Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[(1S,2S)-2-hydroxycyclohexyl]-6-[(6-methylpyridin-3-yl)methyl]benzo[h]quinazolin-4-one
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 PubChem ID
CID: 46207733
SID: 96061976
Canonical SMILES
Cc1ccc(Cc2cc3c(ncn([C@H]4CCCC[C@@H]4O)c3=O)c3ccccc23)cn1
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Compound Formula C25H25N3O2
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P11229
Gene Name
CHRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000943 CellSensor NFAT-bla CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 < 100 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 63 nM
   TI
   LI
   LO
   TS
2
EC50 > 2000 nM
   TI
   LI
   LO
   TS
3
Ki = 8 nM
   TI
   LI
   LO
   TS