| Compound ID |
Compound Name |
Compound Formula |
|
CP0657489
|
(3S,5Z,8S,9R,11E)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,9,10-tetrahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione
Show/Hide
|
C19H22O7
|
1
|
| 1 |
IC50 = 0.49 nM
|
|
|
|
CP0402143
|
1-[2-Chloro-4-({5-[2-(2-hydroxyethoxy)ethyl]-5H-pyrrolo [3,2-d]pyrimidin-4-yl}oxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C24H21ClF3N5O4
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0434832
|
1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-[4-(trifluoromethyl)pyridin-2-yl]urea
Show/Hide
|
C20H14ClF3N6O2
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0372739
|
1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-[5-(trifluoromethyl)pyridin-3-yl]urea
Show/Hide
|
C20H14ClF3N6O2
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0191521
|
N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-3-(2-fluorophenyl)-2-oxoimidazolidine-1-carboxamide
Show/Hide
|
C28H22F2N6O3S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0493069
|
N-[3-fluoro-4-[2-[4-[[methyl-[2-(4-methylpiperazin-1-yl)ethyl]amino]methyl]phenyl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C38H40FN7O3S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0018477
|
4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide
Show/Hide
|
C21H16ClF3N4O3
|
6
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
| 3 |
IC50 = 42 nM
|
|
|
| 4 |
IC50 = 100 nM
|
|
|
| 5 |
IC50 = 950 nM
|
|
|
| 6 |
IC50 = 1210 nM
|
|
|
|
CP0146525
|
1-(2-chloro-4-(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yloxy)phenyl)-3-(3-(trifluoromethyl)phenyl)urea
Show/Hide
|
C21H15ClF3N5O2
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0489456
|
1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-[2-(trifluoromethyl)pyridin-4-yl]urea
Show/Hide
|
C20H14ClF3N6O2
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0534044
|
N'-[3-fluoro-4-[2-(pyrrolidine-1-carbonyl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-N-phenylpropanediamide
Show/Hide
|
C27H23FN4O4S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0497213
|
1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-[1-(2,2,2-trifluoroethyl)-1H-pyrazol-4-yl]urea
Show/Hide
|
C19H15ClF3N7O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0504641
|
1-(2-Chloro-4-{[5-(2-hydroxyethyl)-5H-pyrrolo[3,2-d]pyrim idin-4-yl]oxy}phenyl)-3-[3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C22H17ClF3N5O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0014985
|
BIBF-1120
Show/Hide
|
C31H33N5O4
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0473815
|
N'-[4-[2-(1-ethylimidazole-4-carbonyl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-N-phenylpropanediamide
Show/Hide
|
C28H22FN5O4S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0490708
|
N'-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-N-(4-fluorophenyl)propanediamide
Show/Hide
|
C27H21F2N5O3S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0036099
|
1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methyl-phenyl)urea
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|
C21H18FN5O
|
3
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 7 nM
|
|
|
| 3 |
IC50 = 8.404 nM
|
|
|
|
CP0043225
|
4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
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|
C21H15ClF4N4O3
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0674914
|
(Z)-3-({4-[(2-Imidazol-1-yl-acetyl)methylamino]-phenylamino}-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acidMethyl Ester
Show/Hide
|
C29H25N5O4
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0457425
|
N'-[4-[2-[1-[2-(dimethylamino)ethyl]imidazole-4-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-N-phenylpropanediamide
Show/Hide
|
C30H27FN6O4S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0473814
|
N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-N'-methyl-N'-phenylpropanediamide
Show/Hide
|
C28H24FN5O3S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0506489
|
N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-N'-(2-methoxyphenyl)propanediamide
Show/Hide
|
C28H24FN5O4S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0173202
|
1-[3-(3-amino-1H-indazol-4-yl)phenyl]-3-(3-propan-2-ylphenyl)urea
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|
C23H23N5O
|
1
|
| 1 |
IC50 = 6.86 nM
|
|
|
|
CP0731426
|
(Z)-6-Nitro-3-[phenyl-(4-piperidin-1-ylmethyl-phenylamino)-methylene]-indolin-2-one
Show/Hide
|
C27H26N4O3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0137418
|
N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-3-(4-fluorophenyl)-2-oxoimidazolidine-1-carboxamide
Show/Hide
|
C28H22F2N6O3S
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0404718
|
N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-N'-(2-hydroxyphenyl)propanediamide
Show/Hide
|
C27H22FN5O4S
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0017324
|
N-[5-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]-3-methylphenyl]-1H-pyrazol-3-yl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide
Show/Hide
|
C31H38N8O3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0382323
|
1-[4-[2-[[6-(3-aminopyrrolidin-1-yl)-2-methylpyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]-3-(5-ethyl-1,2-oxazol-3-yl)urea
Show/Hide
|
C24H27N9O2S
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0415352
|
1-(1-tert-Butyl-1H-pyrazol-4-yl)-3-{2-chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}urea
Show/Hide
|
C21H22ClN7O2
|
1
|
| 1 |
IC50 = 7.6 nM
|
|
|
|
CP0710220
|
(Z)-3-{[4-(N-Acetyl-dimethylcarbamoylmethyl-amino)-phenylamino]-phenyl-methylene}-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid Methyl Ester
Show/Hide
|
C29H28N4O5
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0191525
|
4-(4-(7-(2-fluoro-4-(2-oxo-3-phenylimidazolidine-1-carboxamido)phenoxy)thieno[3,2-b]pyridin-2-yl)benzyl)-N-methylpiperazine-1-carboxamide
Show/Hide
|
C36H34FN7O4S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0195511
|
N-[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C27H21FN6O3S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0296656
|
N-[3-fluoro-4-[2-[1-(3-pyrrolidin-1-ylpropyl)imidazol-4-yl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C33H32FN7O3S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0022314
|
1-N'-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-1-N-phenylcyclopropane-1,1-dicarboxamide
Show/Hide
|
C29H24FN5O3S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0523867
|
1-(5-tert-butylisoxazol-3-yl)-3-(2-chloro-4-(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yloxy)phenyl)urea
Show/Hide
|
C21H21ClN6O3
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0710221
|
(Z)-3-({4-[N-Acetyl-(3-dimethylaminopropyl)-amino]-phenylamino}-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid Methyl Ester
Show/Hide
|
C30H32N4O4
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0218988
|
3-(3-fluoro-4-{[2-(pyrrolidin-1-ylcarbonyl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
|
C27H23FN4O3S2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0313455
|
1-N'-[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-1-N-phenylcyclopropane-1,1-dicarboxamide
Show/Hide
|
C28H22FN5O3S
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0508229
|
1-(2-Chloro-4-{[5-(2-methoxyethyl)-5H-pyrrolo[3,2-d]pyr imidin-4-yl]oxy}phenyl)-3-[3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C23H19ClF3N5O3
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0434815
|
1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}urea
Show/Hide
|
C27H27ClF3N7O2
|
1
|
| 1 |
IC50 = 9.3 nM
|
|
|
|
CP0427787
|
1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-[4-methoxy-3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C22H17ClF3N5O3
|
1
|
| 1 |
IC50 = 9.4 nM
|
|
|
|
CP0427791
|
1-(2-Chloro-4-{[6-(hydroxymethyl)-5-methyl-5H-pyrrolo [3,2-d]pyrimidin-4-yl]oxy}phenyl)-3-[3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C22H17ClF3N5O3
|
1
|
| 1 |
IC50 = 9.7 nM
|
|
|
|
CP0091889
|
3-(3-fluoro-4-{[2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
|
C26H20FN5O2S2
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 26 nM
|
|
|
|
CP0161600
|
3-(3-fluoro-4-{[2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
|
C26H20FN5O2S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0297743
|
N-[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-N'-methyl-N'-phenylpropanediamide
Show/Hide
|
C27H22FN5O3S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0495715
|
N-cyclohexyl-N'-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]propanediamide
Show/Hide
|
C27H28FN5O3S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0534043
|
N'-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-N-(3-fluorophenyl)propanediamide
Show/Hide
|
C27H21F2N5O3S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0158203
|
4,4,4-trifluoro-3-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylamino)-N-phenylbutanamide
Show/Hide
|
C27H21F4N5O2S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0381558
|
1-(5-ethyl-1,2-oxazol-3-yl)-3-[4-[2-[[2-methyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]urea
Show/Hide
|
C25H29N9O2S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0073709
|
3-(4-{[2-(1-ethyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy}-3-fluorophenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
|
C27H22FN5O2S2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0253784
|
N-[3-fluoro-4-[2-[4-(piperazin-1-ylmethyl)phenyl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C34H31FN6O3S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0373643
|
1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-{3-[(4-methylpiperazin-1-yl)methyl]-5-(trifluoromethyl)phenyl}urea
Show/Hide
|
C27H27ClF3N7O2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0675761
|
(Z)-3-({4-[N-Acetyl-(2-dimethylaminoethyl)-amino]-phenylamino}-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid Methyl Ester
Show/Hide
|
C29H30N4O4
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0253734
|
N-[3-fluoro-4-[2-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C35H33FN6O3S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0282510
|
N-[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-3-phenylimidazolidine-1-carbothioamide
Show/Hide
|
C27H21FN6O2S2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0350474
|
N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C28H23FN6O3S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0415380
|
1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-{4-[(1-methylpiperidin-4-yl)oxy]-3-(trifluoromethyl)phenyl}urea
Show/Hide
|
C27H26ClF3N6O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0381459
|
1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[[4-[3-[[2-methyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1H-pyrazol-5-yl]phenyl]methyl]urea
Show/Hide
|
C28H36N10O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0397497
|
N-[5-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-1H-pyrazol-3-yl]-4-(2-pyrrolidin-1-ylethoxy)benzamide
Show/Hide
|
C30H35N7O4
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0409663
|
N-[5-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide
Show/Hide
|
C29H34N8O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0429466
|
N-[5-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-1H-pyrazol-3-yl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide
Show/Hide
|
C30H36N8O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0779227
|
SID85147444
Show/Hide
|
C28H24ClF3N4O6S
|
1
|
| 1 |
IC50 = 12.5 nM
|
|
|
|
CP0457426
|
N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-N'-[2-(trifluoromethyl)phenyl]propanediamide
Show/Hide
|
C28H21F4N5O3S
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0242512
|
N-[4-[2-[1-[2-(dimethylamino)ethyl]imidazol-4-yl]thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C30H28FN7O3S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0282509
|
N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-3-(2-methoxyphenyl)-2-oxoimidazolidine-1-carboxamide
Show/Hide
|
C29H25FN6O4S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0504642
|
1-(2-Chloro-4-{[6-(methoxymethyl)-5-methyl-5H-pyrrolo [3,2-d]pyrimidin-4-yl]oxy}phenyl)-3-[3-(trifluoromethyl)phenyl]-urea
Show/Hide
|
C23H19ClF3N5O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0289955
|
N'-[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-N-phenylpropanediamide
Show/Hide
|
C26H20FN5O3S
|
2
|
| 1 |
IC50 = 15 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
|
CP0399926
|
1-N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-1-N'-(2-fluorophenyl)cyclopropane-1,1-dicarboxamide
Show/Hide
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C29H23F2N5O3S
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1
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| 1 |
IC50 = 15 nM
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CP0388688
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1-[4-[2-[[2-methyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]-3-(5-methyl-1,2-oxazol-3-yl)urea
Show/Hide
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C24H27N9O2S
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1
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| 1 |
IC50 = 15 nM
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CP0481520
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1-(5-cyclopropyl-1,2-oxazol-3-yl)-3-[4-[2-[[6-(4-ethylpiperazin-1-yl)-2-methylpyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]urea
Show/Hide
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C27H31N9O2S
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1
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| 1 |
IC50 = 15 nM
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CP0420771
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5-(3,5-dipyridin-2-ylphenyl)-N-(5-ethylsulfonyl-2-methoxyphenyl)-1,3-oxazol-2-amine
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C28H24N4O4S
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1
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| 1 |
IC50 = 15.1 nM
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CP0253787
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N-[3-fluoro-4-[2-(1-propan-2-ylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-1-phenylpyrrolidine-3-carboxamide
Show/Hide
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C30H26FN5O3S
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1
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| 1 |
IC50 = 16 nM
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CP0287471
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3-(3-fluoro-4-{[2-(1,3-thiazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
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C25H17FN4O2S3
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1
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| 1 |
IC50 = 17 nM
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CP0350271
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3-(3-fluoro-4-{[2-(pyridin-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
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C27H19FN4O2S2
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1
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| 1 |
IC50 = 17 nM
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CP0050097
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2-Anilino-5-aryloxazole 39
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C23H21N3O4S
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2
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| 1 |
IC50 = 17.1 nM
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| 2 |
IC50 = 22 nM
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CP0396898
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N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-N'-(2-fluorophenyl)propanediamide
Show/Hide
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C27H21F2N5O3S
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1
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| 1 |
IC50 = 18 nM
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CP0507920
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1-(2-Chloro-4-{[6-(1-hydroxy-1-methylethyl)-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl]oxy}phenyl)-3-[3-(trifluoromethyl)phenyl]urea
Show/Hide
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C24H21ClF3N5O3
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1
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| 1 |
IC50 = 18 nM
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CP0407308
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N-[5-[4-[[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]methyl]phenyl]-1H-pyrazol-3-yl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide
Show/Hide
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C31H38N8O3
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1
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| 1 |
IC50 = 18 nM
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CP0296585
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7-(2-fluoro-4-{[(1-phenylacetamido)methanethioyl]amino}phenoxy)-N,N-dimethylthieno[3,2-b]pyridine-2-carboxamide
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C25H21FN4O3S2
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1
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| 1 |
IC50 = 19 nM
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CP0533326
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2-(4-(7-(2-fluoro-4-(3-oxo-3-(phenylamino)propanamido)phenoxy)thieno[3,2-b]pyridine-2-carbonyl)-1H-imidazol-1-yl)acetic acid
Show/Hide
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C28H20FN5O6S
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1
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| 1 |
IC50 = 19 nM
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CP0371781
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1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-[4-(morpholin-4-ylmethyl)-3-(trifluoromethyl)phenyl]urea
Show/Hide
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C26H24ClF3N6O3
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1
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| 1 |
IC50 = 19 nM
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CP0427786
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1-(3-tert-Butyl-1-methyl-1H-pyrazol-5-yl)-3-{2-chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}urea
Show/Hide
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C22H24ClN7O2
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1
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| 1 |
IC50 = 19 nM
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CP0282279
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N-[3-fluoro-4-[2-[1-(2-pyrrolidin-1-ylethyl)imidazol-4-yl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
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C32H30FN7O3S
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1
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| 1 |
IC50 = 20 nM
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CP0045447
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4,4,4-trifluoro-3-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylamino)-N-(2-methoxyphenyl)butanamide
Show/Hide
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C28H23F4N5O3S
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1
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| 1 |
IC50 = 20 nM
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CP0376373
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4,4,4-trifluoro-3-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylamino)-N-(4-fluorophenyl)butanamide
Show/Hide
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C27H20F5N5O2S
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1
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| 1 |
IC50 = 20 nM
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CP0376375
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4,4,4-trifluoro-N-(4-fluorophenyl)-3-(4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylamino)butanamide
Show/Hide
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C27H21F4N5O2S
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1
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| 1 |
IC50 = 20 nM
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CP0434833
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1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-[3-methoxy-5-(trifluoromethyl)phenyl]urea
Show/Hide
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C22H17ClF3N5O3
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1
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| 1 |
IC50 = 20 nM
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CP0381461
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N-[5-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-1H-pyrazol-3-yl]-4-(2-morpholin-4-ylethoxy)benzamide
Show/Hide
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C30H35N7O5
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1
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| 1 |
IC50 = 22 nM
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CP0674916
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(Z)-3-({4-[(2-Dimethylaminoethyl)-methanesulfonyl-amino]-phenylamino}-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic Acid Methyl Ester
Show/Hide
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C28H30N4O5S
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1
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| 1 |
IC50 = 23 nM
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CP0235561
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(S)-N-(4-(2-(3-(dimethylamino)pyrrolidine-1-carbonyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
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C30H29FN6O4S
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1
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| 1 |
IC50 = 23 nM
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CP0434834
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1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-[3-(morpholin-4-ylmethyl)-5-(trifluoromethyl)phenyl]urea
Show/Hide
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C26H24ClF3N6O3
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1
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| 1 |
IC50 = 23 nM
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CP0674915
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(Z)-3-({4-[(3-Dimethylaminopropyl)-methyl-carbamoyl]-phenylamino}-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid Methyl Ester
Show/Hide
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C29H30N4O4
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1
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| 1 |
IC50 = 24 nM
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CP0208847
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3-(3-fluoro-4-{[2-(1-methyl-1H-pyrazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
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C26H20FN5O2S2
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1
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| 1 |
IC50 = 25 nM
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CP0358346
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3-(4-{[2-(1-ethyl-1H-imidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}-3-fluorophenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
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C27H22FN5O2S2
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1
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| 1 |
IC50 = 25 nM
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CP0641297
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N-(5-ethyl-3-isoxazolyl)-N'-[4-(2-[6-(4-ethylpiperazino)-2-methyl-4-pyrimidinyl]amino-1,3-thiazol-5-yl)phenyl]urea
Show/Hide
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C26H31N9O2S
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1
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| 1 |
IC50 = 25 nM
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CP0383439
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5-bromo-2-N-[(3-methyl-1,2-oxazol-5-yl)methyl]-4-N-[5-(2-phenylethyl)-1H-pyrazol-3-yl]pyrimidine-2,4-diamine
Show/Hide
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C20H20BrN7O
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1
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| 1 |
IC50 = 25.12 nM
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CP0369461
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N-[4-[2-(1-ethylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
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C28H23FN6O3S
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1
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| 1 |
IC50 = 26 nM
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CP0381229
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4-(4-methylpiperazin-1-yl)-N-[5-[4-(phenylcarbamoylamino)phenyl]-1H-pyrazol-3-yl]benzamide
Show/Hide
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C28H29N7O2
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1
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| 1 |
IC50 = 26 nM
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CP0381230
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N-[5-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]-3-methylphenyl]-1H-pyrazol-3-yl]-4-(2-morpholin-4-ylethoxy)benzamide
Show/Hide
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C31H37N7O5
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1
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| 1 |
IC50 = 27 nM
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CP0158811
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3-(3-fluoro-4-{[2-(1-methyl-1H-1,2,4-triazol-5-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
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C25H19FN6O2S2
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1
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| 1 |
IC50 = 28 nM
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CP0016229
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N-[5-[4-[[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]methyl]phenyl]-1H-pyrazol-3-yl]-4-(2-morpholin-4-ylethoxy)benzamide
Show/Hide
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C31H37N7O5
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1
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| 1 |
IC50 = 28 nM
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CP0490706
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N'-[3-fluoro-4-[2-(1-methylimidazole-4-carbonyl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-N-phenylpropanediamide
Show/Hide
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C27H20FN5O4S
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1
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| 1 |
IC50 = 30 nM
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CP0522011
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3-(4-(6,7-dimethoxyquinolin-4-yloxy)-3-fluorophenylamino)-4,4,4-trifluoro-N-phenylbutanamide
Show/Hide
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C27H23F4N3O4
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1
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| 1 |
IC50 = 30 nM
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CP0218991
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3-(3-fluoro-4-{[2-(1-methyl-1H-pyrrol-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
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C27H21FN4O2S2
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1
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| 1 |
IC50 = 31 nM
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CP0350270
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N-[3-fluoro-4-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
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C27H21FN6O3S
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1
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| 1 |
IC50 = 31 nM
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CP0397498
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N-[5-[4-[(5-methyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide
Show/Hide
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C26H28N8O3
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1
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| 1 |
IC50 = 31 nM
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CP0376258
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1-(3-chlorophenyl)-3-[4-[2-[(2-methyl-6-piperazin-1-ylpyrimidin-4-yl)amino]-1,3-thiazol-5-yl]phenyl]urea
Show/Hide
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C25H25ClN8OS
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1
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| 1 |
IC50 = 31 nM
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CP0884487
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sunitinib L-malate
Show/Hide
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C26H33FN4O7
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1
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| 1 |
IC50 = 31.2 nM
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CP0087700
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3-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-1-(2-phenylacetyl)thiourea
Show/Hide
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C26H22FN3O4S
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1
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| 1 |
IC50 = 32 nM
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CP0313647
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3-(3-fluoro-4-{[2-(thiophen-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
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C26H18FN3O2S3
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1
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| 1 |
IC50 = 32 nM
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CP0381228
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4-(4-methylpiperazin-1-yl)-N-[5-[4-[(5-methyl-1,3-thiazol-2-yl)carbamoylamino]phenyl]-1H-pyrazol-3-yl]benzamide
Show/Hide
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C26H28N8O2S
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1
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| 1 |
IC50 = 35 nM
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CP0695291
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(Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenylamino)-methylene]-2,3-dihydro-1H-indole-6-carboxylic Acid Methyl Ester
Show/Hide
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C29H29N3O3
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1
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| 1 |
IC50 = 36 nM
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CP0253783
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N-[[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]carbamoyl]-2-phenylacetamide
Show/Hide
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C26H20FN5O3S
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1
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| 1 |
IC50 = 37 nM
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CP0381457
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1-(3-chlorophenyl)-3-[[4-[3-[(2-methyl-6-piperazin-1-ylpyrimidin-4-yl)amino]-1H-pyrazol-5-yl]phenyl]methyl]urea
Show/Hide
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C26H28ClN9O
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1
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| 1 |
IC50 = 38 nM
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CP0381463
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N-[5-[3-methyl-4-[(5-methyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide
Show/Hide
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C27H30N8O3
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1
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| 1 |
IC50 = 38 nM
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CP0310895
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N-[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-1-phenylpyrrolidine-3-carboxamide
Show/Hide
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C28H22FN5O3S
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1
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| 1 |
IC50 = 39 nM
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CP0010193
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AG-013736
Show/Hide
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C22H18N4OS
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1
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| 1 |
IC50 = 39 nM
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CP0038799
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N-[6-[4-[(4-anilino-1,1,1-trifluoro-4-oxobutan-2-yl)amino]-2-fluorophenoxy]pyrimidin-4-yl]pyrrolidine-1-carboxamide
Show/Hide
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C25H24F4N6O3
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1
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| 1 |
IC50 = 40 nM
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CP0415012
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1-(4-chlorophenyl)-3-[4-[2-[[6-(4-ethylpiperazin-1-yl)-2-methylpyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]urea
Show/Hide
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C27H29ClN8OS
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1
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| 1 |
IC50 = 43 nM
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CP0396897
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N'-[3-fluoro-4-[2-(1-methylimidazole-2-carbonyl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-N-phenylpropanediamide
Show/Hide
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C27H20FN5O4S
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1
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| 1 |
IC50 = 50 nM
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CP0397401
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N-[5-[4-[[(5-methyl-1,2-oxazol-3-yl)carbamoylamino]methyl]phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide
Show/Hide
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C27H30N8O3
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1
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| 1 |
IC50 = 50 nM
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CP0414701
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1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[[4-[3-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1H-pyrazol-5-yl]phenyl]methyl]urea
Show/Hide
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C29H38N10O3
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1
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| 1 |
IC50 = 50 nM
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CP0378419
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EXEL-7647
Show/Hide
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C24H25Cl2FN4O2
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1
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| 1 |
IC50 < 50 nM
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CP0380385
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(3S,9aS)-3-({[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydro-2H-pyrido[1,2- a]pyrazin-1(6H)-one
Show/Hide
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C24H24Cl2FN5O3
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1
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| 1 |
IC50 < 50 nM
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CP0380386
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(3S,8aR)-3-({[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydropyrrolo[1,2- a]pyrazin-1(2H)-one
Show/Hide
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C23H22Cl2FN5O3
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1
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| 1 |
IC50 < 50 nM
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CP0380388
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1,1-dimethylethyl 4-[3-({[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-1,2,4- oxadiazol-5-yl]piperidine-1-carboxylate
Show/Hide
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C28H30Cl2N6O5
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1
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| 1 |
IC50 = 50 nM
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CP0380390
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2-(2-{[4-[(3,4-dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}ethyl)-1H- isoindole-1,3(2H)-dione
Show/Hide
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C25H18Cl2N4O4
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1
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| 1 |
IC50 = 50 nM
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CP0380391
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US9796704, Entry 216
Show/Hide
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C22H21Cl2N7O3
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1
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| 1 |
IC50 < 50 nM
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CP0380395
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N-(3,4-dichlorophenyl)-7-{[(4-ethyl-1,4- oxazepan-2-yl)methyl]oxy}-6- (methyloxy)quinazolin-4-amine
Show/Hide
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C23H26Cl2N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0395755
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2- piperidin-4-yl-1,3-thiazol-4- yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C24H23Cl2N5O2S
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1
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| 1 |
IC50 = 50 nM
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CP0395757
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7-({[4-(cyclopropylmethyl)-1,4-oxazepan-2- yl]methyl}oxy)-N-(3,4-dichlorophenyl)-6- (methyloxy)quinazolin-4-amine
Show/Hide
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C25H28Cl2N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0415980
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N-(3,4-dichlorophenyl)-7-{[(3S,8aR)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
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C23H24Cl2N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0445459
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N-(3-chloro-2,4-difluorophenyl)-7-{[(3S,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
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C23H23ClF2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0445469
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N-(3,4-dichlorophenyl)-7-({[2-(1- ethylpiperidin-3-yl)-1,3-thiazol-4- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine
Show/Hide
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C26H27Cl2N5O2S
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1
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| 1 |
IC50 = 50 nM
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CP0452080
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N-(4-bromo-2,3-dichlorophenyl)-7-{[(3S,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
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C23H23BrCl2N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0452081
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N-(3,4-dichlorophenyl)-7-({[2-(1- ethylpiperidin-4-yl)-1,3-thiazol-4- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine
Show/Hide
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C26H27Cl2N5O2S
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1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0458249
|
N-(3,4-dichlorophenyl)-7-[(hexahydro-1H- [1,4]oxazino[3,4-c][1,4]oxazin-3- ylmethyl)oxy]-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C23H24Cl2N4O4
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0461660
|
(3S,8aS)-3-({[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydropyrrolo[1,2- a]pyrazin-1(2H)-one
Show/Hide
|
C23H22Cl2FN5O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0466803
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5- pyrrolidin-2-yl-1,2,4-oxadiazol-3- yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C22H20Cl2N6O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0466804
|
US9796704, Entry 273
Show/Hide
|
C25H28Cl2N4O5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0467054
|
N-(3,4-dichlorophenyl)-7-({[2-(4- ethylpiperazin-1-yl)-1,3-thiazol-4- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C25H26Cl2N6O2S
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0468537
|
1,4:3,6-dianhydro-5-deoxy-5-({[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-2-O- methyl-D-glucitol
Show/Hide
|
C23H23Cl2N3O5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0473225
|
N-(3,4-dichlorophenyl)-7-{[(4-hex-5-en-1- ylmorpholin-2-yl)methyl]oxy}-6- (methyloxy)quinazolin-4-amine
Show/Hide
|
C26H30Cl2N4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0473228
|
N-(3,4-dichlorophenyl)-7-{[(3R,8aR)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C23H24Cl2N4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0487676
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2- piperidin-3-yl-1,3-thiazol-4- yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C24H23Cl2N5O2S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0487677
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4- propyl-1,4-oxazepan-2- yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C24H28Cl2N4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0487691
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[2- (1-methylpiperidin-4-yl)-1,3-thiazol-4- yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C25H25Cl2N5O2S
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0487692
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2- piperidin-2-yl-1,3-thiazol-4- yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C24H23Cl2N5O2S
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0487699
|
1,4:3,6-dianhydro-5-({[4-[(4-bromo-2,3- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-5- deoxy-2-O-methyl-D-glucitol
Show/Hide
|
C23H22BrCl2N3O5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0487702
|
N-(3,4-dichlorophenyl)-7-({[5-(1- ethylpiperidin-2-yl)-1,2,4-oxadiazol-3- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C25H26Cl2N6O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0487718
|
N-(3,4-dichlorophenyl)-7-{[(3aR,6aS)-2- methyloctahydrocyclopenta[c]pyrrol-5- yl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C23H24Cl2N4O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0487720
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[(1,3- thiazol-4-ylmethyl)oxy]quinazolin-4-amine
Show/Hide
|
C19H14Cl2N4O2S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0487721
|
7-[(cyclopropylmethyl)oxy]-N-(3,4- dichlorophenyl)-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C19H17Cl2N3O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0487722
|
US9796704, Entry 194
Show/Hide
|
C22H23Cl2N3O7
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0487724
|
N-(3,4-dichlorophenyl)-7-({[2-(1- ethylpiperidin-2-yl)-1,3-thiazol-4- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C26H27Cl2N5O2S
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0493314
|
N-(3,4-dichlorophenyl)-7-({[5-(1- ethylpiperidin-4-yl)-1,2,4-oxadiazol-3- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C25H26Cl2N6O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0493322
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7- [(4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin- 2-ylmethyl)oxy]quinazolin-4-amine
Show/Hide
|
C22H19Cl2N5O2S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0507993
|
N-(4,5-dichloro-2-fluorophenyl)-7-{[(3S,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C23H23Cl2FN4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0508004
|
N-(3,4-dichloro-2-fluorophenyl)-7-{[(3S,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C23H23Cl2FN4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0508005
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7- [(tetrahydrofuran-2-ylmethyl)oxy]quinazolin- 4-amine
Show/Hide
|
C20H19Cl2N3O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0508008
|
N-(3,4-dichlorophenyl)-7-({[5-(1- ethylpiperidin-3-yl)-1,2,4-oxadiazol-3- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C25H26Cl2N6O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0509854
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[3- (4-methylpiperazin-1-yl)-1,2,4-oxadiazol-5- yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C23H23Cl2N7O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0509900
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[(2- pyrrolidin-1-ylethyl)oxy]quinazolin-4-amine
Show/Hide
|
C21H22Cl2N4O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0509901
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({4- [(4-methylpiperazin-1-yl)methyl]-1,3-thiazol- 2-yl}methyl)oxy]quinazolin-4-amine
Show/Hide
|
C25H26Cl2N6O2S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0513288
|
N-(4-bromo-3-chloro-2-fluorophenyl)-7- {[(3S,8aS)-hexahydro-1H-pyrrolo[2,1- c][1,4]oxazin-3-ylmethyl]oxy}-6- (methyloxy)quinazolin-4-amine
Show/Hide
|
C23H23BrClFN4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0515482
|
N-(3,4-dichlorophenyl)-7-{[(3R,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C23H24Cl2N4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0515483
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7- [(pyridin-3-ylmethyl)oxy]quinazolin-4-amine
Show/Hide
|
C21H16Cl2N4O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0515550
|
N-(3,4-dichlorophenyl)-7-({[5-(1- ethylpyrrolidin-2-yl)-1,2,4-oxadiazol-3- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C24H24Cl2N6O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0517548
|
1,4:3,6-dianhydro-5-deoxy-5-({[4-[(4,5- dichloro-2-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-2-O- methyl-D-glucitol
Show/Hide
|
C23H22Cl2FN3O5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0517549
|
(3S,8aS)-3-({[4-[(4-bromo-3-chloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydropyrrolo[1,2- a]pyrazin-1(2H)-one
Show/Hide
|
C23H22BrClFN5O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0519375
|
N-(3,4-dichlorophenyl)-7-({[4-(1- methylethyl)morpholin-2-yl]methyl}oxy)-6- (methyloxy)quinazolin-4-amine
Show/Hide
|
C23H26Cl2N4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0525431
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[2- (1-methylpyrrolidin-2-yl)ethyl]oxy}quinazolin- 4-amine
Show/Hide
|
C22H24Cl2N4O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0525444
|
N-(3,4-dichlorophenyl)-7-({[4-(1-methylethyl)- 1,4-oxazepan-2-yl]methyl}oxy)-6- (methyloxy)quinazolin-4-amine
Show/Hide
|
C24H28Cl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0529534
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7- {[(8aR)-tetrahydro-1H-[1,3]thiazolo[4,3- c][1,4]oxazin-6-ylmethyl]oxy}quinazolin-4- amine
Show/Hide
|
C22H22Cl2N4O3S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0530866
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({2- [(2S)-1-methylpyrrolidin-2-yl]-1,3-thiazol-4- yl}methyl)oxy]quinazolin-4-amine
Show/Hide
|
C24H23Cl2N5O2S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0530868
|
6-[2-({[4-[(3,4-dichlorophenyl)amino]-6- (methyloxy)quinazolin-7- yl]oxy}methyl)morpholin-4-yl]hexanenitrile
Show/Hide
|
C26H29Cl2N5O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0534846
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2- piperazin-1-yl-1,3-thiazol-4- yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C23H22Cl2N6O2S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0534847
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({4- [2-(methyloxy)ethyl]morpholin-2- yl}methyl)oxy]quinazolin-4-amine
Show/Hide
|
C23H26Cl2N4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0534848
|
2-({2-[2-({[4-[(3,4-dichlorophenyl)amino]-6- (methyloxy)quinazolin-7- yl]oxy}methyl)morpholin-4- yl]ethyl}oxy)ethanol
Show/Hide
|
C24H28Cl2N4O5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0539875
|
N-(3,4-dichlorophenyl)-7-{[(3S,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C23H24Cl2N4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0545593
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4- (morpholin-4-ylmethyl)-1,3-thiazol-2- yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C24H23Cl2N5O3S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0545604
|
(3S,9aR)-3-({[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydro-2H-pyrido[1,2- a]pyrazin-1(6H)-one
Show/Hide
|
C24H24Cl2FN5O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0551124
|
N-(3,4-dichlorophenyl)-7-{[(4-ethylmorpholin- 2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C22H24Cl2N4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0551137
|
US9796704, Entry 246
Show/Hide
|
C20H16Cl2N4O3S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0551138
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({4- [2-(methyloxy)ethyl]-1,4-oxazepan-2- yl}methyl)oxy]quinazolin-4-amine
Show/Hide
|
C24H28Cl2N4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0555740
|
N-(3,4-dichlorophenyl)-7-{[2-(1,3-dioxolan-2- yl)ethyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C20H19Cl2N3O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0555741
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[2- (1-methylpiperidin-2-yl)-1,3-thiazol-4- yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C25H25Cl2N5O2S
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0563760
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[(2- piperidin-1-ylethyl)oxy]quinazolin-4-amine
Show/Hide
|
C22H24Cl2N4O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0565355
|
US9796704, Entry 276
Show/Hide
|
C24H26Cl2N4O5
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0566218
|
N-(3,4-dichlorophenyl)-7-[({4-[(4-methyl-1,4- diazepan-1-yl)methyl]-1,3-thiazol-2- yl}methyl)oxy]-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C26H28Cl2N6O2S
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0566531
|
N-(3,4-dichlorophenyl)-7-({[3-(4- ethylpiperazin-1-yl)-1,2,4-oxadiazol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C24H25Cl2N7O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0567339
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4- (3-phenylpropyl)morpholin-2- yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C29H30Cl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0572010
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({3- [(2S)-1-methylpyrrolidin-2-yl]-1,2,4-oxadiazol- 5-yl}methyl)oxy]quinazolin-4-amine
Show/Hide
|
C23H22Cl2N6O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0572011
|
7-{[(4-cyclopentylmorpholin-2-yl)methyl]oxy}- N-(3,4-dichlorophenyl)-6- (methyloxy)quinazolin-4-amine
Show/Hide
|
C25H28Cl2N4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0574723
|
N-(3,4-dichlorophenyl)-7-{[2-(1,3-dioxan-2- yl)ethyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C21H21Cl2N3O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0574724
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[(2- morpholin-4-ylethyl)oxy]quinazolin-4-amine
Show/Hide
|
C21H22Cl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0574726
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({2- [(4S)-1,3-thiazolidin-4-yl]-1,3-thiazol-4- yl}methyl)oxy]quinazolin-4-amine
Show/Hide
|
C22H19Cl2N5O2S2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0848456
|
(3S,8aS)-3-({[4-[(3,4-dichloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-2-methylhexahydropyrrolo[1,2-a]pyrazin-1(2H)-one
Show/Hide
|
C24H24Cl2FN5O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0848462
|
N-(3,4-dichlorophenyl)-7-[({2-[(2S)-1-ethylpyrrolidin-2-yl]-1,3-thiazol-4-yl}methyl)oxy]-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C25H25Cl2N5O2S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0856508
|
N-(4-bromo-2,3-dichlorophenyl)-7-{[(3R,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C24H25BrCl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0856512
|
N-(3,4-dichlorophenyl)-6-[(1-methylethyl)oxy]-7-[(morpholin-2-ylmethyl)oxy]quinazolin-4-amine
Show/Hide
|
C22H24Cl2N4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0856517
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[2-(1-methylpiperidin-3-yl)-1,3-thiazol-4-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C25H25Cl2N5O2S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0867264
|
N-(3-chloro-4-fluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C21H22ClFN4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0867265
|
N-(3-bromo-2-methylphenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C22H25BrN4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0867266
|
N'-cyano-2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)morpholine-4-carboximidamide
Show/Hide
|
C22H21Cl2N7O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0867267
|
N-(3,4-dichlorophenyl)-7-({[4-(2-ethylbutyl)morpholin-2-yl]methyl}oxy)-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C26H32Cl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0867268
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4-(2-phenylbutanoyl)morpholin-2-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
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C30H30Cl2N4O4
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1
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| 1 |
IC50 = 50 nM
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CP0869466
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4-pentylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C25H30Cl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0869467
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2-[2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)morpholin-4-yl]acetamide
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C22H23Cl2N5O4
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1
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| 1 |
IC50 = 50 nM
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CP0869468
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N-(3,4-dichlorophenyl)-7-[({4-[(2,5-difluorophenyl)carbonyl]morpholin-2-yl}methyl)oxy]-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C27H22Cl2F2N4O4
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1
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| 1 |
IC50 = 50 nM
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CP0869469
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N-(3,4-dichlorophenyl)-7-({[4-(2-ethylhexanoyl)morpholin-2-yl]methyl}oxy)-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C28H34Cl2N4O4
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1
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| 1 |
IC50 = 50 nM
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CP0869470
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7-({[4-(1,3-benzodioxol-5-ylcarbonyl)morpholin-2-yl]methyl}oxy)-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C28H24Cl2N4O6
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1
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| 1 |
IC50 = 50 nM
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CP0869471
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N-(3,4-dichlorophenyl)-6-(ethyloxy)-7-[(morpholin-2-ylmethyl)oxy]quinazolin-4-amine
Show/Hide
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C21H22Cl2N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0869472
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N-(4-bromo-2-methylphenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C22H25BrN4O3
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1
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| 1 |
IC50 = 50 nM
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CP0869473
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N-(4-chloro-3-methylphenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C22H25ClN4O3
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1
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| 1 |
IC50 = 50 nM
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CP0869474
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[(1E)-[2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)morpholin-4-yl](piperidin-1-yl)methylidene]cyanamide
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C27H29Cl2N7O3
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1
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| 1 |
IC50 = 50 nM
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CP0869475
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N-(3,4-dichlorophenyl)-7-{[(6,6-dimethylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C22H24Cl2N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0869476
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4,6,6-trimethylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C23H26Cl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0869478
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1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-2-(diethylamino)-L-iditol
Show/Hide
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C25H28BrClN4O4
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1
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| 1 |
IC50 = 50 nM
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CP0869483
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N-(3-chloro-2,4-difluorophenyl)-7-{[(3S,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H23ClF2N4O4
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1
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| 1 |
IC50 = 50 nM
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CP0869484
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N-(4,5-dichloro-2-fluorophenyl)-7-{[(3S,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H23Cl2FN4O4
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1
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| 1 |
IC50 = 50 nM
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CP0869504
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4-(tetrahydro-2H-pyran-2-ylmethyl)morpholin-2-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
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C26H26Cl2N4O4
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1
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| 1 |
IC50 < 50 nM
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CP0869543
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N-(2,4-dibromophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]6-(methyloxy)quinazolin-4-amine
Show/Hide
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C21H22Br2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0870272
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3-[2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)morpholin-4-yl]-3-oxopropanoic acid
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C23H22Cl2N4O6
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1
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| 1 |
IC50 < 50 nM
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CP0884372
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N-(4-bromo-3-chloro-2-fluorophenyl)-7-{[(3S,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H23BrClFN4O4
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1
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| 1 |
IC50 < 50 nM
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CP0884377
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1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3-chloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-y1]-5-O-methyl-L-iditol
Show/Hide
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C22H20BrClFN3O5
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1
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| 1 |
IC50 = 50 nM
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CP0893936
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2-[2-({[4-[(3,4-dichloropheyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)morpholon-4-yl]-1-phenylethanone
Show/Hide
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C28H24Cl2N4O5
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1
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| 1 |
IC50 = 50 nM
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CP0893937
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N-(3,4-dichlorophenyl)-7-({[4-(ethylsulfonyl)morpholin-2-yl]methyl}oxy)-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C22H24Cl2N4O5S
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1
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| 1 |
IC50 = 50 nM
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CP0893938
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N-(3,4-dichlorophenyl)-7-{[(6-ethyl-4,6-dimethylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C24H28Cl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0893939
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N-(4-bromo-3-chlorophenyl)-6-(methyloxy)-7-[(1-methylpyrrolidin-3-yl)oxy]quinazolin-4-amine
Show/Hide
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C20H20BrClN4O2
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1
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| 1 |
IC50 = 50 nM
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CP0893940
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N-(3,4-dichloro-2-fluorophenyl)-7-{[(3S,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H23Cl2FN4O4
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1
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| 1 |
IC50 < 50 nM
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CP0895616
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
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C24H24Cl2N6O2S
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1
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| 1 |
IC50 = 50 nM
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CP0895618
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N-(2,4-dichlorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]6-(methyloxy)quinazolin-4-amine
Show/Hide
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C21H22Cl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0895621
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N-(3-chloro-2,4-difluorophenyl)-7-{[(3R,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H23ClF2N4O4
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1
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| 1 |
IC50 = 50 nM
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CP0895622
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N-(4-bromo-3-chloro-2-fluorophenyl)-7-{[(3R,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H23BrClFN4O4
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1
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| 1 |
IC50 < 50 nM
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CP0897772
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4-pent-2-yn-1-ylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C25H26Cl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0899519
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4-oct-7-en-1-ylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C28H34Cl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0899520
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6-[2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-4-yl]oxy}methyl)morpholin-4-yl]hexan-1-ol
Show/Hide
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C26H32Cl2N4O4
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1
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| 1 |
IC50 < 50 nM
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CP0899521
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7-({[4-(cyclopropylmethyl)morpholin-2-yl]methyl}oxy)-N-(dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C24H26Cl2N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0899522
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4-prop-2-yn-1-ylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C23H22Cl2N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0899523
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N-(3-chloro-2-methylphenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C22H25ClN4O3
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1
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| 1 |
IC50 = 50 nM
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CP0899524
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N-(5-chloro-2-fluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C21H22ClFN4O3
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1
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| 1 |
IC50 = 50 nM
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CP0899525
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3-[2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)morpholin-4-yl]butan-2-one
Show/Hide
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C24H26Cl2N4O4
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1
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| 1 |
IC50 = 50 nM
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CP0899591
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{[(4-butylmorpholin-2-yl)methyl]oxy}-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C24H28Cl2N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0899592
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4-({[4-[(4-bromo-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-N'-cyanopiperidine-1-carboximidaimde
Show/Hide
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C23H23BrFN7O2
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1
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| 1 |
IC50 < 50 nM
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CP0899593
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4-(methylsulfonyl)morpholin-2-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
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C21H22Cl2N4O5S
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1
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| 1 |
IC50 = 50 nM
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CP0899594
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N-(3,4-dichlorophenyl)-7-{[(4-hexanoylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C26H30Cl2N4O4
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1
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| 1 |
IC50 = 50 nM
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CP0900963
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4-(tetrahydro-2H-pyran-4-yl)morpholin-2-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
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C25H28Cl2N4O4
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1
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| 1 |
IC50 = 50 nM
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CP0900964
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4-{[3-(methyloxy)phenyl]acetyl}morpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C29H28Cl2N4O5
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1
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| 1 |
IC50 = 50 nM
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CP0900965
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N-(4-bromo-3-methylphenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C22H25BrN4O3
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1
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| 1 |
IC50 = 50 nM
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CP0900966
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N-(3-chloro-2,4-difluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C21H21ClF2N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0901757
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N-(3,4-dichloro-2-methylphenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C22H24Cl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0902686
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4-[(3,4-dichlorophenyl)amino]-7-{[(4-methylmorpholin-2-yl)methyl]oxy}quinazolin-6-ol
Show/Hide
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C20H20Cl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0902687
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N'-cyano-2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-N-ethylmorpholine-4-carboximidamide
Show/Hide
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C24H25Cl2N7O3
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1
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| 1 |
IC50 = 50 nM
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CP0902688
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N-(2,3-dichloro-4-methylphenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C22H24Cl2N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0903644
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[2-(pyrrolidin-1-ylmethyl)-1,3-thiazol-4-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
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C24H23Cl2N5O2S
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1
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| 1 |
IC50 = 50 nM
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CP0903645
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7-({[4-(cyclohexylmethy)morpholin-2-yl]methyl}oxy)-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C27H32Cl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0903646
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N-(3,4-dichlorophenyl)-7-[({4-[2-(1,3-dioxolan-2-yl)ethyl]morpholin-2-yl}methyl)oxy]-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C25H28Cl2N4O5
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1
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| 1 |
IC50 = 50 nM
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CP0903647
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[2-(4,5,5-trimethylmorpholin-2-yl)ethyl]oxy}quinazolin-4-amine
Show/Hide
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C24H28Cl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0903650
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N-(3,4-dichloro-2-fluorophenyl)-6-(methyloxy)-7-{[(4,5,5-trimethylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C23H25Cl2FN4O3
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1
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| 1 |
IC50 < 50 nM
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CP0912090
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N-(3,4-dichlorophenyl)-7-{[(5-ethyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C24H25Cl2N5O2S
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1
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| 1 |
IC50 = 50 nM
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CP0912091
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N-(4-bromo-2,3-dichlorophenyl)-6-(methyloxy)-7-{[(4,5,5-trimethylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C23H25BrCl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0912092
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(6S)-6-({[4-[(3,4-dichloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-1,4-dimethylpiperazin-2-one
Show/Hide
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C22H22Cl2FN5O3
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1
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| 1 |
IC50 = 50 nM
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CP0920903
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7-[({4-[(3-chloropropyl)sulfonyl]morpholin-2-yl}methyl)oxy]-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H25Cl3N4O5S
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1
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| 1 |
IC50 = 50 nM
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CP0920904
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4-propanoylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C23H24Cl2N4O4
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1
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| 1 |
IC50 = 50 nM
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CP0920905
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4,5,5-trimethylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C23H26Cl2N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0920906
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N-(4-bromo-2,5-difluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C21H21BrF2N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0920907
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N-(3,4-dichloro-2-fluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C21H21Cl2FN4O3
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1
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| 1 |
IC50 < 50 nM
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CP0920909
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N-(4,5-dichloro-2-fluorophenyl)-7-{[(3R,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H23Cl2FN4O4
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1
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| 1 |
IC50 = 50 nM
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CP0920910
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N-(4-bromo-5-chloro-2-fluorophenyl)-7-{[(3S,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H23BrClFN4O4
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1
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| 1 |
IC50 = 50 nM
