Brief Information of the Compound and Protein
Compound Name
1-[2-Chloro-4-({5-[2-(2-hydroxyethoxy)ethyl]-5H-pyrrolo [3,2-d]pyrimidin-4-yl}oxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea
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PubChem ID
CID: 52946496
Canonical SMILES
OCCOCCn1ccc2ncnc(Oc3ccc(NC(=O)Nc4cccc(c4)C(F)(F)F)c(Cl)c3)c12
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Compound Formula C24H21ClF3N5O4
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 2.7 nM
   TI
   LI
   LO
   TS