| Compound ID |
Compound Name |
Compound Formula |
|
CP0393174
|
1-(16-fluoro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7,9,11,15,17-hexaen-4-yl)-N,N-dimethylmethanamine
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|
C19H21FN2O
|
1
|
| 1 |
IC50 = 1.288 nM
|
|
|
|
CP0453941
|
1-(15-fluoro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7,9,11,15,17-hexaen-4-yl)-N,N-dimethylmethanamine
Show/Hide
|
C19H21FN2O
|
1
|
| 1 |
IC50 = 1.738 nM
|
|
|
|
CP0405608
|
1-(11-fluoro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaen-4-yl)-N,N-dimethylmethanamine
Show/Hide
|
C19H21FN2O
|
1
|
| 1 |
IC50 = 2.291 nM
|
|
|
|
CP0105756
|
1-(17-chloro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7,9,11,15,17-hexaen-4-yl)-N,N-dimethylmethanamine
Show/Hide
|
C19H21ClN2O
|
1
|
| 1 |
IC50 = 2.344 nM
|
|
|
|
CP0134845
|
1-(17-fluoro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7,9,11,15,17-hexaen-4-yl)-N,N-dimethylmethanamine
Show/Hide
|
C19H21FN2O
|
1
|
| 1 |
IC50 = 2.57 nM
|
|
|
|
CP0384022
|
4-(pyrrolidin-1-ylmethyl)-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaene
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|
C21H24N2O
|
1
|
| 1 |
IC50 = 3.02 nM
|
|
|
|
CP0026495
|
CHEBI:51137
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|
C18H20N2
|
1
|
| 1 |
IC50 = 3.388 nM
|
|
|
|
CP0464753
|
1-(9-fluoro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaen-4-yl)-N,N-dimethylmethanamine
Show/Hide
|
C19H21FN2O
|
1
|
| 1 |
IC50 = 3.802 nM
|
|
|
|
CP0123725
|
N,N-dimethyl-1-(17-methyl-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7,9,11,15,17-hexaen-4-yl)methanamine
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
IC50 = 5.888 nM
|
|
|
|
CP0464885
|
N,N-dimethyl-1-(15-methyl-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl)methanamine
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|
C20H24N2O
|
1
|
| 1 |
IC50 = 6.026 nM
|
|
|
|
CP0734983
|
Dimethyl-(2,3,3a,8-tetrahydro-1-oxa-12b-aza-dibenzo[e,h]azulen-2-ylmethyl)-amine
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|
C19H22N2O
|
1
|
| 1 |
IC50 = 6.761 nM
|
|
|
|
CP0431008
|
N,N-dimethyl-1-(17-phenyl-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7,9,11,15,17-hexaen-4-yl)methanamine
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|
C25H26N2O
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
|
CP0183894
|
N-methyl-1-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl)methanamine
Show/Hide
|
C18H20N2O
|
1
|
| 1 |
IC50 = 10.72 nM
|
|
|
|
CP0435998
|
N,N-dimethyl-1-(8-methyl-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl)methanamine
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
IC50 = 11.75 nM
|
|
|
|
CP0402198
|
N-ethyl-N-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-ylmethyl)ethanamine
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|
C21H26N2O
|
1
|
| 1 |
IC50 = 13.49 nM
|
|
|
|
CP0372936
|
1-(9-methoxy-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaen-4-yl)-N,N-dimethylmethanamine
Show/Hide
|
C20H24N2O2
|
1
|
| 1 |
IC50 = 14.45 nM
|
|
|
|
CP0497667
|
1-(18-chloro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7,9,11,15,17-hexaen-4-yl)-N,N-dimethylmethanamine
Show/Hide
|
C19H21ClN2O
|
1
|
| 1 |
IC50 = 15.49 nM
|
|
|
|
CP0497647
|
N,N-dimethyl-1-(10-methyl-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaen-4-yl)methanamine
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
IC50 = 15.85 nM
|
|
|
|
CP0091879
|
1-(9,17-difluoro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7(12),8,10,15,17-hexaen-4-yl)-N,N-dimethylmethanamine
Show/Hide
|
C19H20F2N2O
|
1
|
| 1 |
IC50 = 16.98 nM
|
|
|
|
CP0475727
|
4-(morpholin-4-ylmethyl)-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaene
Show/Hide
|
C21H24N2O2
|
1
|
| 1 |
IC50 = 26.3 nM
|
|
|
|
CP0404509
|
N,N-dimethyl-1-[11-(trifluoromethyl)-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaen-4-yl]methanamine
Show/Hide
|
C20H21F3N2O
|
1
|
| 1 |
IC50 = 37.15 nM
|
|
|
|
CP0392920
|
N,N-dimethyl-1-[8-(trifluoromethyl)-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaen-4-yl]methanamine
Show/Hide
|
C20H21F3N2O
|
1
|
| 1 |
IC50 = 47.86 nM
|
|
|
|
CP0044035
|
1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine
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|
C16H19ClN2
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0094561
|
N,N-dimethyl-2-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl)ethanamine
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
IC50 = 83.18 nM
|
|
|
|
CP0400980
|
1-(17-chloro-3,13-dioxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7,9,11,15,17-hexaen-4-yl)-N,N-dimethylmethanamine
Show/Hide
|
C18H19ClN2O2
|
1
|
| 1 |
IC50 = 102.33 nM
|
|
|
|
CP0392599
|
N-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-ylmethyl)-N-propan-2-ylpropan-2-amine
Show/Hide
|
C23H30N2O
|
1
|
| 1 |
IC50 = 151.36 nM
|
|
|
|
CP0467988
|
3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-ylmethanamine
Show/Hide
|
C17H18N2O
|
1
|
| 1 |
IC50 = 199.53 nM
|
|
|
|
CP0438133
|
N,N-dimethyl-3-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl)propan-1-amine
Show/Hide
|
C21H26N2O
|
1
|
| 1 |
IC50 = 676.08 nM
|
|
|
|
CP0399800
|
10-(6-(diethylamino)hexyl)acridin-9(10H)-one
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|
C23H30N2O
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
|
CP0422415
|
4-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaene
Show/Hide
|
C27H28ClN3O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0437491
|
2,2,2-trifluoro-N-methyl-N-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-ylmethyl)acetamide
Show/Hide
|
C20H19F3N2O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0460072
|
N,N-dimethyl-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaene-4-carboxamide
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|
C19H20N2O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0461043
|
4-[(4-phenylpiperazin-1-yl)methyl]-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaene
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|
C27H29N3O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0461320
|
2-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-ylmethyl)isoindole-1,3-dione
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|
C25H20N2O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0463614
|
N,N-dimethyl-4-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl)butan-1-amine
Show/Hide
|
C22H28N2O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0464735
|
4-(piperazin-1-ylmethyl)-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaene
Show/Hide
|
C21H25N3O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0476618
|
4-(1,3-dihydroisoindol-2-ylmethyl)-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaene
Show/Hide
|
C25H24N2O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0383066
|
1-(11-chloro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaen-4-yl)-N,N-dimethylmethanamine
Show/Hide
|
C19H21ClN2O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0508933
|
1-(8-fluoro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaen-4-yl)-N,N-dimethylmethanamine
Show/Hide
|
C19H21FN2O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0515871
|
N,N-dimethyl-1-[9-(trifluoromethyl)-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaen-4-yl]methanamine
Show/Hide
|
C20H21F3N2O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0367946
|
2-[[(2R)-1-butylpyrrolidin-2-yl]methyl]-4-[(4-chlorophenyl)methyl]phthalazin-1-one
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|
C24H28ClN3O
|
2
|
| 1 |
Kd = 0.03981 nM
|
|
|
| 2 |
Ki = 0.912 nM
|
|
|
|
CP0042388
|
2-[[(2R)-1-butylpyrrolidin-2-yl]methyl]-4-[(4-chlorophenyl)methyl]pyrido[3,4-d]pyridazin-1-one
Show/Hide
|
C23H27ClN4O
|
2
|
| 1 |
Kd = 0.1 nM
|
|
|
| 2 |
Ki = 0.3981 nM
|
|
|
|
CP0339883
|
4-[(4-chlorophenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C21H22ClN3O
|
3
|
| 1 |
Kd = 0.1 nM
|
|
|
| 2 |
Ki = 0.1585 nM
|
|
|
| 3 |
Ki = 0.1622 nM
|
|
|
|
CP0294233
|
4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-phthalazin-1-one
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|
C22H24ClN3O
|
3
|
| 1 |
Kd = 0.1995 nM
|
|
|
| 2 |
Ki = 1.202 nM
|
|
|
| 3 |
Ki = 1.259 nM
|
|
|
|
CP0473010
|
N-[2-[(2R)-2-[[4-[(4-chlorophenyl)methyl]-1-oxophthalazin-2-yl]methyl]pyrrolidin-1-yl]ethyl]-4-methoxybutanamide;dihydrochloride
Show/Hide
|
C27H35Cl3N4O3
|
1
|
| 1 |
Kd = 0.1995 nM
|
|
|
|
CP0852619
|
N-(4-(4-(6-butylquinolin-8-yloxy)piperidin-1-yl)butyl)propane-1-sulfonamide dihydrochloride
Show/Hide
|
C25H41Cl2N3O3S
|
1
|
| 1 |
Kd = 0.1995 nM
|
|
|
|
CP0339444
|
4-[(4-chlorophenyl)methyl]-2-[[(2R)-1-(2-methoxyethyl)pyrrolidin-2-yl]methyl]pyrido[3,4-d]pyridazin-1-one
Show/Hide
|
C22H25ClN4O2
|
2
|
| 1 |
Kd = 0.2512 nM
|
|
|
| 2 |
Ki = 0.2512 nM
|
|
|
|
CP0404568
|
6-butyl-8-[1-(3-tert-butylsulfonylpropyl)piperidin-4-yl]oxyquinoline
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|
C25H38N2O3S
|
1
|
| 1 |
Kd = 0.263 nM
|
|
|
|
CP0159108
|
4-[(4-chlorophenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]pyrido[3,4-d]pyridazin-1-one
Show/Hide
|
C20H21ClN4O
|
2
|
| 1 |
Kd = 0.3162 nM
|
|
|
| 2 |
Ki = 0.3467 nM
|
|
|
|
CP0339445
|
7-[[(2R)-1-butylpyrrolidin-2-yl]methyl]-5-[(4-chlorophenyl)methyl]pyrido[2,3-d]pyridazin-8-one
Show/Hide
|
C23H27ClN4O
|
2
|
| 1 |
Kd = 0.3162 nM
|
|
|
| 2 |
Ki = 0.631 nM
|
|
|
|
CP0357237
|
8-[(4-chlorophenyl)methyl]-6-[[(2R)-1-methylpyrrolidin-2-yl]methyl]pyrido[2,3-d]pyridazin-5-one
Show/Hide
|
C20H21ClN4O
|
2
|
| 1 |
Kd = 0.3162 nM
|
|
|
| 2 |
Ki = 0.3162 nM
|
|
|
|
CP0862616
|
6-butyl-8-(1-(3-(ethylsulfonyl)propyl)piperidin-4-yloxy)quinoline dihydrochloride
Show/Hide
|
C23H36Cl2N2O3S
|
1
|
| 1 |
Kd = 0.3467 nM
|
|
|
|
CP0905694
|
N-(4-(4-(6-butylquinolin-8-yloxy)piperidin-1-yl)butyl)methanesulfonamide dihydrochloride
Show/Hide
|
C23H37Cl2N3O3S
|
1
|
| 1 |
Kd = 0.3981 nM
|
|
|
|
CP0946943
|
6-butyl-8-(1-(3-(isopropylsulfonyl)propyl)piperidin-4-yloxy)quinoline dihydrochloride
Show/Hide
|
C24H38Cl2N2O3S
|
1
|
| 1 |
Kd = 0.3981 nM
|
|
|
|
CP0352451
|
5-[(4-chlorophenyl)methyl]-7-[[(2R)-1-methylpyrrolidin-2-yl]methyl]pyrido[2,3-d]pyridazin-8-one
Show/Hide
|
C20H21ClN4O
|
2
|
| 1 |
Kd = 0.5012 nM
|
|
|
| 2 |
Ki = 0.3548 nM
|
|
|
|
CP0702373
|
N-(4-{4-[(6-Butyl-8-quinolinyl)oxy]-1-piperidinyl}butyl)ethanesulfonamide dihydrochloride
Show/Hide
|
C24H39Cl2N3O3S
|
1
|
| 1 |
Kd = 0.537 nM
|
|
|
|
CP0947001
|
N-tert-butyl-3-(4-(6-butylquinolin-8-yloxy)piperidin-1-yl)propane-1-sulfonamide dihydrochloride
Show/Hide
|
C25H41Cl2N3O3S
|
1
|
| 1 |
Kd = 0.631 nM
|
|
|
|
CP0862615
|
6-butyl-8-(1-(3-(propylsulfonyl)propyl)piperidin-4-yloxy)quinoline dihydrochloride
Show/Hide
|
C24H38Cl2N2O3S
|
1
|
| 1 |
Kd = 0.7413 nM
|
|
|
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CP0056747
|
4-[(4-Chlorophenyl)methyl]-2-({(2R)-1-[4-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)butyl]-2-pyrrolidinyl}methyl)-1(2H)-phthalazinone
Show/Hide
|
C39H49ClN4O2
|
2
|
| 1 |
Kd = 0.7943 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
|
CP0179680
|
5-[(4-chlorophenyl)methyl]-7-[[(2R)-1-(2-methoxyethyl)pyrrolidin-2-yl]methyl]pyrido[2,3-d]pyridazin-8-one
Show/Hide
|
C22H25ClN4O2
|
2
|
| 1 |
Kd = 0.7943 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0878528
|
N-(4-(4-(6-butylquinolin-8-yloxy)piperidin-1-yl)butyl)-2-methylpropane-1-sulfonamide dihydrochloride
Show/Hide
|
C26H43Cl2N3O3S
|
1
|
| 1 |
Kd = 0.8318 nM
|
|
|
|
CP0159107
|
2-[[(2R)-1-[4-[4-[3-(azepan-1-yl)propoxy]phenyl]butyl]pyrrolidin-2-yl]methyl]-4-[(4-chlorophenyl)methyl]pyrido[3,4-d]pyridazin-1-one
Show/Hide
|
C38H48ClN5O2
|
2
|
| 1 |
Kd = 1 nM
|
|
|
| 2 |
Ki = 17.38 nM
|
|
|
|
CP0493726
|
4-[4-(6-butylquinolin-8-yl)oxypiperidin-1-yl]-N-propylbutane-1-sulfonamide
Show/Hide
|
C25H39N3O3S
|
1
|
| 1 |
Kd = 1 nM
|
|
|
|
CP0870344
|
N-(4-(4-(6-butylquinolin-8-yloxy)piperidin-1-yl)butyl)cyclohexanesulfonamide dihydrochloride
Show/Hide
|
C28H45Cl2N3O3S
|
1
|
| 1 |
Kd = 1 nM
|
|
|
|
CP0951179
|
N-(4-(4-(6-butylquinolin-8-yloxy)piperidin-1-yl)butyl)-N-methylethanesulfonamide dihydrochloride
Show/Hide
|
C25H41Cl2N3O3S
|
1
|
| 1 |
Kd = 1 nM
|
|
|
|
CP0377778
|
2-[[(2R)-1-[4-[4-[3-(azepan-1-yl)propoxy]phenyl]butyl]pyrrolidin-2-yl]methyl]-4-[(4-methoxyphenyl)methyl]phthalazin-1-one
Show/Hide
|
C40H52N4O3
|
2
|
| 1 |
Kd = 1.259 nM
|
|
|
| 2 |
Ki = 7.943 nM
|
|
|
|
CP0466023
|
2-[[(2R)-1-[5-[4-[3-(azepan-1-yl)propoxy]phenyl]pentyl]pyrrolidin-2-yl]methyl]-4-[(4-chlorophenyl)methyl]phthalazin-1-one
Show/Hide
|
C40H51ClN4O2
|
2
|
| 1 |
Kd = 1.259 nM
|
|
|
| 2 |
Ki = 12.59 nM
|
|
|
|
CP0946944
|
N-(3-(4-(6-butylquinolin-8-yloxy)piperidin-1-yl)propyl)ethanesulfonamide dihydrochloride
Show/Hide
|
C23H37Cl2N3O3S
|
1
|
| 1 |
Kd = 1.259 nM
|
|
|
|
CP0853877
|
6-butyl-8-(1-(4-(tert-butylsulfonyl)butyl)piperidin-4-yloxy)quinoline dihydrochloride
Show/Hide
|
C26H42Cl2N2O3S
|
1
|
| 1 |
Kd = 1.413 nM
|
|
|
|
CP0450305
|
3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]-6-butylquinolin-2-yl]propanoic acid
Show/Hide
|
C37H52N4O3
|
2
|
| 1 |
Kd = 1.585 nM
|
|
|
| 2 |
Ki = 12.59 nM
|
|
|
|
CP0460793
|
N-tert-butyl-2-[4-(6-butylquinolin-8-yl)oxypiperidin-1-yl]ethanesulfonamide
Show/Hide
|
C24H37N3O3S
|
1
|
| 1 |
Kd = 1.995 nM
|
|
|
|
CP0905695
|
N-(4-(4-(6-butylquinolin-8-yloxy)piperidin-1-yl)butyl)propane-2-sulfonamide dihydrochloride
Show/Hide
|
C25H41Cl2N3O3S
|
1
|
| 1 |
Kd = 1.995 nM
|
|
|
|
CP0862516
|
N-(2-(4-(6-butylquinolin-8-yloxy)piperidin-1-yl)ethyl)ethanesulfonamide dihydrochloride
Show/Hide
|
C22H35Cl2N3O3S
|
1
|
| 1 |
Kd = 2.089 nM
|
|
|
|
CP0056748
|
1-[(4-chlorophenyl)methyl]-3-[[(2R)-1-methylpyrrolidin-2-yl]methyl]pyrido[3,4-d]pyridazin-4-one
Show/Hide
|
C20H21ClN4O
|
2
|
| 1 |
Kd = 2.512 nM
|
|
|
| 2 |
Ki = 0.6918 nM
|
|
|
|
CP0464411
|
3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]-6-ethylquinolin-2-yl]propanoic acid
Show/Hide
|
C35H48N4O3
|
2
|
| 1 |
Kd = 2.512 nM
|
|
|
| 2 |
Ki = 15.85 nM
|
|
|
|
CP0915497
|
6-butyl-8-(1-(2-(ethylsulfonyl)ethyl)piperidin-4-yloxy)quinoline dihydrochloride
Show/Hide
|
C22H34Cl2N2O3S
|
1
|
| 1 |
Kd = 3.715 nM
|
|
|
|
CP0377779
|
2-[[(2R)-1-[4-[4-[3-(azepan-1-yl)propoxy]phenyl]butyl]pyrrolidin-2-yl]methyl]-4-[(4-hydroxyphenyl)methyl]phthalazin-1-one
Show/Hide
|
C39H50N4O3
|