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CP0920942
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5-{[(phenylmethyl)oxy]methyl}-1,2,4-oxadiazol-3-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C26H21Cl2N5O4
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1
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| 1 |
IC50 = 50 nM
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CP0921729
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({3-[(pyridin-2-ylsulfonyl)methyl]-1,2,4-oxadiazol-5-yl}methyl)oxy]quinazolin-4-amine
Show/Hide
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C24H18Cl2N6O5S
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1
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| 1 |
IC50 = 50 nM
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CP0921766
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N-(3,4-dichloro-2-fluorophenyl)-7-{[(3R,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H23Cl2FN4O4
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1
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| 1 |
IC50 < 50 nM
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CP0923157
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N'-cyano-2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-1,4-oxazepane-4-carboximidamide
Show/Hide
|
C23H23ClFN7O3
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1
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| 1 |
IC50 = 50 nM
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CP0923158
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N-(3,4-dichlorophenyl)-7-[({4-[(4-(fluorophenyl)sulfonyl]morpholin-2-yl}methyl)oxy]-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C26H23Cl2FN4O5S
|
1
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| 1 |
IC50 = 50 nM
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CP0923166
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2-[2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)morpholin-4-yl]ethanol
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C22H24Cl2N4O4
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1
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| 1 |
IC50 = 50 nM
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CP0923167
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N-(3,4-dichlorophenyl)--7-({[4-(3-methylbutyl)-1,4-oxazepan-2-yl]methyl}oxy)-6-(methyloxy)quinazolin-4-amine
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C26H32Cl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0923942
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7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)-N-(3,4,5-trichlorophenyl)quinazolin-4-amine
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C21H21Cl3N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0923943
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N-(3,4-dichlorophenyl)-7-[({4-[(3,5-dimethylisoxazol-4-yl)carbonyl]morpholin-2-yl}methyl)oxy]-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C26H25Cl2N5O5
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1
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| 1 |
IC50 = 50 nM
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CP0923944
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N-(3,4-dichlorophenyl)-7-{[2-(5,5-dimethylmorpholin-2-yl)ethyl]oxy}-6-(methyloxy)quinazolin-4-amine
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C23H26Cl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0923945
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[2-(4,6,6-trimethylmorpholin-2-yl)ethyl]oxy}quinazolin-4-amine
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C24H28Cl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0923946
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N-(4-bromo-5-chloro-2-fluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
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C21H21BrClFN4O3
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1
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| 1 |
IC50 < 50 nM
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CP0923947
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(6S)-6-({[4-[(3,4-dichloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-4-methylpiperazin-2-one
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C21H20Cl2FN5O3
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1
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| 1 |
IC50 = 50 nM
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CP0924118
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N-(3,4-dichlorophenyl)-7-({[4-[4-fluorobutyl]morpholin-2-yl}methyl)oxy]-6-(methyloxy)quinazolin-4-amine
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C24H27Cl2FN4O3
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1
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| 1 |
IC50 < 50 nM
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CP0924119
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7-[({4-[(2E)-3-bromoprop-2-en-1-yl]morpholin-2-yl}methyl)oxy]-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H23BrCl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0924120
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7-[({4-[(2-chloropyridin-3-yl)carbonyl]morpholin-2-yl}methyl)oxy]-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
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C26H22Cl3N5O4
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1
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| 1 |
IC50 < 50 nM
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CP0924121
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N-(3,4-dichlorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-{[2-(methyloxy)ethyl]oxy}quinazolin-4-amine
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C23H26Cl2N4O4
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1
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| 1 |
IC50 = 50 nM
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CP0924122
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N-(3-bromo-4-chlorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
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C21H22BrClN4O3
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1
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| 1 |
IC50 = 50 nM
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CP0924123
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[(1E)-[2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)morpholin-4-yl](pyrrolidin-1-yl)methylidene]cyanamide
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C26H27Cl2N7O3
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1
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| 1 |
IC50 = 50 nM
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CP0924133
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N'-cyano-2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-N-methylmorpholine-4-carboximidamide
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C24H26ClN7O3
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1
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| 1 |
IC50 = 50 nM
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CP0924134
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N-(4-bromo-2,3-difluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
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C21H21BrF2N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0924135
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(6S)-6-({[4-[(4-bromo-3-chloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-4-methylpiperazin-2-one
Show/Hide
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C21H20BrClFN5O3
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1
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| 1 |
IC50 = 50 nM
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CP0926169
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N-(4-bromo-3-chlorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
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C21H22BrClN4O3
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1
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| 1 |
IC50 < 50 nM
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CP0926505
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[5-(1-methylpyrrolidin-2-yl)-1,2,4-oxadiazol-3-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
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C23H22Cl2N6O3
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1
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| 1 |
IC50 = 50 nM
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CP0926506
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7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)-N-(2,3,4-trichlorophenyl)quinazolin-4-amine
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C21H21Cl3N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0928848
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N-(3-bromo-4-methylphenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
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C22H25BrN4O3
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1
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| 1 |
IC50 < 50 nM
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CP0928849
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7-{[(4-acetyl-1,4-oxazepan-2-yl)methyl]oxy}-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
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C23H24Cl2N4O4
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1
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| 1 |
IC50 = 50 nM
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CP0930214
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N-(4-bromo-5-chloro-2-fluorophenyl)-7-{[(3R,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H23BrClFN4O4
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1
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| 1 |
IC50 = 50 nM
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CP0930302
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N-(3,4-dichlorophenyl)-7-({[4-(furan-3-ylcarbonyl)morpholin-2-yl]methyl}oxy)-6-(methyloxy)quinazolin-4-amine
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C25H22Cl2N4O5
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1
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| 1 |
IC50 = 50 nM
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CP0930303
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N'-cyano-2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-N-[2-(methyloxy)ethyl]morpholine-4-carboximidamide
Show/Hide
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C25H27Cl2N7O4
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1
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| 1 |
IC50 = 50 nM
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CP0930304
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[(1E)-[2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)morpholin-4-yl](4-methylpiperazin-1-yl)methylidene]cyanamide
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C27H30Cl2N8O3
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1
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| 1 |
IC50 < 50 nM
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CP0930305
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N-(4-bromo-3-chloro-2-methylphenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C22H24BrClN4O3
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1
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| 1 |
IC50 = 50 nM
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CP0930306
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N-(4-bromo-5-chloro-2-fluorophenyl)-6-(methyloxy)-7-{[(4,5,5-trimethylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C23H25BrClFN4O3
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1
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| 1 |
IC50 < 50 nM
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CP0930307
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N-(4,5-dichloro-2-fluorophenyl)-6-(methyloxy)-7-{[(4,5,5-trimethylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C23H25Cl2FN4O3
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1
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| 1 |
IC50 < 50 nM
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CP0930316
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methyl 5-[2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)morpholin-4-yl]pentanoate
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C26H30Cl2N4O5
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1
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| 1 |
IC50 = 50 nM
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CP0930317
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N-(3-chloro-2-fluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C21H22ClFN4O3
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1
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| 1 |
IC50 = 50 nM
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CP0938039
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7-({[4-(cyclopentylcarbonyl)morpholin-2-yl]methyl}oxy)-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C26H28Cl2N4O4
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1
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| 1 |
IC50 = 50 nM
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CP0938053
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N-(4-bromo-3-chlorophenyl)-6-(methyloxy)-7-[(3R)-tetrahydrofuran-3-yloxy]quinazolin-4-amine
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C19H17BrClN3O3
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1
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| 1 |
IC50 = 50 nM
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CP0942317
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N-(4,5-dichloro-2-fluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C21H21Cl2FN4O3
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1
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| 1 |
IC50 = 50 nM
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CP0942462
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1,4:3,6-dianhydro-5-O-[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-O-methyl-D-xylo-hexitol
Show/Hide
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C22H21Cl2N3O5
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1
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| 1 |
IC50 = 50 nM
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CP0942584
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N-(4-bromo-2,3-dichlorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C21H21BrCl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0942612
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N-(3,4-dichlorophenyl)-7-[({4-[(4-fluorophenyl)methyl]morpholin-2-yl}methyl)oxy]-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C27H25Cl2FN4O3
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1
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| 1 |
IC50 = 50 nM
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CP0942613
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4-(pyridin-2-ylmethyl)morpholin-2-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
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C26H25Cl2N5O3
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1
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| 1 |
IC50 < 50 nM
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CP0942615
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N-(3,4-dichlorophenyl)-7-{[(4-ethanimidoyl-1,4-oxazepan-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H25Cl2N5O3
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1
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| 1 |
IC50 < 50 nM
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CP0942616
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N-(3,4-dichlorophenyl)-7-[({4-[(2R)-2-methylbutyl]morpholin-2-yl}methyl)oxy)-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C25H30Cl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0942618
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7-({[4-(2-cyclohexylethyl)-1,4-oxazepan-2-yl]methyl}oxy)-4-[(3,4-dichlorophenyl)methyl]-6-(methyloxy)quinazoline
Show/Hide
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C29H36Cl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0942620
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7-({[4-(butylsulfonyl)morpholin-2-yl]methyl}oxy)-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C24H28Cl2N4O5S
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1
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| 1 |
IC50 = 50 nM
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CP0944879
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N-(3,4-dichlorophenyl)-7-[({3-[(2S)-1-ethylpyrrolidin-2-yl]-1,2,4-oxadiazol-5-yl}methyl)oxy]-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C24H24Cl2N6O3
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1
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| 1 |
IC50 = 50 nM
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CP0944880
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N-(3,4-dichlorophenyl)-6-[(1-methylethyl)oxy]-7-{[(4-methylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C23H26Cl2N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0947311
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C23H21Cl2N5O2S
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1
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| 1 |
IC50 = 50 nM
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CP0947313
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N-(3-chloro-2,4-difluorophenyl)-6-(methyloxy)-7-{[(4,5,5-trimethylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C23H25ClF2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0947314
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N-(4-bromo-2,3-dichlorophenyl)-7-{[(3S,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H23BrCl2N4O4
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1
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| 1 |
IC50 = 50 nM
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CP0947345
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({3-[(2S)-pyrrolidin-2-yl]-1,2,4-oxadiazol-5-yl}methyl)oxy]quinazolin-4-amine
Show/Hide
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C22H20Cl2N6O3
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1
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| 1 |
IC50 = 50 nM
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CP0952649
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(6S)-6-({[4-[(4-bromo-3-chloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-1,4-dimethylpiperazin-2-one
Show/Hide
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C22H22BrClFN5O3
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1
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| 1 |
IC50 = 50 nM
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CP0952653
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N-(4-bromo-5-chloro-2-fluorophenyl)-7-{[(3S,8aS)-hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H23BrClFN4O3
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1
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| 1 |
IC50 < 50 nM
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CP0954969
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N-(3,4-dichlorophenyl)-6-(ethyloxy)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C22H24Cl2N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0954970
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N-(4-bromo-3-chloro-2-fluorophenyl)-6-(methyloxy)-7-{[(4,5,5-trimethylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C23H25BrClFN4O3
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1
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| 1 |
IC50 < 50 nM
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CP0957517
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({4-[(2,3,6-trifluorophenyl)carbonyl]morpholin-2-yl}methyl)oxy]quinazolin-4-amine
Show/Hide
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C27H21Cl2F3N4O4
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1
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| 1 |
IC50 = 50 nM
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CP0957519
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N-(4-bromo-2-chlorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C21H22BrClN4O3
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1
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| 1 |
IC50 = 50 nM
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CP0958991
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4-(methylsulfonyl)-1,4-oxazepan-2-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
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C22H24Cl2N4O5S
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1
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| 1 |
IC50 = 50 nM
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CP0959854
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7-{[(4-but-2-yn-1-ylmorpholin-2-yl)methyl]oxy}-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C24H24Cl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0959855
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7-({[4-(2-cyclohexylethyl)morpholin-2-yl]methyl}oxy)-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C28H34Cl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0959856
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7-({[4-(cyclohexylmethyl)-1,4-oxazepan-2-yl]methyl}oxy)-4-[(3,4-dichlorophenyl)methyl]-6-(methyloxy)quinazoline
Show/Hide
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C28H34Cl2N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0959857
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4-(phenylsulfonyl)morpholin-2-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
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C26H24Cl2N4O5S
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1
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| 1 |
IC50 = 50 nM
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CP0961009
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7-{[(4-acetylmorpholin-2-yl)methyl]oxy}-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C22H22Cl2N4O4
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1
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| 1 |
IC50 = 50 nM
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CP0961505
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4-propylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C23H26Cl2N4O3
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1
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| 1 |
IC50 = 50 nM
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CP0961506
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N-(4-bromo-3,5-difluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C21H21BrF2N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0961507
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N-(4-bromo-2-fluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C21H22BrFN4O3
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1
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| 1 |
IC50 < 50 nM
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CP0961508
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N-(4-chloro-2-fluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C21H22ClFN4O3
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1
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| 1 |
IC50 < 50 nM
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CP0961509
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4-pent-4-en-1-ylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C25H28Cl2N4O3
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1
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| 1 |
IC50 < 50 nM
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CP0961510
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1-[2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)morpholin-4-yl]butan-2-one
Show/Hide
|
C24H26Cl2N4O4
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1
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| 1 |
IC50 = 50 nM
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CP0961511
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4-(2-phenylethyl)morpholin-2-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
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C28H28Cl2N4O3
|
1
