Brief Information of the Compound and Protein
Compound Name
N-[6-[2-fluoro-4-[[4,4,4-trifluoro-3-(4-fluoroanilino)butanoyl]amino]phenoxy]pyrimidin-4-yl]pyrrolidine-1-carboxamide
    Show/Hide
PubChem ID
CID: 44177697
SID: 85166766
Canonical SMILES
Fc1ccc(NC(CC(=O)Nc2ccc(Oc3cc(NC(=O)N4CCCC4)ncn3)c(F)c2)C(F)(F)F)cc1
    Show/Hide
Compound Formula C25H23F5N6O3
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS