Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-6-[(S)-Carboxy-(4,6-dimethyl-pyrimidin-2-yloxy)-methyl]-1-methyl-6-phenyl-5,6-dihydro-4H-2,5,10b-triaza-benzo[e]azulene-3-carboxylic acid
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 PubChem ID
CID: 11202819
SID: 16284656
Canonical SMILES
Cc1nc(C(O)=O)c2CN[C@@]([C@H](Oc3nc(C)cc(C)n3)C(O)=O)(c3ccccc3)c3ccccc3-n12
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Compound Formula C27H25N5O5
Compound Structure
Protein Name
 Protein Info 
Endothelin receptor type B
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P24530
Gene Name
EDNRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 711 nM
   TI
   LI
   LO
   TS