Brief Information of the Compound and Protein
Compound Name
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol
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PubChem ID
CID: 5002
SID: 14756073
Canonical SMILES
OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12
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Compound Formula C21H25N3O2S
Compound Structure
Protein Name
Muscarinic acetylcholine receptor M1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Acetylcholine receptor
Uniprot ID
P11229
Gene Name
CHRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
2
Ki = 398.11 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 56 nM
2 Ki = 100 nM
3 Ki = 1000 nM