General Information of the Compound
| Compound ID |
CP0487720
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| Compound Name |
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[(1,3- thiazol-4-ylmethyl)oxy]quinazolin-4-amine
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| Structure |
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| Formula |
C19H14Cl2N4O2S
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| Molecular Weight |
433.32
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| Canonical SMILES |
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cscn1
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| InChI |
InChI=1S/C19H14Cl2N4O2S/c1-26-17-5-13-16(6-18(17)27-7-12-8-28-10-24-12)22-9-23-19(13)25-11-2-3-14(20)15(21)4-11/h2-6,8-10H,7H2,1H3,(H,22,23,25)
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| InChIKey |
SHQICENFGOEXMY-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01142, Vascular endothelial growth factor receptor 1
Protein ID: PT00864, Vascular endothelial growth factor receptor 2