2
|
| 1 |
Kd = 3.981 nM
|
|
|
| 2 |
Ki = 12.59 nM
|
|
|
|
CP0148523
|
8-[(4-chlorophenyl)methyl]-6-[[(2R)-1-methylpyrrolidin-2-yl]methyl]pyrazino[2,3-d]pyridazin-5-one
Show/Hide
|
C19H20ClN5O
|
2
|
| 1 |
Kd = 3.981 nM
|
|
|
| 2 |
Ki = 1.288 nM
|
|
|
|
CP0450309
|
8-[4-[4-[4-[3-(azepan-1-yl)propoxy]phenyl]butyl]piperazin-1-yl]quinoline
Show/Hide
|
C32H44N4O
|
2
|
| 1 |
Kd = 5.012 nM
|
|
|
| 2 |
Ki = 15.85 nM
|
|
|
|
CP0468325
|
3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]-6-benzylquinolin-2-yl]propanoic acid
Show/Hide
|
C40H50N4O3
|
2
|
| 1 |
Kd = 6.31 nM
|
|
|
| 2 |
Ki = 25.12 nM
|
|
|
|
CP0450310
|
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline
Show/Hide
|
C30H40N4O
|
2
|
| 1 |
Kd = 10 nM
|
|
|
| 2 |
Ki = 19.95 nM
|
|
|
|
CP0032319
|
8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Show/Hide
|
C19H19ClN2
|
1
|
| 1 |
Kd = 24 nM
|
|
|
|
CP0578034
|
13-chloro-2-piperidin-4-ylidene-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-9-ol
Show/Hide
|
C19H19ClN2O
|
1
|
| 1 |
Kd = 28 nM
|
|
|
|
CP0572093
|
13-chloro-2-piperidin-4-ylidene-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-10-ol
Show/Hide
|
C19H19ClN2O
|
1
|
| 1 |
Kd = 48 nM
|
|
|
|
CP0530670
|
ethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)-2,6-dihydroxypiperidine-1-carboxylate
Show/Hide
|
C22H23ClN2O4
|
1
|
| 1 |
Kd = 51 nM
|
|
|
|
CP0068895
|
ethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
Show/Hide
|
C22H23ClN2O2
|
2
|
| 1 |
Kd = 190 nM
|
|
|
| 2 |
Ki = 37 nM
|
|
|
|
CP0504706
|
ethyl 4-[13-chloro-7-(hydroxymethyl)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-2-ylidene]piperidine-1-carboxylate
Show/Hide
|
C23H25ClN2O3
|
1
|
| 1 |
Kd = 199 nM
|
|
|
|
CP0576008
|
ethyl 4-(4-azatricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,11,13-hexaen-2-ylidene)piperidine-1-carboxylate
Show/Hide
|
C22H24N2O2
|
1
|
| 1 |
Kd = 206 nM
|
|
|
|
CP0530671
|
ethyl 4-(13-chloro-9-fluoro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
Show/Hide
|
C22H22ClFN2O2
|
1
|
| 1 |
Kd = 227 nM
|
|
|
|
CP0540148
|
ethyl 4-(13-chloro-10-hydroxy-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
Show/Hide
|
C22H23ClN2O3
|
1
|
| 1 |
Kd = 257 nM
|
|
|
|
CP0557019
|
ethyl 4-[13-chloro-7-(difluoromethyl)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-2-ylidene]piperidine-1-carboxylate
Show/Hide
|
C23H23ClF2N2O2
|
1
|
| 1 |
Kd = 271 nM
|
|
|
|
CP0574986
|
ethyl (4E)-4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)-3-hydroxypiperidine-1-carboxylate
Show/Hide
|
C22H23ClN2O3
|
1
|
| 1 |
Kd = 423 nM
|
|
|
|
CP0530669
|
ethyl 4-(13-chloro-9-hydroxy-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
Show/Hide
|
C22H23ClN2O3
|
1
|
| 1 |
Kd = 454 nM
|
|
|
|
CP0540150
|
ethyl (4Z)-4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)-2,3-dihydropyridine-1-carboxylate
Show/Hide
|
C22H21ClN2O2
|
1
|
| 1 |
Kd = 454 nM
|
|
|
|
CP0516600
|
ethyl 4-(13-chloro-4-methyl-4-azoniatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
Show/Hide
|
C23H26ClN2O2+
|
1
|
| 1 |
Kd > 1000 nM
|
|
|
|
CP0532147
|
ethyl 13-chloro-5'-oxospiro[4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene-2,4'-azepane]-1'-carboxylate
Show/Hide
|
C22H23ClN2O3
|
1
|
| 1 |
Kd > 1000 nM
|
|
|
|
CP0535281
|
ethyl 4-(13-chloro-6-hydroxy-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
Show/Hide
|
C22H23ClN2O3
|
1
|
| 1 |
Kd > 1000 nM
|
|
|
|
CP0540149
|
ethyl (4Z)-4-(13-chloro-6-hydroxy-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)-2,3-dihydropyridine-1-carboxylate
Show/Hide
|
C22H21ClN2O3
|
1
|
| 1 |
Kd > 1000 nM
|
|
|
|
CP0540151
|
ethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-2-ylidene)piperidine-1-carboxylate
Show/Hide
|
C22H21ClN2O2
|
1
|
| 1 |
Kd > 1000 nM
|
|
|
|
CP0548669
|
ethyl 4-[13-chloro-5-(difluoromethyl)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene]piperidine-1-carboxylate
Show/Hide
|
C23H23ClF2N2O2
|
1
|
| 1 |
Kd > 1000 nM
|
|
|
|
CP0553695
|
ethyl (4E)-4-(13-chloro-6-hydroxy-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)-2,3-dihydropyridine-1-carboxylate
Show/Hide
|
C22H21ClN2O3
|
1
|
| 1 |
Kd > 1000 nM
|
|
|
|
CP0557018
|
ethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)-3,5-dihydroxypiperidine-1-carboxylate
Show/Hide
|
C22H23ClN2O4
|
1
|
| 1 |
Kd > 1000 nM
|
|
|
|
CP0557020
|
CHEMBL4648718
Show/Hide
|
C22H23ClN2O4
|
1
|
| 1 |
Kd > 1000 nM
|
|
|
|
CP0558415
|
ethyl (4E)-4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)-2,3-dihydropyridine-1-carboxylate
Show/Hide
|
C22H21ClN2O2
|
1
|
| 1 |
Kd > 1000 nM
|
|
|
|
CP0572094
|
ethyl (4E)-4-(13-chloro-9-hydroxy-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)-2,3-dihydropyridine-1-carboxylate
Show/Hide
|
C22H21ClN2O3
|
1
|
| 1 |
Kd > 1000 nM
|
|
|
|
CP0575991
|
CHEMBL4634809
Show/Hide
|
C22H23ClN2O3
|
1
|
| 1 |
Kd > 1000 nM
|
|
|
|
CP0576007
|
ethyl 4-(13-chloro-4-oxido-4-azoniatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
Show/Hide
|
C22H23ClN2O3
|
1
|
| 1 |
Kd > 1000 nM
|
|
|
|
CP0462897
|
4-[(4-methoxyphenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C22H25N3O2
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0040455
|
(Z)-2-butenedioate;10-(1-methyl-4-piperidinylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one
Show/Hide
|
C19H19NOS
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
|
CP0377781
|
4-[(4-hydroxyphenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C21H23N3O2
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
|
CP0080536
|
1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)-4-methyl-piperazine;maleate
Show/Hide
|
C19H21ClN2S
|
1
|
| 1 |
Ki = 0.19 nM
|
|
|
|
CP0520928
|
4-[(4-methylphenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C22H25N3O
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
|
CP0466028
|
4-[(3,4-difluorophenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C21H21F2N3O
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0513253
|
4-[(4-chlorophenyl)methyl]-2-[2-(dimethylamino)ethyl]phthalazin-1-one
Show/Hide
|
C19H20ClN3O
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0372186
|
4-[(4-fluorophenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C21H22FN3O
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0513990
|
4-[(4-chlorophenyl)methyl]-2-[[(2S)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C21H22ClN3O
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0513989
|
4-[(3-fluorophenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C21H22FN3O
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0046703
|
1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one
Show/Hide
|
C24H26ClFN4O
|
1
|
| 1 |
Ki = 0.51 nM
|
|
|
|
CP0100763
|
4-[(4-chlorophenyl)methyl]-2-[[(2R)-1-(2-methoxyethyl)pyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C23H26ClN3O2
|
1
|
| 1 |
Ki = 0.5129 nM
|
|
|
|
CP0056746
|
8-[(4-chlorophenyl)methyl]-6-[[(2R)-1-(2-methoxyethyl)pyrrolidin-2-yl]methyl]pyrido[2,3-d]pyridazin-5-one
Show/Hide
|
C22H25ClN4O2
|
1
|
| 1 |
Ki = 0.537 nM
|
|
|
|
CP0050128
|
N,N-dimethyl-1-[(2S,4R,6R)-3-oxatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
Show/Hide
|
C20H23NO
|
1
|
| 1 |
Ki = 0.54 nM
|
|
|
|
CP0422236
|
N,N-dimethyl-1-[(2S,4S,6R)-3-oxatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
Show/Hide
|
C20H23NO
|
1
|
| 1 |
Ki = 0.63 nM
|
|
|
|
CP0374581
|
4-piperazin-1-yl-10H-imidazo[1,2-b][2]benzazepine
Show/Hide
|
C16H18N4
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0148522
|
6-[[(2R)-1-butylpyrrolidin-2-yl]methyl]-8-[(4-chlorophenyl)methyl]pyrido[2,3-d]pyridazin-5-one
Show/Hide
|
C23H27ClN4O
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0530334
|
N,N-dimethyl-1-[(4S,6R)-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
Show/Hide
|
C19H22N2O
|
1
|
| 1 |
Ki = 0.64 nM
|
|
|
|
CP0478245
|
N,N-dimethyl-1-[(2S,6R)-3-oxatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
Show/Hide
|
C20H23NO
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0372193
|
4-[(3-methylphenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C22H25N3O
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0372187
|
4-[(4-chlorophenyl)methyl]-2-(1-methylpiperidin-4-yl)phthalazin-1-one
Show/Hide
|
C21H22ClN3O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0060491
|
10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene
Show/Hide
|
C20H23N
|
1
|
| 1 |
Ki = 1.12 nM
|
|
|
|
CP0461357
|
1-Methyl-4-[(3aR,12bS)-1-(2,3,3a,12b-tetrahydro-1-oxa-8-thia-dibenzo[e,h]azulen-2-yl)methyl]-piperazine
Show/Hide
|
C22H26N2OS
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0500011
|
2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]-4-pentylphthalazin-1-one
Show/Hide
|
C19H27N3O
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0520920
|
4-[(3-chlorophenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C21H22ClN3O
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0058675
|
N-methyl-3-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyl)propan-1-amine
Show/Hide
|
C20H23N
|
1
|
| 1 |
Ki = 1.67 nM
|
|
|
|
CP0403652
|
(4-Fluoro-phenyl)-{1-[(3aR,12bS)-1-(3,3a,8,12b-tetrahydro-2H-1-oxa-dibenzo[e,h]azulen-2-yl)methyl]-piperidin-4-yl}-methanone
Show/Hide
|
C30H30FNO2
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0372191
|
4-[(3-methoxyphenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C22H25N3O2
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0383041
|
4-[(3aR,12bS)-1-(3,3a,8,12b-Tetrahydro-2H-1-oxa-dibenzo[e,h]azulen-2-yl)methyl]-morpholine
Show/Hide
|
C22H25NO2
|
1
|
| 1 |
Ki = 2.36 nM
|
|
|
|
CP0025667
|
2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone
Show/Hide
|
C18H19ClN4
|
1
|
| 1 |
Ki = 2.38 nM
|
|
|
|
CP0240469
|
(S)-N-((11-(4-methylpiperazin-1-yl)-10,11-dihydrodibenzo[b,f]thiepin-2-yl)methyl)acetamide
Show/Hide
|
C22H27N3OS
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0377782
|
4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-3-yl)phthalazin-1-one
Show/Hide
|
C22H24ClN3O
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0401076
|
1-Methyl-4-[(3aR,12bS)-1-(3,3a,8,12b-tetrahydro-2H-1-oxa-dibenzo[e,h]azulen-2-yl)methyl]-piperazine
Show/Hide
|
C23H28N2O
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0453367
|
N-methyl-1-[(2R,4S,6S)-3-oxatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
Show/Hide
|
C19H21NO
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0205856
|
(R)-N-((11-(4-methylpiperazin-1-yl)-10,11-dihydrodibenzo[b,f]thiepin-2-yl)methyl)acetamide
Show/Hide
|
C22H27N3OS
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0457342
|
2-{4-[(3aR,12bS)-1-(3,3a,8,12b-Tetrahydro-2H-1-oxa-dibenzo[e,h]azulen-2-yl)methyl]-piperazin-1-yl}-ethanol
Show/Hide
|
C24H30N2O2
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0420430
|
N,N-dimethyl-1-[(2R,4S,6S)-3-oxatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
Show/Hide
|
C20H23NO
|
1
|
| 1 |
Ki = 3.74 nM
|
|
|
|
CP0134204
|
(3Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine
Show/Hide
|
C18H18ClNS
|
1
|
| 1 |
Ki = 3.75 nM
|
|
|
|
CP0472908
|
(3S)-N,N-dimethylspiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-amine
Show/Hide
|
C21H25N
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0033479
|
(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine
Show/Hide
|
C17H19ClN2S
|
1
|
| 1 |
Ki = 4.25 nM
|
|
|
|
CP0454651
|
N,N-dimethyl-1-[(2S,6R)-3-oxa-13-thiatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
Show/Hide
|
C19H21NOS
|
1
|
| 1 |
Ki = 4.3 nM
|
|
|
|
CP0167141
|
(R)-N-((11-(4-methylpiperazin-1-yl)-10,11-dihydrodibenzo[b,f]thiepin-2-yl)methyl)isobutyramide
Show/Hide
|
C24H31N3OS
|
1
|
| 1 |
Ki = 4.5 nM
|
|
|
|
CP0260914
|
(S)-N-((11-(4-methylpiperazin-1-yl)-10,11-dihydrodibenzo[b,f]thiepin-2-yl)methyl)isobutyramide
Show/Hide
|
C24H31N3OS
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0504276
|
4-[(4-ethoxyphenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0438192
|
N,N-dimethyl-1-[(2S,6R)-13-methyl-3-oxa-13-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0279245
|
1-((1S)-5',11'-Dihydrospiro[cyclopentane-1,10'-dibenzo[a,d]-cyclohepten]-3-yl)-3-azetidinecarboxylic Acid
Show/Hide
|
C23H25NO2
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0500010
|
4-[(4-chlorophenyl)methyl]-2-[(1-methylpyrrolidin-3-yl)methyl]phthalazin-1-one
Show/Hide
|
C21H22ClN3O
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0448928
|
N-methyl-1-[(2S,6R)-3-oxatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
Show/Hide
|
C19H21NO
|
1
|
| 1 |
Ki = 9.3 nM
|
|
|
|
CP0438554
|
1-[(2S,6R)-3,13-dioxatetracyclo[13.4.0.02,6.07,12]nonadeca-1(19),7,9,11,15,17-hexaen-4-yl]-N,N-dimethylmethanamine
Show/Hide
|
C20H23NO2
|
1
|
| 1 |
Ki = 9.6 nM
|
|
|
|
CP0279247
|
3-[[(3S)-spiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-yl]amino]propanoic acid
Show/Hide
|
C22H25NO2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0494366
|
4-[(4-chlorophenyl)methyl]-2-[3-(dimethylamino)propyl]phthalazin-1-one
Show/Hide
|
C20H22ClN3O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0499519
|
1-Methyl-4-piperidin-4-ylidene-1,4-dihydro-1,5,7a-triaza-cyclopenta[f]azulen-9-one; oxalic acid
Show/Hide
|
C16H18N4O
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0147752
|
1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine
Show/Hide
|
C19H21ClN2S
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0493859
|
3-methyl-1-[(3S)-spiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-yl]pyrrolidine-3-carboxylic acid
Show/Hide
|
C25H29NO2
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0450308
|
3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinolin-2-yl]propanoic acid
Show/Hide
|
C33H44N4O3
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0454625
|
1-[(2S,6R)-3,13-dioxatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]-N,N-dimethylmethanamine
Show/Hide
|
C19H21NO2
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0112004
|
1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine
Show/Hide
|
C19H21ClN2S
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0497802
|
1-[(3S)-spiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-yl]pyrrolidine-3-carboxylic acid
Show/Hide
|
C24H27NO2
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0497808
|
methyl 1-[(3S)-spiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-yl]-3,6-dihydro-2H-pyridine-5-carboxylate
Show/Hide
|
C26H29NO2
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0372189
|
2-[1-[3-[4-[3-(azepan-1-yl)propoxy]phenyl]propyl]azepan-4-yl]-4-[(4-chlorophenyl)methyl]phthalazin-1-one
Show/Hide
|
C39H49ClN4O2
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0460645
|
2-[1-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]azepan-4-yl]-4-[(4-chlorophenyl)methyl]phthalazin-1-one
Show/Hide
|
C38H47ClN4O2
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0497408
|
[1-[(4-methylphenyl)methyl]piperidin-4-yl]-diphenylmethanol
Show/Hide
|
C26H29NO
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0916420
|
VAPITADINE DIHYDROCHLORIDE
Show/Hide
|
C17H22Cl2N4O
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0487906
|
3-[4-(10H-imidazo[1,2-b][2]benzazepin-4-yl)-2,6-dimethylpiperazin-1-yl]propanoic acid
Show/Hide
|
C21H26N4O2
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0475730
|
(3R)-1-[(3S)-spiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-yl]piperidine-3-carboxylic acid
Show/Hide
|
C25H29NO2
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0494367
|
2-[1-[4-[4-[3-(azepan-1-yl)propoxy]phenyl]butyl]azepan-4-yl]-4-[(4-chlorophenyl)methyl]phthalazin-1-one
Show/Hide
|
C40H51ClN4O2
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0455172
|
methyl 4-[4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]benzoate
Show/Hide
|
C30H35NO3
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0461004
|
1-[(2S,6R)-3,14-dioxatetracyclo[13.4.0.02,6.07,12]nonadeca-1(19),7,9,11,15,17-hexaen-4-yl]-N,N-dimethylmethanamine
Show/Hide
|
C20H23NO2
|
1
|
| 1 |
Ki = 20.6 nM
|
|
|
|
CP0514167
|
1-Methyl-4-piperidin-4-ylidene-1,4,8,9-tetrahydro-1,5,7a-triaza-cyclopenta[f]azulene
Show/Hide
|
C16H20N4
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0470855
|
3-[4-(10H-imidazo[1,2-b][2]benzazepin-4-yl)piperazin-1-yl]-2,2-dimethylpropanoic acid
Show/Hide
|
C21H26N4O2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0279246
|
3-[[(3R)-spiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-yl]amino]propanoic acid
Show/Hide
|
C22H25NO2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0524075
|
2-(1-spiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-ylpiperidin-4-yl)acetic acid
Show/Hide
|
C26H31NO2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0372190
|
2-[[(2S)-1-[4-[4-[3-(azepan-1-yl)propoxy]phenyl]butyl]pyrrolidin-2-yl]methyl]-4-[(4-chlorophenyl)methyl]phthalazin-1-one
Show/Hide
|
C39H49ClN4O2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0448518
|
N,N-dimethyl-1-[(2S,6S)-3-oxatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
Show/Hide
|
C20H23NO
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0025032
|
2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid
Show/Hide
|
C32H39NO4
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0480878
|
4-Phenyl-1-[(3aR,12bS)-1-(3,3a,8,12b-tetrahydro-2H-1-oxa-dibenzo[e,h]azulen-2-yl)methyl]-piperidine
Show/Hide
|
C29H31NO
|
1
|
| 1 |
Ki = 29.7 nM
|
|
|
|
CP0374584
|
2-[[4-(10H-imidazo[1,2-b][2]benzazepin-4-yl)piperazin-1-yl]methyl]prop-2-enoic acid
Show/Hide
|
C20H22N4O2
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0342216
|
3-((1S)-5',11'-Dihydrospiro[cyclopentane-1,10'-dibenzo[a,d]-cyclohepten]-3-yl)-3-azabicyclo[3.1.0]hexane-1-carboxylic Acid
Show/Hide
|
C25H27NO2
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0379547
|
2-[1-[(3S)-spiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-yl]pyrrolidin-3-yl]acetic acid
Show/Hide
|
C25H29NO2
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0479055
|
2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]-4-(2-phenylethyl)phthalazin-1-one
Show/Hide
|
C22H25N3O
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0463465
|
1-[(2S,6S)-3,13-dioxatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]-N,N-dimethylmethanamine
Show/Hide
|
C19H21NO2
|
1
|
| 1 |
Ki = 32.6 nM
|
|
|
|
CP0480039
|
1-[4-(4-methylphenyl)butyl]-alpha,alpha-diphenyl-4-piperdine-methanol
Show/Hide
|
C29H35NO
|
1
|
| 1 |
Ki = 39 nM
|
|
|
|
CP0374587
|
3-[4-(1,2-dimethyl-10H-imidazo[1,2-b][2]benzazepin-4-yl)piperazin-1-yl]-2,2-dimethylpropanoic acid
Show/Hide
|
C23H30N4O2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0374588
|
3-[4-(1-chloro-10H-imidazo[1,2-b][2]benzazepin-4-yl)piperazin-1-yl]-2,2-dimethylpropanoic acid
Show/Hide
|
C21H25ClN4O2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0374589
|
3-[4-(2-fluoro-10H-imidazo[1,2-b][2]benzazepin-4-yl)piperazin-1-yl]-2,2-dimethylpropanoic acid
Show/Hide
|
C21H25FN4O2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0493850
|
1-spiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-yl-3,6-dihydro-2H-pyridine-4-carboxylic acid
Show/Hide
|
C25H27NO2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0493851
|
1-(6'-fluorospiro[cyclopentane-3,10'-tricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,11,13-hexaene]-1-yl)-3,6-dihydro-2H-pyridine-5-carboxylic acid
Show/Hide
|
C25H26FNO2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0493856
|
1-((1S)-5',11'-Dihydrospiro[cyclopentane-1,10'-dibenzo[a,d]-cyclohepten]-3-yl)-4-fluoro-4-piperidinecarboxylic Acid
Show/Hide
|
C25H28FNO2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0511822
|
(1S,5R)-3-spiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-yl-3-azabicyclo[3.1.0]hexane-6-carboxylic acid
Show/Hide
|
C25H27NO2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0437972
|
2-[2-[4-[4-[3-(azepan-1-yl)propoxy]phenyl]butylamino]ethyl]-4-[(4-chlorophenyl)methyl]phthalazin-1-one
Show/Hide
|
C36H45ClN4O2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0507753
|
2-[2-[4-[4-[3-(azepan-1-yl)propoxy]phenyl]butyl-methylamino]ethyl]-4-[(4-chlorophenyl)methyl]phthalazin-1-one
Show/Hide
|
C37H47ClN4O2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0512424
|
3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinolin-3-yl]propanoic acid
Show/Hide
|
C33H44N4O3
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0047409
|
2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride
Show/Hide
|
C22H26F3N3OS
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0437726
|
N-methyl-N-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]-3-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyl)propan-1-amine
Show/Hide
|
C35H44N2O
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0033565
|
(+/-)1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol
Show/Hide
|
C32H41NO2
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0438782
|
4-Phenyl-1-[(3aR,12bS)-1-(2,3,3a,12b-tetrahydro-1-oxa-8-thia-dibenzo[e,h]azulen-2-yl)methyl]-piperidine
Show/Hide
|
C28H29NOS
|
1
|
| 1 |
Ki = 47.1 nM
|
|
|
|
CP0908149
|
LEVOCETIRIZINE DIHYDROCHLORIDE
Show/Hide
|
C21H27Cl3N2O3
|
1
|
| 1 |
Ki = 50 nM
|
|
|
|
CP0374582
|
3-[4-(10H-imidazo[1,2-b][2]benzazepin-4-yl)piperazin-1-yl]propanoic acid
Show/Hide
|
C19H22N4O2
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0374583
|
3-[4-(10H-imidazo[1,2-b][2]benzazepin-4-yl)-1,4-diazepan-1-yl]-2,2-dimethylpropanoic acid
Show/Hide
|
C22H28N4O2
