| Compound ID |
Compound Name |
Compound Formula |
|
CP0503562
|
4-(cyclohexylmethyl)-1-[3-(1H-imidazol-5-yl)propyl]triazole
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|
C15H23N5
|
2
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
Ki = 8.318 nM
|
|
|
|
CP0036920
|
2-(1H-imidazol-4-yl)ethan-1-amine
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|
C5H9N3
|
5
|
| 1 |
EC50 = 13 nM
|
|
|
| 2 |
EC50 = 25.12 nM
|
|
|
| 3 |
Ki = 9 nM
|
|
|
| 4 |
Ki = 12.02 nM
|
|
|
| 5 |
Ki = 15.85 nM
|
|
|
|
CP0850150
|
4-(1H-Imidazol-4-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-ylamine
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|
C12H17N7
|
1
|
| 1 |
EC50 = 16.22 nM
|
|
|
|
CP0382899
|
1-cyano-2-[[(1S,3S)-3-(1H-imidazol-5-yl)cyclopentyl]methyl]-3-(2-phenylsulfanylethyl)guanidine
Show/Hide
|
C19H24N6S
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0880836
|
4-(2-methoxypyridin-3-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine
Show/Hide
|
C15H20N6O
|
1
|
| 1 |
EC50 = 26.92 nM
|
|
|
|
CP0845898
|
4-(4-Methylpiperazin-1-yl)pyrimidine-2,5-diamine
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|
C9H16N6
|
1
|
| 1 |
EC50 = 33.88 nM
|
|
|
|
CP0823737
|
SID50106398
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|
C5H11Cl2N3
|
1
|
| 1 |
EC50 = 33.88 nM
|
|
|
|
CP0425035
|
4-(4-methylpiperazin-1-yl)pyrimidin-2-amine
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|
C9H15N5
|
2
|
| 1 |
EC50 = 43.65 nM
|
|
|
| 2 |
Ki = 31 nM
|
|
|
|
CP0377316
|
1-cyano-3-[[(1S,3S)-3-(1H-imidazol-5-yl)cyclopentyl]methyl]-2-methylguanidine
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|
C12H18N6
|
1
|
| 1 |
EC50 = 63 nM
|
|
|
|
CP0171842
|
4-N-benzyl-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine
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|
C16H22N6
|
1
|
| 1 |
EC50 = 64.57 nM
|
|
|
|
CP0416437
|
4-[(1E,3E)-4-[1-[5-(1H-imidazol-5-yl)pentyl]-2,6-dimethylpyridin-1-ium-4-yl]buta-1,3-dienyl]-N,N-dimethylaniline;2,2,2-trifluoroacetate;2,2,2-trifluoroacetic acid
Show/Hide
|
C31H36F6N4O4
|
1
|
| 1 |
EC50 = 64.57 nM
|
|
|
|
CP0044460
|
N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide
Show/Hide
|
C15H24N4S
|
7
|
| 1 |
EC50 = 79.43 nM
|
|
|
| 2 |
IC50 = 489.78 nM
|
|
|
| 3 |
IC50 = 667 nM
|
|
|
| 4 |
Ki = 43 nM
|
|
|
| 5 |
Ki = 47.86 nM
|
|
|
| 6 |
Ki = 63.1 nM
|
|
|
| 7 |
Ki = 79 nM
|
|
|
|
CP0469142
|
4-(cyclohexylmethyl)-1-[2-(1H-imidazol-5-yl)ethyl]triazole
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|
C14H21N5
|
2
|
| 1 |
EC50 = 158.49 nM
|
|
|
| 2 |
Ki = 776.25 nM
|
|
|
|
CP0930222
|
4-Benzoimidazol-1-yl-6-(4-methylpiperazin-1-yl)pyrimidin-2-ylamine
Show/Hide
|
C16H19N7
|
1
|
| 1 |
EC50 = 177.83 nM
|
|
|
|
CP0377318
|
1-cyano-2-[[(1R,3R)-3-(1H-imidazol-5-yl)cyclopentyl]methyl]-3-(2-phenylsulfanylethyl)guanidine
Show/Hide
|
C19H24N6S
|
1
|
| 1 |
EC50 = 500 nM
|
|
|
|
CP0858873
|
4-tert-Butyl-2-methoxy-6-(4-methylpiperazin-1-yl)pyrimidine
Show/Hide
|
C14H24N4O
|
1
|
| 1 |
EC50 = 1202.26 nM
|
|
|
|
CP0851246
|
4-[2-Amino-6-(4-methylpiperazin-1-yl)pyridin-4-yl]-benzonitrile
Show/Hide
|
C17H19N5
|
1
|
| 1 |
EC50 = 2344.23 nM
|
|
|
|
CP0851286
|
4-Imidazol-1-yl-6-(4-methylpiperazin-1-yl)pyrimidin-2-ylamine
Show/Hide
|
C12H17N7
|
1
|
| 1 |
EC50 = 2511.89 nM
|
|
|
|
CP0851247
|
1-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-1H-pyridin-2-one
Show/Hide
|
C14H18N6O
|
1
|
| 1 |
EC50 = 3890.45 nM
|
|
|
|
CP0916702
|
4-tert-butyl-2-chloro-6-(4-methylpiperazin-1-yl)pyrimidine
Show/Hide
|
C13H21ClN4
|
1
|
| 1 |
EC50 = 4897.79 nM
|
|
|
|
CP0896307
|
[4-tert-Butyl-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl]dimethylamine
Show/Hide
|
C15H27N5
|
1
|
| 1 |
EC50 = 11481.54 nM
|
|
|
|
CP0388279
|
4-[(1E,3E)-4-[1-[4-(1H-imidazol-5-yl)butyl]-2,6-dimethylpyridin-1-ium-4-yl]buta-1,3-dienyl]-N,N-dimethylaniline;2,2,2-trifluoroacetate;2,2,2-trifluoroacetic acid
Show/Hide
|
C30H34F6N4O4
|
1
|
| 1 |
IC50 = 15.49 nM
|
|
|
|
CP0220828
|
4-N-(cyclopropylmethyl)-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidine-2,4-diamine
Show/Hide
|
C13H22N6
|
5
|
| 1 |
IC50 = 53.7 nM
|
|
|
| 2 |
Kd = 25.12 nM
|
|
|
| 3 |
Ki = 1.56 nM
|
|
|
| 4 |
Ki = 2.4 nM
|
|
|
| 5 |
Ki = 10.23 nM
|
|
|
|
CP0271676
|
7-cyclopropyl-4-[3-(methylamino)azetidin-1-yl]pyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C14H18N6
|
3
|
| 1 |
IC50 = 70.79 nM
|
|
|
| 2 |
Kd = 13.49 nM
|
|
|
| 3 |
Ki = 5.248 nM
|
|
|
|
CP0331875
|
7-cyclopentyl-4-[3-(methylamino)azetidin-1-yl]pyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C16H22N6
|
3
|
| 1 |
IC50 = 97.72 nM
|
|
|
| 2 |
Kd = 10.23 nM
|
|
|
| 3 |
Ki = 6.457 nM
|
|
|
|
CP0221098
|
7-ethyl-4-[3-(methylamino)azetidin-1-yl]pyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C13H18N6
|
3
|
| 1 |
IC50 = 112.2 nM
|
|
|
| 2 |
Kd = 8.511 nM
|
|
|
| 3 |
Ki = 10.72 nM
|
|
|
|
CP0043846
|
7-ethyl-4-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C14H20N6
|
3
|
| 1 |
IC50 = 125.89 nM
|
|
|
| 2 |
Kd = 21.38 nM
|
|
|
| 3 |
Ki = 9.12 nM
|
|
|
|
CP0338441
|
N-(3-aminoquinoxalin-2-yl)-4-(piperidin-1-ylmethyl)benzamide
Show/Hide
|
C21H23N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0761405
|
N-(3-aminoquinoxalin-2-yl)-4-(piperidin-1-ylmethyl)benzamide hydrochloride
Show/Hide
|
C21H24ClN5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0315602
|
3-methoxy-1-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]pyridin-4-one
Show/Hide
|
C19H24N2O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0041262
|
5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-indole
Show/Hide
|
C14H16ClN3O
|
8
|
| 1 |
Kd = 3.981 nM
|
|
|
| 2 |
Ki = 4 nM
|
|
|
| 3 |
Ki = 4.169 nM
|
|
|
| 4 |
Ki = 6.31 nM
|
|
|
| 5 |
Ki = 6.8 nM
|
|
|
| 6 |
Ki = 8 nM
|
|
|
| 7 |
Ki = 12.02 nM
|
|
|
| 8 |
Ki = 15.85 nM
|
|
|
|
CP0081459
|
7-(furan-2-yl)-4-piperazin-1-ylquinazolin-2-amine
Show/Hide
|
C16H17N5O
|
3
|
| 1 |
Kd = 40.74 nM
|
|
|
| 2 |
Ki = 15.14 nM
|
|
|
| 3 |
Ki = 16 nM
|
|
|
|
CP0399211
|
4-N-(2,2-dimethylpropyl)-6-[3-(methylamino)azetidin-1-yl]pyrimidine-2,4-diamine
Show/Hide
|
C13H24N6
|
2
|
| 1 |
Ki = 0.034 nM
|
|
|
| 2 |
Ki = 1.7 nM
|
|
|
|
CP0491739
|
2-arylbenzimidazole derivative, 10
