Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-[2-(toluene-4-sulfonylamino)-ethoxy]-2-(3,4,5-trimethoxy-phenyl)-pyrimidin-4-yl]-amide
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 PubChem ID
CID: 9897092
SID: 14864830
Canonical SMILES
COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCCNS(=O)(=O)c1ccc(C)cc1)-c1cc(OC)c(OC)c(OC)c1
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Compound Formula C37H41N5O10S2
Compound Structure
Protein Name
 Protein Info 
Endothelin receptor type B
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P24530
Gene Name
EDNRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS