General Information of the Compound
| Compound ID |
CP0436737
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| Compound Name |
5-Methyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yl]-amide
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| Structure |
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| Formula |
C26H23N5O6S
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| Molecular Weight |
533.566
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| Canonical SMILES |
COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC#CCO)-c1ccncc1
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| InChI |
InChI=1S/C26H23N5O6S/c1-18-9-10-22(28-17-18)38(33,34)31-25-23(37-21-8-4-3-7-20(21)35-2)26(36-16-6-5-15-32)30-24(29-25)19-11-13-27-14-12-19/h3-4,7-14,17,32H,15-16H2,1-2H3,(H,29,30,31)
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| InChIKey |
PYTGPPKMIDNVTB-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01783, Endothelin receptor type B
Protein ID: PT01372, Endothelin-1 receptor