| Compound ID |
Compound Name |
Compound Formula |
|
CP0006743
|
4-methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide
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C16H19NO3S
|
1
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| 1 |
EC50 > 50118.72 nM
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|
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CP0048714
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(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-{2-[(3-chloro-propane-1-sulfonyl)-propyl-amino]-ethyl}-2-(3-fluoro-4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid
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C27H34ClFN2O7S
|
1
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| 1 |
IC50 = 0.14 nM
|
|
|
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CP0113237
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(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(3-fluoro-4-methoxy-phenyl)-1-{2-[propyl-(4,4,4-trifluoro-butane-1-sulfonyl)-amino]-ethyl}-pyrrolidine-3-carboxylic acid
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C28H34F4N2O7S
|
1
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| 1 |
IC50 = 0.2 nM
|
|
|
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CP0395698
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(3S)-3-[[(2S)-5-amino-2-[[(2S)-2-[[(1R,4S,7S,10S,13S,16S,19S,22S,25R,28S,31R,36R,39S,42S,45S)-31-amino-22,42-bis(2-amino-2-oxoethyl)-39-benzyl-4,7-bis(2-carboxyethyl)-10,19-bis(carboxymethyl)-13,28-bis[(1R)-1-hydroxyethyl]-45-(2-methylpropyl)-16-(2-methylsulfanylethyl)-3,6,9,12,15,18,21,24,27,30,38,41,44,47-tetradecaoxo-33,34,49,50-tetrathia-2,5,8,11,14,17,20,23,26,29,37,40,43,46-tetradecazabicyclo[23.22.4]henpentacontane-36-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-oxopentanoyl]amino]-4-[[(2S)-1-[[(2S,3S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
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C103H147N27O37S5
|
1
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| 1 |
IC50 = 0.208 nM
|
|
|
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CP0084273
|
(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(3-fluoro-4-methoxy-phenyl)-1-{2-[(pentane-1-sulfonyl)-propyl-amino]-ethyl}-pyrrolidine-3-carboxylic acid
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|
C29H39FN2O7S
|
1
|
| 1 |
IC50 = 0.28 nM
|
|
|
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CP0155304
|
(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-{2-[(butane-1-sulfonyl)-propyl-amino]-ethyl}-2-(3-fluoro-4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid
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C28H37FN2O7S
|
1
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| 1 |
IC50 = 0.47 nM
|
|
|
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CP0155329
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(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(3-fluoro-4-methoxy-phenyl)-1-{2-[(hexane-1-sulfonyl)-propyl-amino]-ethyl}-pyrrolidine-3-carboxylic acid
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C30H41FN2O7S
|
1
|
| 1 |
IC50 = 0.48 nM
|
|
|
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CP0372766
|
N-[3-[6-[(4-tert-butylphenyl)sulfonylamino]-2-cyclopropyl-5-(2-methoxyphenoxy)pyrimidin-4-yl]oxypropyl]thiophene-2-sulfonamide
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|
C31H36N4O7S3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
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CP0483059
|
5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[3-(thiophene-2-sulfonylamino)-propoxy]-pyrimidin-4-yl}-amide
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|
C29H33N5O7S3
|
1
|
| 1 |
IC50 = 4 nM
|
|
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CP0490188
|
5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-[2-(toluene-4-sulfonylamino)-ethoxy]-2-(3,4,5-trimethoxy-phenyl)-pyrimidin-4-yl]-amide
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|
C37H41N5O10S2
|
1
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| 1 |
IC50 = 4 nM
|
|
|
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CP0498524
|
N-[3-[6-[(4-tert-butylphenyl)sulfonylamino]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]oxypropyl]thiophene-2-sulfonamide
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|
C32H34N6O7S3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
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CP0406450
|
(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
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|
C30H26Cl2N4O4
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
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CP0376450
|
5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-2-(3,4,5-trimethoxy-phenyl)-pyrimidin-4-yl]-amide
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|
C34H37N5O10S3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
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CP0404038
|
(S)-[(S)-5-(3-Butyl-phenyl)-1-(2-chloro-6-fluoro-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
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|
C34H34ClFN4O4
|
1
|
| 1 |
IC50 = 7.1 nM
|
|
|
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CP0404589
|
5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-[2-(toluene-4-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
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|
C32H38N6O8S2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
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CP0405216
|
(S)-[(S)-1-(2-Chloro-6-fluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
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|
C30H26ClFN4O4
|
1
|
| 1 |
IC50 = 10.9 nM
|
|
|
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CP0401637
|
(S)-[(S)-1-(4-Butyl-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
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|
C34H36N4O4
|
1
|
| 1 |
IC50 = 11.1 nM
|
|
|
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CP0430251
|
N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(4-methylphenyl)pyrimidin-4-yl]-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide
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|
C27H28BrN5O5S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
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CP0511248
|
4-[5-(2-methoxyphenoxy)-2-morpholin-4-yl-6-[(5-propan-2-ylpyridin-2-yl)sulfonylamino]pyrimidin-4-yl]oxybut-2-ynyl N-pyrazin-2-ylcarbamate
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|
C32H34N8O8S
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
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CP0503016
|
(S)-[(S)-1-(3,5-Difluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
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|
C30H26F2N4O4
|
1
|
| 1 |
IC50 = 13.1 nM
|
|
|
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CP0504800
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2,3,6-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
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|
C30H25F3N4O4
|
1
|
| 1 |
IC50 = 13.2 nM
|
|
|
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CP0453427
|
(S)-[(S)-5-(3-Butyl-phenyl)-2-oxo-1-(2,4,6-trimethyl-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C37H42N4O4
|
1
|
| 1 |
IC50 = 13.6 nM
|
|
|
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CP0460798
|
5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[3-(propane-1-sulfonylamino)-propoxy]-pyrimidin-4-yl}-amide
Show/Hide
|
C28H37N5O7S2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
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CP0270554
|
3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid
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|
C28H27N3O6S
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
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CP0445448
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2,4,6-trimethyl-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
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|
C33H34N4O4
|
1
|
| 1 |
IC50 = 15.5 nM
|
|
|
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CP0471475
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(3-trifluoromethyl-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
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|
C31H27F3N4O4
|
1
|
| 1 |
IC50 = 15.6 nM
|
|
|
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CP0415579
|
N-[2-[6-[(4-tert-butylphenyl)sulfonylamino]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]oxyethyl]thiophene-2-sulfonamide
Show/Hide
|
C31H32N6O7S3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
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CP0481080
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(3-methyl-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C31H30N4O4
|
1
|
| 1 |
IC50 = 16.7 nM
|
|
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CP0498848
|
(S)-[(S)-1-(2,6-Difluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C30H26F2N4O4
|
1
|
| 1 |
IC50 = 17.7 nM
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|
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CP0375994
|
Butyl-carbamic acid 4-[6-(5-isopropyl-pyridine-2-sulfonylamino)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yloxy]-but-2-ynyl ester
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|
C33H36N6O7S
|
1
|
| 1 |
IC50 = 18 nM
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|
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CP0439605
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(3-phenyl-propyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
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|
C32H32N4O4
|
1
|
| 1 |
IC50 = 18.3 nM
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|
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CP0401415
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(S)-[(S)-1-(2,3-Difluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C30H26F2N4O4
|
1
|
| 1 |
IC50 = 18.5 nM
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|
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CP0460892
|
5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[3-(toluene-4-sulfonylamino)-propoxy]-pyrimidin-4-yl}-amide
Show/Hide
|
C32H37N5O7S2
|
1
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| 1 |
IC50 = 19 nM
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|
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CP0430886
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N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-4-tert-butylbenzenesulfonamide
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|
C31H30BrN7O6S
|
1
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| 1 |
IC50 = 19.3 nM
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CP0418841
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(S)-[(S)-1-(3-Chloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
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|
C30H27ClN4O4
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1
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| 1 |
IC50 = 21.4 nM
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CP0498902
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-2-oxo-1-phenethyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
Show/Hide
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C31H30N4O4
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1
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| 1 |
IC50 = 21.5 nM
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CP0453050
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methoxy-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C31H30N4O5
|
1
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| 1 |
IC50 = 22.4 nM
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CP0401636
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2-trifluoromethyl-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C31H27F3N4O4
|
1
|
| 1 |
IC50 = 22.5 nM
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CP0403654
|
5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-[3-(toluene-4-sulfonylamino)-propoxy]-pyrimidin-4-yl}-amide
Show/Hide
|
C33H40N6O8S2
|
1
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| 1 |
IC50 = 24 nM
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CP0467115
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5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-[2-(propane-1-sulfonylamino)-ethoxy]-2-(3,4,5-trimethoxy-phenyl)-pyrimidin-4-yl]-amide
Show/Hide
|
C33H41N5O10S2
|
1
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| 1 |
IC50 = 24 nM
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CP0497791
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(S)-[(S)-1-(4-tert-Butyl-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C34H36N4O4
|
1
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| 1 |
IC50 = 24.1 nM
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CP0509449
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(S)-[(S)-5-Biphenyl-3-yl-1-(2,6-dichloro-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C36H30Cl2N4O4
|
1
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| 1 |
IC50 = 25 nM
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CP0496089
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(3,4,5-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C30H25F3N4O4
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1
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| 1 |
IC50 = 25.3 nM
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CP0504149
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(S)-[(S)-1-(3-Bromo-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
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C30H27BrN4O4
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1
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| 1 |
IC50 = 25.5 nM
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CP0509170
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(3-fluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C30H27FN4O4
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1
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| 1 |
IC50 = 26.8 nM
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CP0505707
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4-[5-(2-methoxyphenoxy)-2-morpholin-4-yl-6-[(5-propan-2-ylpyridin-2-yl)sulfonylamino]pyrimidin-4-yl]oxybut-2-ynyl N-phenylcarbamate
Show/Hide
|
C34H36N6O8S
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1
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| 1 |
IC50 = 28 nM
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CP0464442
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-2-oxo-1-pentafluorophenylmethyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
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C30H23F5N4O4
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1
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| 1 |
IC50 = 28.8 nM
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CP0497793
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(3-trifluoromethoxy-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C31H27F3N4O5
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1
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| 1 |
IC50 = 30.8 nM
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CP0509219
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4-[5-(2-methoxyphenoxy)-6-[(5-propan-2-ylpyridin-2-yl)sulfonylamino]-2-pyridin-4-ylpyrimidin-4-yl]oxybut-2-ynyl N-phenylcarbamate
Show/Hide
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C35H32N6O7S
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1
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| 1 |
IC50 = 32 nM
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CP0511879
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(4-trifluoromethoxy-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C31H27F3N4O5
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1
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| 1 |
IC50 = 32.2 nM
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CP0418826
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(S)-[(S)-1-(3,4-Difluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C30H26F2N4O4
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1
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| 1 |
IC50 = 32.8 nM
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CP0452993
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(S)-[(S)-1-(2,5-Difluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C30H26F2N4O4
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1
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| 1 |
IC50 = 32.9 nM
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CP0460777
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4-tert-Butyl-N-[2-cyclopropyl-6-(3-ethanesulfonylamino-propoxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-benzenesulfonamide
Show/Hide
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C29H38N4O7S2
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1
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| 1 |
IC50 = 33 nM
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CP0409355
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(2-fluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C30H27FN4O4
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1
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| 1 |
IC50 = 33.1 nM
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CP0199771
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(S)-[(S)-5-(3-Butyl-phenyl)-2-oxo-1-(2,4,6-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C34H33F3N4O4
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1
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| 1 |
IC50 = 33.2 nM
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CP0441677
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-5-(4-fluoro-3-methyl-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C32H31FN4O5
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1
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| 1 |
IC50 = 33.2 nM
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CP0404037
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(S)-[(S)-5-(3-Butyl-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
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C35H38N4O5
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1
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| 1 |
IC50 = 36.5 nM
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CP0149851
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(S)-2-[(2S,3S)-2-((2S,3S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-3-phenyl-propionylamino)-4-methyl-pentanoylamino]-3-phenyl-propionylamino}-3-methyl-pentanoylamino)-3-methyl-pentanoylamino]-3-(1H-indol-3-yl)-propionic acid
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C49H65N7O8
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1
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| 1 |
IC50 = 37 nM
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CP0374283
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-1-hexyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
