General Information of the Compound
| Compound ID |
CP0851247
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| Compound Name |
1-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-1H-pyridin-2-one
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| Structure |
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| Formula |
C14H18N6O
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| Molecular Weight |
286.339
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| Canonical SMILES |
CN1CCN(c2cc(-n3ccccc3=O)nc(N)n2)CC1
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| InChI |
InChI=1S/C14H18N6O/c1-18-6-8-19(9-7-18)11-10-12(17-14(15)16-11)20-5-3-2-4-13(20)21/h2-5,10H,6-9H2,1H3,(H2,15,16,17)
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| InChIKey |
OJHQVXKWXRZSKG-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01711, Histamine H4 receptor
Protein ID: PT02519, Histamine H4 receptor