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|
C24H31ClN4O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0041493
|
Clobenpropit
Show/Hide
|
C14H17ClN4S
|
7
|
| 1 |
Ki = 1 nM
|
|
|
| 2 |
Ki = 1.585 nM
|
|
|
| 3 |
Ki = 2.512 nM
|
|
|
| 4 |
Ki = 4.3 nM
|
|
|
| 5 |
Ki = 10 nM
|
|
|
| 6 |
Ki = 15.85 nM
|
|
|
| 7 |
Ki = 50.12 nM
|
|
|
|
CP0387896
|
4-N-(3,3-dimethylbutyl)-6-[3-(methylamino)azetidin-1-yl]pyrimidine-2,4-diamine
Show/Hide
|
C14H26N6
|
2
|
| 1 |
Ki = 1.5 nM
|
|
|
| 2 |
Ki = 4.6 nM
|
|
|
|
CP0093148
|
4-[3-(methylamino)azetidin-1-yl]spiro[6,7-dihydro-5H-quinazoline-8,1'-cyclopentane]-2-amine
Show/Hide
|
C16H25N5
|
1
|
| 1 |
Ki = 1.514 nM
|
|
|
|
CP0098027
|
2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide
Show/Hide
|
C6H10N4S
|
2
|
| 1 |
Ki = 1.6 nM
|
|
|
| 2 |
Ki = 6.31 nM
|
|
|
|
CP0093147
|
4-[(3R)-3-(methylamino)pyrrolidin-1-yl]spiro[6,7-dihydro-5H-quinazoline-8,1'-cyclopentane]-2-amine
Show/Hide
|
C17H27N5
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0744165
|
7-cyclopentyl-4-(3-(methylamino)azetidin-1-yl)quinazolin-2-amine
Show/Hide
|
C17H23N5
|
1
|
| 1 |
Ki = 3.388 nM
|
|
|
|
CP0148014
|
2-[[6-chloro-2-(4-methylpiperazin-1-yl)quinazolin-4-yl]amino]-N-phenylethanesulfonamide
Show/Hide
|
C21H25ClN6O2S
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0218637
|
4-(4-methylpiperazin-1-yl)-7-thiophen-3-ylquinazolin-2-amine
Show/Hide
|
C17H19N5S
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0205085
|
2,4-diamino-5,6-disubstituted pyrimidine, 10
Show/Hide
|
C17H21N5
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0335770
|
7-(furan-2-yl)-4-(4-methylpiperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C17H19N5O
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0259827
|
4-(4-methylpiperazin-1-yl)-6-phenylpyrimidin-2-amine
Show/Hide
|
C15H19N5
|
2
|
| 1 |
Ki = 5.012 nM
|
|
|
| 2 |
Ki = 6.31 nM
|
|
|
|
CP0435841
|
(7-amino-5-chloro-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C14H17ClN4O
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0373129
|
6,7-dichloro-3-(4-methylpiperazin-1-yl)-1H-quinoxalin-2-one
Show/Hide
|
C13H14Cl2N4O
|
2
|
| 1 |
Ki = 5.623 nM
|
|
|
| 2 |
Ki = 6 nM
|
|
|
|
CP0146662
|
7-(furan-3-yl)-4-(4-methylpiperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C17H19N5O
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0180153
|
7-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepine
Show/Hide
|
C18H18ClN3O
|
2
|
| 1 |
Ki = 6 nM
|
|
|
| 2 |
Ki = 28.18 nM
|
|
|
|
CP0480468
|
(7aR,11aR)-4-piperazin-1-yl-5,6,7a,8,9,10,11,11a-octahydro-[1]benzofuro[2,3-h]quinazolin-2-amine
Show/Hide
|
C18H25N5O
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0233670
|
(4,5-Dichloro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H15Cl2N3O
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0428693
|
(5-chloro-4-fluoro-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C14H15ClFN3O
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0521646
|
(5-chloro-7-fluoro-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C14H15ClFN3O
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0530160
|
(5-chloro-7-methyl-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C15H18ClN3O
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0275225
|
4-(1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl)-9-phenyl-6,7,8,9-tetrahydro-5H-cyclohepta[d]pyrimidin-2-amine
Show/Hide
|
C22H29N5
|
1
|
| 1 |
Ki = 7.079 nM
|
|
|
|
CP0673021
|
7-cyclopropyl-4-(3-(methylamino)azetidin-1-yl)quinazolin-2-amine
Show/Hide
|
C15H19N5
|
1
|
| 1 |
Ki = 7.079 nM
|
|
|
|
CP0270914
|
6-chloro-2-(4-methylpiperazin-1-yl)-N-(thiophen-2-ylmethyl)quinazolin-4-amine
Show/Hide
|
C18H20ClN5S
|
1
|
| 1 |
Ki = 7.586 nM
|
|
|
|
CP0500526
|
4-(cyclopentylmethyl)-1-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
|
C14H21N5
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0280476
|
[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(6-fluoro-1H-benzimidazol-2-yl)methanimine
Show/Hide
|
C15H18FN5
|
1
|
| 1 |
Ki = 9.1 nM
|
|
|
|
CP0388999
|
[(3aR,6aS)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(5-fluoro-4-methyl-1H-benzimidazol-2-yl)methanimine
Show/Hide
|
C16H20FN5
|
1
|
| 1 |
Ki = 9.3 nM
|
|
|
|
CP0659153
|
7-ethyl-4-(4-methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C14H20N6
|
1
|
| 1 |
Ki = 9.333 nM
|
|
|
|
CP0077286
|
[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(5,6-difluoro-1H-benzimidazol-2-yl)methanimine
Show/Hide
|
C15H17F2N5
|
2
|
| 1 |
Ki = 10 nM
|
|
|
| 2 |
Ki = 17.2 nM
|
|
|
|
CP0487161
|
(5-chloro-1H-indol-2-yl)-(3-pyrrolidin-1-ylazetidin-1-yl)methanone
Show/Hide
|
C16H18ClN3O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0673019
|
(R)-7-cyclopropyl-4-(3-(methylamino)pyrrolidin-1-yl)pyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C15H20N6
|
1
|
| 1 |
Ki = 10.23 nM
|
|
|
|
CP0744164
|
7-ethyl-4-(3-(methylamino)azetidin-1-yl)quinazolin-2-amine
Show/Hide
|
C14H19N5
|
1
|
| 1 |
Ki = 11.22 nM
|
|
|
|
CP0899613
|
7-cyclopropyl-4-(piperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C15H19N5
|
1
|
| 1 |
Ki = 11.48 nM
|
|
|
|
CP0659150
|
(R)-7-isopropyl-4-(3-(methylamino)pyrrolidin-1-yl)pyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C15H22N6
|
1
|
| 1 |
Ki = 12.3 nM
|
|
|
|
CP0744166
|
7-cyclopentyl-4-(piperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C17H23N5
|
1
|
| 1 |
Ki = 12.3 nM
|
|
|
|
CP0100102
|
[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(1H-benzimidazol-2-yl)methanimine
Show/Hide
|
C15H19N5
|
1
|
| 1 |
Ki = 12.4 nM
|
|
|
|
CP0214392
|
5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole
Show/Hide
|
C13H15IN2O
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0400807
|
3-(1H-imidazol-5-yl)propyl N'-[(4-chlorophenyl)methyl]-N-cyclohexylcarbamimidothioate
Show/Hide
|
C20H27ClN4S
|
5
|
| 1 |
Ki = 12.59 nM
|
|
|
| 2 |
Ki = 47.86 nM
|
|
|
| 3 |
Ki = 63.1 nM
|
|
|
| 4 |
Ki = 158.49 nM
|
|
|
| 5 |
Ki = 316.23 nM
|
|
|
|
CP0114132
|
(7-Methyl-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C15H19N3O
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0173069
|
5-chloro-2-(piperazin-1-ylcarbonyl)-1H-indole
Show/Hide
|
C13H14ClN3O
|
2
|
| 1 |
Ki = 12.59 nM
