Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-prop-2-ynyloxy-pyrimidin-4-yl]-amide
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 PubChem ID
CID: 44385576
Canonical SMILES
COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#C)N1CCOCC1
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Compound Formula C26H29N5O6S
Compound Structure
Protein Name
 Protein Info 
Endothelin receptor type B
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P24530
Gene Name
EDNRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 746 nM
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