Show/Hide
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C29H34N4O4
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1
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| 1 |
IC50 = 39.9 nM
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CP0381696
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4-[5-(2-methoxyphenoxy)-2-morpholin-4-yl-6-[(5-propan-2-ylpyridin-2-yl)sulfonylamino]pyrimidin-4-yl]oxybut-2-ynyl N-pyridin-2-ylcarbamate
Show/Hide
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C33H35N7O8S
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1
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| 1 |
IC50 = 42 nM
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CP0477081
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N-[5-(2-methoxyphenoxy)-6-[2-(5-methylsulfanylpyrimidin-2-yl)oxyethoxy]-2-pyrimidin-2-ylpyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
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C30H29N7O6S2
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1
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| 1 |
IC50 = 42 nM
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CP0497165
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4-tert-Butyl-N-[6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yl]-benzenesulfonamide
Show/Hide
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C30H30N4O6S
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1
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| 1 |
IC50 = 44 nM
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CP0384016
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(4-trifluoromethyl-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
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C31H27F3N4O4
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1
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| 1 |
IC50 = 47.1 nM
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CP0453465
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(S)-((S)-1-Benzyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
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C30H28N4O4
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1
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| 1 |
IC50 = 47.4 nM
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CP0502159
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(2-methoxy-ethoxymethyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C27H30N4O6
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1
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| 1 |
IC50 = 47.8 nM
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CP0439363
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(S)-[(S)-1-(2-Chloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C30H27ClN4O4
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1
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| 1 |
IC50 = 48.1 nM
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CP0375923
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5-Isopropyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-morpholin-4-yl-pyrimidin-4-yl]-amide
Show/Hide
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C27H31N5O7S
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1
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| 1 |
IC50 = 49 nM
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CP0471481
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-5-(3-fluoro-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C31H29FN4O5
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1
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| 1 |
IC50 = 49.3 nM
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CP0425848
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-fluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C30H27FN4O4
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1
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| 1 |
IC50 = 49.7 nM
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CP0425849
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2,3,4-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C30H25F3N4O4
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1
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| 1 |
IC50 = 49.7 nM
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CP0502030
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4-tert-Butyl-N-[6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-morpholin-4-yl-pyrimidin-4-yl]-benzenesulfonamide
Show/Hide
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C29H34N4O7S
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1
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| 1 |
IC50 = 50 nM
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CP0404036
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methoxy-benzyl)-2-oxo-5-m-tolyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C32H32N4O5
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1
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| 1 |
IC50 = 50.7 nM
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CP0372656
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(2-methyl-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C31H30N4O4
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1
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| 1 |
IC50 = 55 nM
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CP0087311
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2-(1,3-benzodioxol-5-yl)-2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]-2-propylphenoxy]-N-(4-propan-2-ylphenyl)sulfonylacetamide
Show/Hide
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C38H42N4O6S
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1
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| 1 |
IC50 = 60 nM
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CP0499255
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2H-tetrazol-5-ylmethyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C25H24N8O4
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1
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| 1 |
IC50 = 65.6 nM
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CP0512447
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-5-(3-ethyl-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C33H34N4O5
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1
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| 1 |
IC50 = 68 nM
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CP0500970
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methyl-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C31H30N4O4
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1
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| 1 |
IC50 = 68.8 nM
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CP0134357
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3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethyl]-1-ethyl-1H-indole-6-carboxylic acid
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C29H28N2O7S
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1
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| 1 |
IC50 = 69 nM
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CP0384738
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4-{(S)-5-[(S)-Carboxy-(4,6-dimethyl-pyrimidin-2-yloxy)-methyl]-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[e][1,4]diazepin-1-ylmethyl}-benzoic acid methyl ester
Show/Hide
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C32H30N4O6
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1
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| 1 |
IC50 = 70.3 nM
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CP0428486
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2,4,5-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C30H25F3N4O4
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1
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| 1 |
IC50 = 72.7 nM
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CP0496661
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methoxy-benzyl)-2-oxo-5-pentyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C30H36N4O5
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1
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| 1 |
IC50 = 73.6 nM
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CP0491681
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2-trifluoromethoxy-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C31H27F3N4O5
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1
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| 1 |
IC50 = 74.9 nM
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CP0262170
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4-tert-butyl-N-[5-(2-methoxyphenoxy)-2-pyrimidin-2-yl-6-(2-pyrimidin-2-yloxyethoxy)pyrimidin-4-yl]benzenesulfonamide
Show/Hide
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C31H31N7O6S
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1
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| 1 |
IC50 = 76 nM
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CP0523285
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5-Isopropyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yl]-amide
Show/Hide
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C28H27N5O6S
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1
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| 1 |
IC50 = 77 nM
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CP0405194
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(S)-[(S)-5-(3-Chloro-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C31H29ClN4O5
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1
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| 1 |
IC50 = 78.2 nM
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CP0425850
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(R)-5-(2-fluoro-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C31H29FN4O5
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1
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| 1 |
IC50 = 80.2 nM
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CP0523834
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5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[2-(toluene-4-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
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C31H35N5O7S2
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1
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| 1 |
IC50 = 81 nM
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CP0394394
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(S)-((S)-1-Cyclohexylmethyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C30H34N4O4
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1
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| 1 |
IC50 = 82 nM
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CP0193973
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2,4,6-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C30H25F3N4O4
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1
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| 1 |
IC50 = 83.6 nM
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CP0480701
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5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[2-(propane-1-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
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C27H35N5O7S2
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1
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| 1 |
IC50 = 84 nM
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CP0480971
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(S)-[(S)-5-Biphenyl-3-yl-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C37H34N4O5
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1
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| 1 |
IC50 = 86.8 nM
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CP0493450
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(S)-((S)-1-Cyclopropylmethyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C27H28N4O4
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1
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| 1 |
IC50 = 87.8 nM
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CP0130277
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(S)-[(S)-5-Biphenyl-3-yl-2-oxo-1-(2,4,6-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C36H29F3N4O4
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1
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| 1 |
IC50 = 89.8 nM
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CP0463064
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5-Isobutyl-thiophene-2-sulfonic acid {2-benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-propyl-phenoxy]-acetyl}-amide
Show/Hide
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C37H42N4O6S2
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1
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| 1 |
IC50 = 90 nM
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CP0494787
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methoxy-benzyl)-5-(3-methoxy-phenyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C32H32N4O6
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1
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| 1 |
IC50 = 94.3 nM
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CP0452000
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4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid
Show/Hide
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C29H38N2O6
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2
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| 1 |
IC50 = 98 nM
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| 2 |
Ki = 139 nM
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CP0448917
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5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
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C29H34N6O8S3
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1
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| 1 |
IC50 = 100 nM
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CP0380905
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4-tert-Butyl-N-[2-(2-hydroxymethyl-pyridin-4-yl)-5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-pyrimidin-4-yl]-benzenesulfonamide
Show/Hide
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C30H30N4O6S
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1
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| 1 |
IC50 = 100 nM
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CP0448557
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4-tert-Butyl-N-[6-(3-ethanesulfonylamino-propoxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
Show/Hide
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C30H36N6O7S2
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1
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| 1 |
IC50 = 101 nM
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CP0376893
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5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-[2-(propane-1-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
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C28H38N6O8S2
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1
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| 1 |
IC50 = 103 nM
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CP0460882
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5-Isopropyl-pyridine-2-sulfonic acid [2-cyclopropyl-6-(3-ethanesulfonylamino-propoxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-amide
Show/Hide
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C27H35N5O7S2
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1
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| 1 |
IC50 = 103 nM
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CP0449870
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(S)-[(S)-5-Cyclohexyl-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C31H36N4O5
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1
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| 1 |
IC50 = 105 nM
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CP0490406
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(2-hydroxy-ethyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C25H26N4O5
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1
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| 1 |
IC50 = 108 nM
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CP0401639
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(S)-[(S)-1-(2,4-Difluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C30H26F2N4O4
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1
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| 1 |
IC50 = 109 nM
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CP0500927
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(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(3,5-dimethyl-phenoxy)-acetic acid
Show/Hide
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C32H28Cl2N2O4
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1
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| 1 |
IC50 = 109 nM
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CP0503015
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(S)-[(S)-1-(4-Bromo-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C30H27BrN4O4
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1
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| 1 |
IC50 = 119 nM
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CP0376892
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5-Isopropyl-pyridine-2-sulfonic acid [6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-2-morpholin-4-yl-pyrimidin-4-yl]-amide
Show/Hide
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C27H36N6O8S2
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1
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| 1 |
IC50 = 122 nM
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CP0504135
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(S)-[(S)-1-(4-Chloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C30H27ClN4O4
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1
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| 1 |
IC50 = 122 nM
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CP0505980
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4-[5-(2-methoxyphenoxy)-6-[(5-propan-2-ylpyridin-2-yl)sulfonylamino]-2-pyridin-4-ylpyrimidin-4-yl]oxybut-2-ynyl N-pyridin-2-ylcarbamate
Show/Hide
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C34H31N7O7S
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1
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| 1 |
IC50 = 123 nM
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CP0423706
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N-[5-(2-methoxyphenoxy)-2-pyrimidin-2-yl-6-[2-[5-(trifluoromethyl)pyrimidin-2-yl]oxyethoxy]pyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
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C30H26F3N7O6S
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1
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| 1 |
IC50 = 145 nM
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CP0368400
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N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-amine
Show/Hide
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C28H25BrN8O6S
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1
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| 1 |
IC50 = 147 nM
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CP0441463
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(S)-[(S)-1-(2-Cyclohexyl-ethyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C31H36N4O4
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1
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| 1 |
IC50 = 153 nM
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CP0435970
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5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(butylsulfamoyl)pyrimidin-4-amine
Show/Hide
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C20H22Br2N6O4S
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1
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| 1 |
IC50 = 158 nM
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CP0395678
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N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrazin-2-ylpyrimidin-4-amine
Show/Hide
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C28H25BrN8O6S
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1
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| 1 |
IC50 = 166 nM
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CP0499894
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6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(butylsulfamoyl)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-amine
Show/Hide
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C25H27BrN8O6S
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1
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| 1 |
IC50 = 167 nM
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CP0428498
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methoxy-benzyl)-2-oxo-5-p-tolyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C32H32N4O5
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1
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| 1 |
IC50 = 181 nM
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CP0374617
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5-Isopropyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-amide
Show/Hide
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C23H24N4O6S
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1
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| 1 |
IC50 = 183 nM
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CP0193626
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
Show/Hide
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C24H24N4O4
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1
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| 1 |
IC50 = 184 nM
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CP0430304
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(S)-[(S)-1-(2-Chloro-6-fluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(3,5-dimethyl-phenoxy)-acetic acid
Show/Hide
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C32H28ClFN2O4
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1
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| 1 |
IC50 = 184 nM
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CP0435983
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N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-morpholin-4-ylpyrimidin-4-amine
Show/Hide
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C28H30BrN7O7S
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1
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| 1 |
IC50 = 192 nM
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CP0435975
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6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-N-(methylsulfamoyl)-2-pyrimidin-2-ylpyrimidin-4-amine
Show/Hide
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C22H21BrN8O6S
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1
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| 1 |
IC50 = 194 nM
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CP0486392
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4-[5-(2-methoxyphenoxy)-6-[(5-methylpyridin-2-yl)sulfonylamino]-2-morpholin-4-ylpyrimidin-4-yl]oxybut-2-ynyl N-pyridin-2-ylcarbamate
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C31H31N7O8S
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1
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| 1 |
IC50 = 197 nM
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CP0418361
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4-tert-butyl-N-[5-(2-methoxyphenoxy)-6-(4-phenylmethoxybut-2-ynoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
Show/Hide
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C36H35N5O6S
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1
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| 1 |
IC50 = 199 nM
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CP0065655
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4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide
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C27H29N5O6S
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3
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| 1 |
IC50 = 202 nM
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| 2 |
IC50 = 280 nM
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| 3 |
Ki = 80 nM
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CP0435980
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N-[5-(2-methoxyphenoxy)-6-[2-(5-methoxypyrimidin-2-yl)oxyethoxy]-2-pyrimidin-2-ylpyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
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C30H29N7O7S
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1
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| 1 |
IC50 = 202 nM
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CP0383955
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5-Isopropyl-pyridine-2-sulfonic acid [2-(2-hydroxymethyl-pyridin-4-yl)-5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-pyrimidin-4-yl]-amide
Show/Hide
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C28H27N5O6S
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1
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| 1 |
IC50 = 205 nM
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CP0505716
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Butyl-carbamic acid 4-[5-(2-methoxy-phenoxy)-6-(5-methyl-pyridine-2-sulfonylamino)-2-morpholin-4-yl-pyrimidin-4-yloxy]-but-2-ynyl ester
Show/Hide
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C30H36N6O8S
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1
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| 1 |
IC50 = 207 nM
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CP0435966
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6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-chloro-5-methoxyphenoxy)-N-(propylsulfamoyl)pyrimidin-4-amine
Show/Hide
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C20H22BrClN6O6S
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1
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| 1 |
IC50 = 208 nM
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CP0559865
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2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl(methylcarboxamido)methylcarboxamido]-3-methylbutylcarboxamido}ethylcarboxamido)-2-methylbutylcarboxamido]-2-methylbutylcarboxamido}-3-(1H-3-indolyl)propanoic acid
Show/Hide
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C52H67N7O10
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1
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| 1 |
IC50 = 210 nM
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CP0464147
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(2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-[(butyl-propyl-carbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid
Show/Hide
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C28H36N2O6
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1
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| 1 |
IC50 = 211 nM
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CP0249256
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N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
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C29H26BrN7O6S
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1
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| 1 |
IC50 = 216 nM
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CP0494074
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2-(1,3-benzodioxol-5-yl)-2-(6-chloro-1-methylindol-3-yl)-N-(2-methoxy-4-methylphenyl)sulfonylacetamide
Show/Hide
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C26H23ClN2O6S
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1
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| 1 |
IC50 = 217 nM
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CP0494075
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2-(1,3-benzodioxol-5-yl)-2-(6-fluoro-1-methylindol-3-yl)-N-(2-methoxy-4-methylphenyl)sulfonylacetamide
Show/Hide
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C26H23FN2O6S
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1
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| 1 |
IC50 = 219 nM
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CP0498131
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5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-[2-(1H-tetrazol-5-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide
Show/Hide
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C28H25N9O5S
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1
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| 1 |
IC50 = 221 nM
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CP0502302
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Benzo[1,3]dioxol-5-yl-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-acetic acid
Show/Hide
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C32H37N3O5
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1
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| 1 |
IC50 = 230 nM
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CP0503871
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4-[5-(2-methoxyphenoxy)-6-[(5-propan-2-ylpyridin-2-yl)sulfonylamino]-2-pyridin-4-ylpyrimidin-4-yl]oxybut-2-ynyl N-pyrazin-2-ylcarbamate
Show/Hide
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C33H30N8O7S
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1
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| 1 |
IC50 = 236 nM
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CP0398618
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4-tert-Butyl-N-{5-(2-methoxy-phenoxy)-2-[2-(5-oxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl)-pyridin-4-yl]-6-prop-2-ynyloxy-pyrimidin-4-yl}-benzenesulfonamide
Show/Hide
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C31H28N6O7S
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1
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| 1 |
IC50 = 238 nM
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CP0514035
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ethyl 3-[1-(1,3-benzodioxol-5-yl)-2-[(2-methoxy-4-methylphenyl)sulfonylamino]-2-oxoethyl]-1-methylindole-6-carboxylate
Show/Hide
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C29H28N2O8S
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1
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| 1 |
IC50 = 240 nM
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CP0428670
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4-[5-(2-methoxyphenoxy)-6-[(5-methylpyridin-2-yl)sulfonylamino]-2-morpholin-4-ylpyrimidin-4-yl]oxybut-2-ynyl N-pyrazin-2-ylcarbamate
Show/Hide
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C30H30N8O8S
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1
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| 1 |
IC50 = 241 nM
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CP0375999
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methoxy-benzyl)-2-oxo-5-(3-trifluoromethyl-phenyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C32H29F3N4O5
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1
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| 1 |
IC50 = 241 nM
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CP0391251
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2-(1,3-benzodioxol-5-yl)-2-[6-(hydroxymethyl)-1-methylindol-3-yl]-N-(2-methoxy-4-methylphenyl)sulfonylacetamide
Show/Hide
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C27H26N2O7S
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1
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| 1 |
IC50 = 245 nM
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CP0439360
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-1-methyl-6-phenyl-5,6-dihydro-4H-2,3,5,10b-tetraaza-benzo[e]azulen-6-yl)-acetic acid
Show/Hide
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C25H24N6O3
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1
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| 1 |
IC50 = 250 nM
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CP0492667
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4-{(S)-5-[(S)-Carboxy-(4,6-dimethyl-pyrimidin-2-yloxy)-methyl]-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[e][1,4]diazepin-1-yl}-butyric acid
Show/Hide
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C27H28N4O6
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1
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| 1 |
IC50 = 253 nM
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CP0423167
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4-tert-Butyl-N-{5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-[2-(5-thioxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl)-pyridin-4-yl]-pyrimidin-4-yl}-benzenesulfonamide
Show/Hide
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C31H28N6O6S2
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1
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| 1 |
IC50 = 258 nM
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CP0918803
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(S)-6-[(S)-Carboxy-(4,6-dimethyl-pyrimidin-2-yloxy)-methyl]-6-phenyl-5,6-dihydro-4H-2,3,5,10b-tetraaza-benzo[e]azulene-1-carboxylic acid
Show/Hide
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C26H24N6O5
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1
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| 1 |
IC50 = 261 nM
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CP0146575
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3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-4-methyl-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide
Show/Hide
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C27H25N3O7S
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1
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| 1 |
IC50 = 275 nM
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CP0481093
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5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-[2-(5-oxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl)-pyridin-4-yl]-6-prop-2-ynyloxy-pyrimidin-4-yl}-amide
Show/Hide
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C29H25N7O7S
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1
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| 1 |
IC50 = 294 nM
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CP0448112
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4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-pyridin-4-yl-pyrimidin-4-yl]-benzenesulfonamide
Show/Hide
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C29H28N4O5S
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1
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| 1 |
IC50 = 295 nM
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CP0460857
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4-[4-(tert-butyl)phenylsulfonamido]-2-cyclopropyl-5-(2-methoxyphenoxy)-6-[2-(4-methylphenylsulfonamido)ethoxy]pyrimidine
Show/Hide
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C33H38N4O7S2
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1
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| 1 |
IC50 = 299 nM
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CP0486689
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6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-N-(propylsulfamoyl)-2-pyrimidin-2-ylpyrimidin-4-amine
Show/Hide
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C24H25BrN8O6S
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1
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| 1 |
IC50 = 322 nM
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CP0402103
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4-tert-Butyl-N-[2-cyclopropyl-6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-benzenesulfonamide
Show/Hide
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C28H36N4O7S2
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1
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| 1 |
IC50 = 323 nM
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CP0477080
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N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
Show/Hide
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C27H22BrN7O6S
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1
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| 1 |
IC50 = 341 nM
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CP0265839
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3-[(1S)-1-(1,3-benzodioxol-5-yl)-2-[(2-methoxy-4-methylphenyl)sulfonylamino]-2-oxoethyl]-1-methylindole-6-carboxylic acid
Show/Hide
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C27H24N2O8S
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2
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| 1 |
IC50 = 347 nM
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| 2 |
Ki = 1459 nM
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CP0490210
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5-Methyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-2-(3,4,5-trimethoxy-phenyl)-pyrimidin-4-yl]-amide
Show/Hide
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C32H33N5O10S3
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1
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| 1 |
IC50 = 351 nM
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CP0428778
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5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-[2-(5-thioxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide
Show/Hide
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C29H25N7O6S2
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1
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| 1 |
IC50 = 366 nM
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CP0430885
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N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-3-phenylpropane-1-sulfonamide
Show/Hide
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C30H28BrN7O6S
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1
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| 1 |
IC50 = 377 nM
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CP0415199
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ACT-064992
Show/Hide
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C19H20Br2N6O4S
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1
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| 1 |
IC50 = 391 nM
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CP0510035
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(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(3,5-dimethoxy-phenoxy)-acetic acid
Show/Hide
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C32H28Cl2N2O6
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1
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| 1 |
IC50 = 392 nM
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CP0395394
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(2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-dipropylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid
Show/Hide
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C27H34N2O6
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1
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| 1 |
IC50 = 397 nM
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CP0452839
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5-Isopropyl-pyridine-2-sulfonic acid [2-cyclopropyl-6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-amide
Show/Hide
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C26H33N5O7S2
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1
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| 1 |
IC50 = 397 nM
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CP0298518
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3-[1-Benzo[1,3]dioxol-5-yl-2-(2-ethoxy-4-methyl-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide
Show/Hide
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C28H27N3O7S
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1
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| 1 |
IC50 = 397 nM
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CP0404479
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5-Isobutyl-3H-1lambda*4*-thiophene-2-sulfonic acid {2-benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-acetyl}-amide
Show/Hide
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C40H48N4O6S2
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1
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| 1 |
IC50 = 420 nM
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CP0522256
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4-[4-(tert-butyl)phenylsulfonamido]-5-(2-methoxyphenoxy)-6-[2-(4-methylphenylsulfonamido)ethoxy]-2-(2-pyrimidinyl)pyrimidine
Show/Hide
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C34H36N6O7S2
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1
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| 1 |
IC50 = 420 nM
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CP0441509
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2-(1,3-benzodioxol-5-yl)-2-(6-cyano-1-methylindol-3-yl)-N-(2-methoxy-4-methylphenyl)sulfonylacetamide
Show/Hide
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C27H23N3O6S
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1
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| 1 |
IC50 = 421 nM
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CP0395680
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N-[6-[2-(5-cyclopropylpyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
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C32H31N7O6S
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1
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| 1 |
IC50 = 424 nM
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CP0249832
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N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(4-methylphenyl)pyrimidin-4-amine
Show/Hide
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C24H23BrN6O4S
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1
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| 1 |
IC50 = 441 nM
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CP0421504
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5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
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C27H30N6O8S3
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1
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| 1 |
IC50 = 447 nM
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CP0435982
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N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(3-methoxyphenoxy)pyrimidin-4-amine
Show/Hide
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C24H23BrN6O6S
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1
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| 1 |
IC50 = 457 nM
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CP0453935
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4-[[benzyl(methyl)sulfamoyl]amino]-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidine
Show/Hide
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C29H27BrN8O6S
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1
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| 1 |
IC50 = 457 nM
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CP0395679
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N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]ethanesulfonamide
Show/Hide
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C23H22BrN7O6S
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1
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| 1 |
IC50 = 460 nM
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CP0446205
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N-(benzylsulfamoyl)-5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]pyrimidin-4-amine
Show/Hide
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C23H20Br2N6O4S
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1
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| 1 |
IC50 = 461 nM
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CP0486691
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N-[6-[2-(5-chloropyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
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C29H26ClN7O6S
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1
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| 1 |
IC50 = 461 nM
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CP0362696
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N-[5-(2-methoxyphenoxy)-2-pyrimidin-2-yl-6-(2-pyrimidin-2-yloxyethoxy)pyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
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C29H27N7O6S
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1
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| 1 |
IC50 = 465 nM
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CP0511495
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6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(3-methoxyphenoxy)-N-(propylsulfamoyl)pyrimidin-4-amine
Show/Hide
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C20H23BrN6O6S
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1
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| 1 |
IC50 = 468 nM
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CP0428535
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(S)-(4,6-Dimethoxy-pyrimidin-2-yloxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
Show/Hide
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C24H24N4O6
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1
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| 1 |
IC50 = 473 nM
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CP0460977
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N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(4-chlorophenyl)pyrimidin-4-amine
Show/Hide
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C23H20BrClN6O4S
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1
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| 1 |
IC50 = 506 nM
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CP0149984
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N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)pyrimidin-4-amine
Show/Hide
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C24H23BrN6O6S
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1
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| 1 |
IC50 = 525 nM
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CP0401595
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(S)-((S)-1-Biphenyl-4-ylmethyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C36H32N4O4
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1
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| 1 |
IC50 = 534 nM
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CP0399704
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3H-1lambda*4*-Thiophene-2-sulfonic acid {2-benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-acetyl}-amide
Show/Hide
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C36H40N4O6S2
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1
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| 1 |
IC50 = 540 nM
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CP0249829
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N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]butane-1-sulfonamide
Show/Hide
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C25H26BrN7O6S
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1
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| 1 |
IC50 = 552 nM
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CP0446095
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N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-2-(2-methoxyethoxy)-5-(2-methoxyphenoxy)pyrimidin-4-amine
Show/Hide
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C27H29BrN6O8S
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1
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| 1 |
IC50 = 554 nM
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CP0401635
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(S)-((S)-1-Carboxymethyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C25H24N4O6
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1
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| 1 |
IC50 = 558 nM
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CP0460978
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N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyridin-4-ylpyrimidin-4-amine
Show/Hide
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C29H26BrN7O6S
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1
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| 1 |
IC50 = 561 nM
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CP0095826
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(S)-(3,5-Dimethyl-phenoxy)-[(S)-2-oxo-5-phenyl-1-(2,4,6-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C32H27F3N2O4
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1
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| 1 |
IC50 = 565 nM
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CP0486690
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N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]propane-1-sulfonamide
Show/Hide
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C24H24BrN7O6S
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1
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| 1 |
IC50 = 566 nM
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CP0405870
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2-[4-[[2-(1,3-benzodioxol-5-yl)-2-(6-carbamoyl-1-methylindol-3-yl)acetyl]sulfamoyl]phenyl]acetic acid
Show/Hide
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C27H23N3O8S
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1
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| 1 |
IC50 = 574 nM
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CP0392962
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(2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-1-propylcarbamoylmethyl-pyrrolidine-3-carboxylic acid
Show/Hide
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C24H28N2O6
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1
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| 1 |
IC50 = 579 nM
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CP0448946
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4-[5-(2-methoxyphenoxy)-6-[(5-methylpyridin-2-yl)sulfonylamino]-2-morpholin-4-ylpyrimidin-4-yl]oxybut-2-ynyl N-phenylcarbamate
Show/Hide
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C32H32N6O8S
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1
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| 1 |
IC50 = 589 nM
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CP0280764
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(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-5-guanidino-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid
Show/Hide
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C50H66N10O10
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1
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| 1 |
IC50 = 590 nM
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CP0503872
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4-[5-(2-methoxyphenoxy)-6-[(5-methylpyridin-2-yl)sulfonylamino]-2-morpholin-4-ylpyrimidin-4-yl]oxybut-2-ynyl N-cyclohexylcarbamate
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C32H38N6O8S
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1
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| 1 |
IC50 = 603 nM
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CP0399397
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5-Methyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-morpholin-4-yl-pyrimidin-4-yl]-amide
Show/Hide
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C25H27N5O7S
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1
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| 1 |
IC50 = 612 nM
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CP0405869
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3-[1-(1,3-benzodioxol-5-yl)-2-[(2-methoxy-4-methylphenyl)sulfonylamino]-2-oxoethyl]-1-methylindole-6-carboxylic acid
Show/Hide
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C27H24N2O8S
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1
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| 1 |
IC50 = 650 nM
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CP0384710
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(S)-(4,6-Diethyl-pyrimidin-2-yloxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
Show/Hide
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C26H28N4O4
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1
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| 1 |
IC50 = 654 nM
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CP0423735
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6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(ethylsulfamoyl)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-amine
Show/Hide
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C23H23BrN8O6S
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1
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| 1 |
IC50 = 655 nM
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CP0496417
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4-[5-(2-methoxyphenoxy)-6-[(5-methylpyridin-2-yl)sulfonylamino]-2-morpholin-4-ylpyrimidin-4-yl]oxybut-2-ynyl N-pyridin-4-ylcarbamate
Show/Hide
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C31H31N7O8S
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1
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| 1 |
IC50 = 656 nM
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CP0076043
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(2S)-2-(1,3-benzodioxol-5-yl)-2-[6-(hydroxymethyl)-1-methylindol-3-yl]-N-(2-methoxy-4-methylphenyl)sulfonylacetamide
Show/Hide
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C27H26N2O7S
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2
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| 1 |
IC50 = 683 nM
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| 2 |
Ki = 1503 nM
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CP0455422
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(S)-6-[(S)-Carboxy-(4,6-dimethyl-pyrimidin-2-yloxy)-methyl]-1-methyl-6-phenyl-5,6-dihydro-4H-2,5,10b-triaza-benzo[e]azulene-3-carboxylic acid
Show/Hide
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C27H25N5O5
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1
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| 1 |
IC50 = 711 nM
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CP0476536
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N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-chloro-5-methoxyphenoxy)pyrimidin-4-amine
Show/Hide
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C24H22BrClN6O6S
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1
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| 1 |
IC50 = 712 nM
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CP0504757
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(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(2-morpholin-4-yl-ethyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
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C29H33N5O5
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1
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| 1 |
IC50 = 743 nM
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CP0502157
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4-tert-Butyl-N-[6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-benzenesulfonamide
Show/Hide
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C25H27N3O6S
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1
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| 1 |
IC50 = 744 nM
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CP0418845
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(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-m-tolyloxy-acetic acid
Show/Hide
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C31H26Cl2N2O4
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1
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| 1 |
IC50 = 745 nM
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CP0383292
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5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-prop-2-ynyloxy-pyrimidin-4-yl]-amide
Show/Hide
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C26H29N5O6S
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1
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| 1 |
IC50 = 746 nM
