin-1-yl)propyl]-2,1,3-benzothiadiazole-4-sulfonamide
Show/Hide
|
C18H22N6O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0512085
|
N-[3-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)propyl]-2,1,3-benzothiadiazole-5-sulfonamide
Show/Hide
|
C18H20N6O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0522029
|
N-[3-[4-(2-chloropyridin-4-yl)piperazin-1-yl]-3-oxopropyl]-2,1,3-benzothiadiazole-4-sulfonamide
Show/Hide
|
C18H19ClN6O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0522033
|
N-[3-oxo-3-(4-pyrimidin-2-ylpiperazin-1-yl)propyl]-2,1,3-benzothiadiazole-4-sulfonamide
Show/Hide
|
C17H19N7O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0522035
|
N-[3-[4-(1,3-benzothiazol-2-yl)piperazin-1-yl]-3-oxopropyl]-2,1,3-benzothiadiazole-4-sulfonamide
Show/Hide
|
C20H20N6O3S3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0522036
|
N-[3-[4-(5-bromopyridin-2-yl)piperazin-1-yl]-3-oxopropyl]-5-methyl-2,1,3-benzoxadiazole-4-sulfonamide
Show/Hide
|
C19H21BrN6O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0522037
|
N-[3-[4-(5-bromopyridin-2-yl)piperazin-1-yl]-3-oxopropyl]quinoline-8-sulfonamide
Show/Hide
|
C21H22BrN5O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0522038
|
N-[3-[4-(5-bromopyridin-2-yl)piperazin-1-yl]-3-oxopropyl]-3-methoxybenzenesulfonamide
Show/Hide
|
C19H23BrN4O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0522040
|
N-[3-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)propyl]-3-(tetrazol-1-yl)benzenesulfonamide
Show/Hide
|
C19H22N8O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0524905
|
N-[3-[4-(1,3-benzoxazol-2-yl)piperazin-1-yl]-3-oxopropyl]-2,1,3-benzothiadiazole-4-sulfonamide
Show/Hide
|
C20H20N6O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0524906
|
5-methyl-N-[3-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)propyl]-2,1,3-benzothiadiazole-4-sulfonamide
Show/Hide
|
C19H22N6O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0524907
|
5-(dimethylamino)-N-[3-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)propyl]naphthalene-1-sulfonamide
Show/Hide
|
C24H29N5O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0524908
|
N-methyl-N-[3-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)propyl]-2,1,3-benzothiadiazole-4-sulfonamide
Show/Hide
|
C19H22N6O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0527220
|
N-[3-[4-(6-methylpyridin-2-yl)piperazin-1-yl]-3-oxopropyl]-2,1,3-benzothiadiazole-4-sulfonamide
Show/Hide
|
C19H22N6O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0527609
|
N-[3-[4-(4-methylpyridin-2-yl)piperazin-1-yl]-3-oxopropyl]-2,1,3-benzothiadiazole-4-sulfonamide
Show/Hide
|
C19H22N6O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0527610
|
N-[5-[[3-[4-(5-bromopyridin-2-yl)piperazin-1-yl]-3-oxopropyl]sulfamoyl]-4-methyl-1,3-thiazol-2-yl]acetamide
Show/Hide
|
C18H23BrN6O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0531368
|
N-[3-oxo-3-[4-(1,3-thiazol-2-yl)piperazin-1-yl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide
Show/Hide
|
C16H18N6O3S3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0410767
|
(4-pyridin-4-ylpiperazin-1-yl)-[1-[6-(trifluoromethyl)pyridin-3-yl]sulfonylazetidin-3-yl]methanone
Show/Hide
|
C19H20F3N5O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0412565
|
[1-(5-chloropyridin-2-yl)sulfonylazetidin-3-yl]-(4-pyridin-4-ylpiperazin-1-yl)methanone
Show/Hide
|
C18H20ClN5O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0412566
|
[1-(1H-indazol-6-ylsulfonyl)azetidin-3-yl]-(4-pyridin-4-ylpiperazin-1-yl)methanone
Show/Hide
|
C20H22N6O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0412567
|
[1-(6-methoxypyridin-3-yl)sulfonylazetidin-3-yl]-(4-pyridin-4-ylpiperazin-1-yl)methanone
Show/Hide
|
C19H23N5O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0412602
|
[1-(2,1,3-benzothiadiazol-4-ylsulfonyl)piperidin-3-yl]-(4-pyridin-4-ylpiperazin-1-yl)methanone
Show/Hide
|
C21H24N6O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0428848
|
[1-(2,1,3-benzothiadiazol-4-ylsulfonyl)pyrrolidin-3-yl]-(4-pyridin-4-ylpiperazin-1-yl)methanone
Show/Hide
|
C20H22N6O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0432414
|
[1-(4-methylpyridin-2-yl)sulfonylazetidin-3-yl]-(4-pyridin-4-ylpiperazin-1-yl)methanone
Show/Hide
|
C19H23N5O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0526895
|
(2-pyridin-4-yl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl)-(1-quinolin-5-ylsulfonylazetidin-3-yl)methanone
Show/Hide
|
C24H25N5O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0564404
|
N-[4-[6-[[(2R)-6-(oxan-4-ylmethyl)-6-azaspiro[2.5]octan-2-yl]methylamino]pyridazin-3-yl]phenyl]acetamide
Show/Hide
|
C26H35N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0447292
|
(9bS)-9b-(4-chloro-3-methylphenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydroimidazo[2,1-a]isoindol-5-one
Show/Hide
|
C24H17ClF2N2O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0543500
|
1-(2,3-dihydro-1-benzofuran-5-ylsulfonyl)-4-[2-(1-methylimidazol-2-yl)ethynyl]piperidine
Show/Hide
|
C19H21N3O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0543504
|
1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(1-methylimidazol-2-yl)sulfanylmethyl]piperidine
Show/Hide
|
C18H23N3O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0543505
|
1-(1,3-benzodioxol-5-ylsulfonyl)-4-[(1-methylimidazol-2-yl)sulfanylmethyl]piperidine
Show/Hide
|
C17H21N3O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0545259
|
1-[(2-methyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]-4-[(1-methylimidazol-2-yl)sulfanylmethyl]piperidine
Show/Hide
|
C19H25N3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0550226
|
6-[4-[(1-methylimidazol-2-yl)sulfanylmethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
|
C19H22N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0550227
|
5-[(3-acetylphenoxy)methyl]-N-methyl-N-[(1S)-1-pyridin-2-ylethyl]-1,2-oxazole-3-carboxamide
Show/Hide
|
C21H21N3O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0551938
|
2-[[4-(2,3-dihydro-1-benzofuran-5-ylsulfonyl)cyclohexyl]methylsulfanyl]-1-methylimidazole
Show/Hide
|
C19H24N2O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0568216
|
1-(2,3-dihydro-1H-inden-5-ylsulfonyl)-4-[(1-methylimidazol-2-yl)sulfanylmethyl]piperidine
Show/Hide
|
C19H25N3O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0569321
|
6-[4-[(1-methylimidazol-2-yl)sulfanylmethyl]piperidin-1-yl]sulfonyl-1,3-benzothiazole
Show/Hide
|
C17H20N4O2S3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0571273
|
(2S,4S)-1-(2,3-dihydro-1-benzofuran-5-ylsulfonyl)-2-methyl-4-[(1-methylimidazol-2-yl)sulfanylmethyl]piperidine
Show/Hide
|
C19H25N3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0572852
|
(3aR,6aS)-2-(2,3-dihydro-1-benzofuran-5-ylsulfonyl)-5-(1-methylimidazol-2-yl)sulfanyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole
Show/Hide
|
C19H23N3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0576596
|
2-[2-[1-(2,3-dihydro-1-benzofuran-5-ylsulfonyl)piperidin-4-yl]ethyl]-1,3-thiazole
Show/Hide
|
C18H22N2O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0576600
|
1-(3,4-dihydro-2H-chromen-6-ylsulfonyl)-4-[(1-methylimidazol-2-yl)sulfanylmethyl]piperidine
Show/Hide
|
C19H25N3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0568251
|
N-(1,3-benzothiazol-5-yl)-1-(1,3-dimethylpyrazol-4-yl)sulfonylpiperidine-4-carboxamide
Show/Hide
|
C18H21N5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0568826
|
(3R,4R)-N-(1,3-benzothiazol-5-yl)-1-(1,3-dimethylpyrazol-4-yl)sulfonyl-3-fluoropiperidine-4-carboxamide
Show/Hide
|
C18H20FN5O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0464785
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(4-methoxy-phenyl)-prop-2-ynyl]-oxime
Show/Hide
|
C16H18N2O2
|
1
|
| 1 |
IC50 = 10600 nM
|
|
|
|
CP0403792
|
9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene
Show/Hide
|
C20H20N2O2
|
1
|
| 1 |
IC50 = 10766.6 nM
|
|
|
|
CP0077512
|
1-[(4-methoxyphenyl)methyl]-N-[7-[(7-methoxy-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl]-4-oxoquinoline-3-carboxamide
Show/Hide
|
C39H44N4O4
|
1
|
| 1 |
IC50 = 11400 nM
|
|
|
|
CP0474094
|
ethyl 4-[[(2R)-3-(4-hydroxyphenyl)-1-[[(3S)-1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C30H34N4O6
|
1
|
| 1 |
IC50 = 12589.25 nM
|
|
|
|
CP0458944
|
8,9-Dimethoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
|
C24H26N2O5
|
1
|
| 1 |
IC50 = 12903.4 nM
|
|
|
|
CP0001598
|
1,2,3,4-tetrahydro-9-acridinamine
Show/Hide
|
C13H14N2
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0392363
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-(3-p-tolyl-prop-2-ynyl)-oxime
Show/Hide
|
C16H18N2O
|
1
|
| 1 |
IC50 = 14100 nM
|
|
|
|
CP0470371
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-but-3-ynyl-oxime
Show/Hide
|
C10H14N2O
|
1
|
| 1 |
IC50 = 14450 nM
|
|
|
|
CP0847187
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(3-nitro-phenyl)-prop-2-ynyl]-oxime
Show/Hide
|
C15H15N3O3
|
1
|
| 1 |
IC50 = 15100 nM
|
|
|
|
CP0405578
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-[3-(2-methoxy-phenyl)-prop-2-ynyl]-oxime
Show/Hide
|
C16H18N2O2
|
1
|
| 1 |
IC50 = 16600 nM
|
|
|
|
CP0854472
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid phenyl ester oxalic acid
Show/Hide
|
C22H23NO6
|
1
|
| 1 |
IC50 = 19027.3 nM
|
|
|
|
CP0457637
|
ethyl 4-[[(2R)-3-(4-hydroxyphenyl)-1-[[(3R)-1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C30H34N4O6
|
1
|
| 1 |
IC50 = 19952.62 nM
|
|
|
|
CP0457513
|
8-Methyl-6,7,8,9-tetrahydro-5H-2,4-dithia-1,3,8-triaza-cyclopenta[a]naphthalene
Show/Hide
|
C9H11N3S2
|
1
|
| 1 |
IC50 = 20500 nM
|
|
|
|
CP0425291
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-methyl-oxime
Show/Hide
|
C7H12N2O
|
2
|
| 1 |
IC50 = 26900 nM
|
|
|
| 2 |
IC50 = 85050 nM
|
|
|
|
CP0287892
|
2-(2-bromophenoxy)-1-(2,4-dihydroxyphenyl)ethanone
Show/Hide
|
C14H11BrO4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0317131
|
(9bS)-9b-(4-chlorophenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydroimidazo[2,1-a]isoindol-5-one
Show/Hide
|
C23H15ClF2N2O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0381562
|
9b-(4-chlorophenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydroimidazo[2,1-a]isoindol-5-one
Show/Hide
|
C23H15ClF2N2O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0381587
|
1-(3,4-difluorobenzoyl)-9b-phenyl-2,3-dihydroimidazo[2,1-a]isoindol-5-one
Show/Hide
|
C23H16F2N2O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0381598
|
1-(4-fluorobenzoyl)-9b-phenyl-2,3-dihydroimidazo[2,1-a]isoindol-5-one
Show/Hide
|
C23H17FN2O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0448346
|
8,9-Dimethoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene
Show/Hide
|
C21H22N2O3
|
1
|
| 1 |
IC50 = 32653.5 nM
|
|
|
|
CP0847050
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid methyl ester oxalic acid
Show/Hide
|
C17H21NO6
|
1
|
| 1 |
IC50 = 33117.6 nM
|
|
|
|
CP0461482
|
1-Aza-bicyclo[2.2.1]heptan-3-one O-(4-methoxy-but-2-ynyl)-oxime
Show/Hide
|
C11H16N2O2
|
1
|
| 1 |
IC50 = 42400 nM
|
|
|
|
CP0436313
|
4-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]butan-1-amine
Show/Hide
|
C12H20N4OS
|
1
|
| 1 |
IC50 = 77624.71 nM
|
|
|
|
CP0382980
|
6,7,8,9-Tetrahydro-2-thia-1,3,8-triaza-cyclopenta[a]naphthalene
Show/Hide
|
C9H9N3S
|
1
|
| 1 |
IC50 = 100000 nM
|
|
|
|
CP0421075
|
1,4-Dimethyl-5-(4-methylsulfanyl-[1,2,5]thiadiazol-3-yl)-1,2,3,6-tetrahydro-pyridine
Show/Hide
|
C10H15N3S2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0878151
|
(4-{5-[1-Aza-bicyclo[2.2.2]oct-(3Z)-ylidenemethyl]-isoxazol-3-yl}-phenyl)-carbamic acid tert-butyl ester
Show/Hide
|
C22H27N3O3
|
1
|
| 1 |
IC50 > 10 nM
|
|
|
|
CP0218742
|
3,4-dihydro-1H-isoquinolin-2-yl-[1-[6-(4-ethylphenoxy)pyrimidin-4-yl]piperidin-4-yl]methanone
Show/Hide
|
C27H30N4O2
|
1
|
| 1 |
IC50 < 1500 nM
|
|
|
|
CP0398625
|
4-[[(2S)-1-[[1-[(4-cyanophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]-N-phenylbenzamide
Show/Hide
|
C35H34N6O4
|
1
|
| 1 |
IC50 > 3162.28 nM
|
|
|
|
CP0398628
|
2-methylpropyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C32H38N4O6
|
1
|
| 1 |
IC50 > 3162.28 nM
|
|
|
|
CP0417390
|
N-benzyl-4-[[(2S)-1-[[1-[(4-cyanophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzamide
Show/Hide
|
C36H36N6O4
|
1
|
| 1 |
IC50 > 3162.28 nM
|
|
|
|
CP0455901
|
4-[[(2S)-1-[[1-[(4-cyanophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]-N,N-diethylbenzamide
Show/Hide
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C33H38N6O4
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1
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| 1 |
IC50 > 3162.28 nM
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CP0455902
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4-[[(2S)-1-[[1-[(4-cyanophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]-N-methylbenzamide
Show/Hide
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C30H32N6O4
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1
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| 1 |
IC50 > 3162.28 nM
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CP0459567
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4-[[(2S)-1-[[1-[(4-cyanophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]-N-propan-2-ylbenzamide
Show/Hide
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C32H36N6O4
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1
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| 1 |
IC50 > 3162.28 nM
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CP0459569
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4-[[(2S)-1-[[1-[(4-cyanophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]-N-(cyclopropylmethyl)benzamide
Show/Hide
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C33H36N6O4
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1
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| 1 |
IC50 > 3162.28 nM
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CP0474370
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4-[[(2S)-1-[[1-[(4-cyanophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]-N-ethylbenzamide
Show/Hide
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C31H34N6O4
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1
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| 1 |
IC50 > 3162.28 nM
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CP0493286
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4-[[(2S)-1-[[1-[(4-cyanophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]-N-propylbenzamide
Show/Hide
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C32H36N6O4
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1
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| 1 |
IC50 > 3162.28 nM
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CP0493288
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ethyl 4-[[(2S)-1-[(1-ethylpyrrolidin-3-yl)amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
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C25H32N4O5
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1
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| 1 |
IC50 > 3162.28 nM
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CP0495636
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(2S)-N-[1-[(4-cyanophenyl)methyl]pyrrolidin-3-yl]-3-(4-hydroxyphenyl)-2-[[4-(morpholine-4-carbonyl)phenyl]carbamoylamino]propanamide
Show/Hide
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C33H36N6O5
|
1
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| 1 |
IC50 > 3162.28 nM
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CP0503050
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ethyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-oxo-1-[[1-[[3-(trifluoromethyl)phenyl]methyl]pyrrolidin-3-yl]amino]propan-2-yl]carbamoylamino]benzoate
Show/Hide
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C31H33F3N4O5
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1
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| 1 |
IC50 > 3162.28 nM
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CP0376700
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2-[[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]ethyl-methyl-di(propan-2-yl)azanium
Show/Hide
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C29H43N4O5+
|
1
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| 1 |
IC50 > 3300 nM
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CP0391916
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2-[benzyl-[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]ethyl-trimethylazanium
Show/Hide
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C32H41N4O5+
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1
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| 1 |
IC50 > 3300 nM
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CP0395558
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propan-2-yl 4-[[(2S)-1-[4-(1-ethylpyrrolidin-1-ium-1-yl)piperidin-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
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C31H43N4O5+
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1
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| 1 |
IC50 > 3300 nM
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CP0423461
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propan-2-yl 4-[[(2S)-1-[4-(1,3-benzodioxol-5-ylmethyl)-4-methylpiperazin-4-ium-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
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C33H39N4O7+
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1
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| 1 |
IC50 > 3300 nM
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CP0430242
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propan-2-yl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[2-(1-methylazepan-1-ium-1-yl)ethylamino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
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C29H41N4O5+
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1
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| 1 |
IC50 > 3300 nM
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CP0499982
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propan-2-yl 4-[[(2S)-1-[[1-[(4-chlorophenyl)methyl]-3-methylimidazol-3-ium-2-yl]methyl-methylamino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
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C33H37ClN5O5+
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1
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| 1 |
IC50 > 3300 nM
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CP0499983
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propan-2-yl 4-[[(2S)-1-[(1,3-dimethylimidazol-1-ium-2-yl)methyl-methylamino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
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C27H34N5O5+
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1
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| 1 |
IC50 > 3300 nM
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CP0437322
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2-(2-aminoethylamino)-3-but-2-ynyl-5-[(4-methylquinazolin-2-yl)methyl]imidazo[4,5-d]pyridazin-4-one
Show/Hide
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C21H22N8O
|
1
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| 1 |
IC50 > 5000 nM
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CP0437324
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2-[(3R)-3-aminopiperidin-1-yl]-5-(benzo[b][1,4]benzoxazepin-6-ylmethyl)-3-but-2-ynylimidazo[4,5-d]pyridazin-4-one
Show/Hide
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C28H27N7O2
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1
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| 1 |
IC50 > 5000 nM
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CP0513677
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2-[[(2S)-2-aminopropyl]amino]-3-but-2-ynyl-5-[(4-methylquinazolin-2-yl)methyl]imidazo[4,5-d]pyridazin-4-one
Show/Hide
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C22H24N8O
|
1
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| 1 |
IC50 > 5000 nM
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CP0507278
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3-(3-Methyl-isoxazol-5-ylmethylene)-1-aza-bicyclo[2.2.2]octane
Show/Hide
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C12H16N2O
|
1
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| 1 |
IC50 ~ 10000 nM
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CP0675682
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N-{(3S)-1-[(3-hydroxyphenyl)methyl]-1-methyl-3-piperidiniumyl}-N-{[(4-{[(1-methylethyl)oxy]carbonyl}phenyl)amino]carbonyl}-L-tyrosinamide
Show/Hide
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C33H41IN4O6
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3
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| 1 |
Kd = 0.1259 nM
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| 2 |
Kd = 15.85 nM
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| 3 |
Ki = 0.3162 nM
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CP0234914
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N-[[4-fluoro-3-[3-[[(3S)-3-methylpiperazin-1-yl]methyl]phenyl]phenyl]methyl]-3-(piperidin-4-ylmethyl)benzamide
Show/Hide
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C32H39FN4O
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2
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| 1 |
Kd = 0.1995 nM
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| 2 |
Kd = 2.512 nM
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CP0882700
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UMECLIDINIUM BROMIDE
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C29H34BrNO2
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2
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| 1 |
Kd = 0.3162 nM
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| 2 |
Ki = 0.16 nM
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CP0666822
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N-[({5-[(cyclohexyloxy)carbonyl]-2-thienyl}amino)carbonyl]-N-{[2-methyl-7-(2-naphthalenylmethyl)imidazo[2,1-b][1,3]thiazol-7-ium-6-yl]methyl}-L-tyrosinamide
Show/Hide
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C39H40IN5O5S2
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1
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| 1 |
Kd = 0.3162 nM
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CP0852183
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(S)-6-((3-(4-hydroxyphenyl)-2-(3-(4-(isopropoxycarbonyl)phenyl)ureido)propanamido)methyl)-2-methyl-7-(naphthalen-2-ylmethyl)-7H-imidazo[2,1-b]thiazol-4-ium 2,2,2-trifluoroacetate
Show/Hide
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C40H38F3N5O7S
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1
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| 1 |
Kd = 0.7943 nM
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CP0386412
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N-[[4-fluoro-3-[3-[[(3S)-3-methylpiperazin-1-yl]methyl]phenyl]phenyl]methyl]-3-(piperazin-1-ylmethyl)benzamide
Show/Hide
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C31H38FN5O
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1
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| 1 |
Kd = 1 nM
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CP0918663
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N-[(6-fluoro-3-{[(3S)-3-methyl-1-piperazinyl]methyl}-3-biphenylyl)methyl]-3-propanoyl benzamide
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C29H32FN3O2
|
1
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| 1 |
Kd = 1 nM
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CP0851222
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N-[(4-{[3-({[(6-fluoro-3'-{[(3S)-3-methyl-1-piperazinyl]methyl}-3-biphenylyl)methyl]amino} carbonyl)phenyl]methyl}-1,1-dimethylpiperazin-1-ium bistrifluoroacetate
Show/Hide
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C35H43F4N5O3
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1
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| 1 |
Kd = 1.995 nM
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CP0918664
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3-acetyl-N-[(6-fluoro-3-{[(3S)-3-methyl-1-piperazinyl]methyl}-3-biphenylyl)methyl] benzamide
Show/Hide
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C28H30FN3O2
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1
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| 1 |
Kd = 2.512 nM
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CP0922427
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(3S)-3-((S)-2-(3-(5-(cyclohexyloxycarbonyl)thiophen-2-yl)ureido)-3-(4-hydroxyphenyl)propanamido)-1-(4-hydroxybenzyl)-1-methylpiperidinium
Show/Hide
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C34H43IN4O6S
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1
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| 1 |
Kd = 2.512 nM
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CP0850322
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4-[Hydroxy(diphenyl)methyl]-1-[3-(phenyloxy)propyl]-1-azoniabicyclo[2.2.2]octane Bromide
Show/Hide
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C29H34BrNO2
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2
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| 1 |
Kd = 3.162 nM
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| 2 |
Ki = 0.64 nM
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CP0918662
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3-cyano-N-[(6-fluoro-3-{[(3S)-3-methyl-1-piperazinyl]methyl}-3-biphenylyl)methyl] benzamide
Show/Hide
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C27H27FN4O
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1
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| 1 |
Kd = 7.943 nM
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CP0891439
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(3S)-1-allyl-1-(3-hydroxybenzyl)-3-((S)-3-(4-hydroxyphenyl)-2-(3-(4-(isopropoxycarbonyl)phenyl)ureido)propanamido)piperidinium
Show/Hide
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C35H43IN4O6
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1
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| 1 |
Kd = 15.85 nM
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CP0904302
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(3S)-1-(4-hydroxybenzyl)-3-((S)-3-(4-hydroxyphenyl)-2-(3-(5-(isopropoxycarbonyl)thiophen-2-yl)ureido)propanamido)-1-methylpiperidinium
Show/Hide
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C31H39IN4O6S
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1
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| 1 |
Kd = 31.62 nM
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CP0894396
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(S)-1,1-bis(cyclopropylmethyl)-3-((S)-3-(4-hydroxyphenyl)-2-(3-(4-(isopropoxycarbonyl)phenyl)ureido)propanamido)piperidinium
Show/Hide
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C33H45IN4O5
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1
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| 1 |
Kd = 39.81 nM
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CP0869983
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(3S)-1-(4-hydroxybenzyl)-3-((S)-3-(4-hydroxyphenyl)-2-(3-(4-(isopropylcarbamoyl)phenyl)ureido)propanamido)-1-methylpiperidinium
Show/Hide
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C33H42IN5O5
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1
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| 1 |
Kd = 79.43 nM
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CP0880683
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(S)-2-((S)-3-(4-hydroxyphenyl)-2-(3-(4-(isopropoxycarbonyl)phenyl)ureido)propanamido)-6-azoniaspiro[5.6]dodecane
Show/Hide
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C31H43IN4O5
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1
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| 1 |
Kd = 79.43 nM
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CP0858368
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(3S)-1-(4-hydroxybenzyl)-3-((S)-3-(4-hydroxyphenyl)-2-(3-(4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl)ureido)propanamido)-1-methylpiperidinium
Show/Hide
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C32H37IN6O5
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1
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| 1 |
Kd = 125.89 nM
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CP0858377
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(3S)-1-(4-hydroxybenzyl)-3-((S)-3-(4-hydroxyphenyl)-2-(3-(4-(3-methyl-1,2,4-oxadiazol-5-yl)phenyl)ureido)propanamido)-1-methylpiperidinium
Show/Hide
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C32H37IN6O5
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1
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| 1 |
Kd = 158.49 nM
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CP0666404
|
Tiotropium bromide
Show/Hide
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C19H24BrNO5S2
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1
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| 1 |
Ki = 0.013 nM
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CP0199765
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5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide
Show/Hide
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C28H32N2O3
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1
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| 1 |
Ki = 0.115 nM
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CP0889526
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(S)-2-((2R,5S)-2-cyclohexyl-2-phenyl-[1,3]oxathiolan-5-yl)-1,1-dimethyl-pyrrolidinium iodide
Show/Hide
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C21H32INOS
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1
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| 1 |
Ki = 0.1175 nM
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CP0895932
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N-Endo-3-(2-cyano-2,2-diphenylethyl)-8-(hex-5-enyl)-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
Show/Hide
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C29H37BrN2
|
1
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| 1 |
Ki = 0.12 nM
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CP0109931
|
ATROPEN
Show/Hide
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C17H23NO3
|
2
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| 1 |
Ki = 0.25 nM
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| 2 |
Ki = 0.44 nM
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CP0877788
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(S)-2-((2S,5S)-2-cyclohexyl-2-phenyl-[1,3]oxathiolan-5-yl)-1,1-dimethyl-pyrrolidinium iodide
Show/Hide
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C21H32INOS
|
1
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| 1 |
Ki = 0.2512 nM
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CP0869209
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(S)-2-((S)-2,2-diphenyl-[1,3]oxathiolan-5-yl)-1,1-dimethyl-pyrrolidinium iodide
Show/Hide
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C21H26INOS
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1
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| 1 |
Ki = 0.2951 nM
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CP0858802
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(2R,2'S,5'R)-1-methyl-2-(2-cyclohexyl-2-phenyl-1,3-oxathiolan-5-yl)pirrolidine
Show/Hide
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C20H29NOS
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1
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| 1 |
Ki = 0.3467 nM
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CP0894658
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(3-endo)-3-(2,2-Di-2-thienylethenyl)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane Bromide
Show/Hide
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C19H24BrNS2
|
1
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| 1 |
Ki = 0.38 nM
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CP0070586
|
Ipratropium Bromide
Show/Hide
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C20H30BrNO3
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1
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| 1 |
Ki = 0.433 nM
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CP0881062
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(R)-2-((2R,5R)-2-cyclohexyl-2-phenyl-[1,3]oxathiolan-5-yl)-1,1-dimethyl-pyrrolidinium iodide
Show/Hide
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C21H32INOS
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1
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| 1 |
Ki = 0.5012 nM
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CP0858907
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(S)-(6,6-Diphenyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
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C20H26INO2
|
1
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| 1 |
Ki = 0.5012 nM
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CP0894757
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(R)-2-(5-((R)-cyclohexyl(hydroxy)(phenyl)methyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
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C23H32INO2
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1
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| 1 |
Ki = 0.6918 nM
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CP0877787
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(2R,5'R)-1-methyl2-(2,2-diphenyl-1,3-oxathiolan-5-yl)pirrolidine
Show/Hide
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C20H23NOS
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1
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| 1 |
Ki = 0.7586 nM
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CP0867620
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(+/-)-(6,6-Diphenyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
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C20H26INO2
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1
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| 1 |
Ki = 0.7943 nM
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CP0480832
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2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(3-methyl-benzyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
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C26H32F2N2O2
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1
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| 1 |
Ki = 0.88 nM
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CP0881063
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(2R,2'R,5'R)-1-methyl-2-(2-cyclohexyl-2-phenyl-1,3-oxathiolan-5-yl)pirrolidine
Show/Hide
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C20H29NOS
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1
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| 1 |
Ki = 0.912 nM
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CP0378654
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1-[3-[4-[7-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]heptyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C32H47N5O2S
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1
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| 1 |
Ki = 0.912 nM
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CP0881061
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(R)-2-((2S,5R)-2-cyclohexyl-2-phenyl-[1,3]oxathiolan-5-yl)-1,1-dimethyl-pyrrolidinium iodide
Show/Hide
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C21H32INOS
|
1
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| 1 |
Ki = 0.955 nM
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CP0409482
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(R)-1-(4-Amino-piperidin-1-yl)-2-cyclopentyl-2-hydroxy-2-phenyl-ethanone
Show/Hide
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C18H26N2O2
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1
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| 1 |
Ki = 0.98 nM
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CP0409513
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(R)-1-[4-(2-Amino-ethyl)-4-ethyl-piperidin-1-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
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C22H32F2N2O2
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1
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| 1 |
Ki = 1 nM
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CP0378646
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1-[3-[4-[9-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]nonyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C34H51N5O2S
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1
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| 1 |
Ki = 1.023 nM
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CP0871074
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(2R,5R)-2-cyclohexyl-2-phenyl-5-((dimethylamino)methyl)-1,3-oxathiolane methiodide
Show/Hide
|
C19H30INOS
|
1
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| 1 |
Ki = 1.096 nM
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CP0448091
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2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(3-hydroxy-benzyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
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C25H30F2N2O3
|
1
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| 1 |
Ki = 1.2 nM
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CP0405687
|
cyclohexyl-[5-(1-methylpyrrolidin-2-yl)furan-2-yl]-phenylmethanol
Show/Hide
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C22H29NO2
|
1
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| 1 |
Ki = 1.23 nM
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CP0439251
|
(R)-cyclohexyl-[5-[(2R)-1-methylpyrrolidin-2-yl]furan-2-yl]-phenylmethanol
Show/Hide
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C22H29NO2
|
1
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| 1 |
Ki = 1.23 nM
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CP0879684
|
(S)-(6,6-Diphenyl-1,4-dioxan-2-yl)-N,N-dimethylmethanamine Oxalate
Show/Hide
|
C21H25NO6
|
1
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| 1 |
Ki = 1.259 nM
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CP0498259
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(R)-1-[4-(2-Amino-ethylidene)-piperidin-1-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
|
C20H26F2N2O2
|
1
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| 1 |
Ki = 1.3 nM
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CP0858803
|
(2S,2'R,5'S)-1-methyl-2-(2-cyclohexyl-2-phenyl-1,3-oxathiolan-5-yl)pirrolidine
Show/Hide
|
C20H29NOS
|
1
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| 1 |
Ki = 1.38 nM
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CP0374993
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2-Cyclopentyl-2-hydroxy-N-[1-(3-methyl-benzyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
|
C26H34N2O2
|
1
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| 1 |
Ki = 1.4 nM
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CP0877786
|
(2S,2'S,5'S)-1-methyl-2-(2-cyclohexyl-2-phenyl-1,3-oxathiolan-5-yl)pirrolidine
Show/Hide
|
C20H29NOS
|
1
|
| 1 |
Ki = 1.479 nM
|
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CP0376761
|
(R)-N-[1-(6-Amino-pyridin-2-ylmethyl)-piperidin-4-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-acetamide
Show/Hide
|
C24H30F2N4O2
|
1
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| 1 |
Ki = 1.5 nM
|
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CP0476046
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(R)-1-[4-(2-Amino-ethyl)-4-methyl-piperidin-1-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
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C21H30F2N2O2
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1
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| 1 |
Ki = 1.5 nM
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CP0058613
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CAS_132947
Show/Hide
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C64H77N13O6
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1
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| 1 |
Ki = 1.585 nM
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CP0399528
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1,9-di[4-(1-methyl-1,2,3,6-tetrahydro-5-pyridinyl)-1,2,5-thiadiazol-3-yloxy]nonane
Show/Hide
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C25H38N6O2S2
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1
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| 1 |
Ki = 1.66 nM
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CP0404348
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(R)-1-(4-Aminomethyl-piperidin-1-yl)-2-cyclopentyl-2-hydroxy-2-phenyl-ethanone
Show/Hide
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C19H28N2O2
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1
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| 1 |
Ki = 1.8 nM
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CP0778905
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(R)-3-(3-Hexylsulfanyl-pyrazin-2-yloxy)-1-aza-bicyclo[2.2.1]heptane hydrochloride
Show/Hide
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C16H26ClN3OS
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1
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| 1 |
Ki = 2 nM
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CP0440619
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1-azabicyclo[2.2.2]octan-3-yl N-[2-(4-fluorophenyl)ethyl]-N-phenylcarbamate
Show/Hide
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C22H25FN2O2
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1
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| 1 |
Ki = 2 nM
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CP0874916
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2-(5-(cyclohexyl(hydroxy)(phenyl)methyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
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C23H32INO2
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1
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| 1 |
Ki = 2.089 nM
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CP0379378
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2-Cyclopentyl-2-hydroxy-N-[1-(5-methyl-thiophen-3-ylmethyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
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C24H32N2O2S
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1
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| 1 |
Ki = 2.1 nM
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CP0373693
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(R)-1-(3-Aminomethyl-pyrrolidin-1-yl)-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
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C18H24F2N2O2
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1
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| 1 |
Ki = 2.1 nM
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CP0379405
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(R)-1-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-cyclopentyl-2-hydroxy-2-phenyl-ethanone
Show/Hide
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C20H30N2O2
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1
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| 1 |
Ki = 2.1 nM
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CP0869207
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(R)-2-((R)-2,2-diphenyl-[1,3]oxathiolan-5-yl)-1,1-dimethyl-pyrrolidinium iodide
Show/Hide
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C21H26INOS
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1
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| 1 |
Ki = 2.344 nM
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CP0062485
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4-(Diethylamino)-2-butynyl alpha-phenylcyclohexaneglycolic acid ester
Show/Hide
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C22H31NO3
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1
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| 1 |
Ki = 2.399 nM
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CP0461302
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(2R)-N-(1-benzylpiperidin-4-yl)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
Show/Hide
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C25H30F2N2O2
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1
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| 1 |
Ki = 2.4 nM
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CP0381014
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2-(3,3-Difluoro-cyclopentyl)-N-[1-(3-fluoro-benzyl)-piperidin-4-yl]-2-hydroxy-2-phenyl-acetamide
Show/Hide
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C25H29F3N2O2
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1
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| 1 |
Ki = 2.5 nM
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CP0393596
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(2R)-N-[1-[(4-amino-3-fluorophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
Show/Hide
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C25H30F3N3O2
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1
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| 1 |
Ki = 2.5 nM
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CP0379015
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N-(1-benzylpiperidin-4-yl)-2-cyclopentyl-2-hydroxy-2-phenylacetamide
Show/Hide
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C25H32N2O2
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1
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| 1 |
Ki = 2.6 nM
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CP0373659
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(R)-1-(4-Amino-piperidin-1-yl)-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
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C18H24F2N2O2
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1
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| 1 |
Ki = 3 nM
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CP0379399
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(2R)-N-[1-[(3-aminophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
Show/Hide
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C25H31F2N3O2
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1
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| 1 |
Ki = 3.2 nM
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CP0876058
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(2S,5'S)-1-methyl 2-(2,2-diphenyl-1,3-oxathiolan-5-yl)pirrolidine
Show/Hide
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C20H23NOS
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1
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| 1 |
Ki = 3.467 nM
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CP0378043
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2-Cyclopentyl-2-hydroxy-N-[1-(4-methyl-benzyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
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C26H34N2O2
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1
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| 1 |
Ki = 3.5 nM
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CP0515291
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(2R)-N-[1-[(4-aminophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
Show/Hide
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C25H31F2N3O2
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1
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| 1 |
Ki = 3.5 nM
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CP0431655
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2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(3-methoxy-benzyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
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C26H32F2N2O3
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1
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| 1 |
Ki = 4.4 nM
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CP0858902
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(+/-)-(6,6-Diphenyl-1,4-dioxan-2-yl)-N,N-dimethylmethanamine Oxalate
Show/Hide
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C21H25NO6
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1
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| 1 |
Ki = 4.571 nM
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CP0020189
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6-acetoxy-8-azonia-bicyclo[3.2.1]octane
Show/Hide
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C9H15NO2
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3
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| 1 |
Ki = 4.6 nM
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| 2 |
Ki = 21000 nM
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| 3 |
Ki = 21379.62 nM
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CP0404392
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(R)-1-(4-Amino-4-methyl-piperidin-1-yl)-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
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C19H26F2N2O2
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1
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| 1 |
Ki = 4.7 nM
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CP0384377
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2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-N-(1-thiophen-3-ylmethyl-piperidin-4-yl)-acetamide
Show/Hide
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C23H28F2N2O2S
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1
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| 1 |
Ki = 5.3 nM
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CP0010653
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2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-ethyl]-pyrrolidin-3-yl}-2,2-diphenyl-acetamide (Darifenacin)
Show/Hide
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C28H30N2O2
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1
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| 1 |
Ki = 5.5 nM
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CP0448156
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(R)-1-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
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C20H28F2N2O2
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1
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| 1 |
Ki = 6.6 nM
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CP0858486
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2-(5-(cyclohexyl(phenyl)methyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
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C23H32INO
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1
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| 1 |
Ki = 6.607 nM
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CP0378653
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1-[3-[4-[5-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]pentyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C30H43N5O2S
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1
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| 1 |
Ki = 6.761 nM
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CP0380577
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2-Cyclopentyl-2-hydroxy-N-[1-(3-methoxy-benzyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
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C26H34N2O3
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1
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| 1 |
Ki = 8.5 nM
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CP0465017
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2-Cyclopentyl-2-hydroxy-2-phenyl-N-(1-thiophen-3-ylmethyl-piperidin-4-yl)-acetamide
Show/Hide
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C23H30N2O2S
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1
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| 1 |
Ki = 9 nM
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CP0880938
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(S)-2-(5-((R)-cyclohexyl(hydroxy)(phenyl)methyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
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C23H32INO2
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1
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| 1 |
Ki = 9.12 nM
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CP0413084
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1-azabicyclo[2.2.2]octan-3-yl N-[2-(4-methoxyphenyl)ethyl]-N-phenylcarbamate
Show/Hide
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C23H28N2O3
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1
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| 1 |
Ki = 10 nM
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CP0415932
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1-[3-[4-[11-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]undecyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C36H55N5O2S
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1
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| 1 |
Ki = 10.96 nM
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CP0426808
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(R)-1-[4-(2-Amino-ethyl)-piperazin-1-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
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C19H27F2N3O2
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1
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| 1 |
Ki = 11 nM
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CP0480584
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(R)-1-(4-Aminomethyl-piperidin-1-yl)-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
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C19H26F2N2O2
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1
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| 1 |
Ki = 11 nM
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CP0858619
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2-(5-benzhydrylfuran-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
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C23H26INO
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1
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| 1 |
Ki = 11.48 nM
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CP0388205
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2-[5-[cyclohexyl(phenyl)methyl]furan-2-yl]-1-methylpyrrolidine
Show/Hide
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C22H29NO
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1
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| 1 |
Ki = 13.49 nM
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CP0437352
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(2R)-N-[1-[(5-aminopyridin-2-yl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
Show/Hide
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C24H30F2N4O2
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1
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| 1 |
Ki = 14 nM
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CP0849054
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1-[1-(3,3,3-Triphenyl-propionyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carboxylic acid (1-cyclohexylmethyl-piperidin-3-ylmethyl)-amide
