Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-1-methyl-6-phenyl-5,6-dihydro-4H-2,3,5,10b-tetraaza-benzo[e]azulen-6-yl)-acetic acid
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 PubChem ID
CID: 10226239
SID: 15227216
Canonical SMILES
Cc1nnc2CN[C@@]([C@H](Oc3nc(C)cc(C)n3)C(O)=O)(c3ccccc3)c3ccccc3-n12
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Compound Formula C25H24N6O3
Compound Structure
Protein Name
 Protein Info 
Endothelin receptor type B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P24530
Gene Name
EDNRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS