General Information of the Compound
| Compound ID |
CP0381149
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| Compound Name |
6-chloro-2-(4-methylpiperazin-1-yl)-N-propan-2-ylquinazolin-4-amine
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| Structure |
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| Formula |
C16H22ClN5
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| Molecular Weight |
319.84
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| Canonical SMILES |
CC(C)Nc1nc(nc2ccc(Cl)cc12)N1CCN(C)CC1
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| InChI |
InChI=1S/C16H22ClN5/c1-11(2)18-15-13-10-12(17)4-5-14(13)19-16(20-15)22-8-6-21(3)7-9-22/h4-5,10-11H,6-9H2,1-3H3,(H,18,19,20)
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| InChIKey |
GGBKKIVDGBAYTK-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02227, 5-hydroxytryptamine receptor 3A
Protein ID: PT01711, Histamine H4 receptor