Show/Hide
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C44H56N4O3
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1
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| 1 |
Ki = 14 nM
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CP0414993
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(R)-1-[1,4]Diazepan-1-yl-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
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C18H24F2N2O2
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1
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| 1 |
Ki = 14 nM
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CP0380674
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2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-N-(1-pyridin-2-ylmethyl-piperidin-4-yl)-acetamide
Show/Hide
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C24H29F2N3O2
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1
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| 1 |
Ki = 15 nM
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CP0858903
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(R)-(6,6-Diphenyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
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C20H26INO2
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1
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| 1 |
Ki = 16.22 nM
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CP0448093
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2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(3-hydroxymethyl-benzyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
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C26H32F2N2O3
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1
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| 1 |
Ki = 17 nM
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CP0178512
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(R)-2-Cyclopentyl-2-hydroxy-N-[1-(4-methyl-pent-3-enyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
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C24H36N2O2
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1
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| 1 |
Ki = 19 nM
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CP0420691
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(R)-1-[4-(2-Amino-acetyl)-piperazin-1-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
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C19H25F2N3O3
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1
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| 1 |
Ki = 21 nM
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CP0527516
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3-(6-Hexylsulfanyl-pyrazin-2-yloxy)-1-aza-bicyclo[2.2.1]heptane
Show/Hide
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C16H25N3OS
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1
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| 1 |
Ki = 22 nM
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CP0380673
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2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(4-methyl-pent-3-enyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
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C24H34F2N2O2
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1
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| 1 |
Ki = 22 nM
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CP0398877
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(R)-cyclohexyl-[5-[(2S)-1-methylpyrrolidin-2-yl]furan-2-yl]-phenylmethanol
Show/Hide
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C22H29NO2
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1
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| 1 |
Ki = 22.91 nM
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CP0495916
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(R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-N-piperidin-4-ylmethyl-acetamide
Show/Hide
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C19H26F2N2O2
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1
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| 1 |
Ki = 23 nM
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CP0917620
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2-(5-(hydroxydiphenylmethyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
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C23H26INO2
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1
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| 1 |
Ki = 23.44 nM
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CP0406016
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2-Cyclopentyl-2-hydroxy-2-phenyl-N-(1-pyridin-2-ylmethyl-piperidin-4-yl)-acetamide
Show/Hide
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C24H31N3O2
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1
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| 1 |
Ki = 26 nM
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CP0493913
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2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(6-methyl-pyridin-2-ylmethyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
|
C25H31F2N3O2
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1
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| 1 |
Ki = 26 nM
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CP0409449
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4-Nitro-benzoic acid 8-aza-bicyclo[3.2.1]oct-6-yl ester
Show/Hide
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C14H16N2O4
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2
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| 1 |
Ki = 29 nM
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| 2 |
Ki = 780 nM
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CP0413481
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1-[3-[4-[9-[1-[3-(2-oxo-3,4-dihydroquinolin-1-yl)propyl]piperidin-4-yl]nonyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C43H64N4O2
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1
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| 1 |
Ki = 29.51 nM
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CP0072535
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3-(3-Hexyloxy-pyrazin-2-yloxy)-1-aza-bicyclo[2.2.1]heptane
Show/Hide
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C16H25N3O2
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1
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| 1 |
Ki = 30 nM
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CP0406509
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3-(3-Hexylsulfanyl-pyrazin-2-ylsulfanyl)-1-aza-bicyclo[2.2.1]heptane
Show/Hide
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C16H25N3S2
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1
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| 1 |
Ki = 30 nM
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CP0447972
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(R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-1-piperazin-1-yl-ethanone
Show/Hide
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C17H22F2N2O2
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1
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| 1 |
Ki = 30 nM
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CP0413081
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1,3-benzodioxol-5-ylmethyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
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C22H24N2O4
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1
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| 1 |
Ki = 30 nM
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CP0217520
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AF-DX 384
Show/Hide
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C27H38N6O2
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1
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| 1 |
Ki = 30.9 nM
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CP0431004
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[5-(1-methylpyrrolidin-2-yl)furan-2-yl]-diphenylmethanol
Show/Hide
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C22H23NO2
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1
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| 1 |
Ki = 35.48 nM
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CP0875623
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(R)-(6,6-Diphenyl-1,4-dioxan-2-yl)-N,N-dimethylmethanamine Oxalate
Show/Hide
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C21H25NO6
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1
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| 1 |
Ki = 35.48 nM
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CP0503519
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2-Cyclopentyl-2-hydroxy-N-[1-(6-methyl-pyridin-2-ylmethyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
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C25H33N3O2
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1
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| 1 |
Ki = 36 nM
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CP0886180
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N-(2-{2-[(1-Cyclohexylmethyl-piperidin-3-ylmethyl)-carbamoyl]-ethylcarbamoyl}-ethyl)-3,3,3-triphenyl-propionamide
Show/Hide
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C40H52N4O3
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1
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| 1 |
Ki = 36 nM
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CP0415133
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(R)-1-[4-(2-Amino-2-methyl-propyl)-piperidin-1-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
|
C22H32F2N2O2
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1
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| 1 |
Ki = 37 nM
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CP0413078
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(3-fluoro-4-methylphenyl)methyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
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C22H25FN2O2
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1
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| 1 |
Ki = 40 nM
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CP0439204
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2-(5-benzhydrylfuran-2-yl)-1-methylpyrrolidine
Show/Hide
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C22H23NO
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1
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| 1 |
Ki = 42.66 nM
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CP0406146
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1-[3-[4-[13-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]tridecyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C38H59N5O2S
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1
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| 1 |
Ki = 44.67 nM
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CP0859818
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(R)-2-(5-((S)-cyclohexyl(hydroxy)(phenyl)methyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
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C23H32INO2
|
1
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| 1 |
Ki = 47.86 nM
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CP0225899
|
AQ-RA 741
Show/Hide
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C27H37N5O2
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1
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| 1 |
Ki = 50.12 nM
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CP0429871
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(R)-N-(4-Aminomethyl-cyclohexyl)-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-acetamide
Show/Hide
|
C20H28F2N2O2
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1
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| 1 |
Ki = 55 nM
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CP0054630
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((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-ylmethyl)-trimethyl-ammonium
Show/Hide
|
C9H20NO2+
|
2
|
| 1 |
Ki = 56 nM
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|
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| 2 |
Ki = 18197.01 nM
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CP0505389
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2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(4-methyl-pent-3-enyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
|
C24H34F2N2O2
|
1
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| 1 |
Ki = 57 nM
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CP0413082
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(3,4-dichlorophenyl)methyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C21H22Cl2N2O2
|
1
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| 1 |
Ki = 60 nM
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CP0464724
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2-(3-Fluoro-cyclopentyl)-2-hydroxy-N-[1-(4-methyl-pent-3-enyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
|
C24H35FN2O2
|
1
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| 1 |
Ki = 61 nM
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CP0394158
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(2R)-N-(1-cyclopropylmethyl-4-piperidinylmethyl)-1-((2S,4R)-4-hydroxy-1 -[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonylpyrrolidine-2-carboxamide
Show/Hide
|
C41H47F3N4O4
|
1
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| 1 |
Ki = 65 nM
|
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CP0408530
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N-[1-(cyclooctylmethyl)piperidin-4-yl]-2-cyclopentyl-2-hydroxy-2-phenylacetamide
Show/Hide
|
C27H42N2O2
|
1
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| 1 |
Ki = 70 nM
|
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CP0413080
|
(1-methylpiperidin-4-yl) N-[2-(4-fluorophenyl)ethyl]-N-phenylcarbamate
Show/Hide
|
C21H25FN2O2
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0413083
|
(3-fluoro-4-methoxyphenyl)methyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C22H25FN2O3
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0467303
|
(2R)-N-(1-cyclopentylmethyl-4-piperidinylmethyl)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonylpyrrolidine-2-carboxamide
Show/Hide
|
C43H51F3N4O4
|
1
|
| 1 |
Ki = 71 nM
|
|
|
|
CP0373261
|
2-(3,3-Difluoro-cyclopentyl)-N-(1-furan-3-ylmethyl-piperidin-4-yl)-2-hydroxy-2-phenyl-acetamide
Show/Hide
|
C23H28F2N2O3
|
1
|
| 1 |
Ki = 72 nM
|
|
|
|
CP0460754
|
(S)-3-(3-Hexylsulfanyl-pyrazin-2-yloxy)-1-aza-bicyclo[2.2.1]heptane
Show/Hide
|
C16H25N3OS
|
1
|
| 1 |
Ki = 75 nM
|
|
|
|
CP0380626
|
2-(3-Fluoro-cyclopentyl)-2-hydroxy-N-[1-(4-methyl-pent-3-enyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
|
C24H35FN2O2
|
1
|
| 1 |
Ki = 75 nM
|
|
|
|
CP0377612
|
N-[3-[[1-(cyclohexylmethyl)piperidin-3-yl]methylamino]-3-oxopropyl]-4-(3,3,3-triphenylpropanoylamino)butanamide
Show/Hide
|
C41H54N4O3
|
1
|
| 1 |
Ki = 77 nM
|
|
|
|
CP0399526
|
1-[3-[4-[3-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]propyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C28H39N5O2S
|
1
|
| 1 |
Ki = 77.62 nM
|
|
|
|
CP0402546
|
2-Hydroxy-2-(3-hydroxy-cyclopentyl)-N-[1-(4-methyl-pent-3-enyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
|
C24H36N2O3
|
1
|
| 1 |
Ki = 88 nM
|
|
|
|
CP0405296
|
3-[4-(2-Methyl-1H-imidazol-1-yl)-2-butynyl]oxyisoxazole sesquifumarate
Show/Hide
|
C11H11N3O2
|
1
|
| 1 |
Ki = 91.2 nM
|
|
|
|
CP0492334
|
(R)-1-[4-(3-Amino-propyl)-piperidin-1-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
|
C21H30F2N2O2
|
1
|
| 1 |
Ki = 92 nM
|
|
|
|
CP0376043
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chlorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-(4-piperidinylmethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C37H41Cl3N4O4
|
1
|
| 1 |
Ki = 93 nM
|
|
|
|
CP0413087
|
1-azabicyclo[2.2.2]octan-3-yl N-[2-(3,4-dimethoxyphenyl)ethyl]-N-phenylcarbamate
Show/Hide
|
C24H30N2O4
|
1
|
| 1 |
Ki = 95 nM
|
|
|
|
CP0859758
|
6-(3,3,3-Triphenyl-propionylamino)-hexanoic acid (1-cyclohexylmethyl-piperidin-3-ylmethyl)-amide
Show/Hide
|
C40H53N3O2
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0374791
|
Benzoic acid 8-aza-bicyclo[3.2.1]oct-6-yl ester
Show/Hide
|
C14H17NO2
|
2
|
| 1 |
Ki = 120 nM
|
|
|
| 2 |
Ki = 2800 nM
|
|
|
|
CP0847176
|
N-({2-[(1-Cyclohexylmethyl-piperidin-3-ylmethyl)-carbamoyl]-ethylcarbamoyl}-methyl)-3,3,3-triphenyl-propionamide
Show/Hide
|
C39H50N4O3
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0440614
|
(1-methylpiperidin-3-yl) N-[2-(4-fluorophenyl)ethyl]-N-phenylcarbamate
Show/Hide
|
C21H25FN2O2
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0510568
|
1-[4-(2-methylimidazol-1-yl)but-2-ynyl]pyrrolidin-2-one
Show/Hide
|
C12H15N3O
|
1
|
| 1 |
Ki = 120.23 nM
|
|
|
|
CP0378643
|
1-[3-[4-(11-hydroxyundecyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C28H46N2O2
|
1
|
| 1 |
Ki = 123.03 nM
|
|
|
|
CP0378051
|
(R)-3-(3-Hexylsulfanyl-pyrazin-2-yloxy)-1-aza-bicyclo[2.2.1]heptane; hydrochloride
Show/Hide
|
C16H25N3OS
|
1
|
| 1 |
Ki = 124 nM
|
|
|
|
CP0033479
|
(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine
Show/Hide
|
C17H19ClN2S
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0380678
|
(2R)-N-[1-(cyclohexylmethyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
Show/Hide
|
C25H36F2N2O2
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0418889
|
2-Cyclopentyl-N-(1-furan-3-ylmethyl-piperidin-4-yl)-2-hydroxy-2-phenyl-acetamide
Show/Hide
|
C23H30N2O3
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0376699
|
(R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-N-(2-piperidin-4-yl-ethyl)-acetamide
Show/Hide
|
C20H28F2N2O2
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0376760
|
(R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-1-[4-(2-methylamino-ethyl)-piperidin-1-yl]-2-phenyl-ethanone
Show/Hide
|
C21H30F2N2O2
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0437578
|
(R)-1-[4-(4-Amino-butyl)-piperidin-1-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
|
C22H32F2N2O2
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0849742
|
1-(3,3,3-Triphenyl-propionyl)-pyrrolidine-2-carboxylic acid {2-[(1-cyclohexylmethyl-piperidin-3-ylmethyl)-carbamoyl]-ethyl}-amide
Show/Hide
|
C42H54N4O3
|
1
|
| 1 |
Ki = 150 nM
|
|
|
|
CP0860436
|
