General Information of the Compound
| Compound ID |
CP0420465
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| Compound Name |
5-bromo-2-N-[2-(furan-2-yl)ethyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
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| Structure |
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| Formula |
C14H15BrN6O
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| Molecular Weight |
363.219
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| Canonical SMILES |
Cc1cc(Nc2nc(NCCc3ccco3)ncc2Br)[nH]n1
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| InChI |
InChI=1S/C14H15BrN6O/c1-9-7-12(21-20-9)18-13-11(15)8-17-14(19-13)16-5-4-10-3-2-6-22-10/h2-3,6-8H,4-5H2,1H3,(H3,16,17,18,19,20,21)
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| InChIKey |
WCEVHFFJWJXDEU-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01104, Insulin-like growth factor 1 receptor
Protein ID: PT00864, Vascular endothelial growth factor receptor 2