Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-pyridin-4-yl-pyrimidin-4-yl]-benzenesulfonamide
    Show/Hide
 PubChem ID
CID: 44384852
Canonical SMILES
COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCC#C)-c1ccncc1
    Show/Hide
Compound Formula C29H28N4O5S
Compound Structure
Protein Name
 Protein Info 
Endothelin receptor type B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Endothelin receptor
Uniprot ID
P24530
Gene Name
EDNRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 295 nM
   TI
   LI
   LO
   TS