Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-N-(3,3-dimethylbutyl)-4-N-[(3S)-pyrrolidin-3-yl]pyrimidine-4,6-diamine
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 PubChem ID
CID: 57395620
Canonical SMILES
CC(C)(C)CCNc1cc(N[C@H]2CCNC2)ncn1
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Compound Formula C14H25N5
Compound Structure
Protein Name
 Protein Info 
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 502 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
Ki = 502 nM
   TI
   LI
   LO
   TS
2
Ki = 572 nM
   TI
   LI
   LO
   TS