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| 1 |
IC50 = 50 nM
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CP0961512
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4-prop-2-en-1-ylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C23H24Cl2N4O3
|
1
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| 1 |
IC50 = 50 nM
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CP0961513
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({4-[3-(tetrahydro-2H-pyran-2-yloxy)propyl]-1,4-oxazepan-2-yl}methyl)oxy]quinazolin-4-amine
Show/Hide
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C29H36Cl2N4O5
|
1
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| 1 |
IC50 < 50 nM
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CP0961514
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4-(1-methylpiperidin-4yl)morpholin-2-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C26H31Cl2N5O3
|
1
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| 1 |
IC50 < 50 nM
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CP0961515
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N-(3,4-dichloropheny)-6-(methyloxy)-7-({[4-(2-methylpentanoyl)morpholin-2-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C26H30Cl2N4O4
|
1
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| 1 |
IC50 = 50 nM
|
|
|
|
CP0961516
|
N-(3,4-dichlorophenyl)-7-({[4-(2,2-dimethylpropanoyl)morpholin-2-yl]methyl}oxy)-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C25H28Cl2N4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0961517
|
N-(3,4-dichlorophenyl)-6-{[2-(methyloxy)ethyl]oxy}-7-[(morpholin-2-ylmethyl)oxy]quinazolin-4-amine
Show/Hide
|
C22H24Cl2N4O4
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0961559
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4-pyridin-4-ylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C25H23Cl2N5O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0961560
|
7-[({4-[(4-chlorophenyl)acetyl]morpholin-2-yl}methyl)oxy]-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C28H25Cl3N4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0961563
|
N-(3-bromo-2-chlorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C21H22BrClN4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0962705
|
4-[2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)morpholin-4-yl]butanenitrile
Show/Hide
|
C24H25Cl2N5O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0962730
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4-(2-propylpentanoyl)morpholin-2-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C28H34Cl2N4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0962731
|
methyl 4-[2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)morpholin-4-yl]-4-oxobutanoate
Show/Hide
|
C25H26Cl2N4O6
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0963411
|
N-(3,4-dichlorophenyl)-7-{[(4-hexylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C26H32Cl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0963412
|
N-(3,4-dichlorophenyl)-7-{[(4-heptylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C27H34Cl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0963413
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({4-(phenylmethyl)sulfonyl]morpholin-2-yl}methyl)oxy]quinazolin-4-amine
Show/Hide
|
C27H26Cl2N4O5S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0963414
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4-(naphthalen-1-ylcarbonyl)morpholin-2-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C31H26Cl2N4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0963485
|
N-(4-bromo-3-chloro-2-fluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C21H21BrClFN4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0963491
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({2-[(2S)-pyrrolidin-2-yl]-1,3-thiazol-4-yl}methyl)oxy]quinazolin-4-amine
Show/Hide
|
C23H21Cl2N5O2S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0964028
|
7-[({4-[(6-chloropyridin-3-yl)carbonyl]morpholin-2-yl}methyl)oxy]-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C26H22Cl3N5O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0964029
|
6-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-3,3,4-trimethylmorpholin-2-one
Show/Hide
|
C23H24Cl2N4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0964042
|
7-{[(4-cyclobutylmorpholin-2-yl)methyl]oxy}-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C24H26Cl2N4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0964044
|
N-(3,4-dichlorophenyl)-7-({[4-(2-ethylbutyl)-1,4-oxazepan-2-yl]methyl}oxy)-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C27H34Cl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0964046
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({4-[(4-methylphenyl)sulfonyl]morpholin-2-yl}methyl)oxy]quinazolin-4-amine
Show/Hide
|
C27H26Cl2N4O5S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0964047
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4-(4-methylpentanoyl)morpholin-2-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C26H30Cl2N4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0964048
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4-(3-phenylpropanoyl)morpholin-2-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C29H28Cl2N4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0966521
|
N-(3,4-dichlorophenyl)-7-({[4-(2-fluoroethyl)morpholin-2-yl]methyl}oxy)-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C22H23Cl2FN4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0966522
|
N-(3,4-dichlorophenyl)-7-({[4-(3-methylbut-2-en-1-yl)morpholin-2-yl]methyl}oxy)-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C25H28Cl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0420770
|
N-(5-ethylsulfonyl-2-methoxyphenyl)-5-(3-pyridin-2-yl-5-pyridin-3-ylphenyl)-1,3-oxazol-2-amine
Show/Hide
|
C28H24N4O4S
|
1
|
| 1 |
IC50 = 51.2 nM
|
|
|
|
CP0859051
|
N-[4-(2-[6-(4-aminopiperidino)-2-methyl-4-pyrimidinyl]amino-1,3-thiazol-5-yl)phenyl]-N'-phenylurea
Show/Hide
|
C26H28N8OS
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0397402
|
4-(2-morpholin-4-ylethoxy)-N-[5-[4-[(phenylcarbamoylamino)methyl]phenyl]-1H-pyrazol-3-yl]benzamide
Show/Hide
|
C30H32N6O4
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0382325
|
1-(5-butyl-1,2-oxazol-3-yl)-3-[4-[2-[[2-methyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]urea
Show/Hide
|
C27H33N9O2S
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0291574
|
1-N-[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-1-N'-methyl-1-N'-phenylcyclopropane-1,1-dicarboxamide
Show/Hide
|
C29H24FN5O3S
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0373638
|
1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-[3-morpholin-4-yl-5-(trifluoromethyl)-phenyl]urea
Show/Hide
|
C25H22ClF3N6O3
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0664754
|
(Z)-3-({4-[(2-Dimethylamino-acetyl)-methyl-amino]-phenylamino}-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid Methyl Ester
Show/Hide
|
C28H28N4O4
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0507537
|
1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-[4-morpholin-4-yl-3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C25H22ClF3N6O3
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0674917
|
(Z)-3-[(4-Dimethylaminomethyl-phenylamino)-phenyl-methylene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylic Acid Methyl Ester
Show/Hide
|
C26H25N3O3
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0451984
|
N-[5-[3-[(3-methylphenyl)sulfonylamino]phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide
Show/Hide
|
C28H30N6O3S
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0397494
|
N-[5-[4-[[(4-chlorophenyl)carbamoylamino]methyl]phenyl]-1H-pyrazol-3-yl]-4-(2-morpholin-4-ylethoxy)benzamide
Show/Hide
|
C30H31ClN6O4
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0397329
|
4-(4-methylpiperazin-1-yl)-N-[5-[4-(pyridin-2-ylcarbamoylamino)phenyl]-1H-pyrazol-3-yl]benzamide
Show/Hide
|
C27H28N8O2
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0153243
|
4-N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-2-N-[(3-methyl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine
Show/Hide
|
C22H25N7O3
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0566318
|
(2S,4R)-1-[(2S)-2-[[16-[3-amino-4-[4-[(2-fluoro-5-methylphenyl)carbamoylamino]phenyl]indazol-1-yl]-16-oxohexadecanoyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
Show/Hide
|
C59H74FN9O6S
|
1
|
| 1 |
IC50 = 80.42 nM
|
|
|
|
CP0381234
|
4-[(4-methylpiperazin-1-yl)methyl]-N-[5-[4-[(phenylcarbamoylamino)methyl]phenyl]-1H-pyrazol-3-yl]benzamide
Show/Hide
|
C30H33N7O2
|
1
|
| 1 |
IC50 = 82 nM
|
|
|
|
CP0674913
|
(Z)-3-({4-[2-(4-Methylpiperazin-1-yl)acetylamino]-phenylamino}-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acidMethyl Ester
Show/Hide
|
C30H31N5O4
|
1
|
| 1 |
IC50 = 83 nM
|
|
|
|
CP0414697
|
1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[[4-[3-[(2-methyl-6-piperazin-1-ylpyrimidin-4-yl)amino]-1H-pyrazol-5-yl]phenyl]methyl]urea
Show/Hide
|
C27H34N10O2
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0506315
|
(R)-N1-(4-(2-(3-(dimethylamino)pyrrolidine-1-carbonyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-N3-phenylmalonamide
Show/Hide
|
C29H28FN5O4S
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0331772
|
methyl 7-(2-fluoro-4-{[(1-phenylacetamido)methanethioyl]amino}phenoxy)thieno[3,2-b]pyridine-2-carboxylate
Show/Hide
|
C24H18FN3O4S2
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0205639
|
3-(3-fluoro-4-{[2-(pyrimidin-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
|
C26H18FN5O2S2
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
|
CP0539647
|
N-(6-chloro-1,3-benzothiazol-2-yl)-3-(4-fluorophenyl)-1-phenylpyrazole-4-carboxamide
Show/Hide
|
C23H14ClFN4OS
|
1
|
| 1 |
IC50 = 97 nM
|
|
|
|
CP0381232
|
1-[[4-[3-[[2-methyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1H-pyrazol-5-yl]phenyl]methyl]-3-(5-methyl-1,2-oxazol-3-yl)urea
Show/Hide
|
C25H30N10O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0432435
|
N-[5-[4-(ethylcarbamoylamino)phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide
Show/Hide
|
C24H29N7O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0915822
|
(Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenylamino)-methylene]-2,3-dihydro-1H-indole-6-carboxylic Acid Ethyl Ester
Show/Hide
|
C30H31N3O3
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
|
CP0432016
|
3-(4-chlorophenyl)-N-(6-fluoro-1,3-benzothiazol-2-yl)-1-phenylpyrazole-4-carboxamide
Show/Hide
|
C23H14ClFN4OS
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
|
CP0318471
|
3-(3-fluoro-4-{[2-(pyridin-3-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
|
C27H19FN4O2S2
|
1
|
| 1 |
IC50 = 113 nM
|
|
|
|
CP0761920
|
(Z)-3-{[4-(2-Dimethylaminoacetylamino)-phenylamino]-phenylmethylene}-2-oxo-2,3-dihydro-1H-indole-6-carboxylic AcidMethyl Ester
Show/Hide
|
C27H26N4O4
|
1
|
| 1 |
IC50 = 119 nM
|
|
|
|
CP0278627
|
benzyl N-[[4-[3-[[4-(2-pyrrolidin-1-ylethoxy)benzoyl]amino]-1H-pyrazol-5-yl]phenyl]methyl]carbamate
Show/Hide
|
C31H33N5O4
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0490015
|
1-[[4-[3-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1H-pyrazol-5-yl]phenyl]methyl]-3-(5-methyl-1,2-oxazol-3-yl)urea
Show/Hide
|
C26H32N10O3
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0376358
|
benzyl N-[4-[2-[[6-(4-ethylpiperazin-1-yl)-2-methylpyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]carbamate
Show/Hide
|
C28H31N7O2S
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0368765
|
4-[[2-[2-(4-cyanophenyl)-2-oxoethyl]sulfanylpyrimidin-4-yl]amino]benzoic acid
Show/Hide
|
C20H14N4O3S
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0134635
|
2-N-[(3-methyl-1,2-oxazol-5-yl)methyl]-4-N-[5-(2-phenylethyl)-1H-pyrazol-3-yl]pyrimidine-2,4-diamine
Show/Hide
|
C20H21N7O
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0377545
|
4-N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-2-N-[(5-methyl-1,2-oxazol-3-yl)methyl]pyrimidine-2,4-diamine
Show/Hide
|
C22H25N7O3
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0383442
|
5-bromo-4-N-(5-propyl-1H-pyrazol-3-yl)-2-N-(pyridin-3-ylmethyl)pyrimidine-2,4-diamine
Show/Hide
|
C16H18BrN7
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0485402
|
3-(3-fluoro-4-{[2-(furan-2-ylcarbonyl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
|
C27H18FN3O4S2
|
1
|
| 1 |
IC50 = 127 nM
|
|
|
|
CP0858393
|
(Z)-6-Chloro-3-[phenyl-(4-piperidin-1-ylmethyl-phenylamino)-methylene]-indolin-2-one
Show/Hide
|
C27H26ClN3O
|
1
|
| 1 |
IC50 = 129 nM
|
|
|
|
CP0342498
|
7-(2-fluoro-4-{[(1-phenylacetamido)methanethioyl]amino}phenoxy)thieno[3,2-b]pyridine-2-carboxamide
Show/Hide
|
C23H17FN4O3S2
|
1
|
| 1 |
IC50 = 129 nM
|
|
|
|
CP0387627
|
N-[5-[3-(benzenesulfonamido)phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide
Show/Hide
|
C27H28N6O3S
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0397328
|
N-[5-[4-[[(4-fluorophenyl)carbamoylamino]methyl]phenyl]-1H-pyrazol-3-yl]-4-(2-morpholin-4-ylethoxy)benzamide
Show/Hide
|
C30H31FN6O4
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0893260
|
(Z)-6-Amino-3-[phenyl-(4-piperidin-1-ylmethyl-phenylamino)-methylene]-indolin-2-one
Show/Hide
|
C27H28N4O
|
1
|
| 1 |
IC50 = 132 nM
|
|
|
|
CP0554700
|
N-(6-fluoro-1,3-benzothiazol-2-yl)-3-(4-fluorophenyl)-1-phenylpyrazole-4-carboxamide
Show/Hide
|
C23H14F2N4OS
|
1
|
| 1 |
IC50 = 132 nM
|
|
|
|
CP0352912
|
7-(2-fluoro-4-{[(1-phenylacetamido)methanethioyl]amino}phenoxy)-N-methylthieno[3,2-b]pyridine-2-carboxamide
Show/Hide
|
C24H19FN4O3S2
|
1
|
| 1 |
IC50 = 133 nM
|
|
|
|
CP0190764
|
6-[[(1R,2S)-2-aminocyclohexyl]amino]-7-fluoro-4-(1-methylpyrazol-4-yl)-1,2-dihydropyrrolo[3,4-c]pyridin-3-one
Show/Hide
|
C17H21FN6O
|
1
|
| 1 |
IC50 = 135 nM
|
|
|
|
CP0387626
|
N-[3-[3-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1H-pyrazol-5-yl]phenyl]benzenesulfonamide
Show/Hide
|
C26H30N8O3S
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0218990
|
3-(3-fluoro-4-{[2-(1,3,4-thiadiazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
|
C24H16FN5O2S3
|
1
|
| 1 |
IC50 = 145 nM
|
|
|
|
CP0727422
|
(Z)-3-{[4-(N-Methanesulfonyl-methylamino)-phenylamino]-phenylmethylene}-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acidMethylEster
Show/Hide
|
C25H23N3O5S
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0383438
|
5-bromo-2-N-[(3-methyl-1,2-oxazol-5-yl)methyl]-4-N-(5-propyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
Show/Hide
|
C15H18BrN7O
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0459936
|
N-[5-[3-[(4-methoxyphenyl)sulfonylamino]phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide
Show/Hide
|
C28H30N6O4S
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0382169
|
1-[4-[2-[[2-methyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]-3-phenylurea
Show/Hide
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C26H28N8OS
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1
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| 1 |
IC50 = 160 nM
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CP0296610
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N-[3-fluoro-4-[2-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
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C29H26FN5O3S
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1
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| 1 |
IC50 = 170 nM
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CP0442935
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5-(3,5-dipyridin-3-ylphenyl)-N-(5-ethylsulfonyl-2-methoxyphenyl)-1,3-oxazol-2-amine
Show/Hide
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C28H24N4O4S
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1
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| 1 |
IC50 = 170 nM
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CP0449212
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N-[4-[2-[[6-(4-ethylpiperazin-1-yl)-2-methylpyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]benzenesulfonamide
Show/Hide
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C26H29N7O2S2
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1
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| 1 |
IC50 = 170 nM
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CP0168495
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ethyl 4-[[2-[2-(4-cyanophenyl)-2-oxoethyl]sulfanylpyrimidin-4-yl]amino]benzoate
Show/Hide
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C22H18N4O3S
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1
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| 1 |
IC50 = 170 nM
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CP0540825
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4-[[2-[2-(4-chlorophenyl)-2-oxoethyl]sulfanylpyrimidin-4-yl]amino]benzoic acid
Show/Hide
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C19H14ClN3O3S
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1
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| 1 |
IC50 = 170 nM
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CP0253737
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3-(3-fluoro-4-{[2-(pyrimidin-5-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
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C26H18FN5O2S2
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1
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| 1 |
IC50 = 175 nM
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CP0477494
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N-(6-fluoro-1,3-benzothiazol-2-yl)-3-(4-methoxyphenyl)-1-phenylpyrazole-4-carboxamide
Show/Hide
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C24H17FN4O2S
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1
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| 1 |
IC50 = 187 nM
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CP0381231
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4-(4-methylpiperazin-1-yl)-N-[5-[4-(pyridin-3-ylcarbamoylamino)phenyl]-1H-pyrazol-3-yl]benzamide
Show/Hide
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C27H28N8O2
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1
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| 1 |
IC50 = 190 nM
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CP0533597
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ethyl 4-[[2-[2-(4-methoxyphenyl)-2-oxoethyl]sulfanylpyrimidin-4-yl]amino]benzoate
Show/Hide
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C22H21N3O4S
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1
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| 1 |
IC50 = 190 nM
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CP0420465
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5-bromo-2-N-[2-(furan-2-yl)ethyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
Show/Hide
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C14H15BrN6O
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1
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| 1 |
IC50 = 199.53 nM
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CP0529940
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N'-(3-fluoro-4-thieno[3,2-b]pyridin-7-yloxyphenyl)-N-phenylpropanediamide
Show/Hide
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C22H16FN3O3S
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1
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| 1 |
IC50 = 200 nM
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CP0387624
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N-[5-[3-(benzenesulfonamido)phenyl]-1H-pyrazol-3-yl]-4-(2-pyrrolidin-1-ylethoxy)benzamide
Show/Hide
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C28H29N5O4S
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1
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| 1 |
IC50 = 200 nM
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CP0407428
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5-(3-bromo-5-pyridin-2-ylphenyl)-N-(5-ethylsulfonyl-2-methoxyphenyl)-1,3-oxazol-2-amine
Show/Hide
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C23H20BrN3O4S
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1
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| 1 |
IC50 = 202 nM
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CP0572695
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(2S,4R)-1-[(2S)-2-[[12-[3-amino-4-[3-[(3-propan-2-ylphenyl)carbamoylamino]phenyl]indazol-1-yl]-12-oxododecanoyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
Show/Hide
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C57H71N9O6S
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1
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| 1 |
IC50 = 208.15 nM
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CP0566317
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(2S,4R)-1-[(2S)-2-[[12-[3-amino-4-[4-[(2-fluoro-5-methylphenyl)carbamoylamino]phenyl]indazol-1-yl]-12-oxododecanoyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
Show/Hide
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C55H66FN9O6S
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1
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| 1 |
IC50 = 208.66 nM
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CP0107000
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4,4,4-trifluoro-N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-3-(phenylamino)butanamide
Show/Hide
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C27H21F4N5O2S
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1
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| 1 |
IC50 = 210 nM
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CP0415359
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1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-pyridin-2-ylurea
Show/Hide
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C19H15ClN6O2
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1
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| 1 |
IC50 = 210 nM
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CP0492010
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N-(6-chloro-1,3-benzothiazol-2-yl)-3-(4-methoxyphenyl)-1-phenylpyrazole-4-carboxamide
Show/Hide
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C24H17ClN4O2S
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1
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| 1 |
IC50 = 212 nM
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CP0528481
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2-[4-(4-acetylanilino)pyrimidin-2-yl]sulfanyl-1-(4-chlorophenyl)ethanone
Show/Hide
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C20H16ClN3O2S
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1
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| 1 |
IC50 = 220 nM
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CP0191524
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N-[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-3-methyl-2-oxo-1-phenylpyrrolidine-3-carboxamide
Show/Hide
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C29H24FN5O3S
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1
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| 1 |
IC50 = 230 nM
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CP0372738
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1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-pyridin-3-ylurea
Show/Hide
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C19H15ClN6O2
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1
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| 1 |
IC50 = 230 nM
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CP0648235
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(Z)-2-oxo-3-{[4-(2-oxo-Pyrrolidin-1-ylmethyl)-phenylamino]-phenylmethylene}-2,3-dihydro-1H-indole-6-carboxylic Acid Methyl Ester
Show/Hide
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C28H25N3O4
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1
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| 1 |
IC50 = 245 nM
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CP0648236
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(Z)-3-({3-[(3-Dimethylaminopropyl)-methyl-carbamoyl]-phenylamino}-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid Methyl Ester
Show/Hide
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C29H30N4O4
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1
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| 1 |
IC50 = 248 nM
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CP0956577
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(Z)-6-Cyano-3-[phenyl-(4-piperidin-1-ylmethyl-phenylamino)-methylene]-indolin-2-one
Show/Hide
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C28H26N4O
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1
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| 1 |
IC50 = 248 nM