1-(3,3,3-Triphenyl-propionyl)-pyrrolidine-2-carboxylic acid {[(1-cyclohexylmethyl-piperidin-3-ylmethyl)-carbamoyl]-methyl}-amide
Show/Hide
|
C41H52N4O3
|
1
|
| 1 |
Ki = 150 nM
|
|
|
|
CP0393457
|
(2R)-N-[1-(cycloheptylmethyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
Show/Hide
|
C26H38F2N2O2
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0067391
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-(4-piperidinylmethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C37H41F3N4O4
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0413077
|
3-(3,4-dichlorophenyl)propyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C23H26Cl2N2O2
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0413482
|
1-[3-[4-(13-hydroxytridecyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C30H50N2O2
|
1
|
| 1 |
Ki = 186.21 nM
|
|
|
|
CP0377860
|
8-azabicyclo[3.2.1]octan-6-yl propanoate
Show/Hide
|
C10H17NO2
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0440616
|
benzyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C21H24N2O2
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0388200
|
(S)-cyclohexyl-[5-[(2R)-1-methylpyrrolidin-2-yl]furan-2-yl]-phenylmethanol
Show/Hide
|
C22H29NO2
|
1
|
| 1 |
Ki = 190.55 nM
|
|
|
|
CP0392367
|
prop-2-enyl 17-methoxy-7-[(4-methoxyphenyl)methyl]-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C32H32N2O5
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0405956
|
N-[1-(cycloheptylmethyl)piperidin-4-yl]-2-cyclopentyl-2-hydroxy-2-phenylacetamide
Show/Hide
|
C26H40N2O2
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0506997
|
N-[1-(cyclohexylmethyl)piperidin-4-yl]-2-cyclopentyl-2-hydroxy-2-phenylacetamide
Show/Hide
|
C25H38N2O2
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0416520
|
3-(3-fluoro-4-methylphenyl)propyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C24H29FN2O2
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0391332
|
(R)-N-(3-Aminomethyl-phenyl)-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-acetamide
Show/Hide
|
C20H22F2N2O2
|
1
|
| 1 |
Ki = 210 nM
|
|
|
|
CP0393859
|
(2R)-N-(1-cyclopentyl-4-piperidinylmethyl)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)-propanoyl]pyrrolidine-2-yl)carbonylpyrrolidine-2-carboxamide
Show/Hide
|
C42H49F3N4O4
|
1
|
| 1 |
Ki = 210 nM
|
|
|
|
CP0390495
|
(2R)-N-(1-cyclobutylmethyl-4-piperidinylmethyl)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonylpyrrolidine-2-carboxamide
Show/Hide
|
C42H49F3N4O4
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0377264
|
(8-methyl-8-azabicyclo[3.2.1]octan-6-yl) propanoate
Show/Hide
|
C11H19NO2
|
1
|
| 1 |
Ki = 230 nM
|
|
|
|
CP0390496
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chlorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-(4-piperidinylethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C38H43Cl3N4O4
|
1
|
| 1 |
Ki = 260 nM
|
|
|
|
CP0514143
|
CAS_91533
Show/Hide
|
C20H24N2
|
1
|
| 1 |
Ki = 263.03 nM
|
|
|
|
CP0393635
|
1-[3-[4-(2-phenylethyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C25H32N2O
|
1
|
| 1 |
Ki = 263.03 nM
|
|
|
|
CP0404340
|
Benzoic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-6-yl ester
Show/Hide
|
C15H19NO2
|
2
|
| 1 |
Ki = 270 nM
|
|
|
| 2 |
Ki = 7700 nM
|
|
|
|
CP0408072
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine -2-yl)-carbonyl-N-(1-methyl-4-piperidinylmethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C38H43F3N4O4
|
1
|
| 1 |
Ki = 270 nM
|
|
|
|
CP0469418
|
(1-methylpiperidin-4-yl) N-[2-(4-methoxyphenyl)ethyl]-N-phenylcarbamate
Show/Hide
|
C22H28N2O3
|
1
|
| 1 |
Ki = 280 nM
|
|
|
|
CP0378645
|
1-[3-[4-(9-hydroxynonyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C26H42N2O2
|
1
|
| 1 |
Ki = 281.84 nM
|
|
|
|
CP0494196
|
3-(3-Hexyloxy-pyrazin-2-ylsulfanyl)-1-aza-bicyclo[2.2.1]heptane
Show/Hide
|
C16H25N3OS
|
1
|
| 1 |
Ki = 292 nM
|
|
|
|
CP0404810
|
N-[[1-(cyclohexylmethyl)piperidin-3-yl]methyl]-4-[[2-(3,3,3-triphenylpropanoylamino)acetyl]amino]butanamide
Show/Hide
|
C40H52N4O3
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0376654
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-[(3R)-3-piperidinylmethyl]-pyrrolidine-2-carboxamide
Show/Hide
|
C37H41F3N4O4
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0458127
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-(4-piperidinylethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C38H43F3N4O4
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0413079
|
3-(3,4-difluorophenyl)propyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C23H26F2N2O2
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0448605
|
(R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-N-piperidin-4-yl-acetamide
Show/Hide
|
C18H24F2N2O2
|
1
|
| 1 |
Ki = 310 nM
|
|
|
|
CP0232092
|
1-[3-(4-butylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C21H32N2O
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0543664
|
N-ethyl-2,2-dimethyl-N-[3-[1-[2-oxo-2-(6-oxo-5H-benzo[b][1,4]benzodiazepin-11-yl)ethyl]piperidin-4-yl]propyl]pentanamide
Show/Hide
|
C32H44N4O3
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0860901
|
(S)-2-(5-((S)-cyclohexyl(hydroxy)(phenyl)methyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
|
C23H32INO2
|
1
|
| 1 |
Ki = 331.13 nM
|
|
|
|
CP0381013
|
(2R)-N-[1-[[3-(aminomethyl)phenyl]methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
Show/Hide
|
C26H33F2N3O2
|
1
|
| 1 |
Ki = 340 nM
|
|
|
|
CP0440621
|
[(1R,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] N-[2-(4-methoxyphenyl)ethyl]-N-phenylcarbamate
Show/Hide
|
C24H30N2O3
|
1
|
| 1 |
Ki = 350 nM
|
|
|
|
CP0393625
|
1-[3-[4-(7-hydroxyheptyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C24H38N2O2
|
1
|
| 1 |
Ki = 354.81 nM
|
|
|
|
CP0378256
|
ethyl 7-benzyl-6-ethyl-17-methoxy-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C31H32N2O4
|
1
|
| 1 |
Ki = 363.08 nM
|
|
|
|
CP0116478
|
1-[3-(4-benzylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C24H30N2O
|
1
|
| 1 |
Ki = 363.08 nM
|
|
|
|
CP0416523
|
2-(3,4-dichlorophenyl)ethyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C22H24Cl2N2O2
|
1
|
| 1 |
Ki = 370 nM
|
|
|
|
CP0502455
|
(3S,3aS,4R,4aS,8aS,9aR)-4-[(E)-2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethenyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
|
C22H35NO2
|
1
|
| 1 |
Ki = 426.58 nM
|
|
|
|
CP0518455
|
3-(3-fluoro-4-methoxyphenyl)propyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C24H29FN2O3
|
1
|
| 1 |
Ki = 430 nM
|
|
|
|
CP0440485
|
(8-methyl-8-azabicyclo[3.2.1]octan-6-yl) cyclohexanecarboxylate
Show/Hide
|
C15H25NO2
|
2
|
| 1 |
Ki = 450 nM
|
|
|
| 2 |
Ki = 7000 nM
|
|
|
|
CP0431973
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chlorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-((3R)-3-piperidinylmethyl)-pyrrolidine-2-carboxamide
Show/Hide
|
C37H41Cl3N4O4
|
1
|
| 1 |
Ki = 460 nM
|
|
|
|
CP0378647
|
1-[3-[4-(5-hydroxypentyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C22H34N2O2
|
1
|
| 1 |
Ki = 467.74 nM
|
|
|
|
CP0480004
|
2-Cyclopentyl-2-hydroxy-2-phenyl-N-(1-pyridin-3-ylmethyl-piperidin-4-yl)-acetamide
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
Ki = 470 nM
|
|
|
|
CP0411640
|
1-[3-(4-pentylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C22H34N2O
|
1
|
| 1 |
Ki = 489.78 nM
|
|
|
|
CP0390498
|
(2R)-N-(1-ethyl-4-piperidinylmethyl)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonylpyrrolidine-2-carboxamide
Show/Hide
|
C39H45F3N4O4
|
1
|
| 1 |
Ki = 580 nM
|
|
|
|
CP0416517
|
3-(4-methoxyphenyl)propyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C24H30N2O3
|
1
|
| 1 |
Ki = 590 nM
|
|
|
|
CP0480587
|
(R)-2-((R)-3,3-Difluoro-cyclopentyl)-N-(2,3-dihydro-1H-isoindol-5-yl)-2-hydroxy-2-phenyl-acetamide
Show/Hide
|
C21H22F2N2O2
|
1
|
| 1 |
Ki = 630 nM
|
|
|
|
CP0416527
|
2-(1,3-benzodioxol-5-yl)ethyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C23H26N2O4
|
1
|
| 1 |
Ki = 630 nM
|
|
|
|
CP0393595
|
2-Cyclopentyl-2-hydroxy-2-phenyl-N-(1-pyridin-4-ylmethyl-piperidin-4-yl)-acetamide
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C24H31N3O2
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1
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| 1 |
Ki = 660 nM
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CP0411349
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(1-methyl-4-phenylpiperidin-4-yl)methyl 3-(4-methoxyphenyl)propanoate
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C23H29NO3
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1
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| 1 |
Ki = 670 nM
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CP0470418
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(R)-3-(3-Hexyloxy-pyrazin-2-yloxy)-1-aza-bicyclo[2.2.1]heptane
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C16H25N3O2
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1
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| 1 |
Ki = 690 nM
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CP0440617
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(1-methylpiperidin-3-yl) N-[2-(4-methoxyphenyl)ethyl]-N-phenylcarbamate
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C22H28N2O3
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1
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| 1 |
Ki = 690 nM
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CP0416518
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(4-methoxyphenyl)methyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
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C22H26N2O3
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1
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| 1 |
Ki = 710 nM
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CP0409523
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(R)-N-(4-Aminomethyl-phenyl)-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-acetamide
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C20H22F2N2O2
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1
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| 1 |
Ki = 740 nM
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CP0399660
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(R)-2-((R)-3,3-Difluoro-cyclopentyl)-1-[4-(2-dimethylamino-ethyl)-piperidin-1-yl]-2-hydroxy-2-phenyl-ethanone
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C22H32F2N2O2
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1
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| 1 |
Ki = 760 nM
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CP0440618
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2-(4-methoxyphenyl)ethyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
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C23H28N2O3
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1
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| 1 |
Ki = 760 nM
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CP0416519
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(3,4-dimethoxyphenyl)methyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
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C23H28N2O4
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1
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| 1 |
Ki = 770 nM
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CP0459315
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(1-methylpiperidin-4-yl) N-[2-(3,4-dimethoxyphenyl)ethyl]-N-phenylcarbamate
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C23H30N2O4
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1
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| 1 |
Ki = 770 nM
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CP0416522
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3-phenylpropyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
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C23H28N2O2
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1
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| 1 |
Ki = 780 nM
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CP0416526
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2-phenylethyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
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C22H26N2O2
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1
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| 1 |
Ki = 790 nM
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CP0485213
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(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-[1-(2-propyl)-4-piperidinylmethyl]pyrrolidine-2-carboxamide
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C34H36F3N3O4
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1
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| 1 |
Ki = 800 nM
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CP0880166
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2-(4-Piperidin-1-ylbut-2-yn-1-yl)isoxazolidin-3-one oxalate
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C14H20N2O6
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1
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| 1 |
Ki = 819 nM
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CP0392351
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ethyl 6-butyl-17-methylsulfanyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
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C26H30N2O3S
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1
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| 1 |
Ki = 870.96 nM
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CP0459891
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ethyl 17-methylsulfanyl-6-propyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
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C25H28N2O3S
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1
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| 1 |
Ki = 870.96 nM
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CP0403333
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1-azabicyclo[2.2.2]octan-3-yl (3E)-3-(pyridin-3-ylmethylidene)indene-1-carboxylate
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C23H22N2O2
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1
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| 1 |
Ki = 891.25 nM
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CP0459833
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2-(4-(pyrrolidin-1-yl)but-2-ynyl)isoxazolidin-3-one
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C11H16N2O2
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1
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| 1 |
Ki = 905 nM
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CP0383280
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8-azabicyclo[3.2.1]octan-6-yl cyclohexanecarboxylate
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C14H23NO2
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2
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| 1 |
Ki = 970 nM
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| 2 |
Ki = 20000 nM
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CP0374663
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(8-methyl-8-azabicyclo[3.2.1]octan-6-yl) 2,2,2-trichloroethyl carbonate
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C11H16Cl3NO3
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2
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| 1 |
Ki = 1000 nM
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| 2 |
Ki = 27000 nM
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CP0392482
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benzyl 17-methoxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C28H26N2O4
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1
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| 1 |
Ki = 1174.9 nM
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CP0415357
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methyl 17-methoxy-6,7-dimethyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C23H24N2O4
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1
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| 1 |
Ki = 1174.9 nM
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CP0393458
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2-Cyclopentyl-2-hydroxy-N-[1-(2-methyl-benzyl)-piperidin-4-yl]-2-phenyl-acetamide
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C26H34N2O2
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1
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| 1 |
Ki = 1200 nM
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CP0381401
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2-(4-methoxyphenyl)ethyl 1-methyl-4-phenylpiperidine-4-carboxylate
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C22H27NO3
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1
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| 1 |
Ki = 1200 nM
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CP0139206
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Arecaidine Propargyl Ester
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C10H13NO2
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1
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| 1 |
Ki = 1230.27 nM
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CP0443229
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(S)-cyclohexyl-[5-[(2S)-1-methylpyrrolidin-2-yl]furan-2-yl]-phenylmethanol
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C22H29NO2
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1
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| 1 |
Ki = 1230.27 nM
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CP0467135
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1-azabicyclo[2.2.2]octan-3-yl (3E)-3-(pyridin-4-ylmethylidene)indene-1-carboxylate
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C23H22N2O2
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1
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| 1 |
Ki = 1258.93 nM
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CP0376946
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prop-2-enyl 17-methoxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C24H24N2O4
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1
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| 1 |
Ki = 1318.26 nM
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CP0382995
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butyl 17-methoxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C25H28N2O4
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1
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| 1 |
Ki = 1318.26 nM
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CP0393079
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ethyl 17-methoxy-7-methyl-6-propyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C26H30N2O4
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1
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| 1 |
Ki = 1318.26 nM
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CP0409101
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ethyl 7-ethyl-17-methoxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C25H28N2O4
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1
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| 1 |
Ki = 1318.26 nM
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CP0440620
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3-(3,4-dimethoxyphenyl)propyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
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C25H32N2O4
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1
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| 1 |
Ki = 1460 nM
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CP0378979
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1-azabicyclo[2.2.2]octan-3-yl (3E)-3-(pyridin-2-ylmethylidene)indene-1-carboxylate
Show/Hide
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C23H22N2O2
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1
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| 1 |
Ki = 1479.11 nM
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CP0472845
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1-[3-(4-benzylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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C23H29N3O
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1
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| 1 |
Ki = 1479.11 nM
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CP0381042
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(3S,3aR,4R,4aS,8aR,9aS)-4-[(Z)-2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethenyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H35NO2
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1
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| 1 |
Ki = 1513.56 nM
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CP0492196
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ethyl 6-ethyl-17-methoxy-7-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C25H28N2O4
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1
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| 1 |
Ki = 1513.56 nM
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CP0403577
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(3S,3aR,4S,4aR,8aR,9aS)-4-[(E)-2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethenyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H35NO2
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1
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| 1 |
Ki = 1737.8 nM
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CP0407747
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ethyl 6-methyl-17-methylsulfanyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C23H24N2O3S
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1
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| 1 |
Ki = 1778.28 nM
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CP0390494
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(2R)-1-[(2S,4R)-4-hydroxy-1-(3,3,3-triphenylpropanoyl)pyrrolidine-2-yl]carbonyl-N-(4-piperidinylmethyl)pyrrolidine-2-carboxamide
Show/Hide
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C37H44N4O4
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1
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| 1 |
Ki = 1800 nM
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CP0413085
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[(1R,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] N-[2-(3,4-dimethoxyphenyl)ethyl]-N-phenylcarbamate
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C25H32N2O4
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1
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| 1 |
Ki = 1870 nM
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CP0376666
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(R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-1-[4-(2-piperidin-1-yl-ethyl)-piperidin-1-yl]-ethanone
Show/Hide
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C25H36F2N2O2
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1
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| 1 |
Ki = 1900 nM
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CP0848084
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[4-(4-chloro-phenylcarbamoyloxy)-but-2-ynyl]-trimethyl-ammonium chloride
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C14H18Cl2N2O2
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1
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| 1 |
Ki = 1949.84 nM
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CP0423369
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(McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2-ynyl]-trimethyl-ammonium; chloride
Show/Hide
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C14H18ClN2O2+
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1
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| 1 |
Ki = 1949.84 nM
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CP0377061
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ethyl 17-methoxy-6,7-dimethyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C24H26N2O4
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1
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| 1 |
Ki = 1995.26 nM
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CP0390497
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(2R)-1-[(2S,4R)-4-hydroxy-1-(3,3,3-triphenylpropanoyl)pyrrolidine-2-yl]carbonyl-N-(4-piperidinylethyl)pyrrolidine-2-carboxamide
Show/Hide
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C38H46N4O4
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1
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| 1 |
Ki = 2000 nM
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CP0404800
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ethyl 17-methoxy-6-propyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C25H28N2O4
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1
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| 1 |
Ki = 2041.74 nM
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CP0480403
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ethyl 6-ethyl-17-methoxy-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C24H26N2O4
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1
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| 1 |
Ki = 2187.76 nM
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CP0393626
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1-[3-[4-(2-phenylethyl)piperazin-1-yl]propyl]-3,4-dihydroquinolin-2-one
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C24H31N3O
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1
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| 1 |
Ki = 2290.87 nM
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CP0024400
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6-acetoxy-8-methyl-8-azonia-bicyclo[3.2.1]octane
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C10H17NO2
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1
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| 1 |
Ki = 2300 nM
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CP0480607
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(3S,3aS,4R,4aS,8aS,9aR)-4-[(Z)-2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethenyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H35NO2
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1
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| 1 |
Ki = 2344.23 nM
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CP0111182
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benzyl 5-[4-(3-ethoxy-3-oxopropyl)piperazin-1-yl]-1,3-dihydroisoindole-2-carboxylate
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C25H31N3O4
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1
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| 1 |
Ki = 2473 nM
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CP0377555
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5-benzyl-17-methoxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene
Show/Hide
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C27H26N2O2
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1
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| 1 |
Ki = 2511.89 nM
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CP0379138
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1-[3-[4-(3-hydroxypropyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C20H30N2O2
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1
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| 1 |
Ki = 2511.89 nM
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CP0393633
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1-[3-(4-propylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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C20H30N2O
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1
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| 1 |
Ki = 2511.89 nM
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CP0379402
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(3S,3aR,4S,4aR,8aR,9aS)-4-[(Z)-2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethenyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H35NO2
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1
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| 1 |
Ki = 2570.4 nM
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CP0411642
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1-[3-(4-butylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C20H31N3O
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1
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| 1 |
Ki = 2691.53 nM
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CP0489929
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1-[3-(4-phenylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C23H28N2O
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1
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| 1 |
Ki = 2884.03 nM
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CP0447909
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2-(4-methoxyphenyl)ethyl N-[(1-methyl-4-phenylpiperidin-4-yl)methyl]carbamate
Show/Hide
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C23H30N2O3
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1
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| 1 |
Ki = 2910 nM
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CP0409139
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ethyl 6-hexyl-17-methoxy-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C28H34N2O4
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1
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| 1 |
Ki = 3090.3 nM
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CP0392743
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(3S,3aR,4R,4aS,8aR,9aS)-4-[2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethynyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H33NO2
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1
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| 1 |
Ki = 3235.94 nM
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CP0418924
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(3S,3aS,4R,4aS,8aS,9aR)-4-[2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethynyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H33NO2
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1
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| 1 |
Ki = 3235.94 nM
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CP0425298
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ethyl 7-methyl-17-methylsulfanyl-6-propyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C26H30N2O3S
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1
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| 1 |
Ki = 3311.31 nM
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CP0858930
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5-phenyl-3-[(4-pyrrolidin-1-ylbut-2-yn-1-yl)oxy]isoxazole methiodide
Show/Hide
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C18H21IN2O2
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1
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| 1 |
Ki = 3376 nM
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CP0401417
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3-(4-methoxyphenyl)-N-[(1-methyl-4-phenylpiperidin-4-yl)methyl]propanamide
Show/Hide
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C23H30N2O2
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1
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| 1 |
Ki = 3440 nM
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CP0374692
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(1-methyl-4-phenylpiperidin-4-yl)methyl 3-(3,4-dimethoxyphenyl)propanoate
Show/Hide
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C24H31NO4
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1
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| 1 |
Ki = 3630 nM
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CP0878023
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Cis-((2R*,6S*)-6-Benzhydryl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
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C21H28INO2
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1
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| 1 |
Ki = 3801.89 nM
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CP0232093
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1-[3-(4-phenylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C22H27N3O
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1
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| 1 |
Ki = 4265.8 nM
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CP0374957
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2-Cyclopentyl-N-(1-cyclopentylmethyl-piperidin-4-yl)-2-hydroxy-2-phenyl-acetamide
Show/Hide
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C24H36N2O2
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1
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| 1 |
Ki = 4300 nM
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CP0440615
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(1-methylpiperidin-3-yl) N-[2-(3,4-dimethoxyphenyl)ethyl]-N-phenylcarbamate
Show/Hide
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C23H30N2O4
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1
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| 1 |
Ki = 4300 nM
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CP0880168
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1-[4-(4,5-dihydroisoxazol-3-yloxy)but-2-yn-1-yl]piperidine oxalate
Show/Hide
|
C14H20N2O6
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1
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| 1 |
Ki = 4550 nM
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CP0415400
|
Cevimeline
Show/Hide
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C10H17NOS
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1
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| 1 |
Ki = 4897.79 nM
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CP0374693
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(1-methyl-4-phenylpiperidin-4-yl)methyl N-[2-(3,4-dimethoxyphenyl)ethyl]carbamate
Show/Hide
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C24H32N2O4
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1
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| 1 |
Ki = 5090 nM
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CP0404711
|
ethyl 17-chloro-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C22H21ClN2O3
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1
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| 1 |
Ki = 5128.61 nM
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CP0895036
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2-(2-Furyl)-1-methylpyrrolidineMethiodide
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C10H16INO
|
1
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| 1 |
Ki = 5248.07 nM
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CP0408533
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(3S,3aR,4S,4aR,8aR,9aS)-4-[2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethynyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H33NO2
|
1
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| 1 |
Ki = 5370.32 nM
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CP0530916
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1-[2-(4-methoxyphenyl)ethyl]-3-[(1-methyl-4-phenylpiperidin-4-yl)methyl]urea
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C23H31N3O2
|
1
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| 1 |
Ki = 5400 nM
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CP0394494
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Milameline
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C8H14N2O
|
1
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| 1 |
Ki = 5623.41 nM
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CP0870440
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(S)-1,1-Dimethyl-2-(5-methyl-furan-2-yl)-pyrrolidinium
Show/Hide
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C11H18INO
|
1
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| 1 |
Ki = 5623.41 nM
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CP0462684
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(2R)-1,1-dimethyl-2-[(2S,5S)-2-methyl-1,3-oxathiolan-5-yl]pyrrolidin-1-ium
Show/Hide
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C10H20NOS+
|
1
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| 1 |
Ki = 5888.44 nM
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CP0858931
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5-phenyl-3-[(4-pyrrolidin-1-ylbut-2-yn-1-yl)oxy]-isoxazole fumarate
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C21H22N2O6
|
1
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| 1 |
Ki = 6141 nM
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CP0244206
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7-[4-imidazo[1,2-a]pyridin-5-yl-3-(trifluoromethyl)phenoxy]thieno[2,3-c]pyridine
Show/Hide