|
|
|
| 2 |
Ki = 25.7 nM
|
|
|
|
CP0435390
|
(5-chloro-7-methyl-1H-indol-2-yl)-piperazin-1-ylmethanone
Show/Hide
|
C14H16ClN3O
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0318899
|
2,4-diamino-5,6-disubstituted pyrimidine, 8
Show/Hide
|
C15H17N5
|
1
|
| 1 |
Ki = 12.88 nM
|
|
|
|
CP0391665
|
4-N-[(3-fluorophenyl)methyl]-6-[3-(methylamino)azetidin-1-yl]pyrimidine-2,4-diamine
Show/Hide
|
C15H19FN6
|
2
|
| 1 |
Ki = 13 nM
|
|
|
| 2 |
Ki = 18 nM
|
|
|
|
CP0917026
|
7-ethyl-4-(piperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C14H19N5
|
1
|
| 1 |
Ki = 14.79 nM
|
|
|
|
CP0392039
|
1-[3-[2-amino-4-(4-methylpiperazin-1-yl)quinazolin-7-yl]phenyl]ethanone
Show/Hide
|
C21H23N5O
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0768043
|
7-tert-butyl-4-(3-(methylamino)azetidin-1-yl)quinazolin-2-amine
Show/Hide
|
C16H23N5
|
1
|
| 1 |
Ki = 15.14 nM
|
|
|
|
CP0247209
|
2,4-diamino-5,6-disubstituted pyrimidine, 6
Show/Hide
|
C17H21N5
|
1
|
| 1 |
Ki = 15.49 nM
|
|
|
|
CP0071086
|
(5-Fluoro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H16FN3O
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0160979
|
(7-Amino-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H18N4O
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0446961
|
(5-chloro-7-fluoro-1H-indol-2-yl)-(3-pyrrolidin-1-ylazetidin-1-yl)methanone
Show/Hide
|
C16H17ClFN3O
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0072183
|
[(3aR,6aS)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(5-chloro-1H-indol-2-yl)methanone
Show/Hide
|
C16H18ClN3O
|
2
|
| 1 |
Ki = 16 nM
|
|
|
| 2 |
Ki = 27 nM
|
|
|
|
CP0868684
|
3-(1H-Imidazol-4-yl)propyl N-Butyl-N'-cyclopentylcarbamimidothioate dihydrobromide
Show/Hide
|
C16H29BrN4S
|
1
|
| 1 |
Ki = 16.22 nM
|
|
|
|
CP0673020
|
(R)-7-ethyl-4-(3-(methylamino)pyrrolidin-1-yl)quinazolin-2-amine
Show/Hide
|
C15H21N5
|
1
|
| 1 |
Ki = 16.98 nM
|
|
|
|
CP0533462
|
7-bromo-4-(4-methylpiperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C13H16BrN5
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0476301
|
4-(4-methylpiperazin-1-yl)-7-phenylquinazolin-2-amine
Show/Hide
|
C19H21N5
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0110239
|
4-(1H-imidazol-4-ylmethyl)piperidine
Show/Hide
|
C9H15N3
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0114129
|
(7-Chloro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H16ClN3O
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0521644
|
(7-fluoro-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C14H16FN3O
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0537110
|
(5-chloro-7-fluoro-1H-indol-2-yl)-piperazin-1-ylmethanone
Show/Hide
|
C13H13ClFN3O
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0290795
|
[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(4,5,6-trifluoro-1H-benzimidazol-2-yl)methanimine
Show/Hide
|
C15H16F3N5
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0381034
|
4-(1-cyclohexylethyl)-1-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
|
C16H25N5
|
1
|
| 1 |
Ki = 21.38 nM
|
|
|
|
CP0861813
|
(R)-7-cyclopropyl-4-(3-(methylamino)pyrrolidin-1-yl)quinazolin-2-amine
Show/Hide
|
C16H21N5
|
1
|
| 1 |
Ki = 21.88 nM
|
|
|
|
CP0533461
|
7-methyl-4-(4-methylpiperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C14H19N5
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0280475
|
[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(4,5-difluoro-1H-benzimidazol-2-yl)methanimine
Show/Hide
|
C15H17F2N5
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0071085
|
(5-Hydroxy-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H17N3O2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0249606
|
(1H-Indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H17N3O
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0378093
|
(6-hydroxy-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C14H17N3O2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0659152
|
7-isopropyl-4-(3-(methylamino)azetidin-1-yl)pyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C14H20N6
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0066043
|
(5-Chloro-1H-benzoimidazol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C13H15ClN4O
|
2
|
| 1 |
Ki = 26 nM
|
|
|
| 2 |
Ki = 39.6 nM
|
|
|
|
CP0336633
|
6-chloro-N-(furan-3-ylmethyl)-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C18H20ClN5O
|
1
|
| 1 |
Ki = 26.92 nM
|
|
|
|
CP0525043
|
4-[2-amino-4-(4-methylpiperazin-1-yl)quinazolin-7-yl]benzonitrile
Show/Hide
|
C20H20N6
|
1
|
| 1 |
Ki = 29 nM
|
|
|
|
CP0917434
|
3-(1H-imidazol-4-yl)propyl N-tert-butyl-N'-cyclopentylcarbamimidothioate dihydrobromide
Show/Hide
|
C16H29BrN4S
|
1
|
| 1 |
Ki = 29.51 nM
|
|
|
|
CP0962760
|
4-(4-methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-2-amine
Show/Hide
|
C12H16N6
|
1
|
| 1 |
Ki = 30.9 nM
|
|
|
|
CP0202795
|
2-(diaminomethylideneamino)ethyl carbamimidothioate
Show/Hide
|
C4H11N5S
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0895744
|
3-(1H-Imidazol-4-yl)propyl N-Cyclohexyl-N'-cyclopentylcarbamimidothioate dihydrobromide
Show/Hide
|
C18H31BrN4S
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0231594
|
(5-Amino-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H18N4O
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0399417
|
(4-chloro-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C14H16ClN3O
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0416307
|
(5-chloro-7-methyl-1H-indol-2-yl)-(3-pyrrolidin-1-ylazetidin-1-yl)methanone
Show/Hide
|
C17H20ClN3O
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0435836
|
(4-fluoro-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C14H16FN3O
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0446960
|
(5-chloro-4-fluoro-1H-indol-2-yl)-(4-methyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C15H17ClFN3O
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0418768
|
4-(4-methylpiperazin-1-yl)-8-phenylquinazolin-2-amine
Show/Hide
|
C19H21N5
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0461779
|
4-(4-methylpiperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C13H17N5
|
2
|
| 1 |
Ki = 32 nM
|
|
|
| 2 |
Ki = 44.67 nM
|
|
|
|
CP0401913
|
