Brief Information of the Compound and Protein
Compound Name
7-ethyl-4-[3-(methylamino)azetidin-1-yl]pyrido[3,2-d]pyrimidin-2-amine
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PubChem ID
CID: 71525678
SID: 163518854
Canonical SMILES
CCc1cnc2c(nc(N)nc2c1)N1CC(C1)NC
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Compound Formula C13H18N6
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
IC50 = 112.2 nM
   TI
   LI
   LO
   TS
2
Kd = 8.511 nM
   TI
   LI
   LO
   TS
3
Ki = 10.72 nM
   TI
   LI
   LO
   TS