General Information of the Compound
| Compound ID |
CP0515483
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| Compound Name |
N-(3,4-dichlorophenyl)-6-(methyloxy)-7- [(pyridin-3-ylmethyl)oxy]quinazolin-4-amine
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| Structure |
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| Formula |
C21H16Cl2N4O2
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| Molecular Weight |
427.291
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| Canonical SMILES |
COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cccnc1
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| InChI |
InChI=1S/C21H16Cl2N4O2/c1-28-19-8-15-18(9-20(19)29-11-13-3-2-6-24-10-13)25-12-26-21(15)27-14-4-5-16(22)17(23)7-14/h2-10,12H,11H2,1H3,(H,25,26,27)
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| InChIKey |
LUAHOZHPDVOBIY-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01142, Vascular endothelial growth factor receptor 1
Protein ID: PT00864, Vascular endothelial growth factor receptor 2