6-chloro-2-(4-methylpiperazin-1-yl)-N-[(3-methylthiophen-2-yl)methyl]quinazolin-4-amine
Show/Hide
|
C19H22ClN5S
|
1
|
| 1 |
Ki = 33.88 nM
|
|
|
|
CP0068173
|
2-Aminopyrimidine analog., 4
Show/Hide
|
C16H18N6
|
1
|
| 1 |
Ki = 34.67 nM
|
|
|
|
CP0389744
|
6-chloro-2-(4-methylpiperazin-1-yl)-N-(thiophen-3-ylmethyl)quinazolin-4-amine
Show/Hide
|
C18H20ClN5S
|
1
|
| 1 |
Ki = 35.48 nM
|
|
|
|
CP0659372
|
7-tert-butyl-4-(piperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C16H23N5
|
1
|
| 1 |
Ki = 35.48 nM
|
|
|
|
CP0429212
|
6-chloro-2-(4-methylpiperazin-1-yl)-N-[(4-methylthiophen-2-yl)methyl]quinazolin-4-amine
Show/Hide
|
C19H22ClN5S
|
1
|
| 1 |
Ki = 38.9 nM
|
|
|
|
CP0292148
|
[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(6-fluoro-1H-benzimidazol-2-yl)methanone
Show/Hide
|
C15H17FN4O
|
3
|
| 1 |
Ki = 39 nM
|
|
|
| 2 |
Ki = 83 nM
|
|
|
| 3 |
Ki = 145 nM
|
|
|
|
CP0432083
|
2-benzyl-3-(4-methylpiperazin-1-yl)quinoxaline
Show/Hide
|
C20H22N4
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0229853
|
2,4-diamino-5,6-disubstituted pyrimidine, 14
Show/Hide
|
C19H25N5
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0433387
|
(7-fluoro-1H-indol-2-yl)-(3-pyrrolidin-1-ylazetidin-1-yl)methanone
Show/Hide
|
C16H18FN3O
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0521663
|
(7-methyl-1H-indol-2-yl)-piperazin-1-ylmethanone
Show/Hide
|
C14H17N3O
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0521664
|
(5-chloro-1H-indol-2-yl)-(4-methyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C15H18ClN3O
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0566482
|
(4-fluoro-7-methyl-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C15H18FN3O
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0286034
|
2-Aminopyrimidine analog., 25
Show/Hide
|
C15H16N6
|
1
|
| 1 |
Ki = 41.69 nM
|
|
|
|
CP0891660
|
3-(1H-Imidazol-4-yl)propyl N-Benzyl-N'-cyclopentylcarbamimidothioate dihydrobromide
Show/Hide
|
C19H27BrN4S
|
1
|
| 1 |
Ki = 42.66 nM
|
|
|
|
CP0095456
|
4-[(3R)-3-(methylamino)pyrrolidin-1-yl]-8-phenyl-6,7,8,9-tetrahydro-5H-cyclohepta[d]pyrimidin-2-amine
Show/Hide
|
C20H27N5
|
1
|
| 1 |
Ki = 48.98 nM
|
|
|
|
CP0071089
|
(5-methyl-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C15H19N3O
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0247208
|
2,4-diamino-5,6-disubstituted pyrimidine, 7
Show/Hide
|
C16H19N5
|
1
|
| 1 |
Ki = 52.48 nM
|
|
|
|
CP0074916
|
[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(5,6-difluoro-1H-benzimidazol-2-yl)methanone
Show/Hide
|
C15H16F2N4O
|
3
|
| 1 |
Ki = 53 nM
|
|
|
| 2 |
Ki = 128 nM
|
|
|
| 3 |
Ki = 236 nM
|
|
|
|
CP0674429
|
2-amino-4-(3-(methylamino)azetidin-1-yl)pyrido[3,2-d]pyrimidine-7-carbonitrile
Show/Hide
|
C12H13N7
|
1
|
| 1 |
Ki = 53.7 nM
|
|
|
|
CP0502583
|
4-(cycloheptylmethyl)-1-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
|
C16H25N5
|
1
|
| 1 |
Ki = 54.95 nM
|
|
|
|
CP0496246
|
7-(4-methoxyphenyl)-4-(4-methylpiperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C20H23N5O
|
1
|
| 1 |
Ki = 55 nM
|
|
|
|
CP0077287
|
[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(6-chloro-1H-benzimidazol-2-yl)methanimine
Show/Hide
|
C15H18ClN5
|
1
|
| 1 |
Ki = 56 nM
|
|
|
|
CP0401910
|
6-chloro-2-(4-methylpiperazin-1-yl)-N-(2-thiophen-2-ylethyl)quinazolin-4-amine
Show/Hide
|
C19H22ClN5S
|
1
|
| 1 |
Ki = 60.26 nM
|
|
|
|
CP0450853
|
3-(4-methylpiperazin-1-yl)-1H-quinoxalin-2-one
Show/Hide
|
C13H16N4O
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0475814
|
(5-chloro-7-fluoro-1H-indol-2-yl)-(4-methyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C15H17ClFN3O
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0489247
|
(5-chloro-1H-indol-2-yl)-(1,4-diazepan-1-yl)methanone
Show/Hide
|
C14H16ClN3O
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0500525
|
1-[3-(1H-imidazol-5-yl)propyl]-4-pentyltriazole
Show/Hide
|
C13H21N5
|
1
|
| 1 |
Ki = 67.61 nM
|
|
|
|
CP0430973
|
6-chloro-N-methyl-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C14H18ClN5
|
1
|
| 1 |
Ki = 70.79 nM
|
|
|
|
CP0894043
|
3-(1H-Imidazol-4-yl)propyl N-Benzyl-N'-cyclohexylcarbamimidothioate dihydrobromide
Show/Hide
|
C20H29BrN4S
|
1
|
| 1 |
Ki = 75.86 nM
|
|
|
|
CP0511797
|
1-(cyclohexylmethyl)-4-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
|
C15H23N5
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0399400
|
(4,7-difluoro-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C14H15F2N3O
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0399418
|
(6-amino-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C14H18N4O
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0450327
|
(4-methylpiperazin-1-yl)-(5-nitro-1H-indol-2-yl)methanone
Show/Hide
|
C14H16N4O3
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0566480
|
(7-methyl-1H-indol-2-yl)-(3-pyrrolidin-1-ylazetidin-1-yl)methanone
Show/Hide
|
C17H21N3O
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0399210
|
N-(3,3-dimethylbutyl)-6-(4-methylpiperazin-1-yl)pyrimidin-4-amine
Show/Hide
|
C15H27N5
|
2
|
| 1 |
Ki = 82 nM
|
|
|
| 2 |
Ki = 92 nM
|
|
|
|
CP0401985
|
6-chloro-N-(furan-2-ylmethyl)-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C18H20ClN5O
|
1
|
| 1 |
Ki = 89.13 nM
|
|
|
|
CP0441304
|
4-cyclohexyl-1-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
|
C14H21N5
|
1
|
| 1 |
Ki = 89.13 nM
|
|
|
|
CP0875997
|
3-(1H-imidazol-4-yl)propyl N-butyl-N'-(3,4-dichlorobenzyl)carbamimidothioate dihydrobromide
Show/Hide
|
C18H25BrCl2N4S
|
1
|
| 1 |
Ki = 89.13 nM
|
|
|
|
CP0894044
|
3-(1H-imidazol-4-yl)propyl N-butyl-N'-(4-chlorobenzyl)carbamimidothioate dihydrobromide
Show/Hide
|
C18H26BrClN4S
|
1
|
| 1 |
Ki = 89.13 nM
|
|
|
|
CP0428606
|
7-(2,6-dimethylphenyl)-4-(4-methylpiperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C21H25N5
|
1
|
| 1 |
Ki = 90 nM
|
|
|
|
CP0523773
|
8-methyl-4-(4-methylpiperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C14H19N5
|
1
|
| 1 |
Ki = 91 nM
|
|
|
|
CP0074914
|
[(3aR,6aS)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(5-fluoro-4-methyl-1H-benzimidazol-2-yl)methanone
Show/Hide
|
C16H19FN4O
|
1
|
| 1 |
Ki = 97 nM
|
|
|
|
CP0503455
|
4-tert-butyl-1-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
|
C12H19N5
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0380345
|
3-((1H-imidazol-4-yl)methyl)pyridine
Show/Hide
|
C9H9N3
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0416308
|
(7-fluoro-1H-indol-2-yl)-piperazin-1-ylmethanone
Show/Hide
|
C13H14FN3O
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0530162
|
(5-chloro-7-fluoro-1H-indol-2-yl)-[3-(methylamino)azetidin-1-yl]methanone
Show/Hide
|
C13H13ClFN3O
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0401912
|
6-chloro-N-[(4-fluorophenyl)methyl]-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C20H21ClFN5
|
1
|
| 1 |
Ki = 104.71 nM
|
|
|
|
CP0429211
|
6-chloro-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C13H16ClN5
|
1
|
| 1 |
Ki = 104.71 nM
|
|
|
|
CP0496647
|
6-chloro-2-(4-methylpiperazin-1-yl)-N-(1,3-thiazol-2-ylmethyl)quinazolin-4-amine
Show/Hide
|
C17H19ClN6S
|
1
|
| 1 |
Ki = 104.71 nM
|
|
|
|
CP0450385
|
6-chloro-2-(4-methylpiperazin-1-yl)-N-(1,3-thiazol-5-ylmethyl)quinazolin-4-amine
Show/Hide
|
C17H19ClN6S
|
1
|
| 1 |
Ki = 107.15 nM
|
|
|
|
CP0508919
|
8-(furan-3-yl)-4-(4-methylpiperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C17H19N5O
|
1
|
| 1 |
Ki = 109 nM
|
|
|
|
CP0452069
|
8-bromo-4-(4-methylpiperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C13H16BrN5
|
1
|
| 1 |
Ki = 111 nM
|
|
|
|
CP0859147
|
3-(1H-imidazol-4-yl)propyl N'-4-cyanobenzyl-N-cyclohexylcarbamimidothioate dihydrobromide
Show/Hide
|
C21H28BrN5S
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0381202
|
4-[[[6-chloro-2-(4-methylpiperazin-1-yl)quinazolin-4-yl]amino]methyl]benzonitrile
Show/Hide
|
C21H21ClN6
|
1
|
| 1 |
Ki = 128.82 nM
|
|
|
|
CP0072184
|
[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(4,5-difluoro-1H-benzimidazol-2-yl)methanone
Show/Hide
|
C15H16F2N4O
|
1
|
| 1 |
Ki = 134 nM
|
|
|
|
CP0524316
|
6-chloro-N-[(5-methylfuran-2-yl)methyl]-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C19H22ClN5O
|
1
|
| 1 |
Ki = 134.9 nM
|
|
|
|
CP0917429
|
3-(1H-imidazol-4-yl)propyl N-cyclohexyl-N'-(4-nitrobenzyl)carbamimidothioate dihydrobromide
Show/Hide
|
C20H28BrN5O2S
|
1
|
| 1 |
Ki = 134.9 nM
|
|
|
|
CP0953489
|
6-chloro-N-methyl-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)quinazolin-4-amine
Show/Hide
|
C16H20ClN5
|
1
|
| 1 |
Ki = 141.25 nM
|
|
|
|
CP0541921
|
4-(2-cyclohexylethyl)-1-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
|
C16H25N5
|
1
|
| 1 |
Ki = 141.25 nM
|
|
|
|
CP0891661
|
3-(1H-imidazol-4-yl)propyl N-cyclohexyl-N'-(3,4-dichlorobenzyl)carbamimidothioate dihydrobromide
Show/Hide
|
C20H27BrCl2N4S
|
1
|
| 1 |
Ki = 147.91 nM
|
|
|
|
CP0419000
|
2-[(8aS)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-6-chloro-N-methylquinazolin-4-amine
Show/Hide
|
C16H20ClN5
|
1
|
| 1 |
Ki = 154.88 nM
|
|
|
|
CP0428692
|
(6-chloro-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C14H16ClN3O
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0537100
|
(4-hydroxy-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C14H17N3O2
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0502233
|
4-benzyl-1-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
|
C15H17N5
|
1
|
| 1 |
Ki = 181.97 nM
|
|
|
|
CP0393215
|
6-chloro-N-[(3,4-difluorophenyl)methyl]-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C20H20ClF2N5
|
1
|
| 1 |
Ki = 186.21 nM
|
|
|
|
CP0429210
|
6-chloro-N-(furan-2-ylmethyl)-8-methyl-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C19H22ClN5O
|
1
|
| 1 |
Ki = 186.21 nM
|
|
|
|
CP0074915
|
[(3aR,6aS)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(1H-benzimidazol-2-yl)methanone
Show/Hide
|
C15H18N4O
|
1
|
| 1 |
Ki = 189 nM
|
|
|
|
CP0399066
|
4-(4-methylpiperazin-1-yl)-6-phenylpyrimidine
Show/Hide
|
C15H18N4
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0025667
|
2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone
Show/Hide
|
C18H19ClN4
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0537107
|
(5-chloro-7-methyl-1H-indol-2-yl)-[3-(methylamino)azetidin-1-yl]methanone
Show/Hide
|
C14H16ClN3O
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0390750
|
N-(2,3-dihydro-1H-inden-2-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-4-amine
Show/Hide
|
C18H23N5
|
1
|
| 1 |
Ki = 212 nM
|
|
|
|
CP0074913
|
[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(6-chloro-1H-benzimidazol-2-yl)methanone
Show/Hide
|
C15H17ClN4O
|
1
|
| 1 |
Ki = 218 nM
|
|
|
|
CP0508918
|
8-(2,6-dimethylphenyl)-4-(4-methylpiperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C21H25N5
|
1
|
| 1 |
Ki = 221 nM
|
|
|
|
CP0401909
|
6-fluoro-N-(furan-2-ylmethyl)-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C18H20FN5O
|
1
|
| 1 |
Ki = 223.87 nM
|
|
|
|
CP0875996
|
3-(1H-imidazol-4-yl)propyl N-benzyl-N'-(4-chlorobenzyl)carbamimidothioate dihydrobromide
Show/Hide
|
C21H24BrClN4S
|
1
|
| 1 |
Ki = 229.09 nM
|
|
|
|
CP0488525
|
6-chloro-2-(4-methylpiperazin-1-yl)-N-(2-phenylethyl)quinazolin-4-amine
Show/Hide
|
C21H24ClN5
|
1
|
| 1 |
Ki = 239.88 nM
|
|
|
|
CP0487587
|
1-cycloheptyl-4-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
|
C15H23N5
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0428694
|
(4-fluoro-1H-indol-2-yl)-(4-methyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C15H18FN3O
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0498293
|
(5-chloro-1-benzofuran-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C14H15ClN2O2
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0521649
|
(5-chloro-7-fluoro-1H-indol-2-yl)-[(3R)-3-(methylamino)pyrrolidin-1-yl]methanone
Show/Hide
|
C14H15ClFN3O
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0526092
|
(5-chloro-7-methyl-1H-indol-2-yl)-[(3R)-3-(methylamino)pyrrolidin-1-yl]methanone
Show/Hide
|
C15H18ClN3O
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0499287
|
N-benzyl-6-chloro-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C20H22ClN5
|
1
|
| 1 |
Ki = 257.04 nM
|
|
|
|
CP0450386
|
N-(1-benzothiophen-2-ylmethyl)-6-chloro-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C22H22ClN5S
|
1
|
| 1 |
Ki = 269.15 nM
|
|
|
|
CP0493903
|
6-chloro-2-(4-methylpiperazin-1-yl)-3-phenylmethoxyquinoxaline
Show/Hide
|
C20H21ClN4O
|
1
|
| 1 |
Ki = 269.15 nM
|
|
|
|
CP0549126
|
