Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(5,6-difluoro-1H-benzimidazol-2-yl)methanone
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 PubChem ID
CID: 57395538
Canonical SMILES
CN1C[C@H]2CN(C[C@H]2C1)C(=O)c1nc2cc(F)c(F)cc2[nH]1
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Compound Formula C15H16F2N4O
Compound Structure
Protein Name
 Protein Info 
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 128 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
Ki = 53 nM
   TI
   LI
   LO
   TS
2
Ki = 128 nM
   TI
   LI
   LO
   TS
3
Ki = 236 nM
   TI
   LI
   LO
   TS