Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8-[(4-chlorophenyl)methyl]-6-[[(2R)-1-(2-methoxyethyl)pyrrolidin-2-yl]methyl]pyrido[2,3-d]pyridazin-5-one
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 PubChem ID
CID: 71458205
SID: 163439818
Canonical SMILES
COCCN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2ncccc2c1=O
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Compound Formula C22H25ClN4O2
Compound Structure
Protein Name
 Protein Info 
Histamine H1 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
P35367
Gene Name
HRH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 0.537 nM
   TI
   LI
   LO
   TS