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C21H12F3N3OS
|
1
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| 1 |
Ki = 6600 nM
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CP0916821
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Cis-N,N,N-Trimethyl((2R*,6S*)-6-phenyl-1,4-dioxan-2-yl)methanaminium Iodide
Show/Hide
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C14H22INO2
|
1
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| 1 |
Ki = 6760.83 nM
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CP0858932
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2-[4-(4,5-dihydroisoxazol-3-yloxy)but-2-yn-1-yl]-1,2,3,4-tetrahydroisoquinoline methiodide
Show/Hide
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C17H21IN2O2
|
1
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| 1 |
Ki = 6958 nM
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CP0413086
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2-(3,4-dimethoxyphenyl)ethyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
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C24H30N2O4
|
1
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| 1 |
Ki = 6980 nM
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CP0393421
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2-(dimethylamino)ethyl (3E)-3-(pyridin-2-ylmethylidene)indene-1-carboxylate
Show/Hide
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C20H20N2O2
|
1
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| 1 |
Ki = 7079.46 nM
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CP0880167
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1-[4-(4,5-dihydroisoxazol-3-yloxy)but-2-yn-1-yl]piperidine methiodide
Show/Hide
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C13H21IN2O2
|
1
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| 1 |
Ki = 7367 nM
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CP0895034
|
2-(5-Methyl-2-furyl)-1-methylpyrrolidine Methiodide
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C11H18INO
|
1
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| 1 |
Ki = 7413.1 nM
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CP0402148
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17-methoxy-6-methyl-5-(3-methyl-1,2,4-oxadiazol-5-yl)-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene
Show/Hide
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C23H22N4O3
|
1
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| 1 |
Ki = 7585.78 nM
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CP0873039
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5-methyl-3-[(4-pyrrolidin-1-ylbut-2-yn-1-yl)oxy]isoxazole methiodide
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C13H19IN2O2
|
1
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| 1 |
Ki = 7680 nM
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CP0249974
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5-methylfurmethide
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C9H16NO+
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1
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| 1 |
Ki = 7943.28 nM
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CP0373254
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(2S)-1,1-dimethyl-2-[(2S,5S)-2-methyl-1,3-oxathiolan-5-yl]pyrrolidin-1-ium
Show/Hide
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C10H20NOS+
|
1
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| 1 |
Ki = 8317.64 nM
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CP0394502
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trimethyl-[[(2R,6S)-6-methyl-1,4-dioxan-2-yl]methyl]azanium
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C9H20NO2+
|
1
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| 1 |
Ki = 8317.64 nM
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CP0064188
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4-[4-(6-methylimidazo[1,2-a]pyrazin-5-yl)-3-(trifluoromethyl)phenoxy]furo[3,2-c]pyridine
Show/Hide
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C21H13F3N4O2
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1
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| 1 |
Ki = 8500 nM
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CP0064183
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4-[3-methyl-4-(6-methylimidazo[1,2-a]pyrazin-5-yl)phenoxy]furo[3,2-c]pyridine
Show/Hide
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C21H16N4O2
|
1
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| 1 |
Ki = 8800 nM
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CP0369306
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4-[4-imidazo[1,2-a]pyridin-5-yl-3-(trifluoromethyl)phenoxy]furo[3,2-c]pyridine
Show/Hide
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C21H12F3N3O2
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1
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| 1 |
Ki = 9000 nM
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CP0409674
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N,N-dimethyl-2-[(3E)-3-(pyridin-2-ylmethylidene)inden-1-yl]ethanamine
Show/Hide
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C19H20N2
|
1
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| 1 |
Ki = 9549.93 nM
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CP0876609
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1-[4-(4,5-dihydroisoxazol-3-yloxy)but-2-yn-1-yl]indoline methiodide
Show/Hide
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C16H19IN2O2
|
1
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| 1 |
Ki > 10000 nM
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CP0897808
|
N,N-dimethyl-4-[(5-methylisoxazol-3-yl)oxy]-but-2-yn-1-amine fumarate
Show/Hide
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C14H18N2O6
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1
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| 1 |
Ki > 10000 nM
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CP0900137
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N,N-dimethyl-4-[(5-methylisoxazol-3-yl)oxy]but-2-yn-1-amine methiodide
Show/Hide
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C11H17IN2O2
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1
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| 1 |
Ki > 10000 nM
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CP0002070
|
1-(1H-Indol-3-yl)-2-propanamine
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C11H14N2
|
1
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| 1 |
Ki > 10000 nM
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CP0002071
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N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-N-prop-2-enylprop-2-en-1-amine
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C17H22N2O
|
1
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| 1 |
Ki > 10000 nM
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CP0635067
|
2-amino-6-chloro-3,4-dihydroquinazoline hydrochloride
Show/Hide
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C8H9Cl2N3
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1
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| 1 |
Ki > 10000 nM
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CP0381400
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N-[2-(4-methoxyphenyl)ethyl]-1-methyl-4-phenylpiperidine-4-carboxamide
Show/Hide
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C22H28N2O2
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1
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| 1 |
Ki > 10000 nM
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CP0401297
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3-(3,4-dimethoxyphenyl)-N-[(1-methyl-4-phenylpiperidin-4-yl)methyl]propanamide
Show/Hide
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C24H32N2O3
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1
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| 1 |
Ki > 10000 nM
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CP0431550
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1-[2-(3,4-dimethoxyphenyl)ethyl]-3-[(1-methyl-4-phenylpiperidin-4-yl)methyl]urea
Show/Hide
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C24H33N3O3
|
1
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| 1 |
Ki > 10000 nM
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CP0054519
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(1R,12R,13S,17R,21S)-12-ethyl-18-propyl-7-(trifluoromethyl)-10,18-diazapentacyclo[11.7.1.02,11.04,9.017,21]henicosa-2(11),3,5,7,9-pentaene
Show/Hide
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C25H31F3N2
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1
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| 1 |
Ki > 10000 nM
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CP0085414
|
(3aS,6R,6aS,9aR,9bR)-6-benzyl-1-methyl-3,3a,4,6,6a,7,8,9,9a,9b-decahydro-2H-benzo[de]quinolin-5-one
Show/Hide
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C20H27NO
|
1
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| 1 |
Ki > 10000 nM
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CP0387083
|
(3aS,9bS)-3a-methyl-5-phenyl-2,3,4,9b-tetrahydro-1H-pyrrolo[2,3-c]quinoline
Show/Hide
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C18H20N2
|
1
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| 1 |
Ki > 10000 nM
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CP0391120
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(1S,2R)-1-ethyl-7-methoxy-2-methyl-3,4-dihydro-1H-naphthalen-2-amine
Show/Hide
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C14H21NO
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1
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| 1 |
Ki > 10000 nM
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CP0391121
|
(3S,4S)-4-ethyl-3,6-dimethyl-2,4-dihydrochromen-3-amine
Show/Hide
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C13H19NO
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1
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| 1 |
Ki > 10000 nM
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CP0391154
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(3aS,9bS)-7,9-dimethoxy-3a-methyl-2,3,4,9b-tetrahydro-1H-chromeno[3,4-b]pyrrole
Show/Hide
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C14H19NO3
|
1
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| 1 |
Ki > 10000 nM
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CP0411059
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(3S,4S)-4-ethyl-3-methyl-1-phenyl-2,4-dihydroquinolin-3-amine
Show/Hide
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C18H22N2
|
1
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| 1 |
Ki > 10000 nM
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CP0127400
|
(-)-Pramipexole
Show/Hide
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C10H17N3S
|
1
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| 1 |
Ki > 10000 nM
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CP0374691
|
2-(3,4-dimethoxyphenyl)ethyl 1-methyl-4-phenylpiperidine-4-carboxylate
Show/Hide
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C23H29NO4
|
1
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| 1 |
Ki = 10800 nM
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CP0386217
|
(+)-CIS-DIOXOLANE
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C8H18NO2+
|
1
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| 1 |
Ki = 10964.78 nM
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CP0412497
|
trimethyl-[[(2R,5R)-2-methyl-1,3-oxathiolan-5-yl]methyl]azanium
Show/Hide
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C8H18NOS+
|
1
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| 1 |
Ki = 10964.78 nM
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CP0848059
|
SID855871
Show/Hide
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C8H18INO2
|
1
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| 1 |
Ki = 10964.78 nM
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CP0410895
|
2-(dimethylamino)ethyl (3E)-3-(pyridin-3-ylmethylidene)indene-1-carboxylate
Show/Hide
|
C20H20N2O2
|
1
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| 1 |
Ki = 11481.54 nM
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CP0379047
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2-(dimethylamino)ethyl (3E)-3-(pyridin-4-ylmethylidene)indene-1-carboxylate
Show/Hide
|
C20H20N2O2
|
1
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| 1 |
Ki = 12022.64 nM
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CP0393627
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1-[3-(4-methylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C18H26N2O
|
1
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| 1 |
Ki = 12022.64 nM
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CP0845388
|
Cis-N,N,N-trimethyl-1-((2R,6S)-6-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C9H20INO2
|
2
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| 1 |
Ki = 12882.5 nM
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| 2 |
Ki = 30199.52 nM
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CP0067390
|
ethyl 6-butyl-17-methoxy-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C26H30N2O4
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1
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| 1 |
Ki = 13182.57 nM
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CP0845041
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(R)-1,1-Dimethyl-2-(5-methyl-furan-2-yl)-pyrrolidinium
Show/Hide
|
C11H18INO
|
1
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| 1 |
Ki = 13803.84 nM
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CP0407925
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(2S)-1,1-dimethyl-2-[(2R,5R)-2-methyl-1,3-oxathiolan-5-yl]pyrrolidin-1-ium
Show/Hide
|
C10H20NOS+
|
1
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| 1 |
Ki = 14125.38 nM
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CP0509683
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(2R)-2-(5-methylfuran-2-yl)pyrrolidine
Show/Hide
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C9H13NO
|
1
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| 1 |
Ki = 14454.4 nM
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CP0877929
|
Cis-((2R*,6S*)-6-Ethyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
|
C10H22INO2
|
1
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| 1 |
Ki = 15488.17 nM
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CP0895136
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Trans-((2R*,6R*)-6-Benzhydryl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
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C21H28INO2
|
1
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| 1 |
Ki = 15848.93 nM
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CP0449315
|
N,N-dimethyl-2-[(3E)-3-(pyridin-3-ylmethylidene)inden-1-yl]ethanamine
Show/Hide
|
C19H20N2
|
1
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| 1 |
Ki = 18620.87 nM
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CP0485774
|
(2R)-1,1-dimethyl-2-[(2R,5R)-2-methyl-1,3-oxathiolan-5-yl]pyrrolidin-1-ium
Show/Hide
|
C10H20NOS+
|
1
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| 1 |
Ki = 19054.61 nM
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CP0859660
|
N,N,N-Trimethyl((2R*,5R*)-5,6,6-trimethyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C11H24INO2
|
1
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| 1 |
Ki = 19952.62 nM
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CP0474634
|
ethyl 17-methoxy-6-pentyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C27H32N2O4
|
1
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| 1 |
Ki = 20417.38 nM
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CP0848677
|
SID50106828
Show/Hide
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C11H19IN2O
|
1
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| 1 |
Ki = 20417.38 nM
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CP0394497
|
(2S)-1,1-dimethyl-2-[(2S,4R)-2-methyl-1,3-dioxolan-4-yl]pyrrolidin-1-ium
Show/Hide
|
C10H20NO2+
|
1
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| 1 |
Ki = 21379.62 nM
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CP0374978
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(3E)-N-[2-(dimethylamino)ethyl]-N-methyl-3-(pyridin-2-ylmethylidene)indene-1-carboxamide
Show/Hide
|
C21H23N3O
|
1
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| 1 |
Ki = 21877.62 nM
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CP0376953
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N-ethyl-17-methoxy-N,6-dimethyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxamide
Show/Hide
|
C24H27N3O3
|
1
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| 1 |
Ki = 21877.62 nM
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CP0431291
|
ethyl 17-hydroxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C22H22N2O4
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1
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| 1 |
Ki > 21877.62 nM
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CP0393373
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(3E)-N-[2-(dimethylamino)ethyl]-3-(pyridin-4-ylmethylidene)indene-1-carboxamide
Show/Hide
|
C20H21N3O
|
1
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| 1 |
Ki = 23988.33 nM
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CP0859714
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((2R*,5S*,6S*)-5,6-Dimethyl-1,4-dioxan-2-yl)-N,N,Ntrimethylmethanaminium iodide
Show/Hide
|
C10H22INO2
|
1
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| 1 |
Ki = 24547.09 nM
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CP0425884
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2-(3,4-dimethoxyphenyl)ethyl 1-methyl-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate
Show/Hide
|
C23H27NO4
|
1
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| 1 |
Ki = 25300 nM
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CP0528917
|
[(3S)-1-azabicyclo[2.2.1]heptan-3-yl] N-methylcarbamate
Show/Hide
|
C8H14N2O2
|
1
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| 1 |
Ki = 26000 nM
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CP0875624
|
Trans-N,N,N-Trimethyl((2R*,6R*)-6-phenyl-1,4-dioxan-2-yl)methanaminium Iodide
Show/Hide
|
C14H22INO2
|
1
|
| 1 |
Ki = 26302.68 nM
|
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CP0429992
|
(3E)-N-[2-(dimethylamino)ethyl]-3-(pyridin-2-ylmethylidene)indene-1-carboxamide
Show/Hide
|
C20H21N3O
|
1
|
| 1 |
Ki = 26915.35 nM
|
