Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-2-(1,3-benzodioxol-5-yl)-2-[6-(hydroxymethyl)-1-methylindol-3-yl]-N-(2-methoxy-4-methylphenyl)sulfonylacetamide
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 PubChem ID
CID: 76312118
Canonical SMILES
COc1cc(C)ccc1S(=O)(=O)NC(=O)[C@H](c1cn(C)c2cc(CO)ccc12)c1ccc2OCOc2c1
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Compound Formula C27H26N2O7S
Compound Structure
Protein Name
 Protein Info 
Endothelin receptor type B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P24530
Gene Name
EDNRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 683 nM
   TI
   LI
   LO
   TS
2
Ki = 1503 nM
   TI
   LI
   LO
   TS