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CP0396774
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N-[5-[3-[(3-chlorophenyl)sulfonylamino]phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide
Show/Hide
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C27H27ClN6O3S
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1
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| 1 |
IC50 = 250 nM
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CP0016677
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N-[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]-N-methylbenzamide
Show/Hide
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C35H30N4O4
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1
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| 1 |
IC50 = 250 nM
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CP0432017
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N-(6-chloro-1,3-benzothiazol-2-yl)-3-(4-chlorophenyl)-1-phenylpyrazole-4-carboxamide
Show/Hide
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C23H14Cl2N4OS
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1
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| 1 |
IC50 = 256 nM
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CP0168494
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1-(4-fluorophenyl)-2-[4-(4-morpholin-4-ylanilino)pyrimidin-2-yl]sulfanylethanone
Show/Hide
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C22H21FN4O2S
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1
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| 1 |
IC50 = 260 nM
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CP0440264
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2-[4-(4-acetylanilino)pyrimidin-2-yl]sulfanyl-1-(4-phenylphenyl)ethanone
Show/Hide
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C26H21N3O2S
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1
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| 1 |
IC50 = 280 nM
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CP0289957
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3-(3-fluoro-4-{[2-(morpholin-4-ylcarbonyl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
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C27H23FN4O4S2
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1
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| 1 |
IC50 = 289 nM
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CP0190889
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N-[3-[3-[[2-methyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1H-pyrazol-5-yl]phenyl]benzenesulfonamide
Show/Hide
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C25H28N8O2S
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1
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| 1 |
IC50 = 290 nM
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CP0911843
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N-Methyl-4-(4-(2-(4-pyridinyl)ethenyl)phenoxy)picolinamide
Show/Hide
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C20H17N3O2
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1
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| 1 |
IC50 = 290 nM
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CP0344987
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1-(4-methoxyphenyl)-2-[4-(4-morpholin-4-ylanilino)pyrimidin-2-yl]sulfanylethanone
Show/Hide
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C23H24N4O3S
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1
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| 1 |
IC50 = 290 nM
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CP0409664
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N-[5-[4-(cyclopropylcarbamoylamino)phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide
Show/Hide
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C25H29N7O2
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1
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| 1 |
IC50 = 300 nM
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CP0657487
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(S,E)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione
Show/Hide
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C19H24O5
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1
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| 1 |
IC50 = 310 nM
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CP0563908
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1-(2,5-dimethylphenyl)-3-[4-(1H-indol-3-ylsulfanyl)-6-piperidin-1-ylpyrimidin-2-yl]urea
Show/Hide
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C26H28N6OS
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1
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| 1 |
IC50 = 310 nM
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CP0563909
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1-(4-chlorophenyl)-3-[4-(1H-indol-3-ylsulfanyl)-6-pyrrolidin-1-ylpyrimidin-2-yl]urea
Show/Hide
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C23H21ClN6OS
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1
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| 1 |
IC50 = 330 nM
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CP0168493
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ethyl 4-[[2-[2-oxo-2-(4-phenylphenyl)ethyl]sulfanylpyrimidin-4-yl]amino]benzoate
Show/Hide
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C27H23N3O3S
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1
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| 1 |
IC50 = 340 nM
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CP0342500
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3-[3-fluoro-4-({2-[(4-methylpiperazin-1-yl)carbonyl]thieno[3,2-b]pyridin-7-yl}oxy)phenyl]-1-(2-phenylacetyl)thiourea
Show/Hide
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C28H26FN5O3S2
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1
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| 1 |
IC50 = 344 nM
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CP0253736
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3-(3-fluoro-4-{[2-(methylsulfanyl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
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C23H18FN3O2S3
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1
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| 1 |
IC50 = 346 nM
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CP0527674
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1-(4-chloro-2-methylphenyl)-3-[4-(1H-indol-3-ylsulfanyl)-6-morpholin-4-ylpyrimidin-2-yl]urea
Show/Hide
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C24H23ClN6O2S
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1
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| 1 |
IC50 = 350 nM
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CP0401944
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3-anilino-N-[4-(6,7-dimethoxyquinolin-4-yl)oxy-3-fluorophenyl]-4,4,4-trifluorobutanamide
Show/Hide
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C27H23F4N3O4
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1
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| 1 |
IC50 = 360 nM
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CP0449211
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N-[5-[4-[(5-methyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-1,3-thiazol-2-yl]-4-(2-morpholin-4-ylethoxy)benzamide
Show/Hide
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C27H28N6O5S
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1
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| 1 |
IC50 = 370 nM
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CP0345798
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N,N-diethyl-7-(2-fluoro-4-{[(1-phenylacetamido)methanethioyl]amino}phenoxy)thieno[3,2-b]pyridine-2-carboxamide
Show/Hide
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C27H25FN4O3S2
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1
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| 1 |
IC50 = 386 nM
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CP0383443
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5-bromo-4-N-(5-propan-2-yl-1H-pyrazol-3-yl)-2-N-(pyridin-3-ylmethyl)pyrimidine-2,4-diamine
Show/Hide
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C16H18BrN7
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1
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| 1 |
IC50 = 398.11 nM
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CP0383496
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4-N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-2-N-(pyridin-2-ylmethyl)pyrimidine-2,4-diamine
Show/Hide
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C23H25N7O2
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1
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| 1 |
IC50 = 398.11 nM
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CP0498427
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N-[5-[3-(benzenesulfonamido)phenyl]-1H-pyrazol-3-yl]-3-(4-methylpiperazin-1-yl)benzamide
Show/Hide
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C27H28N6O3S
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1
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| 1 |
IC50 = 410 nM
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CP0213915
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ethyl 4-[[2-[2-(4-nitrophenyl)-2-oxoethyl]sulfanylpyrimidin-4-yl]amino]benzoate
Show/Hide
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C21H18N4O5S
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1
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| 1 |
IC50 = 410 nM
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CP0365740
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2-[4-(3-acetylanilino)pyrimidin-2-yl]sulfanyl-1-(4-methoxyphenyl)ethanone
Show/Hide
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C21H19N3O3S
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1
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| 1 |
IC50 = 420 nM
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CP0861728
|
QUIZARTINIB DIHYDROCHLORIDE
Show/Hide
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C29H34Cl2N6O4S
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1
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| 1 |
IC50 = 430 nM
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CP0030740
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1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morpholin-4-Yl)ethoxy]imidazo[2,1-B][1,3]benzothiazol-2-Yl}phenyl)urea
Show/Hide
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C29H32N6O4S
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1
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| 1 |
IC50 = 430 nM
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CP0552321
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1-(4-chloro-2-methylphenyl)-3-[4-(1H-indol-3-ylsulfanyl)-6-pyrrolidin-1-ylpyrimidin-2-yl]urea
Show/Hide
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C24H23ClN6OS
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1
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| 1 |
IC50 = 430 nM
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CP0579585
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1-(4-chloro-2-methylphenyl)-3-[4-(cyclopropylamino)-6-(1H-indol-3-ylsulfanyl)pyrimidin-2-yl]urea
Show/Hide
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C23H21ClN6OS
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1
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| 1 |
IC50 = 440 nM
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CP0387628
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N-[5-[3-(benzenesulfonamido)phenyl]-1H-pyrazol-3-yl]-4-morpholin-4-ylbenzamide
Show/Hide
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C26H25N5O4S
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1
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| 1 |
IC50 = 450 nM
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CP0440263
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2-[4-(3-acetylanilino)pyrimidin-2-yl]sulfanyl-1-(4-chlorophenyl)ethanone
Show/Hide
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C20H16ClN3O2S
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1
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| 1 |
IC50 = 480 nM
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CP0564493
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2-[4-(4-acetylanilino)pyrimidin-2-yl]sulfanyl-1-(4-methoxyphenyl)ethanone
Show/Hide
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C21H19N3O3S
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1
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| 1 |
IC50 = 490 nM
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CP0377547
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5-chloro-2-N-[(3-methyl-1,2-oxazol-5-yl)methyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
Show/Hide
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C13H14ClN7O
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1
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| 1 |
IC50 = 501.19 nM
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CP0383441
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5-bromo-2-N-[2-(3-methyl-1,2-oxazol-5-yl)ethyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
Show/Hide
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C14H16BrN7O
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1
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| 1 |
IC50 = 501.19 nM
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CP0433557
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5-bromo-4-N-(5-methyl-1H-pyrazol-3-yl)-2-N-[3-(5-methyl-1H-pyrazol-4-yl)propyl]pyrimidine-2,4-diamine
Show/Hide
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C15H19BrN8
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1
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| 1 |
IC50 = 501.19 nM
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CP0433558
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5-bromo-4-N-(5-ethyl-1H-pyrazol-3-yl)-2-N-(pyridin-2-ylmethyl)pyrimidine-2,4-diamine
Show/Hide
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C15H16BrN7
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1
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| 1 |
IC50 = 501.19 nM
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CP0437837
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5-bromo-4-N-(5-methyl-1H-pyrazol-3-yl)-2-N-[(3-methylpyridin-2-yl)methyl]pyrimidine-2,4-diamine
Show/Hide
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C15H16BrN7
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1
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| 1 |
IC50 = 501.19 nM
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CP0964127
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N-Cyclohexyl-4-(4-(2-(2-pyridinyl)ethenyl)phenoxy)picolinamide
Show/Hide
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C25H25N3O2
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1
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| 1 |
IC50 = 530 nM
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CP0647792
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(S)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione
Show/Hide
|
C19H24O5
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1
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| 1 |
IC50 = 540 nM
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CP0451986
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N-[5-[3-(benzenesulfonamido)phenyl]-1H-pyrazol-3-yl]-4-(morpholin-4-ylmethyl)benzamide
Show/Hide
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C27H27N5O4S
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1
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| 1 |
IC50 = 560 nM
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CP0191526
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3-(3-fluoro-4-{[2-(1-hydroxyethyl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
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C24H20FN3O3S2
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1
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| 1 |
IC50 = 561 nM
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CP0168491
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4-[[2-[2-oxo-2-(4-phenylphenyl)ethyl]sulfanylpyrimidin-4-yl]amino]benzoic acid
Show/Hide
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C25H19N3O3S
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1
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| 1 |
IC50 = 570 nM
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CP0242437
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3-(3-fluoro-4-{[2-(furan-3-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea
Show/Hide
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C26H18FN3O3S2
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1
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| 1 |
IC50 = 593 nM
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CP0458196
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1-[4-[3-[[2-methyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1H-pyrazol-5-yl]phenyl]-3-phenylurea
Show/Hide
|
C26H29N9O
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1
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| 1 |
IC50 = 620 nM
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CP0383497
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5-bromo-4-N-(5-methyl-1H-pyrazol-3-yl)-2-N-(2-pyridin-3-ylethyl)pyrimidine-2,4-diamine
Show/Hide
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C15H16BrN7
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1
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| 1 |
IC50 = 630.96 nM
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CP0423870
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5-bromo-2-N-[(3-methyl-1,2-oxazol-5-yl)methyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
Show/Hide
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C13H14BrN7O
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1
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| 1 |
IC50 = 630.96 nM
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CP0492009
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N-(6-chloro-1,3-benzothiazol-2-yl)-1,3-diphenylpyrazole-4-carboxamide
Show/Hide
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C23H15ClN4OS
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1
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| 1 |
IC50 = 647 nM
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CP0489454
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1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-pyridin-4-ylurea
Show/Hide
|
C19H15ClN6O2
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1
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| 1 |
IC50 = 650 nM
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CP0527675
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1-[4-(4-benzylpiperazin-1-yl)-6-(1H-indol-3-ylsulfanyl)pyrimidin-2-yl]-3-phenylurea
Show/Hide
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C30H29N7OS
|
1
|
| 1 |
IC50 = 670 nM
|
|
|
|
CP0488026
|
2-[4-(3-acetylanilino)pyrimidin-2-yl]sulfanyl-1-(4-phenylphenyl)ethanone
Show/Hide
|
C26H21N3O2S
|
1
|
| 1 |
IC50 = 740 nM
|
|
|
|
CP0674919
|
(Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenylamino)-methylene]-2,3-dihydro-1H-indole-6-carboxylic Acid Amide
Show/Hide
|
C28H28N4O2
|
1
|
| 1 |
IC50 = 763 nM
|
|
|
|
CP0006184
|
6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(14),4(16),5,7,11(15),12-hexaene-3,10-dione
Show/Hide
|
C14H6O8
|
1
|
| 1 |
IC50 = 790 nM
|
|
|
|
CP0941401
|
(Z)-3-[Phenyl-(4-piperidin-1-ylmethyl-phenylamino)-methylene]-6-pyrrol-1-yl-indolin-2-one
Show/Hide
|
C31H30N4O
|
1
|
| 1 |
IC50 = 791 nM
|
|
|
|
CP0462376
|
2-N-[(3-cyclopropyl-1,2-oxazol-5-yl)methyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
Show/Hide
|
C15H17N7O
|
1
|
| 1 |
IC50 = 794.33 nM
|
|
|
|
CP0086600
|
N-[3-fluoro-4-[2-(1-propan-2-ylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-5-oxo-1-phenylpyrrolidine-3-carboxamide
Show/Hide
|
C30H26FN5O3S
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0578932
|
1-[4-(4-benzylpiperazin-1-yl)-6-(1H-indol-3-ylsulfanyl)pyrimidin-2-yl]-3-(4-methoxyphenyl)urea
Show/Hide
|
C31H31N7O2S
|
1
|
| 1 |
IC50 = 840 nM
|
|
|
|
CP0447489
|
3-anilino-N-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-3-fluorophenyl]-4,4,4-trifluorobutanamide
Show/Hide
|
C26H22F4N4O4
|
1
|
| 1 |
IC50 = 860 nM
|
|
|
|
CP0893467
|
N-Methyl-4-(4-(2-(2-pyridinyl)ethenyl)phenoxy)picolinamide
Show/Hide
|
C20H17N3O2
|
1
|
| 1 |
IC50 = 870 nM
|
|
|
|
CP0218987
|
N-[4-[2-(3-acetylphenyl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-2-oxo-3-phenylimidazolidine-1-carboxamide
Show/Hide
|
C31H23FN4O4S
|
1
|
| 1 |
IC50 = 880 nM
|
|
|
|
CP0579584
|
1-(4-chloro-2-methylphenyl)-3-[4-(1H-indol-3-ylsulfanyl)-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidin-2-yl]urea
Show/Hide
|
C29H27ClN8OS
|
1
|
| 1 |
IC50 = 920 nM
|
|
|
|
CP0368764
|
2-[4-(4-acetylanilino)pyrimidin-2-yl]sulfanyl-1-(4-bromophenyl)ethanone
Show/Hide
|
C20H16BrN3O2S
|
1
|
| 1 |
IC50 = 950 nM
|
|
|
|
CP0540511
|
N-(6-fluoro-1,3-benzothiazol-2-yl)-1,3-diphenylpyrazole-4-carboxamide
Show/Hide
|
C23H15FN4OS
|
1
|
| 1 |
IC50 = 980 nM
|
|
|
|
CP0711847
|
(S,5E,11E)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10-tetrahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione
Show/Hide
|
C19H22O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0383440
|
2-N-[(3-methyl-1,2-oxazol-5-yl)methyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
Show/Hide
|
C13H15N7O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0423867
|
5-bromo-2-N-[(5-methylpyrazin-2-yl)methyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
Show/Hide
|
C14H15BrN8
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0423869
|
5-bromo-4-N-(5-methyl-1H-pyrazol-3-yl)-2-N-prop-2-enylpyrimidine-2,4-diamine
Show/Hide
|
C11H13BrN6
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0380389
|
7-[(2-cyclohexylethyl)oxy]-N-(3,4- dichlorophenyl)-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C23H25Cl2N3O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0380392
|
N-(3,4-dichlorophenyl)-7-({[5-(3,5- dimethylisoxazol-4-yl)-1,2,4-oxadiazol-3- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C23H18Cl2N6O4
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0380393
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[1- (phenylmethyl)-lH-imidazol-2- yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C26H21Cl2N5O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0380394
|
7-({[4-chloro-2-(trifluoromethyl)quinolin-6- yl]methyl}oxy)-N-(3,4-dichlorophenyl)-6- (methyloxy)quinazolin-4-amine
Show/Hide
|
C26H16Cl3F3N4O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0395754
|
N-(3,4-dichlorophenyl)-7-[({4-[4- (diethylamino)phenyl]-1,3-thiazol-2- yl}methyl)oxy]-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C29H27Cl2N5O2S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0395756
|
7-{[(5-chloro-1-benzothien-3-yl)methyl]oxy}- N-(3,4-dichlorophenyl)-6- (methyloxy)quinazolin-4-amine
Show/Hide
|
C24H16Cl3N3O2S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0458250
|
1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-D- glucitol
Show/Hide
|
C22H21BrClN3O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0458726
|
1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-deoxy-D-xylo- hexitol
Show/Hide
|
C21H19BrClN3O4
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0464626
|
1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-L- iditol
Show/Hide
|
C22H21BrClN3O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0464627
|
1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-ethyl-L-iditol
Show/Hide
|
C23H23BrClN3O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0466998
|
N-(3,4-dichlorophenyl)-7-[({3-[4-(1,1- dimethylethyl)phenyl]-1,2,4-oxadiazol-5- yl}methyl)oxy]-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C28H25Cl2N5O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0469169
|
N-(3,4-dichlorophenyl)-7-{[(4- methylmorpholin-2-yl)methyl]oxy}-6- (methyloxy)quinazolin-4-amine
Show/Hide
|
C21H22Cl2N4O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0487719
|
1,4:3,6-dianhydro-5-O-[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-O-methyl-D- xylo-hexitol
Show/Hide
|
C22H21Cl2N3O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0487723
|