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CP0481012
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(S)-[(S)-5-(3,5-Dimethyl-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C33H34N4O5
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1
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| 1 |
IC50 = 761 nM
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CP0435981
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6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(4-chlorophenyl)-N-(propylsulfamoyl)pyrimidin-4-amine
Show/Hide
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C19H20BrClN6O4S
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1
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| 1 |
IC50 = 784 nM
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CP0503424
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N-(benzenesulfonyl)-2-(1,3-benzodioxol-5-yl)-2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]-2,6-dipropylphenoxy]acetamide
Show/Hide
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C38H42N4O6S
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1
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| 1 |
IC50 = 800 nM
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CP0453518
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5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(methylsulfamoyl)pyrimidin-4-amine
Show/Hide
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C17H16Br2N6O4S
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1
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| 1 |
IC50 = 812 nM
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CP0419387
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5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-pyridin-4-yl-pyrimidin-4-yl]-amide
Show/Hide
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C27H25N5O5S
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1
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| 1 |
IC50 = 823 nM
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CP0430883
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5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(ethylsulfamoyl)pyrimidin-4-amine
Show/Hide
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C18H18Br2N6O4S
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1
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| 1 |
IC50 = 830 nM
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CP0419746
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4-tert-Butyl-N-[6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
Show/Hide
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C29H29N5O6S
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1
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| 1 |
IC50 = 832 nM
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CP0454815
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4-tert-Butyl-N-[6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
Show/Hide
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C29H34N6O7S2
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1
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| 1 |
IC50 = 873 nM
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CP0112005
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(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-phenyl-ethyl)-succinamic acid
Show/Hide
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C53H63N7O10
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1
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| 1 |
IC50 = 900 nM
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CP0428466
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4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-pyrazin-2-yl-pyrimidin-4-yl]-benzenesulfonamide
Show/Hide
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C28H27N5O5S
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1
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| 1 |
IC50 = 903 nM
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CP0396129
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2-(6-acetyl-1-methylindol-3-yl)-2-(1,3-benzodioxol-5-yl)-N-(2-methoxy-4-methylphenyl)sulfonylacetamide
Show/Hide
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C28H26N2O7S
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1
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| 1 |
IC50 = 906 nM
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CP0449640
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4-[5-(2-methoxyphenoxy)-6-[(5-methylpyridin-2-yl)sulfonylamino]-2-morpholin-4-ylpyrimidin-4-yl]oxybut-2-ynyl N-pyridin-3-ylcarbamate
Show/Hide
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C31H31N7O8S
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1
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| 1 |
IC50 = 920 nM
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CP0454669
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5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-[2-(propane-1-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
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C26H34N6O8S2
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1
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| 1 |
IC50 = 931 nM
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CP0416615
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1-Dibutylcarbamoylmethyl-4-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-2-(4-ethyl-3-fluoro-phenyl)-pyrrolidine-3-carboxylic acid
Show/Hide
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C31H41FN2O5
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1
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| 1 |
IC50 = 950 nM
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CP0094665
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(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid
Show/Hide
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C50H65N7O10
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1
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| 1 |
IC50 = 960 nM
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CP0504787
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(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-p-tolyloxy-acetic acid
Show/Hide
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C31H26Cl2N2O4
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1
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| 1 |
IC50 = 966 nM
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CP0505932
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4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-(4-phenoxy-but-2-ynyloxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
Show/Hide
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C35H33N5O6S
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1
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| 1 |
IC50 = 973 nM
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CP0430244
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5-(4-bromophenyl)-4-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-6-(sulfamoylamino)pyrimidine
Show/Hide
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C16H14Br2N6O4S
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1
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| 1 |
IC50 = 987 nM
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CP0448951
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5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-[2-(1H-tetrazol-5-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide
Show/Hide
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C26H21N9O5S
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1
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| 1 |
IC50 = 1030 nM
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CP0486390
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4-[6-[(4-tert-butylphenyl)sulfonylamino]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]oxybut-2-ynyl N-pyridin-2-ylcarbamate
Show/Hide
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C35H33N7O7S
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1
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| 1 |
IC50 = 1060 nM
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CP0436711
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(2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-[(butyl-methyl-carbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid
Show/Hide
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C26H32N2O6
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1
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| 1 |
IC50 = 1080 nM
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CP0547785
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N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-2-cyclopropyl-5-(2-methoxyphenoxy)pyrimidin-4-amine
Show/Hide
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C27H27BrN6O6S
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1
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| 1 |
IC50 = 1082 nM
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CP0467200
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N-[4-(3,5-dioxohexyl)phenyl]-3-[2-[2-[2-[2-[methyl-[[5-(1,3-oxazol-2-yl)-2-[2-(1,2-oxazol-5-ylsulfamoyl)phenyl]phenyl]methyl]amino]-2-oxoethoxy]ethoxy]ethoxy]ethoxy]propanamide
Show/Hide
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C43H49N5O12S
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1
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| 1 |
IC50 = 1110 nM
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CP0271450
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N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
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C25H25N5O6S
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1
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| 1 |
IC50 = 1131 nM
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CP0452881
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4-tert-Butyl-N-[6-(4-methoxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
Show/Hide
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C30H31N5O6S
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1
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| 1 |
IC50 = 1140 nM
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CP0535041
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2-(1,3-benzodioxol-5-yl)-2-[6-(methoxymethyl)-1-methylindol-3-yl]-N-(2-methoxy-4-methylphenyl)sulfonylacetamide
Show/Hide
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C28H28N2O7S
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1
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| 1 |
IC50 = 1140 nM
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CP0453936
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N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]methanesulfonamide
Show/Hide
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C22H20BrN7O6S
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1
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| 1 |
IC50 = 1146 nM
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CP0501088
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4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
Show/Hide
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C28H27N5O5S
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1
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| 1 |
IC50 = 1190 nM
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CP0002228
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(S)-2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid
Show/Hide
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C22H22N2O4
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1
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| 1 |
IC50 = 1190 nM
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CP0420943
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2-(1,3-benzodioxol-5-yl)-2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]-2,6-dipropylphenoxy]-N-methylsulfonylacetamide
Show/Hide
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C33H40N4O6S
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1
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| 1 |
IC50 = 1200 nM
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CP0430884
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N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(4-ethylphenyl)pyrimidin-4-amine
Show/Hide
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C25H25BrN6O4S
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1
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| 1 |
IC50 = 1264 nM
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CP0500243
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2-(1,3-benzodioxol-5-yl)-2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]-2,6-dipropylphenoxy]-N-(4-propan-2-ylphenyl)sulfonylacetamide
Show/Hide
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C41H48N4O6S
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1
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| 1 |
IC50 = 1300 nM
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CP0376120
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4-[6-[(4-tert-butylphenyl)sulfonylamino]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]oxybut-2-ynyl N-pyrazin-2-ylcarbamate
Show/Hide
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C34H32N8O7S
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1
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| 1 |
IC50 = 1400 nM
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CP0425842
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(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(3-methoxy-phenoxy)-acetic acid
Show/Hide
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C31H26Cl2N2O5
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1
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| 1 |
IC50 = 1470 nM
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CP0415197
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N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]morpholine-4-sulfonamide
Show/Hide
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C25H25BrN8O7S
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1
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| 1 |
IC50 = 1474 nM
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CP0453703
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5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(cyclopropylsulfamoyl)pyrimidin-4-amine
Show/Hide
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C19H18Br2N6O4S
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1
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| 1 |
IC50 = 1474 nM
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CP0415198
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N-[5-(2-methoxyphenoxy)-6-[2-(5-methylpyrimidin-2-yl)oxyethoxy]-2-pyrimidin-2-ylpyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
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C30H29N7O6S
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1
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| 1 |
IC50 = 1501 nM
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CP0436737
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5-Methyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yl]-amide
Show/Hide
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C26H23N5O6S
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1
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| 1 |
IC50 = 1520 nM
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CP0454811
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5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-pyridin-4-yl-6-[2-(toluene-4-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
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C31H30N6O7S2
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1
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| 1 |
IC50 = 1537 nM
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CP0430986
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Benzo[1,3]dioxol-5-yl-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-propyl-phenoxy]-acetic acid
Show/Hide
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C29H31N3O5
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1
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| 1 |
IC50 = 1600 nM
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CP0507739
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5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-[2-(5-thioxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide
Show/Hide
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C27H21N7O6S2
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1
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| 1 |
IC50 = 1670 nM
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CP0453937
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N-[5-(2-methoxyphenoxy)-2-pyrimidin-2-yl-6-(2-pyrimidin-2-yloxyethoxy)pyrimidin-4-yl]methanesulfonamide
Show/Hide
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C22H21N7O6S
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1
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| 1 |
IC50 = 1765 nM
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CP0430432
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(S)-[(S)-1-(2-Dimethylamino-ethyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
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C27H31N5O4
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1
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| 1 |
IC50 = 1780 nM
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CP0201357
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(S)-4-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-4-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butylcarbamoyl)-butyric acid
Show/Hide
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C51H67N7O10
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1
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| 1 |
IC50 = 1800 nM
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CP0494782
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(S)-((S)-7-Chloro-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(3,5-dimethoxy-phenoxy)-acetic acid
Show/Hide
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C26H25ClN2O6
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1
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| 1 |
IC50 = 1810 nM
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CP0471758
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2-(1,3-benzodioxol-5-yl)-2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]-2,6-dipropylphenoxy]-N-propan-2-ylsulfonylacetamide
Show/Hide
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C35H44N4O6S
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1
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| 1 |
IC50 = 1900 nM
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CP0427898
