Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(3R,4S)-3-hydroxyoxan-4-yl]-5-methyl-4-[[4-(1,3-thiazol-4-yl)phenyl]methyl]pyridine-2-carboxamide
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 PubChem ID
CID: 118663155
Canonical SMILES
Cc1cnc(cc1Cc1ccc(cc1)-c1cscn1)C(=O)N[C@H]1CCOC[C@@H]1O
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Compound Formula C22H23N3O3S
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P11229
Gene Name
CHRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  8
1
EC50 = 60 nM
   TI
   LI
   LO
   TS
2
EC50 = 365 nM
   TI
   LI
   LO
   TS
3
EC50 = 447 nM
   TI
   LI
   LO
   TS
4
EC50 = 3900 nM
   TI
   LI
   LO
   TS
5
EC50 >= 3900 nM
   TI
   LI
   LO
   TS
6
EC50 > 4000 nM
   TI
   LI
   LO
   TS
7
EC50 >= 9200 nM
   TI
   LI
   LO
   TS
8
Ki = 19 nM
   TI
   LI
   LO
   TS