Brief Information of the Compound and Protein
Compound Name
2-N-(cyclopropylmethyl)-6-[3-(methylamino)azetidin-1-yl]pyrimidine-2,4-diamine
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PubChem ID
CID: 57390344
Canonical SMILES
CNC1CN(C1)c1cc(N)nc(NCC2CC2)n1
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Compound Formula C12H20N6
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
Ki = 9070 nM
   TI
   LI
   LO
   TS
2
Ki > 2000 nM
   TI
   LI
   LO
   TS