Brief Information of the Compound and Protein
Compound Name
1-(4-chloro-2-methylphenyl)-3-[4-(cyclopropylamino)-6-(1H-indol-3-ylsulfanyl)pyrimidin-2-yl]urea
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Canonical SMILES
Cc1cc(Cl)ccc1NC(=O)Nc1nc(NC2CC2)cc(Sc2c[nH]c3ccccc23)n1
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Compound Formula C23H21ClN6OS
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 440 nM
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