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CP0898948
|
2-(5-Methyl-2-furyl)-1-methylpyrrolidine
Show/Hide
|
C10H15NO
|
1
|
| 1 |
Ki = 26915.35 nM
|
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CP0430112
|
(3E)-N-[2-(dimethylamino)ethyl]-3-(pyridin-3-ylmethylidene)indene-1-carboxamide
Show/Hide
|
C20H21N3O
|
1
|
| 1 |
Ki = 28183.83 nM
|
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CP0377730
|
(4-methylpiperazin-1-yl)-[(3E)-3-(pyridin-4-ylmethylidene)inden-1-yl]methanone
Show/Hide
|
C21H21N3O
|
1
|
| 1 |
Ki = 29512.09 nM
|
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CP0447908
|
N-[2-(3,4-dimethoxyphenyl)ethyl]-1-methyl-4-phenylpiperidine-4-carboxamide
Show/Hide
|
C23H30N2O3
|
1
|
| 1 |
Ki > 30000 nM
|
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CP0895035
|
(S)-2-Furan-2-yl-1,1-dimethyl-pyrrolidinium
Show/Hide
|
C10H16INO
|
1
|
| 1 |
Ki = 30902.95 nM
|
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CP0910891
|
2-(2-Furyl)-1-methylpyrrolidine
Show/Hide
|
C9H13NO
|
1
|
| 1 |
Ki = 33113.11 nM
|
|
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CP0433872
|
(2S)-1-methyl-2-(5-methylfuran-2-yl)pyrrolidine
Show/Hide
|
C10H15NO
|
1
|
| 1 |
Ki = 36307.81 nM
|
|
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CP0902206
|
N,N,N-Trimethyl((2R*,5S*)-5,6,6-trimethyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C11H24INO2
|
1
|
| 1 |
Ki = 38018.94 nM
|
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CP0876494
|
2-(5-Methyl-2-furyl)-pyrrolidine
Show/Hide
|
C9H13NO
|
1
|
| 1 |
Ki = 38018.94 nM
|
|
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CP0500729
|
(2S)-2-(furan-2-yl)-1-methylpyrrolidine
Show/Hide
|
C9H13NO
|
1
|
| 1 |
Ki = 43651.58 nM
|
|
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CP0372904
|
(2R)-1-methyl-2-(5-methylfuran-2-yl)pyrrolidine
Show/Hide
|
C10H15NO
|
1
|
| 1 |
Ki = 44668.36 nM
|
|
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CP0372804
|
(2R)-2-(furan-2-yl)pyrrolidine
Show/Hide
|
C8H11NO
|
1
|
| 1 |
Ki = 46773.51 nM
|
|
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CP0859477
|
(6,6-Dimethyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium iodide
Show/Hide
|
C10H22INO2
|
1
|
| 1 |
Ki = 47863.01 nM
|
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CP0405252
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(3E)-N-[2-(dimethylamino)ethyl]-N-methyl-3-(pyridin-3-ylmethylidene)indene-1-carboxamide
Show/Hide
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C21H23N3O
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1
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| 1 |
Ki = 48977.88 nM
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CP0910892
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(R)-2-Furan-2-yl-1,1-dimethyl-pyrrolidinium
Show/Hide
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C10H16INO
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1
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| 1 |
Ki = 51286.14 nM
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CP0412496
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(2R)-1,1-dimethyl-2-[(2S,4R)-2-methyl-1,3-dioxolan-4-yl]pyrrolidin-1-ium
Show/Hide
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C10H20NO2+
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1
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| 1 |
Ki = 52480.75 nM
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CP0372805
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(2S)-2-(furan-2-yl)pyrrolidine
Show/Hide
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C8H11NO
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1
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| 1 |
Ki = 63095.73 nM
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CP0845387
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N,N,N-Trimethyl((2R*,6S*)-5,5,6-trimethyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
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C11H24INO2
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1
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| 1 |
Ki = 67608.3 nM
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CP0474436
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trimethyl-[[(2S,6S)-6-methyl-1,4-dioxan-2-yl]methyl]azanium;iodide
Show/Hide
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C9H20NO2+
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1
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| 1 |
Ki = 74131.02 nM
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CP0465871
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(2R)-2-(furan-2-yl)-1-methylpyrrolidine
Show/Hide
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C9H13NO
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1
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| 1 |
Ki = 77624.71 nM
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CP0455031
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(2R,3R,5R)-5-[(2S)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide;iodide
Show/Hide
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C10H20INO2S
|
1
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| 1 |
Ki = 93325.43 nM
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CP0373252
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(2R,5R)-5-[(2S)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide
Show/Hide
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C10H20NO2S+
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1
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| 1 |
Ki = 93325.43 nM
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CP0859717
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N,N,N-Trimethyl((2R*,6R*)-5,5,6-trimethyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
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C11H24INO2
|
1
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| 1 |
Ki = 95499.26 nM
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CP0859476
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((2S*,5S*,6S*)-5,6-Dimethyl-1,4-dioxan-2-yl)-N,N,Ntrimethylmethanaminium iodide
Show/Hide
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C10H22INO2
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1
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| 1 |
Ki > 100000 nM
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CP0859713
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(2R*,5S*)-N,N,N-Trimethyl-(5-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
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C9H20INO2
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1
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| 1 |
Ki > 100000 nM
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CP0859715
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((2R*,5R*,6S*)-5,6-Dimethyl-1,4-dioxan-2-yl)-N,N,Ntrimethylmethanaminium iodide
Show/Hide
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C10H22INO2
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1
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| 1 |
Ki > 100000 nM
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CP0859716
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()-(2R,6R)-N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
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C9H20INO2
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2
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| 1 |
Ki > 100000 nM
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| 2 |
Ki < 100000 nM
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CP0864337
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N,N,N-trimethyl-1-((2R,5R)-5-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
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C9H20INO2
|
1
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| 1 |
Ki > 100000 nM
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CP0868051
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(5,5-Dimethyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium iodide
Show/Hide
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C10H22INO2
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1
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| 1 |
Ki > 100000 nM
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CP0904026
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((2R*,5S*,6R*)-5,6-Dimethyl-1,4-dioxan-2-yl)-N,N,Ntrimethylmethanaminium iodide
Show/Hide
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C10H22INO2
|
1
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| 1 |
Ki > 100000 nM
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CP0916016
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N,N,N-Trimethyl(5,5,6,6-tetramethyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
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C12H26INO2
|
1
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| 1 |
Ki > 100000 nM
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CP0867621
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Trans-((2R*,6R*)-6-Ethyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
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C10H22INO2
|
1
|
| 1 |
Ki > 100000 nM
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CP0407014
|
(5S,2'S)-5-(1-methyl-2-pyrrolidinyl)oxazolidinone
Show/Hide
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C8H14N2O2
|
1
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| 1 |
Ki > 100000 nM
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CP0414425
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(5R,2'S)-5-(1-methyl-2-pyrrolidinyl)oxazolidinone
Show/Hide
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C8H14N2O2
|
1
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| 1 |
Ki > 100000 nM
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CP0846921
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(S)-N,N,N-trimethyl-1-(2-oxooxazolidin-5-yl)methanaminium
Show/Hide
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C7H15N2O2+
|
1
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| 1 |
Ki > 100000 nM
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CP0846922
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(S)-2-(carbamoyloxymethyl)-1,1-dimethylpyrrolidinium
Show/Hide
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C8H17N2O2+
|
1
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| 1 |
Ki > 100000 nM
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CP0846927
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(R)-5-((dimethylamino)methyl)oxazolidin-2-one
Show/Hide
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C6H12N2O2
|
1
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| 1 |
Ki > 100000 nM
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CP0848614
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(S)-5-((dimethylamino)methyl)-3-methyloxazolidin-2-one
Show/Hide
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C7H14N2O2
|
1
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| 1 |
Ki > 100000 nM
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CP0856191
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(S)-(1-methylpyrrolidin-2-yl)methyl carbamate
Show/Hide
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C7H14N2O2
|
1
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| 1 |
Ki > 100000 nM
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CP0860582
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(R)-N,N,N-trimethyl-1-(3-methyl-2-oxooxazolidin-5-yl)methanaminium
Show/Hide
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C8H17N2O2+
|
1
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| 1 |
Ki > 100000 nM
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CP0861363
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(S)-N,N,N-trimethyl-1-(3-methyl-2-oxooxazolidin-5-yl)methanaminium
Show/Hide
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C8H17N2O2+
|
1
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| 1 |
Ki > 100000 nM
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CP0866588
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(R)-N,N,N-trimethyl-1-(2-oxooxazolidin-5-yl)methanaminium
Show/Hide
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C7H15N2O2+
|
1
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| 1 |
Ki > 100000 nM
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CP0886638
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(R)-4-((S)-1-methylpyrrolidin-2-yl)oxazolidin-2-one
Show/Hide
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C8H14N2O2
|
1
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| 1 |
Ki > 100000 nM
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CP0902643
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(R)-5-((dimethylamino)methyl)-3-methyloxazolidin-2-one
Show/Hide
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C7H14N2O2
|
1
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| 1 |
Ki > 100000 nM
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CP0902877
|
(S)-5-((dimethylamino)methyl)oxazolidin-2-one
Show/Hide
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C6H12N2O2
|
1
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| 1 |
Ki > 100000 nM
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CP0912137
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(S)-4-((S)-1-methylpyrrolidin-2-yl)oxazolidin-2-one
Show/Hide
|
C8H14N2O2
|
1
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| 1 |
Ki > 100000 nM
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CP0848040
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(R)-N,N,N-Trimethyl-1-(2-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C9H20INO2
|
1
|
| 1 |
Ki > 100000 nM
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|
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CP0848060
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(R)-1-(1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium iodide
Show/Hide
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C8H18INO2
|
1
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| 1 |
Ki > 100000 nM
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|
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CP0866923
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N,N,N-trimethyl-1-((2R,3S)-3-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C9H20INO2
|
1
|
| 1 |
Ki > 100000 nM
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|
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CP0913147
|
N,N,N-trimethyl-1-((2R,3R)-3-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C9H20INO2
|
1
|
| 1 |
Ki > 100000 nM
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CP0307921
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C24H26FN3O3S2
|
1
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| 1 |
Ki > 1000 nM
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CP0379280
|
2-[3-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]propoxy]benzamide
Show/Hide
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C28H30N4O4S
|
1
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| 1 |
Ki > 1000 nM
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CP0467302
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(R)-N-((S)-piperidin-3-ylmethyl)-1-((S)-1-(3,3,3-triphenylpropanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamide
Show/Hide
|
C37H44N4O3
|
1
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| 1 |
Ki > 2500 nM
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CP0393862
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(2R)-1-[(2S,4R)-4-hydroxy-1-(3,3,3-triphenylpropanoyl)pyrrolidine-2-yl]carbonyl-N-((3R)-3-piperidinylmethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C37H44N4O4
|
1
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| 1 |
Ki > 2600 nM
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CP0377554
|
ethyl 15-chloro-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C22H21ClN2O3
|
1
|
| 1 |
Ki > 4365.16 nM
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CP0379516
|
(2S,3R,5S)-5-[(2S)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide;iodide
Show/Hide
|
C10H20INO2S
|
1
|
| 1 |
Ki < 100000 nM
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|
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CP0379517
|
(2R,3S,5R)-2-methyl-5-[(2R)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
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CP0379521
|
(2R,3S,5R)-5-[(2S)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide;iodide
Show/Hide
|
C10H20INO2S
|
1
|
| 1 |
Ki < 100000 nM
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CP0379525
|
(2S,3R,5S)-2-methyl-5-[(2S)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
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CP0379526
|
(2R,3R,5R)-5-[(2R)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide;iodide
Show/Hide
|
C10H20INO2S
|
1
|
| 1 |
Ki < 100000 nM
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|
|
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CP0379527
|
(2S,3S,5S)-2-methyl-5-[(2R)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
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|
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CP0419569
|
(2R,3S,5R)-5-[(2R)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide;iodide
Show/Hide
|
C10H20INO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
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CP0419583
|
(2S,3R,5S)-2-methyl-5-[(2R)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
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CP0424750
|
(2R,3R,5R)-2-methyl-5-[(2R)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
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CP0431823
|
(2R,3S,5R)-2-methyl-5-[(2S)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
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CP0432602
|
(2R,3R,5R)-2-methyl-5-[(2S)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
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CP0449147
|
(2S,3S,5S)-2-methyl-5-[(2S)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
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CP0461163
|
(2S,3S,5S)-5-[(2S)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide;iodide
Show/Hide
|
C10H20INO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
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CP0371717
|
trimethyl-[[(2S,6R)-6-methyl-1,4-dioxan-2-yl]methyl]azanium;iodide
Show/Hide
|
C9H20NO2+
|
1
|
| 1 |
Ki < 100000 nM
|
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