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N-[4-(3,5-dioxohexyl)phenyl]-3-[2-[2-[2-[2-[4-[2-[methyl-[[5-(1,3-oxazol-2-yl)-2-[2-(1,2-oxazol-5-ylsulfamoyl)phenyl]phenyl]methyl]amino]-2-oxoethyl]phenoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanamide
Show/Hide
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C51H57N5O13S
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1
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| 1 |
IC50 = 1910 nM
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CP0372935
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5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-[2,2']bipyrimidinyl-4-yl]-amide
Show/Hide
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C26H24N6O5S
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1
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| 1 |
IC50 = 1950 nM
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CP0439373
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5-Isopropyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-amide
Show/Hide
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C27H26N6O6S
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1
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| 1 |
IC50 = 2030 nM
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CP0510963
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4-tert-butyl-N-[5-(2-methoxyphenoxy)-6-prop-2-enoxy-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
Show/Hide
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C28H29N5O5S
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1
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| 1 |
IC50 = 2085 nM
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CP0372750
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5-Methyl-pyridine-2-sulfonic acid {2-benzo[1,3]dioxol-5-ylmethyl-5-(2-methoxy-phenoxy)-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
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C31H29N5O9S3
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1
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| 1 |
IC50 = 2110 nM
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CP0394293
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4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-pent-2-ynyloxy-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
Show/Hide
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C30H31N5O5S
|
1
|
| 1 |
IC50 = 2280 nM
|
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CP0491713
|
N-[5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]pyrimidin-4-yl]butane-1-sulfonamide
Show/Hide
|
C20H21Br2N5O4S
|
1
|
| 1 |
IC50 = 2424 nM
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CP0482381
|
N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(4-propan-2-ylphenyl)pyrimidin-4-amine
Show/Hide
|
C26H27BrN6O4S
|
1
|
| 1 |
IC50 = 2474 nM
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CP0453934
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N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-2-methoxy-5-(2-methoxyphenoxy)pyrimidin-4-amine
Show/Hide
|
C25H25BrN6O7S
|
1
|
| 1 |
IC50 = 2490 nM
|
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CP0509179
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5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-[2-(5-oxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl)-pyridin-4-yl]-6-prop-2-ynyloxy-pyrimidin-4-yl}-amide
Show/Hide
|
C27H21N7O7S
|
1
|
| 1 |
IC50 = 2500 nM
|
|
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CP0480993
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5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-pyrazin-2-yl-pyrimidin-4-yl]-amide
Show/Hide
|
C26H24N6O5S
|
1
|
| 1 |
IC50 = 2620 nM
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CP0328005
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(2S,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(2,2-dimethyl-pentyl)-pyrrolidine-3-carboxylic acid
Show/Hide
|
C29H46N2O5
|
1
|
| 1 |
IC50 = 2800 nM
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CP0453962
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N-[5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]pyrimidin-4-yl]morpholine-4-sulfonamide
Show/Hide
|
C20H20Br2N6O5S
|
1
|
| 1 |
IC50 = 2829 nM
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|
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CP0391670
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5-Methyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-methyl-pyrimidin-4-yl]-amide
Show/Hide
|
C22H22N4O6S
|
1
|
| 1 |
IC50 = 2880 nM
|
|
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CP0423204
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4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-pent-2-enyloxy-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
Show/Hide
|
C30H33N5O5S
|
1
|
| 1 |
IC50 = 2970 nM
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CP0429524
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1-Dibutylcarbamoylmethyl-4-(2,3-dihydro-benzofuran-5-yl)-2-(4-ethyl-3-fluoro-phenyl)-pyrrolidine-3-carboxylic acid
Show/Hide
|
C31H41FN2O4
|
1
|
| 1 |
IC50 = 3050 nM
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|
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CP0430880
|
N-[5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]pyrimidin-4-yl]propane-1-sulfonamide
Show/Hide
|
C19H19Br2N5O4S
|
1
|
| 1 |
IC50 = 3058 nM
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|
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CP0495473
|
(S)-(3-Chloro-phenoxy)-[(S)-1-(2,6-dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C30H23Cl3N2O4
|
1
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| 1 |
IC50 = 3150 nM
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|
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CP0448950
|
4-tert-Butyl-N-[6-but-2-ynyloxy-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
Show/Hide
|
C29H29N5O5S
|
1
|
| 1 |
IC50 = 3169 nM
|
|
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CP0523284
|
N-[6-[(E)-but-2-enoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-4-tert-butylbenzenesulfonamide
Show/Hide
|
C29H31N5O5S
|
1
|
| 1 |
IC50 = 3330 nM
|
|
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CP0460979
|
N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-1-phenylmethanesulfonamide
Show/Hide
|
C28H24BrN7O6S
|
1
|
| 1 |
IC50 = 3479 nM
|
|
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CP0502821
|
4-{(S)-5-[(S)-Carboxy-(4,6-dimethyl-pyrimidin-2-yloxy)-methyl]-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[e][1,4]diazepin-1-ylmethyl}-benzoic acid
Show/Hide
|
C31H28N4O6
|
1
|
| 1 |
IC50 = 3530 nM
|
|
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CP0445446
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-5-phenyl-2,3,4,5-tetrahydro-benzo[f][1,4]oxazepin-5-yl)-acetic acid
Show/Hide
|
C23H23N3O4
|
1
|
| 1 |
IC50 = 3640 nM
|
|
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CP0437101
|
5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-pyridin-4-yl-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
|
C28H26N6O7S3
|
1
|
| 1 |
IC50 = 3676 nM
|
|
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CP0419386
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(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-phenoxy-acetic acid
Show/Hide
|
C30H24Cl2N2O4
|
1
|
| 1 |
IC50 = 3700 nM
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|
|
|
CP0432527
|
Ac-bhg-F-N-Y-Y-W
Show/Hide
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C61H62N8O11
|
1
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| 1 |
IC50 = 4300 nM
|
|
|
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CP0320424
|
(S)-3-[(S)-2-((S)-2-Benzoylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid
Show/Hide
|
C55H67N7O10
|
1
|
| 1 |
IC50 = 4400 nM
|
|
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CP0485190
|
N-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[3-[4-(3,5-dioxohexyl)anilino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-N'-methyl-N'-[[5-(1,3-oxazol-2-yl)-2-[2-(1,2-oxazol-5-ylsulfamoyl)phenyl]phenyl]methyl]pentanediamide
Show/Hide
|
C62H86N6O20S
|
1
|
| 1 |
IC50 = 4510 nM
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|
|
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CP0436708
|
(2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-1-[(methyl-propyl-carbamoyl)-methyl]-pyrrolidine-3-carboxylic acid
Show/Hide
|
C25H30N2O6
|
1
|
| 1 |
IC50 = 4570 nM
|
|
|
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CP0405736
|
5-Methyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-pyridin-4-yl-pyrimidin-4-yl]-amide
Show/Hide
|
C25H21N5O5S
|
1
|
| 1 |
IC50 = 4580 nM
|
|
|
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CP0421545
|
5-Methyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[2-(propane-1-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
|
C25H31N5O7S2
|
1
|
| 1 |
IC50 = 4670 nM
|
|
|
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CP0501765
|
3-{2-[2-(2-{2-[2-(2-{2-[4-(3,5-dioxo-hexyl)-phenylcarbamoyl]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-N-[2'-(isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-N-methyl-propionamide
Show/Hide
|
C50H63N5O15S
|
1
|
| 1 |
IC50 = 4690 nM
|
|
|
|
CP0467199
|
3-[4-[2-[2-[2-[2-[3-[4-(3,5-dioxohexyl)anilino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]phenyl]-N-methyl-N-[[5-(1,3-oxazol-2-yl)-2-[2-(1,2-oxazol-5-ylsulfamoyl)phenyl]phenyl]methyl]propanamide
Show/Hide
|
C52H59N5O13S
|
1
|
| 1 |
IC50 = 4920 nM
|
|
|
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CP0547780
|
N-(benzylsulfamoyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-phenylpyrimidin-4-amine
Show/Hide
|
C23H21BrN6O4S
|
1
|
| 1 |
IC50 = 5067 nM
|
|
|
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CP0477051
|
4-[[benzyl(methyl)sulfamoyl]amino]-5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]pyrimidine
Show/Hide
|
C24H22Br2N6O4S
|
1
|
| 1 |
IC50 = 5208 nM
|
|
|
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CP0501127
|
5-Methyl-pyridine-2-sulfonic acid [6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yl]-amide
Show/Hide
|
C26H28N6O7S2
|
1
|
| 1 |
IC50 = 5402 nM
|
|
|
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CP0456960
|
(S)-((S)-8-Chloro-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(3,5-dimethoxy-phenoxy)-acetic acid
Show/Hide
|
C26H25ClN2O6
|
1
|
| 1 |
IC50 = 5600 nM
|
|
|
|
CP0376442
|
5-Methyl-pyridine-2-sulfonic acid [2-cyclopropyl-6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-amide
Show/Hide
|
C24H29N5O7S2
|
1
|
| 1 |
IC50 = 5660 nM
|
|
|
|
CP0048328
|
(3S)-4-[[(2S,3S)-1-[[(2S,3S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-[[(2S)-2-[[(2S)-3,3-diphenyl-2-(tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene-2-carbonylamino)propanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoic acid
Show/Hide
|
C64H75N7O10
|
1
|
| 1 |
IC50 = 5900 nM
|
|
|
|
CP0530289
|
N,3,3-trimethyl-N-[[5-(1,3-oxazol-2-yl)-2-[2-(1,2-oxazol-5-ylsulfamoyl)phenyl]phenyl]methyl]butanamide
Show/Hide
|
C26H28N4O5S
|
1
|
| 1 |
IC50 = 6003 nM
|
|
|
|
CP0401606
|
(S)-(3,5-Dimethoxy-phenoxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
Show/Hide
|
C26H26N2O6
|
1
|
| 1 |
IC50 = 6270 nM
|
|
|
|
CP0381051
|
Ac-W-F-F-N-Y-Y-W
Show/Hide
|
C63H65N9O11
|
1
|
| 1 |
IC50 = 7600 nM
|
|
|
|
CP0453075
|
(S)-(3,5-Dimethoxy-phenoxy)-((S)-8-methoxy-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
Show/Hide
|
C27H28N2O7
|
1
|
| 1 |
IC50 = 7780 nM
|
|
|
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CP0448403
|
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[c]azepin-1-yl)-acetic acid
Show/Hide
|
C24H25N3O3
|
1
|
| 1 |
IC50 = 7840 nM
|
|
|
|
CP0430276
|
(S)-((S)-7,8-Dimethoxy-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(3,5-dimethoxy-phenoxy)-acetic acid
Show/Hide
|
C28H30N2O8
|
1
|
| 1 |
IC50 = 8030 nM
|
|
|
|
CP0538965
|
5-Methyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide
Show/Hide
|
C26H27N5O7S3
|
1
|
| 1 |
IC50 = 8240 nM
|
|
|
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CP0453464
|
(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4-isopropyl-phenoxy)-acetic acid
Show/Hide
|
C33H30Cl2N2O4
|
1
|
| 1 |
IC50 = 8620 nM
|
|
|
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CP0436744
|
(S)-(5-Methoxy-pyrimidin-2-yloxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
Show/Hide
|
C23H22N4O5
|
1
|
| 1 |
IC50 = 9250 nM
|
|
|
|
CP0504944
|
(S)-(5-Bromo-pyrimidin-2-yloxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
Show/Hide
|
C22H19BrN4O4
|
1
|
| 1 |
IC50 = 9480 nM
|
|
|
|
CP0453938
|
N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]methanesulfonamide
Show/Hide
|
C18H19N5O6S
|
1
|
| 1 |
IC50 = 9506 nM
|
|
|
|
CP0307099
|
(S)-2-[(2S,3S)-2-((2S,3S)-2-{2-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-6-amino-hexanoylamino}-3-methyl-pentanoylamino)-3-methyl-pentanoylamino]-3-(1H-indol-3-yl)-propionic acid
Show/Hide
|
C52H72N8O8
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0449639
|
5-Methyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-amide
Show/Hide
|
C25H22N6O6S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0506671
|
5-Methyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-[2,2']bipyrimidinyl-4-yl]-amide
Show/Hide
|
C24H20N6O5S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0444716
|
N-[[5-[2-[2-[2-[3-[4-(3,5-dioxohexyl)anilino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]-2-[2-(1,2-oxazol-5-ylsulfamoyl)phenyl]phenyl]methyl]-N,3,3-trimethylbutanamide
Show/Hide
|
C44H56N4O11S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0453425
|
(S)-(2-Chloro-phenoxy)-[(S)-1-(2,6-dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid
Show/Hide
|
C30H23Cl3N2O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0472182
|
(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-o-tolyloxy-acetic acid
Show/Hide
|
C31H26Cl2N2O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0487455
|
(S)-((S)-1-Methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C22H20N4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0498629
|
(S)-((S)-1-Methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(5-methylsulfanyl-pyrimidin-2-yloxy)-acetic acid
Show/Hide
|
C23H22N4O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0502121
|
(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(2-methoxy-phenoxy)-acetic acid
Show/Hide
|
C31H26Cl2N2O5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0430877
|
N-[6-[2-(4,6-dimethoxypyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-2-phenylethanesulfonamide
Show/Hide
|
C31H31N7O8S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0449622
|
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-amino-2-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenyl)acetyl]amino]-3-phenylpropanoyl]amino]-4-oxobutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoic acid
Show/Hide
|
C59H60N8O10
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0448076
|
Ac-w-F-F-N-Y-Y-W
Show/Hide
|
C63H65N9O11
|
1
|
| 1 |
IC50 = 14000 nM
|
|
|
|
CP0393004
|
(2R)-2-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)propanoic acid
Show/Hide
|
C62H63N9O12
|
1
|
| 1 |
IC50 = 15000 nM
|
|
|
|
CP0023329
|
(2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-(2,2-dimethyl-pentyl)-4-(7-methoxy-benzo[1,3]dioxol-5-yl)-pyrrolidine-3-carboxylic acid
Show/Hide
|
C30H48N2O6
|
2
|
| 1 |
IC50 = 15400 nM
|
|
|
| 2 |
Ki = 13000 nM
|
|
|
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CP0392951
|
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[(3S,6R,12R,15S,18R,24S,27R)-18-(2-amino-2-oxoethyl)-6-[(1R)-1-hydroxyethyl]-12-(1H-imidazol-4-ylmethyl)-15-(1H-indol-3-ylmethyl)-3-methyl-2,5,8,11,14,17,20,23,26-nonaoxo-1,4,7,10,13,16,19,22,25-nonazabicyclo[25.3.0]triacontan-24-yl]acetyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-oxobutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoic acid
Show/Hide
|
C103H115N23O23
|
1
|
| 1 |
IC50 = 16000 nM
|
|
|
|
CP0356826
|
(2S,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-[2-(2-oxo-pyrrolidin-1-yl)-ethyl]-pyrrolidine-3-carboxylic acid
Show/Hide
|
C28H41N3O6
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0374942
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(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-oxobutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoic acid
Show/Hide
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C51H54N8O10
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1
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| 1 |
IC50 > 25000 nM
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CP0077943
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(2,5-Dibromo-3,4-dimethoxy-phenyl)-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-acetic acid
Show/Hide
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C33H39Br2N3O5
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1
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| 1 |
IC50 = 31000 nM
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CP0041541
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(2S,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(2-pyridin-2-yl-ethyl)-pyrrolidine-3-carboxylic acid
Show/Hide
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C29H39N3O5
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1
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| 1 |
IC50 = 32000 nM
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CP0307521
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(2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-((Z)-2,2-dimethyl-pent-3-enyl)-4-(7-methoxy-benzo[1,3]dioxol-5-yl)-pyrrolidine-3-carboxylic acid
Show/Hide
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C30H46N2O6
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1
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| 1 |
IC50 = 39700 nM
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CP0190745
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(2S,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(2-pyrazol-1-yl-ethyl)-pyrrolidine-3-carboxylic acid
Show/Hide
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C27H38N4O5
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1
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| 1 |
IC50 = 42000 nM
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CP0453219
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2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]-2-propylphenoxy]-2-phenylacetic acid
Show/Hide
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C28H31N3O3
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1
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| 1 |
IC50 = 47000 nM
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CP0352140
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(2S,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-((Z)-2,2-dimethyl-pent-3-enyl)-pyrrolidine-3-carboxylic acid
Show/Hide
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C29H44N2O5
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1
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| 1 |
IC50 = 92700 nM
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CP0493865
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5-Methyl-pyridine-2-sulfonic acid [2-(2-hydroxymethyl-pyridin-4-yl)-5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-pyrimidin-4-yl]-amide