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0477585
|
2,2-dimethyl-3-[4-(2-methyl-10H-imidazo[1,2-b][2]benzazepin-4-yl)piperazin-1-yl]propanoic acid
Show/Hide
|
C22H28N4O2
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0335817
|
1-(11'H-Spiro[cyclopentane-1,10'-dibenzo[b,f]oxepin]-3-yl)-3-azetidinecarboxylic Acid
Show/Hide
|
C22H23NO3
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0340560
|
(-)-1-((1S)-5',11'-Dihydrospiro[cyclopentane-1,10'-dibenzo-[a,d]cyclohepten]-3-yl)-4-piperidinecarboxylic Acid
Show/Hide
|
C25H29NO2
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0379543
|
4-hydroxy-1-spiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-ylpiperidine-4-carboxylic acid
Show/Hide
|
C25H29NO3
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0497804
|
4-methyl-1-spiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-ylpiperidine-4-carboxylic acid
Show/Hide
|
C26H31NO2
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0505534
|
1-spiro[6H-benzo[b][1]benzoxepine-5,3'-cyclopentane]-1'-yl-3,6-dihydro-2H-pyridine-4-carboxylic acid
Show/Hide
|
C24H25NO3
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0372188
|
2-[1-[[4-[3-(azepan-1-yl)propoxy]phenyl]methyl]azepan-4-yl]-4-[(4-chlorophenyl)methyl]phthalazin-1-one
Show/Hide
|
C37H45ClN4O2
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0374129
|
1-[4-(4-methylcyclohexyl)butyl]alpha,alpha-diphenyl-4-piperdinemethanol
Show/Hide
|
C29H41NO
|
1
|
| 1 |
Ki = 61 nM
|
|
|
|
CP0497803
|
4-[(3S)-spiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-yl]morpholine-2-carboxylic acid
Show/Hide
|
C24H27NO3
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0460644
|
4-[(4-chlorophenyl)methyl]-2-[2-(1-methylpyrrolidin-2-yl)ethyl]phthalazin-1-one
Show/Hide
|
C22H24ClN3O
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0396915
|
[1-[2-(4-methylphenyl)ethyl]piperidin-4-yl]-diphenylmethanol
Show/Hide
|
C27H31NO
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0126974
|
N-[[1-(4-fluorophenyl)-3-[1-[2-(2-oxoimidazolidin-1-yl)ethyl]piperidin-4-yl]indol-5-yl]methyl]acetamide
Show/Hide
|
C27H32FN5O2
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0195465
|
1-(2-(4-(5-(aminomethyl)-1-(4-fluorophenyl)-1H-indol-3-yl)piperidin-1-yl)ethyl)imidazolidin-2-one
Show/Hide
|
C25H30FN5O
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0423208
|
N-methyl-N-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine
Show/Hide
|
C34H42N2O
|
1
|
| 1 |
Ki = 79 nM
|
|
|
|
CP0402437
|
3-[4-(2-chloro-10H-imidazo[1,2-b][2]benzazepin-4-yl)piperazin-1-yl]-2,2-dimethylpropanoic acid
Show/Hide
|
C21H25ClN4O2
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0493852
|
1-spiro[6H-benzo[b][1]benzoxepine-5,3'-cyclopentane]-1'-ylpiperidine-4-carboxylic acid
Show/Hide
|
C24H27NO3
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0522154
|
1-(10'-oxospiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-yl)-3,6-dihydro-2H-pyridine-5-carboxylic acid
Show/Hide
|
C25H25NO3
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0460643
|
4-(cyclohexylmethyl)-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C21H29N3O
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0465007
|
8-[4-[3-[4-[3-(azepan-1-yl)propoxy]phenyl]propyl]piperazin-1-yl]quinoline
Show/Hide
|
C31H42N4O
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0406107
|
1-spiro[6H-benzo[b][1]benzoxepine-5,3'-cyclopentane]-1'-yl-3,6-dihydro-2H-pyridine-5-carboxylic acid
Show/Hide
|
C24H25NO3
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0505536
|
4-[(3S)-spiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-yl]piperazine-2-carboxylic acid
Show/Hide
|
C24H28N2O2
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0461541
|
[1-[4-(4-methylphenyl)butyl]piperidin-4-yl]-phenylmethanol
Show/Hide
|
C23H31NO
|
1
|
| 1 |
Ki = 121 nM
|
|
|
|
CP0477603
|
3-[4-(1-methoxy-10H-imidazo[1,2-b][2]benzazepin-4-yl)piperazin-1-yl]-2,2-dimethylpropanoic acid
Show/Hide
|
C22H28N4O3
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0505545
|
(3R)-1-spiro[6H-benzo[b][1]benzoxepine-5,3'-cyclopentane]-1'-ylpiperidine-3-carboxylic acid
Show/Hide
|
C24H27NO3
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0405412
|
[1-[3-(4-methylphenyl)propyl]piperidin-4-yl]-diphenylmethanol
Show/Hide
|
C28H33NO
|
1
|
| 1 |
Ki = 155 nM
|
|
|
|
CP0379562
|
1-[(3R)-spiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-yl]-3,6-dihydro-2H-pyridine-5-carboxylic acid
Show/Hide
|
C25H27NO2
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0454555
|
4-fluoro-1-spiro[6H-benzo[b][1]benzoxepine-5,3'-cyclopentane]-1'-ylpiperidine-4-carboxylic acid
Show/Hide
|
C24H26FNO3
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0502173
|
8-Chloro-11-{4-[4-(3-piperidin-1-yl-propoxy)-benzyl]-piperazin-1-yl}-5H-dibenzo[b,e][1,4]diazepine
Show/Hide
|
C32H38ClN5O
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0472909
|
1-(3-fluoro-5-oxospiro[benzo[b][1]benzothiepine-6,3'-cyclopentane]-1'-yl)piperidine-4-carboxylic acid
Show/Hide
|
C24H24FNO3S
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0497801
|
(3R)-1-(3-chloro-5-oxospiro[benzo[b][1]benzoxepine-6,3'-cyclopentane]-1'-yl)piperidine-3-carboxylic acid
Show/Hide
|
C24H24ClNO4
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0523799
|
2-(1-spiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-ylazetidin-3-ylidene)acetic acid
Show/Hide
|
C24H25NO2
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0469081
|
(E)-3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinolin-2-yl]prop-2-enoic acid
Show/Hide
|
C33H42N4O3
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0415746
|
4-[4-[4-[hydroxy(diphenyl)methyl]-1-piperidinyl]butyl]benzoic acid
Show/Hide
|
C29H33NO3
|
1
|
| 1 |
Ki = 203 nM
|
|
|
|
CP0371973
|
3-(2-chlorophenothiazin-10-yl)-N-methyl-N-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]propan-1-amine
Show/Hide
|
C31H38ClN3OS
|
1
|
| 1 |
Ki = 205 nM
|
|
|
|
CP0450306
|
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-2-carboxylic acid
Show/Hide
|
C31H40N4O3
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0371976
|
(3E)-3-(2-chlorothioxanthen-9-ylidene)-N-methyl-N-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]propan-1-amine
Show/Hide
|
C32H37ClN2OS
|
1
|
| 1 |
Ki = 295 nM
|
|
|
|
CP0497806
|
2-(1-spiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-ylazetidin-3-yl)acetic acid
Show/Hide
|
C24H27NO2
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0437725
|
4-(3-Piperidin-1-yl-propoxy)-benzoic acid 2-{4-[3-(2-trifluoromethyl-phenothiazin-10-yl)-propyl]-piperazin-1-yl}-ethyl ester
Show/Hide
|
C37H45F3N4O3S
|
1
|
| 1 |
Ki = 390 nM
|
|
|
|
CP0507749
|
4-[(4-tert-butylphenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C25H31N3O
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0450307
|
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-3-carboxylic acid
Show/Hide
|
C31H40N4O3
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0470578
|
1-(3-Chloro-phenyl)-4-[(3aR,12bS)-1-(3,3a,8,12b-tetrahydro-2H-1-oxa-dibenzo[e,h]azulen-2-yl)methyl]-piperazine
Show/Hide
|
C28H29ClN2O
|
1
|
| 1 |
Ki = 471 nM
|
|
|
|
CP0228798
|
1-(2-{4-[1-(4-Fluoro-phenyl)-5-(2-methyl-2H-tetrazol-5-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one
Show/Hide
|
C26H29FN8O
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0371972
|
N-methyl-2-[4-(3-piperidin-1-ylpropoxy)phenyl]-N-[3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propyl]acetamide
Show/Hide
|
C35H42N2O2
|
1
|
| 1 |
Ki = 559 nM
|
|
|
|
CP0437970
|
methyl 4-[[3-[[(2R)-1-methylpyrrolidin-2-yl]methyl]-4-oxophthalazin-1-yl]methyl]benzoate
Show/Hide
|
C23H25N3O3
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0348354
|
diphenyl(piperidin-4-yl)methanol
Show/Hide
|
C18H21NO
|
1
|
| 1 |
Ki = 659 nM
|
|
|
|
CP0491777
|
N-methyl-4-(3-piperidin-1-ylpropoxy)-N-[3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propyl]benzamide
Show/Hide
|
C34H40N2O2
|
1
|
| 1 |
Ki = 686 nM
|
|
|
|
CP0379554
|
3-fluoro-1-[(3S)-spiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-yl]piperidine-3-carboxylic acid
Show/Hide
|
C25H28FNO2
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0075436
|
(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol
Show/Hide
|
C22H28FNO3
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0406094
|
1-(3-chloro-5-oxospiro[benzo[b][1]benzoxepine-6,3'-cyclopentane]-1'-yl)piperidine-4-carboxylic acid
Show/Hide
|
C24H24ClNO4
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0271224
|
3-(cyclopropylmethyl)-7-phenylmethoxy-1,2,4,5-tetrahydro-3-benzazepine
Show/Hide
|
C21H25NO
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0407360
|
3-phenyl-7-(3-piperidin-1-ylpropoxy)-1,2,4,5-tetrahydro-3-benzazepine
Show/Hide
|
C24H32N2O
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0468326
|
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-5-carbonitrile
Show/Hide
|
C31H39N5O
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0119048
|
1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine
Show/Hide
|
C17H26ClNO
|
1
|
| 1 |
Ki = 1148.15 nM
|
|
|
|
CP0890879
|
4-benzoyl-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one hydrochloride
Show/Hide
|
C25H32ClN3O3
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0407304
|
7-(3-piperidin-1-ylpropoxy)-2,3,4,5-tetrahydro-1H-3-benzazepine
Show/Hide
|
C18H28N2O
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0126860
|
1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,3]triazol-4-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one
Show/Hide
|
C27H30FN7O
|
1
|
| 1 |
Ki = 1500 nM
|
|
|
|
CP0437971
|
4-[(3,4-dimethoxyphenyl)methyl]-2-[[(2R)-1-methylpyrrolidin-2-yl]methyl]phthalazin-1-one
Show/Hide
|
C23H27N3O3
|
1
|
| 1 |
Ki = 1584.89 nM
|
|
|
|
CP0670657
|
4-(2-oxo-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazine-4-carbonyl)benzonitrile hydrochloride
Show/Hide
|
C26H31ClN4O3
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0845127
|
4-(2,4-difluorobenzoyl)-1-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one
Show/Hide
|
C24H27F2N3O3
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0896098
|
4-(4-methylbenzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one hydrochloride
Show/Hide
|
C26H34ClN3O3
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0915881
|
4-(2,4-difluorobenzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H31F2N3O5
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0918635
|
4-(4-chlorobenzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one hydrochloride
Show/Hide
|
C25H31Cl2N3O3
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0391158
|
3-(cyclopropylmethyl)-7-(3-piperidin-1-ylpropoxy)-1,2,4,5-tetrahydro-3-benzazepine
Show/Hide
|
C22H34N2O
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0391160
|
3-(oxolan-2-ylmethyl)-7-(3-piperidin-1-ylpropoxy)-1,2,4,5-tetrahydro-3-benzazepine
Show/Hide
|
C23H36N2O2
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0411110
|
5,5-diphenyl-3-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]imidazolidine-2,4-dione
Show/Hide
|
C30H33N3O3
|
1
|
| 1 |
Ki = 2238.72 nM
|
|
|
|
CP0854415
|
1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-4-(4-fluorobenzoyl)piperazin-2-one hydrochloride
Show/Hide
|
C26H31ClFN3O3
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0415745
|
1-(4-p-Tolyl-butyl)-piperidine
Show/Hide
|
C16H25N
|
1
|
| 1 |
Ki = 3200 nM
|
|
|
|
CP0461101
|
5,5-diphenyl-3-(3-piperidin-1-ylpropyl)imidazolidine-2,4-dione
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
Ki = 6165.95 nM
|
|
|
|
CP0044460
|
N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide
Show/Hide
|
C15H24N4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0382124
|
3-[5-methyl-4-[4-(3-piperidin-1-ylpropoxy)phenyl]-1,2,4-triazol-3-yl]pyridine
Show/Hide
|
C22H27N5O
|
1
|
| 1 |
Ki = 10471.29 nM
|
|
|
|
CP0442834
|
1-[3-[4-(3,5-dimethyl-1,2,4-triazol-4-yl)phenoxy]propyl]piperidine
Show/Hide
|
C18H26N4O
|
1
|
| 1 |
Ki = 29512.09 nM
|
|
|
|
CP0488555
|
(2S)-2-[[4-(3-piperidin-1-ylpropoxy)phenyl]methylamino]propanamide
Show/Hide
|
C18H29N3O2
|
1
|
| 1 |
Ki = 31622.78 nM
|
|
|
|
CP0092861
|
2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole
Show/Hide
|
C15H20N2S
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0400519
|
4-((1H-Imidazol-4-yl)methyl)-1-(4-methoxyphenyl)piperidine
Show/Hide
|
C16H21N3O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0438775
|
4-((1H-Imidazol-4-yl)methyl)-1-(4-(trifluoromethyl)-phenyl)piperidine
Show/Hide
|
C16H18F3N3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0544075
|
2-amino-4-phenyl-8-(3-piperidin-1-ylpropoxy)indeno[1,2-d]pyrimidin-5-one
Show/Hide
|
C25H26N4O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0544077
|
4-phenyl-8-(3-pyrrolidin-1-ylpropoxy)-5H-indeno[1,2-d]pyrimidin-2-amine
Show/Hide
|
C24H26N4O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0896091
|
4-(4-chlorobenzoyl)-1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C28H34ClN3O5
|
1
|
| 1 |
Ki < 1584.89 nM
|
|
|
|
CP0915880
|
1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-4-(3,5-difluorobenzoyl)piperazin-2-one formic acid
Show/Hide
|
C27H31F2N3O5
|
1
|
| 1 |
Ki < 1584.89 nM
|
|
|
|
CP0520926
|
4-[[3-[[(2R)-1-methylpyrrolidin-2-yl]methyl]-4-oxophthalazin-1-yl]methyl]benzoic acid
Show/Hide
|
C22H23N3O3
|
1
|
| 1 |
Ki > 1584.89 nM
|
|
|
|
CP0495731
|
4-(4-fluoro-benzoyl)-1-[4-(3-piperidin-1-yl-propoxy)-phenyl]-piperazin-2-one formic acid
Show/Hide
|
C25H30FN3O3
|
1
|
| 1 |
Ki < 1995.26 nM
|
|
|
|
CP0681609
|
4-(4-fluoro-benzoyl)-1-[4-(3-piperidin-1-yl-propoxy)-phenyl]-piperazin-2-one formic acid
Show/Hide
|
C26H32FN3O5
|
1
|
| 1 |
Ki < 1995.26 nM
|
|
|
|
CP0845133
|
(S)-4-(1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
|
C27H32N4O5
|
1
|
| 1 |
Ki < 1995.26 nM
|
|
|
|
CP0845134
|
(S)-4-(4-fluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H32FN3O5
|
1
|
| 1 |
Ki < 1995.26 nM
|
|
|
|
CP0854404
|
(S)-4-(2,4-difluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H31F2N3O5
|
1
|
| 1 |
Ki < 1995.26 nM
|
|
|
|
CP0854444
|
(S)-4-(3,5-difluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H31F2N3O5
|
1
|
| 1 |
Ki < 1995.26 nM
|
|
|
|
CP0860701
|
4-(3,5-difluorobenzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H31F2N3O5
