Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[4-[[2-(1,3-benzodioxol-5-yl)-2-(6-carbamoyl-1-methylindol-3-yl)acetyl]sulfamoyl]phenyl]acetic acid
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 PubChem ID
CID: 22467237
Canonical SMILES
Cn1cc(C(C(=O)NS(=O)(=O)c2ccc(CC(O)=O)cc2)c2ccc3OCOc3c2)c2ccc(cc12)C(N)=O
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Compound Formula C27H23N3O8S
Compound Structure
Protein Name
 Protein Info 
Endothelin receptor type B
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P24530
Gene Name
EDNRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 574 nM
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   LI
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   TS