Brief Information of the Compound and Protein
Compound Name
4'-Oxazol-2-yl-2'-[(2,2,2-trifluoro-ethylamino)-methyl]-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
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PubChem ID
CID: 10973218
SID: 16029506
Canonical SMILES
Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2CNCC(F)(F)F)-c2ncco2)c1C
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Compound Formula C23H21F3N4O4S
Compound Structure
Protein Name
Endothelin receptor type B
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P24530
Gene Name
EDNRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 2700 nM
   TI
   LI
   LO
   TS