Brief Information of the Compound and Protein
Compound Name
3-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]pyrido[3,4-d]pyrimidin-4-one
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PubChem ID
CID: 86298473
Canonical SMILES
Cn1cc2c(cccc2n1)-c1cc(F)c(Cn2cnc3cnccc3c2=O)c(F)c1
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Compound Formula C22H15F2N5O
Compound Structure
Protein Name
Muscarinic acetylcholine receptor M1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Acetylcholine receptor
Uniprot ID
P11229
Gene Name
CHRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 5300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 980 nM
2 EC50 > 10000 nM