Show/Hide
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C26H23N5O6S
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1
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| 1 |
IC50 > 1000 nM
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CP0405213
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(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(2,3-dimethyl-phenoxy)-acetic acid
Show/Hide
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C32H28Cl2N2O4
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1
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| 1 |
IC50 > 1000 nM
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CP0493469
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(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(2,5-dimethyl-phenoxy)-acetic acid
Show/Hide
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C32H28Cl2N2O4
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1
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| 1 |
IC50 > 1000 nM
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CP0156307
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CHEBI:2965
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C31H42N6O7
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1
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| 1 |
IC50 > 1000 nM
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CP0505039
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(S)-2-[(2S,3S)-2-((2S,3S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-3-phenyl-propionylamino}-3-methyl-pentanoylamino)-3-methyl-pentanoylamino]-3-(1H-indol-3-yl)-propionic acid
Show/Hide
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C55H69N7O8
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1
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| 1 |
IC50 > 1600 nM
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CP0375005
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(3R)-3-[[(2R)-1-[(2S)-2-[[(2S,3R)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[(2-aminoacetyl)amino]-4-oxobutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]acetyl]amino]-3-hydroxybutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C103H117N23O24
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1
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| 1 |
IC50 > 2500 nM
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CP0480561
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(3R)-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-[[(2R)-1-[(2S)-2-[[(2S,3R)-2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]acetyl]amino]-3-hydroxybutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-4-oxobutanoic acid
Show/Hide
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C97H108N20O21
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1
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| 1 |
IC50 > 2500 nM
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CP0494555
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2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-[2-(3,4,5-trimethoxy-phenyl)-ethoxy]-propionic acid
Show/Hide
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C32H34N2O7
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1
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| 1 |
Ki = 3.21 nM
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CP0501896
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(S)-3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
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C31H32N2O6
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1
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| 1 |
Ki = 4.75 nM
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CP0184415
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4-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethoxy]-3-propyl-benzoic acid
Show/Hide
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C28H29NO8S
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1
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| 1 |
Ki = 5.4 nM
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CP0373673
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3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
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C31H32N2O6
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1
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| 1 |
Ki = 7.15 nM
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CP0050692
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(1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-4-methoxy-phenyl)-5-propoxy-indan-2-carboxylic acid
Show/Hide
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C29H28O9
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1
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| 1 |
Ki = 14.7 nM
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CP0380455
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3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
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C31H32N2O7
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1
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| 1 |
Ki = 14.7 nM
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CP0460299
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(1R,2S,3R)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-4-methoxy-phenyl)-5-propoxy-indan-2-carboxylic acid
Show/Hide
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C29H28O9
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1
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| 1 |
Ki = 14.7 nM
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CP0506531
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2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-hydroxy-phenyl)-ethoxy]-3,3-diphenyl-propionic acid
Show/Hide
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C29H28N2O5
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1
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| 1 |
Ki = 16.2 nM
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CP0374765
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3-Methoxy-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
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C22H22N2O5
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1
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| 1 |
Ki = 19.7 nM
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CP0408416
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2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-[(E)-3-(3,4,5-trimethoxy-phenyl)-allyloxy]-propionic acid
Show/Hide
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C33H34N2O7
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1
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| 1 |
Ki = 20 nM
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CP0395101
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3-Methoxy-2-(4-methoxy-6,7-dihydro-5H-cyclopentapyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
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C24H24N2O5
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1
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| 1 |
Ki = 20.4 nM
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CP0448640
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2-(4-Methoxy-6-methyl-pyrimidin-2-yloxy)-3-[2-(4-methoxy-phenyl)-ethoxy]-3,3-diphenyl-propionic acid
Show/Hide
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C30H30N2O6
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1
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| 1 |
Ki = 23.2 nM
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CP0536129
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3-[2-(4-Carboxymethoxy-3-methoxy-phenyl)-ethoxy]-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
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C32H32N2O8
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1
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| 1 |
Ki = 24 nM
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CP0488120
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2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-methoxy-phenyl)-ethoxy]-3,3-diphenyl-propionic acid
Show/Hide
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C30H30N2O5
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1
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| 1 |
Ki = 24.2 nM
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CP0449158
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3-Methoxy-2-(4-methoxy-5,6-dihydro-furo[2,3-d]pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
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C23H22N2O6
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1
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| 1 |
Ki = 24.5 nM
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CP0508726
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2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-ethoxy-3-methoxy-phenyl)-ethoxy]-3,3-diphenyl-propionic acid
Show/Hide
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C32H34N2O6
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1
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| 1 |
Ki = 25.1 nM
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CP0453837
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3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-3,3-bis-(4-ethyl-phenyl)-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)-propionic acid
Show/Hide
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C35H40N2O7
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1
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| 1 |
Ki = 40 nM
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CP0379136
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2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-(2-p-tolyl-ethoxy)-propionic acid
Show/Hide
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C30H30N2O4
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1
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| 1 |
Ki = 55 nM
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CP0435987
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3-(3,4-Dimethoxy-phenoxy)-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
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C29H28N2O6
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1
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| 1 |
Ki = 60 nM
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CP0392713
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3-(3,4-Dimethoxy-benzyloxy)-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
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C30H30N2O6
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1
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| 1 |
Ki = 63 nM
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CP0454351
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2-(4-Methoxy-5,7-dihydro-furo[3,4-d]pyrimidin-2-yloxy)-3-[2-(4-methoxy-phenyl)-ethoxy]-3,3-di-p-tolyl-propionic acid
Show/Hide
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C33H34N2O7
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1
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| 1 |
Ki = 71.2 nM
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CP0424580
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N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N-methyl-2-phenylacetamide
Show/Hide
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C30H28N4O5S
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1
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| 1 |
Ki = 87 nM
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CP0441850
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3-[2-(4-Chloro-phenyl)-ethoxy]-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid
Show/Hide
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C29H27ClN2O4
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1
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| 1 |
Ki = 94.1 nM
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CP0186021
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(1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-[2-(2-hydroxy-ethoxy)-4-methoxy-phenyl]-5-propoxy-indan-2-carboxylic acid
Show/Hide
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C29H30O8
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1
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| 1 |
Ki = 111 nM
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CP0457321
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4-{2-[2-Carboxy-2-(4,6-dimethyl-pyrimidin-2-yloxy)-1,1-diphenyl-ethoxy]-ethyl}-benzoic acid
Show/Hide
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C30H28N2O6
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1
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| 1 |
Ki = 115 nM
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CP0403590
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3,3-Bis-(4-chloro-phenyl)-3-[2-(3,4-dimethoxy-phenyl)-ethoxy]-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)-propionic acid
Show/Hide
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C31H30Cl2N2O7
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1
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| 1 |
Ki = 130 nM
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CP0278704
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3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-(3,4,5-trimethoxybenzyl)furan-2(5H)-one
Show/Hide
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C28H26O9
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1
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| 1 |
Ki = 139 nM
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CP0853532
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Sodium salt (Z)-2-benzo[1,3]dioxol-5-yl-4-(4-methoxy-phenyl)-4-oxo-3-(3,4,5-trimethoxy-benzyl)-but-2-enoate
Show/Hide
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C28H25NaO9
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1
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| 1 |
Ki = 139 nM
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CP0430787
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2'-[(Methyl-phenyl-amino)-methyl]-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
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C28H26N4O4S
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1
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| 1 |
Ki = 150 nM
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CP0497687
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3,3-Bis-(4-ethyl-phenyl)-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)-3-[2-(4-methoxy-phenyl)-ethoxy]-propionic acid
Show/Hide
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C34H38N2O6
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1
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| 1 |
Ki = 160 nM
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CP0442642
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2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-(3-p-tolyl-propoxy)-propionic acid
Show/Hide
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C31H32N2O4
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1
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| 1 |
Ki = 170 nM
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CP0374717
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5-Methyl-pyridine-2-sulfonic acid {6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-[2-(2H-tetrazol-5-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide
Show/Hide
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C25H23N9O6S
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1
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| 1 |
Ki = 175 nM
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CP0393642
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2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-bis-(4-ethyl-phenyl)-3-[2-(4-methoxy-phenyl)-ethoxy]-propionic acid
Show/Hide
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C34H38N2O5
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1
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| 1 |
Ki = 195 nM
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CP0409668
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3,3-Bis-(4-chloro-phenyl)-3-[2-(3,4-dimethoxy-phenyl)-ethoxy]-2-(4-methoxy-6,7-dihydro-5H-cyclopentapyrimidin-2-yloxy)-propionic acid
Show/Hide
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C33H32Cl2N2O7
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1
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| 1 |
Ki = 215 nM
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CP0501241
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2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-phenethyloxy-3,3-diphenyl-propionic acid
Show/Hide
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C29H28N2O4
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1
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| 1 |
Ki = 230 nM
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CP0498054
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2'-(3,3-Dimethyl-2-oxo-pyrrolidin-1-ylmethyl)-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
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C27H28N4O5S
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1
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| 1 |
Ki = 270 nM
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CP0460062
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1-Methyl-1H-indole-2-carboxylic acid [2'-(3,4-dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-methyl-amide
Show/Hide
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C32H29N5O5S
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1
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| 1 |
Ki = 310 nM
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CP0404577
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2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-((E)-3-p-tolyl-allyloxy)-propionic acid
Show/Hide
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C31H30N2O4
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1
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| 1 |
Ki = 320 nM
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CP0414928
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3,5-Dichloro-N-[2'-(3,4-dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-N-methyl-benzamide
Show/Hide
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C29H24Cl2N4O5S
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1
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| 1 |
Ki = 320 nM
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CP0436707
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4-tert-Butyl-N-[6-(3-hydroxy-propyl)-5-(2-methoxy-benzyl)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide
Show/Hide
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C29H33N5O4S