4-(cyclohexylmethyl)-1-[4-(1H-imidazol-5-yl)butyl]triazole
Show/Hide
|
C16H25N5
|
1
|
| 1 |
Ki = 275.42 nM
|
|
|
|
CP0416306
|
(4-amino-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C14H18N4O
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0432713
|
4-(4-methylpiperazin-1-yl)quinazoline
Show/Hide
|
C13H16N4
|
1
|
| 1 |
Ki = 328 nM
|
|
|
|
CP0401984
|
6-chloro-N-[(4-methoxyphenyl)methyl]-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C21H24ClN5O
|
1
|
| 1 |
Ki = 363.08 nM
|
|
|
|
CP0501893
|
6-chloro-N-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C17H20ClN7O
|
1
|
| 1 |
Ki = 371.54 nM
|
|
|
|
CP0503460
|
1-(2-cyclohexylethyl)-4-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
|
C16H25N5
|
1
|
| 1 |
Ki = 380.19 nM
|
|
|
|
CP0873064
|
3-(1H-imidazol-4-yl)propyl N-benzyl-N'-(3,4-dichlorobenzyl)carbamimidothioate dihydrobromide
Show/Hide
|
C21H23BrCl2N4S
|
1
|
| 1 |
Ki = 380.19 nM
|
|
|
|
CP0435843
|
(7-fluoro-1H-indol-2-yl)-[3-(methylamino)azetidin-1-yl]methanone
Show/Hide
|
C13H14FN3O
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0444932
|
(5-chloro-7-nitro-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C14H15ClN4O3
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0489245
|
[3-(methylamino)azetidin-1-yl]-(7-methyl-1H-indol-2-yl)methanone
Show/Hide
|
C14H17N3O
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0489246
|
(7-fluoro-1H-indol-2-yl)-(4-methyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C15H18FN3O
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0494038
|
1H-indol-2-yl-(4-methyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C15H19N3O
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0502557
|
1-[(3,4-dichlorophenyl)methyl]-4-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
|
C15H15Cl2N5
|
1
|
| 1 |
Ki = 446.68 nM
|
|
|
|
CP0503459
|
1-benzyl-4-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
|
C15H17N5
|
1
|
| 1 |
Ki = 446.68 nM
|
|
|
|
CP0441269
|
4-heptyl-1-[3-(1H-imidazol-5-yl)propyl]triazole
Show/Hide
|
C15H25N5
|
1
|
| 1 |
Ki = 457.09 nM
|
|
|
|
CP0530161
|
(7-fluoro-1H-indol-2-yl)-[(3R)-3-(methylamino)pyrrolidin-1-yl]methanone
Show/Hide
|
C14H16FN3O
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0456415
|
6-N-(3,3-dimethylbutyl)-4-N-[(3S)-pyrrolidin-3-yl]pyrimidine-4,6-diamine
Show/Hide
|
C14H25N5
|
2
|
| 1 |
Ki = 502 nM
|
|
|
| 2 |
Ki = 572 nM
|
|
|
|
CP0401911
|
N-[(4-aminophenyl)methyl]-6-chloro-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C20H23ClN6
|
1
|
| 1 |
Ki = 562.34 nM
|
|
|
|
CP0376371
|
2-[[6-chloro-2-(4-methylpiperazin-1-yl)quinazolin-4-yl]amino]ethanol
Show/Hide
|
C15H20ClN5O
|
1
|
| 1 |
Ki = 575.44 nM
|
|
|
|
CP0376370
|
6-chloro-N-(cyclohexylmethyl)-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C20H28ClN5
|
1
|
| 1 |
Ki = 588.84 nM
|
|
|
|
CP0502556
|
4-(cyclopentylmethyl)-1-[2-(1H-imidazol-5-yl)ethyl]triazole
Show/Hide
|
C13H19N5
|
1
|
| 1 |
Ki = 588.84 nM
|
|
|
|
CP0847316
|
4-(2-(1H-Imidazol-5-yl)ethyl)-1-(cyclohexylmethyl)-1H-1,2,3-triazole dihydrochloride
Show/Hide
|
C14H23Cl2N5
|
1
|
| 1 |
Ki = 588.84 nM
|
|
|
|
CP0460981
|
N-(furan-2-ylmethyl)-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C18H21N5O
|
1
|
| 1 |
Ki = 602.56 nM
|
|
|
|
CP0099745
|
4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imidazole
Show/Hide
|
C16H18N2O2
|
2
|
| 1 |
Ki = 612 nM
|
|
|
| 2 |
Ki = 1862.09 nM
|
|
|
|
CP0479504
|
6-chloro-N,N-dimethyl-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C15H20ClN5
|
1
|
| 1 |
Ki = 616.6 nM
|
|
|
|
CP0412519
|
6-chloro-2-(4-methylpiperazin-1-yl)quinoline
Show/Hide
|
C14H16ClN3
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0468607
|
N-benzyl-2-(1H-imidazol-5-yl)ethanamine
Show/Hide
|
C12H15N3
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0521645
|
[(3R)-3-(methylamino)pyrrolidin-1-yl]-(7-methyl-1H-indol-2-yl)methanone
Show/Hide
|
C15H19N3O
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0467502
|
6-methyl-4-(4-methylpiperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C14H19N5
|
1
|
| 1 |
Ki = 649 nM
|
|
|
|
CP0387982
|
1-[3-[2-amino-4-(4-methylpiperazin-1-yl)quinazolin-8-yl]phenyl]ethanone
Show/Hide
|
C21H23N5O
|
1
|
| 1 |
Ki = 676 nM
|
|
|
|
CP0393214
|
N,5-dimethyl-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C15H21N5
|
1
|
| 1 |
Ki = 691.83 nM
|
|
|
|
CP0381149
|
6-chloro-2-(4-methylpiperazin-1-yl)-N-propan-2-ylquinazolin-4-amine
Show/Hide
|
C16H22ClN5
|
1
|
| 1 |
Ki = 758.58 nM
|
|
|
|
CP0378095
|
(4-methylpiperazin-1-yl)-(7-nitro-1H-indol-2-yl)methanone
Show/Hide
|
C14H16N4O3
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0438384
|
(4-methylpiperazin-1-yl)-(4-nitro-1H-indol-2-yl)methanone
Show/Hide
|
C14H16N4O3
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0502234
|
4-benzyl-1-[4-(1H-imidazol-5-yl)butyl]triazole
Show/Hide
|
C16H19N5
|
1
|
| 1 |
Ki = 912.01 nM
|
|
|
|
CP0496007
|
8-(4-methoxyphenyl)-4-(4-methylpiperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C20H23N5O
|
1
|
| 1 |
Ki = 945 nM
|
|
|
|
CP0382917
|
ethyl 2-[[6-chloro-2-(4-methylpiperazin-1-yl)quinazolin-4-yl]amino]acetate
Show/Hide
|
C17H22ClN5O2
|
1
|
| 1 |
Ki = 954.99 nM
|
|
|
|
CP0401908
|
7-chloro-N-methyl-2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C14H18ClN5
|
1
|
| 1 |
Ki = 954.99 nM
|
|
|
|
CP0192798
|
(5-Methoxy-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C15H19N3O2
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0428715
|
(4-methoxy-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C15H19N3O2
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0566479
|
(4-methylpiperazin-1-yl)-[7-(trifluoromethyl)-1H-indol-2-yl]methanone
Show/Hide
|
C15H16F3N3O
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0501892
|
Benzyl-[2-(4-methyl-piperazin-1-yl)-quinazolin-4-yl]-amine
Show/Hide
|
C20H23N5
|
1
|
| 1 |
Ki = 1071.52 nM
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CP0502554
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4-(1-cyclohexylethyl)-1-[2-(1H-imidazol-5-yl)ethyl]triazole
Show/Hide
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C15H23N5
|
1
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| 1 |
Ki = 1148.15 nM
