Brief Information of the Compound and Protein
Compound Name
N-[6-[4-[(4-anilino-1,1,1-trifluoro-4-oxobutan-2-yl)amino]-2-fluorophenoxy]pyrimidin-4-yl]pyrrolidine-1-carboxamide
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PubChem ID
CID: 44177803
SID: 85166879
Canonical SMILES
Fc1cc(NC(CC(=O)Nc2ccccc2)C(F)(F)F)ccc1Oc1cc(NC(=O)N2CCCC2)ncn1
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Compound Formula C25H24F4N6O3
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 40 nM
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