N-(3,4-dichlorophenyl)-7-({[2- (dimethylamino)-1,3-thiazol-4-yl]methyl}oxy)- 6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C21H19Cl2N5O2S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0508006
|
7-[(cyclobutylmethyl)oxy]-N-(3,4- dichlorophenyl)-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C20H19Cl2N3O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0508007
|
N-(3,4-dichlorophenyl)-7-({[3- (dimethylamino)-1,2,4-oxadiazol-5- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C20H18Cl2N6O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0509853
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(3- morpholin-4-yl-1,2,4-oxadiazol-5- yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C22H20Cl2N6O4
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0509902
|
N-(3,4-dichlorophenyl)-7-({[3-(2,6- dichlorophenyl)-5-methylisoxazol-4- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C26H18Cl4N4O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0509903
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5- phenyl-1,2,4-oxadiazol-3- yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C24H17Cl2N5O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0513211
|
1,4:3,6-dianhydro-2-O-[4-[(3-chloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]-5-O-methyl-L-iditol
Show/Hide
|
C22H21ClFN3O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0517550
|
1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O- (difluoromethyl)-L-iditol
Show/Hide
|
C22H19BrClF2N3O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0519111
|
7-({[2-(4-chlorophenyl)-1,3-thiazol-4- yl]methyl}oxy)-N-(3,4-dichlorophenyl)-6- (methyloxy)quinazolin-4-amine
Show/Hide
|
C25H17Cl3N4O2S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0525429
|
7-[(cyclohexylmethyl)oxy]-N-(3,4- dichlorophenyl)-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C22H23Cl2N3O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0529544
|
1,1-dimethylethyl 2-[3-({[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-1,2,4- oxadiazol-5-yl]piperidine-1-carboxylate
Show/Hide
|
C28H30Cl2N6O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0530867
|
N-(3,4-dichlorophenyl)-7-{[(1,4- dimethylpiperazin-2-yl)methyl]oxy}-6- (methyloxy)quinazolin-4-amine
Show/Hide
|
C22H25Cl2N5O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0534819
|
7-(cyclopentyloxy)-N-(3,4-dichlorophenyl)-6- (methyloxy)quinazolin-4-amine
Show/Hide
|
C20H19Cl2N3O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0545594
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({2- [4-(trifluoromethyl)phenyl]-1,3-thiazol-4- yl}methyl)oxy]quinazolin-4-amine
Show/Hide
|
C26H17Cl2F3N4O2S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0551136
|
7-{[(3,5-dibromophenyl)methyl]oxy}-N-(3,4- dichlorophenyl)-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C22H15Br2Cl2N3O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0555753
|
5-[2-({[4-[(3,4-dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-1,3- thiazol-4-yl]-2-hydroxybenzamide
Show/Hide
|
C26H19Cl2N5O4S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0563761
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4- pyridin-4-yl-1,3-thiazol-2- yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C24H17Cl2N5O2S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0566217
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4- pyridin-3-yl-1,3-thiazol-2- yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C24H17Cl2N5O2S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0566219
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({5- [2-(methyloxy)phenyl]-1,2,4-oxadiazol-3- yl}methyl)oxy]quinazolin-4-amine
Show/Hide
|
C25H19Cl2N5O4
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0566529
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4- pyridin-2-yl-1,3-thiazol-2- yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C24H17Cl2N5O2S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0566530
|
1,1-dimethylethyl 4-[5-({[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-1,2,4- oxadiazol-3-yl]piperazine-1-carboxylate
Show/Hide
|
C27H29Cl2N7O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0566532
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[5- (4-methylphenyl)-1,3,4-oxadiazol-2- yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C25H19Cl2N5O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0574721
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[(2- morpholin-4-yl-2-oxoethyl)oxy]quinazolin-4- amine
Show/Hide
|
C21H20Cl2N4O4
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0574722
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4- (4-pyrrolidin-1-ylphenyl)-1,3-thiazol-2- yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C29H25Cl2N5O2S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0574725
|
US9796704, Entry 245
Show/Hide
|
C27H20Cl2N4O4S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0848458
|
1,4:3,6-dianhydro-2-O-[4-[(4,5-dichloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-5-O-methyl-L-iditol
Show/Hide
|
C22H20Cl2FN3O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0856499
|
1,1-dimethylethyl 2-(2-{[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}ethyl)-5,5-dimethylmorpholine-4-carboxylate
Show/Hide
|
C28H34Cl2N4O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0869477
|
1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-2-(methylsulfonyl)-L-iditol
Show/Hide
|
C22H21BrClN3O6S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0869479
|
1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-5-O-methyl-5-C-(trifluoromethyl)-D-glucitol
Show/Hide
|
C22H19BrClF3N4O4
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0869480
|
1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-2-[(methylsulfonyl)amino]-L-iditol
Show/Hide
|
C22H22BrClN4O6S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0869481
|
1,4:3,6-dianhydro-2-deoxy-2-fluoro-5-O-[4-{[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]amino}-6-(methyloxy)quinazolin-7-yl]-L-iditol
Show/Hide
|
C26H29F2N5O4
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0869482
|
1,4:3,6-dianhydro-2-deoxy-5-O-[4-{[2,3-dichloro-4-(4-methylpiperazin-1-yl)phenyl]amino}-6-(methyloxy)quinazolin-7-yl]-2-fluoro-L-iditol
Show/Hide
|
C26H28Cl2FN5O4
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0870274
|
1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-2-morpholin-4-yl-L-iditol
Show/Hide
|
C25H26BrClN4O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0870278
|
1,4:3,6-dianhydro-2-deoxy-5-O-[4-{[3,4-dichloro-2-(4-methylpiperazin-1-yl)phenyl]amino}-6-(methyloxy)quinazolin-7-yl]-2-fluoro-L-iditol
Show/Hide
|
C26H28Cl2FN5O4
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0884376
|
1,4:3,6-dianhydro-2-O-[4-[(3,4-dichloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-y1]-5-O-methyl-L-iditol
Show/Hide
|
C22H20Cl2FN3O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0895699
|
1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-L-iditol
Show/Hide
|
C21H19BrClN3O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0895700
|
2-amino-1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-L-iditol
Show/Hide
|
C21H20BrClN4O4
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0897775
|
N-(4-bromo-3-chlorophenyl)-6-(methyloxy)-7-{[(3S,4R)-4-(methyloxy)tetrahydroiuran-3-yl]oxy}quinazolin-4-amine
Show/Hide
|
C20H25N3O7
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0900967
|
1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-D-glucitol
Show/Hide
|
C21H19BrClN3O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0902689
|
1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-2-(4-methylpiperazin-1-yl)-L-iditol
Show/Hide
|
C26H29BrClN5O4
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0903643
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N-(3,4-dichlorophenyl)-7-{[(1-ethyl-4-methylpiperazin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
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C23H27Cl2N5O2
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1
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| 1 |
IC50 = 1000 nM
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CP0903651
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2-O-acetyl-1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-L-iditol
Show/Hide
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C23H21BrClN3O6
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1
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| 1 |
IC50 = 1000 nM
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CP0912075
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1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-5-O-(methylsulfonyl)-D-glucitol
Show/Hide
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C22H21BrClN3O7S
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1
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| 1 |
IC50 = 1000 nM
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CP0920908
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1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-5-S-methyl-5-thio-L-iditol
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C22H21BrClN3O4S
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1
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| 1 |
IC50 = 1000 nM
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CP0920911
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({5-[4-(methyloxy)phenyl]-1,2,4-oxadiazol-3-yl}methyl)oxy]quinazolin-4-amine
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C25H19Cl2N5O4
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1
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| 1 |
IC50 = 1000 nM
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CP0921768
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1,4:3,6-dianhydro-2-O-methyl-5-O-{6-(methyloxy)-4-[(2,3,4-trichlorophenyl)amino]quinazolin-7-yl}-L-iditol
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C22H20Cl3N3O5
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1
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| 1 |
IC50 = 1000 nM
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CP0921771
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dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-L-sorbose ethylene glycol acetal
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C23H21BrClN3O6
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1
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| 1 |
IC50 = 1000 nM
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CP0921772
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N-(3,4-dichlorophenyl)-7-{[(2,6-difluorophenyl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
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C22H15Cl2F2N3O2
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1
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| 1 |
IC50 = 1000 nM
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CP0923756
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1,4:3,6-dianhydro-2-O-[4-[(4-bromo-5-chloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-y1]-5-O-methyl-L-iditol
Show/Hide
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C22H20BrClFN3O5
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1
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| 1 |
IC50 = 1000 nM
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CP0924136
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1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-2-(dimethylamino)-L-iditol
Show/Hide
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C22H22BrClN4O4
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1
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| 1 |
IC50 = 1000 nM
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CP0924137
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2-(acetylamino)-1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-L-iditol
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C23H22BrClN4O5
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1
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| 1 |
IC50 = 1000 nM
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CP0930213
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1,4:3,6-dianhydro-5-O-[4-[(3-chloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro-L-iditol
Show/Hide
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C21H18ClF2N3O4
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1
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| 1 |
IC50 = 1000 nM
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CP0930308
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1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-2-pyrrolidin-1-yl-L-iditol
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C25H26BrClN4O4
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1
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| 1 |
IC50 = 1000 nM
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CP0930309
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1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-2-piperidin-1-yl-L-iditol
Show/Hide
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C26H28BrClN4O4
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1
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| 1 |
IC50 = 1000 nM
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CP0942614
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7-{[(4-acetyl-1-ethylpiperazin-2-yl)methyl]oxy}-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
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C24H27Cl2N5O3
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1
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| 1 |
IC50 = 1000 nM
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CP0947315
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1,4:3,6-dianhydro-2-O-[4-[(3-chloro-2,4-difluorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-5-O-methyl-L-iditol
Show/Hide
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C22H20ClF2N3O5
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1
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| 1 |
IC50 = 1000 nM
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CP0956988
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1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-5-C-(trifluoromethyl)-D-glucitol
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C22H18BrClF3N3O4
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1
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| 1 |
IC50 = 1000 nM
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CP0957460
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N-(3,4-dichlorophenyl)-7-{[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
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C24H18Cl2FN3O4
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1
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| 1 |
IC50 = 1000 nM
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CP0957482
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N-(4-bromo-3-chlorophenyl)-7-{[(3a'S,4R,6'S,6a'R)-2,2-dimethyltetrahydrospiro[1,3-dioxolane-4,3'-furo [3,2-b]iuran]-6'-yl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C25H23BrClN3O6
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1
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| 1 |
IC50 = 1000 nM
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CP0957821
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1,4:3,6-dianhydro-2-O-[4-[(4-bromo-2,3-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-5-O-methyl-L-iditol
Show/Hide
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C22H20BrCl2N3O5
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1
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| 1 |
IC50 = 1000 nM
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CP0963407
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1,4:3,6-dianhydro-2-deoxy-2-fluoro-5-O-(6-(methyloxy)-4-{[4-(4-methylpiperazin-1-yl)phenyl]amino}quinazolin-7-yl)-L-iditol
Show/Hide
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C26H30FN5O4
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1
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| 1 |
IC50 = 1000 nM
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CP0964041
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N-[4-chloro-2,5-bis(methyloxy)phenyl]-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H27ClN4O5
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1
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| 1 |
IC50 = 1000 nM
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CP0964045
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N-(3,4-dichlorophenyl)7-{[(1,4-diethylpiperazin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C24H29Cl2N5O2
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1
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| 1 |
IC50 = 1000 nM
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CP0966520
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N-(3,4-dichlorophenyl)-7-{[(4-octylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C28H36Cl2N4O3
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1
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| 1 |
IC50 = 1000 nM
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CP0966523
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7-[({4-[(4-butylphenyl)carbonyl]morpholin-2-yl}methyl)oxy]-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C31H32Cl2N4O4
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1
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| 1 |
IC50 = 1000 nM
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CP0533464
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4-[2-[4-(4-morpholin-4-ylanilino)pyrimidin-2-yl]sulfanylacetyl]benzonitrile
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C23H21N5O2S
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1
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| 1 |
IC50 = 1100 nM
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CP0560568
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1-[4-(1H-indol-3-ylsulfanyl)-6-piperidin-1-ylpyrimidin-2-yl]-3-(4-methoxyphenyl)urea
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C25H26N6O2S
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1
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| 1 |
IC50 = 1130 nM
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CP0197262
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3-(3-fluoro-4-{thieno[3,2-b]pyridin-7-yloxy}phenyl)-1-(2-phenylacetyl)thiourea
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C22H16FN3O2S2
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1
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| 1 |
IC50 = 1134 nM
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CP0401946
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N-[6-[2-fluoro-4-[[4,4,4-trifluoro-3-(4-fluoroanilino)butanoyl]amino]phenoxy]pyrimidin-4-yl]pyrrolidine-1-carboxamide
Show/Hide
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C25H23F5N6O3
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1
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| 1 |
IC50 = 1200 nM
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CP0568699
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1-[4-(1H-indol-3-ylsulfanyl)-6-morpholin-4-ylpyrimidin-2-yl]-3-phenylurea
Show/Hide
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C23H22N6O2S
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1
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| 1 |
IC50 = 1210 nM
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CP0852537
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N-Cyclohexyl-4-(4-(2-(4-pyridinyl)ethenyl)phenoxy)picolinamide
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C25H25N3O2
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1
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| 1 |
IC50 = 1220 nM
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CP0828600
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(Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenylamino)-methylene]-2,3-dihydro-1H-indole-6-carboxylic Acid Isopropylamide
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C31H34N4O2
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1
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| 1 |
IC50 = 1230 nM
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CP0377544
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5-[[[4-[[5-(3-methoxypropyl)-1H-pyrazol-3-yl]amino]pyrimidin-2-yl]amino]methyl]-1,2-oxazole-3-carboxamide
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C16H20N8O3
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1
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| 1 |
IC50 = 1258.93 nM
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CP0383500
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5-bromo-4-N-[5-(3-methoxypropyl)-1H-pyrazol-3-yl]-2-N-[(3-methyl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine
Show/Hide
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C16H20BrN7O2
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1
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| 1 |
IC50 = 1258.93 nM
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CP0423868
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5-[[[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]amino]methyl]-1,2-oxazole-3-carboxamide
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C13H14N8O2
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1
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| 1 |
IC50 = 1258.93 nM
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CP0893735
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(Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenylamino)-methylene]-2,3-dihydro-1H-indole-6-carboxylic Acid Dimethylamide Hydrochloride
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C30H33ClN4O2
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1
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| 1 |
IC50 = 1312 nM
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CP0565996
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1-[4-anilino-6-(1H-indol-3-ylsulfanyl)pyrimidin-2-yl]-3-(4-methylphenyl)urea
Show/Hide
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C26H22N6OS
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1
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| 1 |
IC50 = 1330 nM
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CP0168489
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4-[[2-[2-(4-methoxyphenyl)-2-oxoethyl]sulfanylpyrimidin-4-yl]amino]benzoic acid
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C20H17N3O4S
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1
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| 1 |
IC50 = 1430 nM
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CP0568702
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1-[4-(3,5-dimethoxyanilino)-6-(1H-indol-3-ylsulfanyl)pyrimidin-2-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C28H26N6O4S
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1
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| 1 |
IC50 = 1430 nM
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CP0565994
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1-(4-chlorophenyl)-3-[4-(1H-indol-3-ylsulfanyl)-6-morpholin-4-ylpyrimidin-2-yl]urea
Show/Hide
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C23H21ClN6O2S
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1
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| 1 |
IC50 = 1440 nM
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CP0641932
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(Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenylamino)-methylene]-2,3-dihydro-1H-indole-6-carboxylic Acid Ethylmethylamide
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C31H34N4O2
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1
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| 1 |
IC50 = 1447 nM
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CP0420462
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5-bromo-4-N-(5-methyl-1H-pyrazol-3-yl)-2-N-(pyridin-2-ylmethyl)pyrimidine-2,4-diamine
Show/Hide
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C14H14BrN7
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1
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| 1 |
IC50 = 1584.89 nM
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CP0423714
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2-N-[(3-cyclopropyl-1,2-oxazol-5-yl)methyl]-4-N-[5-(3-methoxypropyl)-1H-pyrazol-3-yl]pyrimidine-2,4-diamine
Show/Hide
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C18H23N7O2