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CP0502555
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4-benzyl-1-[2-(1H-imidazol-5-yl)ethyl]triazole
Show/Hide
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C14H15N5
|
1
|
| 1 |
Ki = 1148.15 nM
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CP0401907
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2-(4-methylpiperazin-1-yl)-N-(2-phenylethyl)quinazolin-4-amine
Show/Hide
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C21H25N5
|
1
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| 1 |
Ki = 1479.11 nM
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CP0521648
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(4-methyl-1,4-diazepan-1-yl)-(7-methyl-1H-indol-2-yl)methanone
Show/Hide
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C16H21N3O
|
1
|
| 1 |
Ki = 1584.89 nM
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CP0469139
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1-[[1-[3-(1H-imidazol-5-yl)propyl]triazol-4-yl]methyl]piperidine
Show/Hide
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C14H22N6
|
1
|
| 1 |
Ki = 1819.7 nM
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CP0378092
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(4-methylpiperazin-1-yl)-(1H-pyrrolo[2,3-b]pyridin-2-yl)methanone
Show/Hide
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C13H16N4O
|
2
|
| 1 |
Ki = 1995.26 nM
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| 2 |
Ki > 29900 nM
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CP0435835
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(4-methylpiperazin-1-yl)-(1H-pyrrolo[2,3-c]pyridin-2-yl)methanone
Show/Hide
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C13H16N4O
|
1
|
| 1 |
Ki = 1995.26 nM
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CP0435839
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(4-methylpiperazin-1-yl)-(6-nitro-1H-indol-2-yl)methanone
Show/Hide
|
C14H16N4O3
|
1
|
| 1 |
Ki = 1995.26 nM
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CP0304519
|
[5-[[3-[[6-(3,3-dimethylbutylamino)pyrimidin-4-yl]amino]pyrrolidin-1-yl]methyl]furan-2-yl]methanol
Show/Hide
|
C20H31N5O2
|
1
|
| 1 |
Ki = 2110 nM
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CP0006016
|
2-(4-methylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C13H17N5
|
1
|
| 1 |
Ki = 2137.96 nM
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CP0393760
|
4-[2-amino-4-(4-methylpiperazin-1-yl)quinazolin-8-yl]benzonitrile
Show/Hide
|
C20H20N6
|
1
|
| 1 |
Ki = 2333 nM
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CP0419895
|
1-carbazol-9-yl-3-(cyclopropylamino)propan-2-ol
Show/Hide
|
C18H20N2O
|
1
|
| 1 |
Ki = 2400 nM
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CP0382931
|
(7-methoxy-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C15H19N3O2
|
1
|
| 1 |
Ki = 2511.89 nM
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CP0489244
|
1-benzothiophen-2-yl-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C14H16N2OS
|
1
|
| 1 |
Ki = 2511.89 nM
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CP0453562
|
2-(4-methylpiperazin-1-yl)-4-phenoxyquinazoline
Show/Hide
|
C19H20N4O
|
1
|
| 1 |
Ki = 2818.38 nM
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CP0392334
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1-methyl-6-(4-methylpiperazin-1-yl)-4-pyrrolidin-1-ylpyrazolo[3,4-d]pyrimidine
Show/Hide
|
C15H23N7
|
1
|
| 1 |
Ki = 2900 nM
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CP0169952
|
[(3aS,6aR)-2-ethyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(6-chloro-1H-benzimidazol-2-yl)methanone
Show/Hide
|
C16H19ClN4O
|
1
|
| 1 |
Ki = 3300 nM
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CP0537099
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(4-methylpiperazin-1-yl)-(1H-pyrrolo[3,2-b]pyridin-2-yl)methanone
Show/Hide
|
C13H16N4O
|
1
|
| 1 |
Ki = 3981.07 nM
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CP0496646
|
2-(4-methylpiperazin-1-yl)-4-phenylmethoxyquinazoline
Show/Hide
|
C20H22N4O
|
1
|
| 1 |
Ki = 4073.8 nM
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|
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CP0388998
|
[(3aR,6aS)-2-propan-2-yl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(6-chloro-1H-benzimidazol-2-yl)methanone
Show/Hide
|
C17H21ClN4O
|
1
|
| 1 |
Ki = 4490 nM
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|
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CP0884652
|
4-(3-(4-(cyclohexylmethyl)-1H-1,2,3-triazol-1-yl)propyl)morpholine fumarate salt
Show/Hide
|
C20H32N4O5
|
1
|
| 1 |
Ki = 4786.3 nM
|
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CP0521647
|
(4-methyl-1,4-diazepan-1-yl)-[7-(trifluoromethyl)-1H-indol-2-yl]methanone
Show/Hide
|
C16H18F3N3O
|
1
|
| 1 |
Ki = 5011.87 nM
|
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|
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CP0537101
|
1-[2-(4-methylpiperazine-1-carbonyl)-1H-indol-4-yl]ethanone
Show/Hide
|
C16H19N3O2
|
1
|
| 1 |
Ki = 5011.87 nM
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CP0428714
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(4-methylpiperazin-1-yl)-(1H-pyrrolo[3,2-c]pyridin-2-yl)methanone
Show/Hide
|
C13H16N4O
|
1
|
| 1 |
Ki = 6309.57 nM
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CP0401982
|
2-(4-methylpiperazin-1-yl)quinazoline
Show/Hide
|
C13H16N4
|
1
|
| 1 |
Ki = 7585.78 nM
|
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CP0292149
|
[(3aS,6aR)-2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl]-(6-chloro-1H-benzimidazol-2-yl)methanone
Show/Hide
|
C14H15ClN4O
|
1
|
| 1 |
Ki = 8180 nM
|
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|
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CP0521432
|
2-(4-methylpiperazin-1-yl)-N-phenylquinazolin-4-amine
Show/Hide
|
C19H21N5
|
1
|
| 1 |
Ki = 8511.38 nM
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CP0475628
|
2-N-(cyclopropylmethyl)-6-[3-(methylamino)azetidin-1-yl]pyrimidine-2,4-diamine
Show/Hide
|
C12H20N6
|
2
|
| 1 |
Ki = 9070 nM
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|
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| 2 |
