Brief Information of the Compound and Protein
Compound Name
3-(1H-imidazol-5-yl)propyl N'-[(4-chlorophenyl)methyl]-N-cyclohexylcarbamimidothioate
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PubChem ID
CID: 10023327
SID: 15004827
Canonical SMILES
Clc1ccc(CN=C(NC2CCCCC2)SCCCc2cnc[nH]2)cc1
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Compound Formula C20H27ClN4S
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  5
1
Ki = 12.59 nM
   TI
   LI
   LO
   TS
2
Ki = 47.86 nM
   TI
   LI
   LO
   TS
3
Ki = 63.1 nM
   TI
   LI
   LO
   TS
4
Ki = 158.49 nM
   TI
   LI
   LO
   TS
5
Ki = 316.23 nM
   TI
   LI
   LO
   TS