Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-{(S)-5-[(S)-Carboxy-(4,6-dimethyl-pyrimidin-2-yloxy)-methyl]-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[e][1,4]diazepin-1-ylmethyl}-benzoic acid methyl ester
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 PubChem ID
CID: 10303311
SID: 15310024
Canonical SMILES
COC(=O)c1ccc(CN2c3ccccc3[C@](NCC2=O)([C@H](Oc2nc(C)cc(C)n2)C(O)=O)c2ccccc2)cc1
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Compound Formula C32H30N4O6
Compound Structure
Protein Name
 Protein Info 
Endothelin receptor type B
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P24530
Gene Name
EDNRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 70.3 nM
   TI
   LI
   LO
   TS