General Information of the Compound
| Compound ID |
CP0282509
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| Compound Name |
N-[4-[2-(1-ethylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-3-(2-methoxyphenyl)-2-oxoimidazolidine-1-carboxamide
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| Structure |
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| Formula |
C29H25FN6O4S
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| Molecular Weight |
572.622
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| Canonical SMILES |
CCn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)N4CCN(C4=O)c4ccccc4OC)cc3F)c2s1
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| InChI |
InChI=1S/C29H25FN6O4S/c1-3-34-16-21(32-17-34)26-15-20-27(41-26)25(10-11-31-20)40-23-9-8-18(14-19(23)30)33-28(37)36-13-12-35(29(36)38)22-6-4-5-7-24(22)39-2/h4-11,14-17H,3,12-13H2,1-2H3,(H,33,37)
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| InChIKey |
NXLXVWKXBAWMDC-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01201, Hepatocyte growth factor receptor
Protein ID: PT00864, Vascular endothelial growth factor receptor 2