Brief Information of the Compound and Protein
Compound Name
5-[(2,6-difluoro-4-quinolin-6-ylphenyl)methyl]-4H-pyrrolo[3,4-d][1,3]thiazol-6-one
    Show/Hide
Canonical SMILES
Fc1cc(cc(F)c1CN1Cc2ncsc2C1=O)-c1ccc2ncccc2c1
    Show/Hide
Compound Formula C21H13F2N3OS
Compound Structure
Protein Name
Muscarinic acetylcholine receptor M1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P11229
Gene Name
CHRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 8000 nM
   TI
   LI
   LO
   TS