General Information of the Compound
| Compound ID |
CP0423867
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| Compound Name |
5-bromo-2-N-[(5-methylpyrazin-2-yl)methyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
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| Structure |
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| Formula |
C14H15BrN8
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| Molecular Weight |
375.234
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| Canonical SMILES |
Cc1cc(Nc2nc(NCc3cnc(C)cn3)ncc2Br)[nH]n1
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| InChI |
InChI=1S/C14H15BrN8/c1-8-3-12(23-22-8)20-13-11(15)7-19-14(21-13)18-6-10-5-16-9(2)4-17-10/h3-5,7H,6H2,1-2H3,(H3,18,19,20,21,22,23)
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| InChIKey |
SRUVCUHDFMECCJ-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01104, Insulin-like growth factor 1 receptor
Protein ID: PT00864, Vascular endothelial growth factor receptor 2