Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-((Z)-2,2-dimethyl-pent-3-enyl)-4-(7-methoxy-benzo[1,3]dioxol-5-yl)-pyrrolidine-3-carboxylic acid
    Show/Hide
 PubChem ID
CID: 44339655
Canonical SMILES
CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1CC(C)(C)\C=C/C)C(O)=O)c1cc2OCOc2c(OC)c1
    Show/Hide
Compound Formula C30H46N2O6
Compound Structure
Protein Name
 Protein Info 
Endothelin receptor type B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Endothelin receptor
Uniprot ID
P24530
Gene Name
EDNRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 39700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 45300 nM