Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
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 PubChem ID
CID: 1476756
SID: 29205427
Canonical SMILES
COc1ccc(Cn2cc(C(O)=O)c(=O)c3ccccc23)cc1
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Compound Formula C18H15NO4
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P11229
Gene Name
CHRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000943 CellSensor NFAT-bla CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 < 100 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
Activity = 660 nM
   TI
   LI
   LO
   TS
2
EC50 = 845 nM
   TI
   LI
   LO
   TS
3
EC50 = 8317.64 nM
   TI
   LI
   LO
   TS
4
Kd = 54954.09 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 820 nM