Ki > 2000 nM
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CP0077617
|
(1R,2S,5S,6S,9R,12S,13R,16S)-N,N,6,7,13-pentamethyl-7-azapentacyclo[10.8.0.0^{2,9}.0^{5,9}.0^{13,18}]icos-18-en-16-amine
Show/Hide
|
C24H40N2
|
1
|
| 1 |
Ki > 10000 nM
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CP0136874
|
(2R)-N,3-dimethyl-2-(methylamino)-N-[(1R,2S,5S,6S,9R,12S,13R,16S)-6,7,13-trimethyl-7-azapentacyclo[10.8.0.0^{2,9}.0^{5,9}.0^{13,18}]icos-18-en-16-yl]butanamide
Show/Hide
|
C29H49N3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0002070
|
1-(1H-Indol-3-yl)-2-propanamine
Show/Hide
|
C11H14N2
|
1
|
| 1 |
Ki > 10000 nM
|
|
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CP0002071
|
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-N-prop-2-enylprop-2-en-1-amine
Show/Hide
|
C17H22N2O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0473959
|
2-[4-[4-[(3aR,6aR)-5-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl]phenyl]phenyl]pyridazin-3-one
Show/Hide
|
C23H24N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0503456
|
1-[3-[4-(cyclohexylmethyl)triazol-1-yl]propyl]piperidine
Show/Hide
|
C17H30N4
|
1
|
| 1 |
Ki = 11220.18 nM
|
|
|
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CP0305101
|
(6-chloroimidazo[1,2-a]pyridin-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C13H15ClN4O
|
1
|
| 1 |
Ki > 11400 nM
|
|
|
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CP0494037
|
1-[2-(4-methylpiperazine-1-carbonyl)-1H-indol-5-yl]ethanone
Show/Hide
|
C16H19N3O2
|
1
|
| 1 |
Ki = 12589.25 nM
|
|
|
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CP0401983
|
6-chloro-2-(4-methylpiperazin-1-yl)-3H-quinazolin-4-one
Show/Hide
|
C13H15ClN4O
|
1
|
| 1 |
Ki = 15135.61 nM
|
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|
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CP0469140
|
1-[[1-[3-(1H-imidazol-5-yl)propyl]triazol-4-yl]methyl]-4-methylpiperazine
Show/Hide
|
C14H23N7
|
1
|
| 1 |
Ki = 15135.61 nM
|
|
|
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CP0446959
|
(7-methoxy-1H-indol-2-yl)-(4-methyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C16H21N3O2
|
1
|
| 1 |
Ki = 15848.93 nM
|
|
|
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CP0450328
|
(6-methoxy-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C15H19N3O2
|
1
|
| 1 |
Ki = 15848.93 nM
|
|
|
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CP0503441
|
imidazo[1,2-a]pyrazin-2-yl-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C12H15N5O
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
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CP0407950
|
1-(4-methylpiperazin-1-yl)isoquinoline
Show/Hide
|
C14H17N3
|
1
|
| 1 |
Ki = 20400 nM
|
|
|
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CP0378016
|
1-[3-[4-(cyclohexylmethyl)triazol-1-yl]propyl]-4-methylpiperazine
Show/Hide
|
C17H31N5
|
1
|
| 1 |
Ki = 20892.96 nM
|
|
|
|
CP0503458
|
4-(cyclohexylmethyl)-1-(3-imidazol-1-ylpropyl)triazole
Show/Hide
|
C15H23N5
|
1
|
| 1 |
Ki = 21877.62 nM
|
|
|
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CP0920208
|
1-((1-(3-(piperidin-1-yl)propyl)-1H-1,2,3-triazol-4-yl)methyl)piperidine fumarate salt
Show/Hide
|
C20H33N5O4
|
1
|
| 1 |
Ki = 38904.51 nM
|
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CP0544247
|
2-[3-(dimethylamino)-6-dimethylazaniumylidenexanthen-9-yl]-5-[2-[2-[2-[2-[[1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperidine-4-carbonyl]amino]ethoxy]ethoxy]ethoxy]ethylcarbamoyl]benzoate
Show/Hide
|
C54H70N6O9
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
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CP0372872
|
6-chloro-N-methyl-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)quinazolin-4-amine
Show/Hide
|
C19H26ClN5
|
1
|
| 1 |
Ki > 1000 nM
|
|
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CP0372873
|
6-chloro-4-N-methyl-2-N-[(1-methylpiperidin-4-yl)methyl]quinazoline-2,4-diamine
Show/Hide
|
C16H22ClN5
|
1
|
| 1 |
Ki > 1000 nM
|
|
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CP0401987
|
2-[(3S)-3-aminopyrrolidin-1-yl]-6-chloro-N-methylquinazolin-4-amine
Show/Hide
|
C13H16ClN5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
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CP0401990
|
6-chloro-N-methyl-2-(7-methyl-2,7-diazaspiro[4.4]nonan-2-yl)quinazolin-4-amine
Show/Hide
|
C17H22ClN5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0412882
|
2-(1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl)-6-chloro-N-methylquinazolin-4-amine
Show/Hide
|
C16H20ClN5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0418999
|
6-chloro-2-(2,4-dimethylpiperazin-1-yl)-N-methylquinazolin-4-amine
Show/Hide
|
C15H20ClN5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
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CP0479569
|
6-chloro-4-N-methyl-2-N-[2-(1-methylpyrrolidin-3-yl)ethyl]quinazoline-2,4-diamine
Show/Hide
|
C16H22ClN5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0496648
|
6-chloro-N-methyl-2-(3,4,5-trimethylpiperazin-1-yl)quinazolin-4-amine
Show/Hide
|
C16H22ClN5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0496649
|
2-[(3aS,6aR)-2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl]-6-chloro-N-methylquinazolin-4-amine
Show/Hide
|
C15H18ClN5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0497910
|
6-chloro-N-methyl-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
Show/Hide
|
C15H20ClN5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0536235
|
2-[(3R)-3-aminopyrrolidin-1-yl]-6-chloro-N-methylquinazolin-4-amine
Show/Hide
|
C13H16ClN5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0536236
|
6-chloro-4-N-methyl-2-N-[(1-methylpyrrolidin-3-yl)methyl]quinazoline-2,4-diamine
Show/Hide
|
C15H20ClN5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0547842
|
6-chloro-N-methyl-2-[2-[(4-methylpiperazin-1-yl)methyl]pyrrolidin-1-yl]quinazolin-4-amine
Show/Hide
|
C19H27ClN6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0921390
|
(S)-6-chloro-2-(hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-N-methylquinazolin-4-amine
Show/Hide
|
C14H18ClN5
|
1
|
| 1 |
Ki > 1000 nM
|
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|
