Brief Information of the Compound and Protein
Compound Name
N-[5-(2-methoxyphenoxy)-2-pyrimidin-2-yl-6-[2-[5-(trifluoromethyl)pyrimidin-2-yl]oxyethoxy]pyrimidin-4-yl]-2-phenylethanesulfonamide
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PubChem ID
CID: 71455062
SID: 163485267
Canonical SMILES
COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(nc1OCCOc1ncc(cn1)C(F)(F)F)-c1ncccn1
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Compound Formula C30H26F3N7O6S
Compound Structure
Protein Name
Endothelin receptor type B
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P24530
Gene Name
EDNRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 145 nM
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