General Information of the Compound
| Compound ID |
CP0377544
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| Compound Name |
5-[[[4-[[5-(3-methoxypropyl)-1H-pyrazol-3-yl]amino]pyrimidin-2-yl]amino]methyl]-1,2-oxazole-3-carboxamide
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| Structure |
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| Formula |
C16H20N8O3
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| Molecular Weight |
372.389
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| Canonical SMILES |
COCCCc1cc(Nc2ccnc(NCc3cc(no3)C(N)=O)n2)[nH]n1
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| InChI |
InChI=1S/C16H20N8O3/c1-26-6-2-3-10-7-14(23-22-10)20-13-4-5-18-16(21-13)19-9-11-8-12(15(17)25)24-27-11/h4-5,7-8H,2-3,6,9H2,1H3,(H2,17,25)(H3,18,19,20,21,22,23)
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| InChIKey |
ALJUSBALYODRPB-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01104, Insulin-like growth factor 1 receptor
Protein ID: PT00864, Vascular endothelial growth factor receptor 2