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1
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| 1 |
IC50 = 1584.89 nM
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CP0568796
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1-[4-(1H-indol-3-ylsulfanyl)-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidin-2-yl]-3-phenylurea
Show/Hide
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C28H26N8OS
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1
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| 1 |
IC50 = 1710 nM
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CP0888594
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(Z)-6-Acetyl-3-[phenyl-(4-piperidin-1-ylmethyl-phenylamino)-methylene]-indolin-2-one
Show/Hide
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C29H29N3O2
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1
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| 1 |
IC50 = 1752 nM
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CP0253735
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N-[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]-3-phenyl-2-sulfanylideneimidazolidine-1-carboxamide
Show/Hide
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C27H21FN6O2S2
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1
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| 1 |
IC50 = 1800 nM
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CP0563881
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1-[4-(4-chloroanilino)-6-(1H-indol-3-ylsulfanyl)pyrimidin-2-yl]-3-phenylurea
Show/Hide
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C25H19ClN6OS
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1
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| 1 |
IC50 = 1810 nM
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CP0533201
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1-(4-chlorophenyl)-3-[4-(1H-indol-3-ylsulfanyl)-6-piperidin-1-ylpyrimidin-2-yl]urea
Show/Hide
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C24H23ClN6OS
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1
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| 1 |
IC50 = 1820 nM
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CP0562084
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1-(4-chlorophenyl)-2-[4-(4-morpholin-4-ylanilino)pyrimidin-2-yl]sulfanylethanone
Show/Hide
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C22H21ClN4O2S
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1
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| 1 |
IC50 = 1900 nM
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CP0565993
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1-[4-(1H-indol-3-ylsulfanyl)-6-morpholin-4-ylpyrimidin-2-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C24H24N6O3S
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1
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| 1 |
IC50 = 1920 nM
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CP0463588
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ethyl 4-[[2-[2-oxo-2-[4-(trifluoromethyl)phenyl]ethyl]sulfanylpyrimidin-4-yl]amino]benzoate
Show/Hide
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C22H18F3N3O3S
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1
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| 1 |
IC50 = 1960 nM
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CP0919445
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(Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenylamino)-methylene]-2,3-dihydro-1H-indole-6-carboxylic Acid Methylamide Hydrochloride
Show/Hide
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C29H31ClN4O2
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1
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| 1 |
IC50 = 2099 nM
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CP0643412
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(Z)-3-(phenyl(4-(piperidin-1-ylmethyl)phenylamino)methylene)-indolin-2-one
Show/Hide
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C27H27N3O
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1
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| 1 |
IC50 = 2112 nM
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CP0511796
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1-[4-(4-benzylpiperazin-1-yl)-6-(1H-indol-3-ylsulfanyl)pyrimidin-2-yl]-3-(2,5-dimethylphenyl)urea
Show/Hide
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C32H33N7OS
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1
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| 1 |
IC50 = 2140 nM
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CP0756569
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(S,9E,15Z)-2-ethyl-4,7-dimethyl-5,11-dimethylene-5,6,7,8,11,12,13,14-octahydrobenzo[14]annulene
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C19H22O5
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1
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| 1 |
IC50 = 2300 nM
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CP0423866
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4-N-[5-(3-methoxypropyl)-1H-pyrazol-3-yl]-2-N-[(3-methyl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine
Show/Hide
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C16H21N7O2
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1
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| 1 |
IC50 = 2511.89 nM
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CP0560569
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1-[4-(1H-indol-3-ylsulfanyl)-6-pyrrolidin-1-ylpyrimidin-2-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C24H24N6O2S
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1
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| 1 |
IC50 = 2610 nM
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CP0425463
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4-(4-methylpiperazin-1-yl)-N-[5-[3-(propylsulfonylamino)phenyl]-1H-pyrazol-3-yl]benzamide
Show/Hide
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C24H30N6O3S
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1
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| 1 |
IC50 = 2720 nM
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CP0487681
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1-[4-anilino-6-(1H-indol-3-ylsulfanyl)pyrimidin-2-yl]-3-phenylurea
Show/Hide
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C25H20N6OS
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1
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| 1 |
IC50 = 2740 nM
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CP0568797
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1-[4-anilino-6-(1H-indol-3-ylsulfanyl)pyrimidin-2-yl]-3-(4-chloro-2-methylphenyl)urea
Show/Hide
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C26H21ClN6OS
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1
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| 1 |
IC50 = 2820 nM
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CP0520598
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5-bromo-4-N-(5-ethyl-1H-pyrazol-3-yl)-2-N-[(3-pyridin-2-yl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine
Show/Hide
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C18H17BrN8O
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1
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| 1 |
IC50 = 3162.28 nM
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CP0565995
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1-[4-(1H-indol-3-ylsulfanyl)-6-pyrrolidin-1-ylpyrimidin-2-yl]-3-phenylurea
Show/Hide
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C23H22N6OS
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1
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| 1 |
IC50 = 3230 nM
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CP0579586
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1-[4-(3,5-dimethoxyanilino)-6-(1H-indol-3-ylsulfanyl)pyrimidin-2-yl]-3-(3,5-dimethoxyphenyl)urea
Show/Hide
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C29H28N6O5S
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1
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| 1 |
IC50 = 3510 nM
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CP0383498
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5-bromo-2-N-[(3-tert-butyl-1,2-oxazol-5-yl)methyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
Show/Hide
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C16H20BrN7O
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1
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| 1 |
IC50 = 3981.07 nM
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CP0563880
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1-[4-(1H-indol-3-ylsulfanyl)-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidin-2-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C29H28N8O2S
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1
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| 1 |
IC50 = 4150 nM
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CP0048963
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(3S,5R)-5-bromo-16-hydroxy-14-methoxy-3-methyl-3,4,5,6,9,10,11,12-octahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione
Show/Hide
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C19H25BrO5
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1
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| 1 |
IC50 = 4300 nM
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CP0572546
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1-[4-(1H-indol-3-ylsulfanyl)-6-piperidin-1-ylpyrimidin-2-yl]-3-phenylurea
Show/Hide
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C24H24N6OS
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1
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| 1 |
IC50 = 4550 nM
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CP0527676
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1-[4-(4-benzylpiperazin-1-yl)-6-(1H-indol-3-ylsulfanyl)pyrimidin-2-yl]-3-(4-chloro-2-methylphenyl)urea
Show/Hide
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C31H30ClN7OS
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1
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| 1 |
IC50 = 4860 nM
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CP0546110
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1-[4-(cyclopropylamino)-6-(1H-indol-3-ylsulfanyl)pyrimidin-2-yl]-3-phenylurea
Show/Hide
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C22H20N6OS
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1
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| 1 |
IC50 = 5220 nM
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CP0447895
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4-[4-(5-ethylsulfonyl-2-methoxyanilino)triazol-1-yl]-2-pyridin-2-ylphenol
Show/Hide
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C22H21N5O4S
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1
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| 1 |
IC50 = 6960 nM
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CP0768561
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(Z)-2-oxo-3-(Phenyl-phenylamino-methylene)-2,3-dihydro-1Hindole-6-carboxylic Acid Methyl Ester
Show/Hide
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C23H18N2O3
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1
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| 1 |
IC50 = 8000 nM
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CP0674918
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(Z)-3-[(1-Methylpiperidin-4-ylamino)-phenyl-methylene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylic Acid Methyl Ester
Show/Hide
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C23H25N3O3
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1
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| 1 |
IC50 > 10000 nM
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CP0727423
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(Z)-methyl 3-((4-(2-(dimethylamino)acetamido)cyclohexylamino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
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C27H32N4O4
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1
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| 1 |
IC50 > 10000 nM
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CP0213913
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4-[[2-[2-(4-nitrophenyl)-2-oxoethyl]sulfanylpyrimidin-4-yl]amino]benzoic acid
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C19H14N4O5S
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1
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| 1 |
IC50 > 10000 nM
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CP0259251
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2-[4-(3-acetylanilino)pyrimidin-2-yl]sulfanyl-1-[4-(trifluoromethyl)phenyl]ethanone
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C21H16F3N3O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0259252
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4-[[2-[2-oxo-2-[4-(trifluoromethyl)phenyl]ethyl]sulfanylpyrimidin-4-yl]amino]benzoic acid
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C20H14F3N3O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0365741
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ethyl 4-[[2-[2-(4-chlorophenyl)-2-oxoethyl]sulfanylpyrimidin-4-yl]amino]benzoate
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C21H18ClN3O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0463587
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4-[[2-[2-(4-bromophenyl)-2-oxoethyl]sulfanylpyrimidin-4-yl]amino]benzoic acid
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C19H14BrN3O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0383495
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[5-[[[5-bromo-4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]amino]methyl]-1,2-oxazol-3-yl]-pyrrolidin-1-ylmethanone
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C17H19BrN8O2
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1
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| 1 |
IC50 = 15848.93 nM
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CP0437838
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[3-[[2-[(3-methyl-1,2-oxazol-5-yl)methylamino]pyrimidin-4-yl]amino]-1H-pyrazol-5-yl]methanol
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C13H15N7O2
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1
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| 1 |
IC50 = 19952.62 nM
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CP0380387
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1,4:3,6-dianhydro-2-O-[4-[(3-bromo-2- methylphenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-L- iditol
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C23H24BrN3O5
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1
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| 1 |
IC50 > 20000 nM
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CP0493312
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1,4:3,6-dianhydro-2-O-[4-[(3-chloro-2- methylphenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-L- iditol
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C23H24ClN3O5
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1
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| 1 |
IC50 > 20000 nM
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CP0233573
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(3S,5R,Z)-5-bromo-16-hydroxy-14-methoxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione
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C19H23BrO5
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1
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| 1 |
IC50 = 24000 nM
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CP0139001
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N-(4-fluorophenyl)-1-methyl-3-[[methyl-[2-(4-phenylphenyl)ethyl]amino]methyl]indole-5-carboxamide
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C32H30FN3O
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1
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| 1 |
IC50 = 31000 nM
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CP0009041
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5-propan-2-yl-7,8-dihydro-6H-indeno[1,2-b]indole-9,10-dione
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C18H17NO2
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1
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| 1 |
IC50 > 35000 nM
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CP0477250
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4-[4-(5-ethylsulfonyl-2-methoxyanilino)triazol-1-yl]-2-(1H-pyrrol-3-yl)phenol
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C21H21N5O4S
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1
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| 1 |
IC50 = 40100 nM
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CP0515007
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N-(5-ethylsulfonyl-2-methoxyphenyl)-1-(3-pyridin-2-ylphenyl)triazol-4-amine
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C22H21N5O3S
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1
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| 1 |
IC50 = 42000 nM
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CP0054958
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(3S,5R,Z)-5-chloro-16-hydroxy-14-methoxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione
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C19H23ClO5
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1
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| 1 |
IC50 = 82000 nM
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CP0241066
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(3S,5R)-5-chloro-16-hydroxy-14-methoxy-3-methyl-3,4,5,6,9,10,11,12-octahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione
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C19H25ClO5
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1
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| 1 |
IC50 = 93000 nM
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CP0180683
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(3S,5R,E)-5-bromo-16-hydroxy-14-methoxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione
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C19H23BrO5
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1
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| 1 |
IC50 > 100000 nM
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CP0474858
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N-(5-ethylsulfonyl-2-methoxyphenyl)-1-(3-pyridin-3-ylphenyl)triazol-4-amine
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C22H21N5O3S
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1
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| 1 |
IC50 > 100000 nM
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CP0489996
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[4-[4-(5-ethylsulfonyl-2-methoxyanilino)triazol-1-yl]-2-naphthalen-1-ylphenyl]urea
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C28H26N6O4S
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1
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| 1 |
IC50 > 100000 nM
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CP0956578
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(Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenylamino)-methylene]-2,3-dihydro-1H-indole-6-carboxylic Acid
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C28H27N3O3
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1
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| 1 |
IC50 > 1000 nM
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CP0396775
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N-[5-[3-[(4-methylphenyl)sulfonylamino]phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide
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C28H30N6O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0396776
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N-[5-[3-(ethylsulfonylamino)phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide
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C23H28N6O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0396777
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4-(4-methylpiperazin-1-yl)-N-[5-[3-(propan-2-ylsulfonylamino)phenyl]-1H-pyrazol-3-yl]benzamide
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C24H30N6O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0425465
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N-[5-[3-[(4-chlorophenyl)sulfonylamino]phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide
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C27H27ClN6O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0425466
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N-[5-[3-(benzenesulfonamido)phenyl]-1H-pyrazol-3-yl]-4-(2-morpholin-4-ylethoxy)benzamide
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C28H29N5O5S
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1
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| 1 |
IC50 > 1000 nM
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CP0459938
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N-[5-[3-(benzenesulfonamido)phenyl]-1H-pyrazol-3-yl]-3-morpholin-4-ylbenzamide
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C26H25N5O4S
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1
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| 1 |
IC50 > 1000 nM
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CP0381462
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N-[5-[3-chloro-4-[(5-methyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide
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C26H27ClN8O3
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1
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| 1 |
IC50 > 1000 nM
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CP0458197
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N-[4-[3-[[4-(4-methylpiperazin-1-yl)benzoyl]amino]-1H-pyrazol-5-yl]phenyl]pyrrolidine-1-carboxamide
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C26H31N7O2
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1
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| 1 |
IC50 > 1000 nM
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CP0382324
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N-[4-[2-[[6-(4-ethylpiperazin-1-yl)-2-methylpyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]benzamide
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C27H29N7OS
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1
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| 1 |
IC50 > 1000 nM
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CP0542537
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(2S,4R)-1-[(2S)-2-[[7-[3-amino-4-[3-[(3-propan-2-ylphenyl)carbamoylamino]phenyl]indazol-1-yl]-7-oxoheptanoyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
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C52H61N9O6S
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1
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| 1 |
IC50 > 1000 nM
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CP0558035
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(2S,4R)-1-[(2S)-2-[[16-[3-amino-4-[3-[(3-propan-2-ylphenyl)carbamoylamino]phenyl]indazol-1-yl]-16-oxohexadecanoyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
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C61H79N9O6S
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1
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| 1 |
IC50 > 1000 nM
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CP0570924
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(2S,4R)-1-[(2S)-2-[[7-[3-amino-4-[4-[(2-fluoro-5-methylphenyl)carbamoylamino]phenyl]indazol-1-yl]-7-oxoheptanoyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
Show/Hide
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C50H56FN9O6S
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1
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| 1 |
IC50 > 1000 nM
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CP0891947
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(Z)-N-{2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenylamino)-methylene]-2,3-dihydro-1H-indol-6-yl}-acetamide Hydrochloride
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C29H31ClN4O2
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1
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| 1 |
IC50 > 3000 nM
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