Brief Information of the Compound and Protein
Compound Name
3-(4-imidazol-1-ylbutoxy)-4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazole
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PubChem ID
CID: 44456863
Canonical SMILES
CN1CCC=C(C1)c1nsnc1OCCCCn1ccnc1
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Compound Formula C15H21N5OS
Compound Structure
Protein Name
Muscarinic acetylcholine receptor M1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Acetylcholine receptor
Uniprot ID
P11229
Gene Name
CHRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  4
1
IC50 = 870.96 nM
   TI
   LI
   LO
   TS
2
IC50 = 2290.87 nM
   TI
   LI
   LO
   TS
3
IC50 = 52480.75 nM
   TI
   LI
   LO
   TS
4
IC50 = 53703.18 nM
   TI
   LI
   LO
   TS