|
1
|
| 1 |
Ki < 1995.26 nM
|
|
|
|
CP0860702
|
4-(4-(methylsulfonyl)benzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one
Show/Hide
|
C26H33N3O5S
|
1
|
| 1 |
Ki < 1995.26 nM
|
|
|
|
CP0860703
|
4-(3,5-difluorobenzoyl)-1-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one
Show/Hide
|
C24H27F2N3O3
|
1
|
| 1 |
Ki < 1995.26 nM
|
|
|
|
CP0860704
|
1-(4-(3-(piperidin-1-yl)propoxy)phenyl)-4-pivaloylpiperazin-2-one hydrochloride
Show/Hide
|
C23H36ClN3O3
|
1
|
| 1 |
Ki < 1995.26 nM
|
|
|
|
CP0873040
|
1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-4-(4-methylbenzoyl)piperazin-2-one hydrochloride
Show/Hide
|
C27H34ClN3O3
|
1
|
| 1 |
Ki < 1995.26 nM
|
|
|
|
CP0890876
|
4-(4-chlorobenzoyl)-1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)piperazin-2-one hydrochloride
Show/Hide
|
C26H31Cl2N3O3
|
1
|
| 1 |
Ki < 1995.26 nM
|
|
|
|
CP0890877
|
(R)-4-(4-fluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H32FN3O5
|
1
|
| 1 |
Ki < 1995.26 nM
|
|
|
|
CP0525012
|
3-(cyclopropylmethyl)-7-(2-piperidin-1-ylethoxy)-1,2,4,5-tetrahydro-3-benzazepine
Show/Hide
|
C21H32N2O
|
1
|
| 1 |
Ki > 1995.26 nM
|
|
|
|
CP0681610
|
4-(1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
|
C28H32N4O5
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0748832
|
(R)-4-(2,4-difluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H31F2N3O5
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0845126
|
1-(4-(3-(azepan-1-yl)propoxy)phenyl)-4-(4-fluorobenzoyl)piperazin-2-one formic acid
Show/Hide
|
C27H34FN3O5
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0845128
|
4-(cyclopropanecarbonyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one hydrochloride
Show/Hide
|
C22H32ClN3O3
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0845129
|
4-isonicotinoyl-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C25H32N4O5
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0845130
|
1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)-4-(3,5-difluorobenzoyl)piperazin-2-one formic acid
Show/Hide
|
C28H33F2N3O5
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0845131
|
4-(1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
|
C29H34N4O5
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0845132
|
1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)-4-(4-fluorobenzoyl)piperazin-2-one formic acid
Show/Hide
|
C28H34FN3O5
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0845135
|
1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)-4-(3-(methylsulfonyl)benzoyl)piperazin-2-one formic acid
Show/Hide
|
C29H37N3O7S
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0845136
|
4-(2-oxo-1-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)piperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
|
C26H30N4O5
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0854442
|
1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)-4-(2,4-difluorobenzoyl)piperazin-2-one formic acid
Show/Hide
|
C28H33F2N3O5
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0860700
|
(R)-4-(1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
|
C27H32N4O5
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0872588
|
4-(4-(azetidine-1-carbonyl)benzoyl)-1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C31H38N4O6
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0890878
|
4-(1-(4-(3-(azepan-1-yl)propoxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
|
C28H34N4O5
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0896096
|
1-(4-(3-(azepan-1-yl)propoxy)phenyl)-4-(2,4-difluorobenzoyl)piperazin-2-one formic acid
Show/Hide
|
C27H33F2N3O5
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0900120
|
1-(4-(3-(azepan-1-yl)propoxy)phenyl)-4-(3,5-difluorobenzoyl)piperazin-2-one formic acid
Show/Hide
|
C27H33F2N3O5
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0900122
|
4-(2,4-difluorobenzoyl)-1-(4-(1-isopropylpiperidin-4-yloxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H31F2N3O5
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0902706
|
4-(4-fluorobenzoyl)-1-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C25H30FN3O5
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0904401
|
4-(4-fluorobenzoyl)-1-(4-(1-isopropylpiperidin-4-yloxy)phenyl)piperazin-2-one hydrochloride
Show/Hide
|
C25H31ClFN3O3
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0906031
|
4-(4-(azetidine-1-carbonyl)benzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C30H38N4O6
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0915877
|
4-(3,5-difluorobenzoyl)-1-(4-(1-isopropylpiperidin-4-yloxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H31F2N3O5
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0915879
|
1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)-4-(4-(methylsulfonyl)benzoyl)piperazin-2-one formic acid
Show/Hide
|
C29H37N3O7S
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0915882
|
(R)-4-(3,5-difluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H31F2N3O5
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0916136
|
1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-4-(2,4-difluorobenzoyl)piperazin-2-one formic acid
Show/Hide
|
C27H31F2N3O5
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0918636
|
4-benzoyl-1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)piperazin-2-one hydrochloride
Show/Hide
|
C26H32ClN3O3
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0939742
|
1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-4-(4-(methylsulfonyl)benzoyl)piperazin-2-one formic acid
Show/Hide
|
C28H35N3O7S
|
1
|
| 1 |
Ki < 2511.89 nM
|
|
|
|
CP0099745
|
4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imidazole
Show/Hide
|
C16H18N2O2
|
1
|
| 1 |
Ki > 2511.89 nM
|
|
|
|
CP0391159
|
N-[(3S)-1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]pyrrolidin-3-yl]-1,3-benzodioxole-5-carboxamide
Show/Hide
|
C27H35N3O4
|
1
|
| 1 |
Ki > 2511.89 nM
|
|
|
|
CP0391163
|
7-(1-propan-2-ylpiperidin-4-yl)oxy-2,3,4,5-tetrahydro-1H-3-benzazepine
Show/Hide
|
C18H28N2O
|
1
|
| 1 |
Ki > 2511.89 nM
|
|
|
|
CP0461430
|
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-4-carboxylic acid
Show/Hide
|
C31H40N4O3
|
1
|
| 1 |
Ki > 2511.89 nM
|
|
|
|
CP0461431
|
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-6-carboxylic acid
Show/Hide
|
C31H40N4O3
|
1
|
| 1 |
Ki > 2511.89 nM
|
|
|
|
CP0465009
|
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-7-carboxylic acid
Show/Hide
|
C31H40N4O3
|
1
|
| 1 |
Ki > 2511.89 nM
|
|
|
|
CP0845124
|
4-(1-(4-(1-isopropylpiperidin-4-yloxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
|
C27H32N4O5
|
1
|
| 1 |
Ki < 3162.28 nM
|
|
|
|
CP0845125
|
4-(4-chlorobenzoyl)-1-(4-(1-isopropylpiperidin-4-yloxy)phenyl)piperazin-2-one hydrochloride
Show/Hide
|
C25H31Cl2N3O3
|
1
|
| 1 |
Ki < 3162.28 nM
|
|
|
|
CP0896097
|
1-(4-(3-(piperidin-1-yl)propoxy)phenyl)-4-(pyrazolo[1,5-a]pyrimidine-3-carbonyl)piperazin-2-one formic acid
Show/Hide
|
C26H32N6O5
|
1
|
| 1 |
Ki < 3162.28 nM
|
|
|
|
CP0920179
|
4-(3-(methylsulfonyl)benzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C27H35N3O7S
|
1
|
| 1 |
Ki < 3162.28 nM
|
|
|
