Brief Information of the Compound and Protein
Compound Name
2'-(3,3-Dimethyl-2-oxo-pyrrolidin-1-yl)-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (4,5-dimethyl-isoxazol-3-yl)-amide
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PubChem ID
CID: 9958321
SID: 14934045
Canonical SMILES
Cc1onc(NS(=O)(=O)c2ccccc2-c2ccc(-c3ncco3)cc2CN2CCC(C)(C)C2=O)c1C
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Compound Formula C27H28N4O5S
Compound Structure
Protein Name
Endothelin receptor type B
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P24530
Gene Name
EDNRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 770 nM
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   LI
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