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1
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| 1 |
Ki = 343 nM
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CP0464427
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2'-(3,3-Dimethyl-2-oxo-piperidin-1-ylmethyl)-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
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C28H30N4O5S
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1
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| 1 |
Ki = 360 nM
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CP0449236
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2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid
Show/Hide
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C22H22N2O6
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1
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| 1 |
Ki = 371 nM
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CP0402302
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N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-3,3,3-trifluoro-N-methylpropanamide
Show/Hide
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C25H23F3N4O5S
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1
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| 1 |
Ki = 380 nM
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CP0429972
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N-cyclopropyl-N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-2-methylpropanamide
Show/Hide
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C28H30N4O5S
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1
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| 1 |
Ki = 550 nM
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CP0457278
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N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N-methylbenzamide
Show/Hide
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C29H26N4O5S
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1
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| 1 |
Ki = 580 nM
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CP0379371
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N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N,2,2-trimethylpropanamide
Show/Hide
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C27H30N4O5S
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1
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| 1 |
Ki = 640 nM
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CP0860692
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2'-(3,3-Dimethyl-2-oxo-pyrrolidin-1-yl)-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (4,5-dimethyl-isoxazol-3-yl)-amide
Show/Hide
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C27H28N4O5S
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1
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| 1 |
Ki = 770 nM
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CP0453565
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N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N,2-dimethylpropanamide
Show/Hide
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C26H28N4O5S
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1
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| 1 |
Ki = 790 nM
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CP0536012
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N-[2-[2-[(4,5-dimethyl-1,2-oxazol-3-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]-N,3,3-trimethylbutanamide
Show/Hide
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C27H30N4O5S
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1
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| 1 |
Ki = 810 nM
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CP0464026
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2'-(4,4-Dimethyl-2-oxo-pyrrolidin-1-ylmethyl)-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
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C27H28N4O5S
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1
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| 1 |
Ki = 950 nM
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CP0414951
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4'-Oxazol-2-yl-2'-(pyrimidin-4-ylaminomethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
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C25H22N6O4S
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1
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| 1 |
Ki = 980 nM
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CP0480585
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2'-[(5-Methyl-isoxazol-3-ylamino)-methyl]-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Show/Hide
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C25H23N5O5S
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1
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| 1 |
Ki = 1050 nM
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CP0379025
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N-tert-butyl-2-[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]acetamide
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C26H28N4O5S
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1
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| 1 |
Ki = 1100 nM
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CP0456814
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N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N-methyl-3-phenylpropanamide
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C31H30N4O5S
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1
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| 1 |
Ki = 1200 nM
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CP0517881
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2'-(3-Methyl-2-oxo-imidazolidin-1-ylmethyl)-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C25H25N5O5S
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1
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| 1 |
Ki = 1300 nM
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CP0502578
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N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N-methyl-2-[4-(trifluoromethyl)phenyl]acetamide
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C31H27F3N4O5S
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1
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| 1 |
Ki = 1400 nM
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CP0505432
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4'-Oxazol-2-yl-2'-pyrazol-1-ylmethyl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C24H21N5O4S
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1
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| 1 |
Ki = 1400 nM
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CP0465099
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4'-Oxazol-2-yl-2'-(3-trifluoromethyl-pyrazol-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C25H20F3N5O4S
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1
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| 1 |
Ki = 1500 nM
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CP0393342
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N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N-propan-2-ylacetamide
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C26H28N4O5S
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1
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| 1 |
Ki = 1700 nM
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CP0537094
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4'-Oxazol-2-yl-2'-oxazol-2-ylmethyl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C24H20N4O5S
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1
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| 1 |
Ki = 1700 nM
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CP0480586
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4'-Oxazol-2-yl-2'-styryl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C28H23N3O4S
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1
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| 1 |
Ki = 1900 nM
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CP0536905
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2'-{[Methyl-(2,2,2-trifluoro-ethyl)-amino]-methyl}-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C24H23F3N4O4S
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1
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| 1 |
Ki = 1900 nM
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CP0422899
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N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-2,2-dimethyl-N-propan-2-ylpropanamide
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C29H34N4O5S
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1
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| 1 |
Ki = 2300 nM
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CP0375007
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N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N-methyl-2-pyridin-2-ylacetamide
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C29H27N5O5S
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1
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| 1 |
Ki = 2500 nM
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CP0404230
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4'-Oxazol-2-yl-2'-[(2,2,2-trifluoro-ethylamino)-methyl]-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C23H21F3N4O4S
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1
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| 1 |
Ki = 2700 nM
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CP0375033
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2-Cyclohexyl-N-[2'-(3,4-dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-N-methyl-acetamide
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C30H34N4O5S
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1
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| 1 |
Ki = 2800 nM
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CP0448422
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2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-(4-isopropyl-phenoxy)-3-phenyl-butyric acid methyl ester
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C26H30N2O6
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1
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| 1 |
Ki = 3000 nM
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CP0409673
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N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N,3,3-trimethylbutanamide
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C28H32N4O5S
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1
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| 1 |
Ki = 3360 nM
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CP0414921
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N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]-N-methylacetamide
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C24H24N4O5S
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1
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| 1 |
Ki = 4000 nM
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CP0453326
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2'-Imidazol-1-ylmethyl-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C24H21N5O4S
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1
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| 1 |
Ki = 4300 nM
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CP0498209
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N-[[2-[2-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]methyl]acetamide
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C23H22N4O5S
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1
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| 1 |
Ki = 4400 nM
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CP0430810
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4'-Oxazol-2-yl-2'-phenoxymethyl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C27H23N3O5S
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1
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| 1 |
Ki = 4600 nM
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CP0488937
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2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-(4-methylsulfanyl-phenoxy)-3-phenyl-butyric acid methyl ester
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C24H26N2O6S
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1
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| 1 |
Ki = 4700 nM
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CP0457301
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2'-Isobutoxymethyl-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C25H27N3O5S
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1
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| 1 |
Ki = 4800 nM
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CP0509406
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4'-Pyridin-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C22H19N3O3S
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1
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| 1 |
Ki = 6300 nM
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CP0403956
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2-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-yl]-N,N-dimethyl-acetamide
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C24H24N4O5S
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1
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| 1 |
Ki = 7300 nM
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CP0529647
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4'-Oxazol-2-yl-2'-styryl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C28H23N3O4S
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1
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| 1 |
Ki = 9100 nM
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CP0414947
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4'-Pyrazol-1-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C20H18N4O3S
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1
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| 1 |
Ki = 9400 nM
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CP0498064
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2'-Isopropoxymethyl-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C24H25N3O5S
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1
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| 1 |
Ki = 11000 nM
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CP0527692
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4'-Pyrimidin-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C21H18N4O3S
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1
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| 1 |
Ki = 16000 nM
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CP0088035
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4''-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C20H17N3O4S
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1
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| 1 |
Ki = 18700 nM
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CP0449658
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4'-Pyridin-3-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C22H19N3O3S
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1
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| 1 |
Ki = 20000 nM
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CP0510374
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N-(3,4-dimethyl-1,2-oxazol-5-yl)-2-(4-phenylphenyl)benzenesulfonamide
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C23H20N2O3S
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1
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| 1 |
Ki = 20000 nM
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CP0498220
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4'-Pyrazin-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C21H18N4O3S
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1
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| 1 |
Ki = 22000 nM
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CP0442920
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4'-(1-Oxy-pyridin-2-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C22H19N3O4S
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1
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| 1 |
Ki = 30800 nM
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CP0537792
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4'-Isoxazol-5-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C20H17N3O4S
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1
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| 1 |
Ki = 39000 nM
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CP0430401
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4'-(4,6-Dimethoxy-pyrimidin-2-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C23H22N4O5S
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1
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| 1 |
Ki = 48000 nM
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CP0041337
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5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-2,3-dihydro-oxazol-5-yl)-amide
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C17H19N3O3S
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1
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| 1 |
Ki > 50000 nM
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CP0442023
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2'-[(Isobutyl-methyl-amino)-methyl]-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C26H30N4O4S
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1
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| 1 |
Ki > 50000 nM
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CP0419227
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4'-Thiazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C20H17N3O3S2
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1
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| 1 |
Ki = 52000 nM
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CP0515048
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4'-[1,3,4]Oxadiazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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C19H16N4O4S
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1
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| 1 |
Ki = 75000 nM
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CP0461027
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3-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-2-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide
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C18H15ClN2O6S2
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1
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| 1 |
Ki > 4300 nM
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