General Information of the Compound
| Compound ID |
CP0489454
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| Compound Name |
1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-pyridin-4-ylurea
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| Structure |
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| Formula |
C19H15ClN6O2
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| Molecular Weight |
394.822
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| Canonical SMILES |
Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4ccncc4)c(Cl)c3)c12
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| InChI |
InChI=1S/C19H15ClN6O2/c1-26-9-6-16-17(26)18(23-11-22-16)28-13-2-3-15(14(20)10-13)25-19(27)24-12-4-7-21-8-5-12/h2-11H,1H3,(H2,21,24,25,27)
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| InChIKey |
ROZXJVHSZADRDQ-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT00864, Vascular endothelial growth factor receptor 2