Brief Information of the Compound and Protein
Compound Name
2-[(3aS,6aR)-2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl]-6-chloro-N-methylquinazolin-4-amine
    Show/Hide
PubChem ID
CID: 25178758
Canonical SMILES
CNc1nc(nc2ccc(Cl)cc12)N1C[C@@H]2CNC[C@@H]2C1
    Show/Hide
Compound Formula C15H18ClN5
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS