Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-methyl-1-[(3S)-spiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-yl]pyrrolidine-3-carboxylic acid
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 PubChem ID
CID: 49836525
SID: 103912225
Canonical SMILES
CC1(CCN(C1)C1CC[C@@]2(C1)Cc1ccccc1Cc1ccccc21)C(O)=O
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Compound Formula C25H29NO2
Compound Structure
Protein Name
 Protein Info 
Histamine H1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
P35367
Gene Name
HRH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 12.59 nM
   TI
   LI
   LO
   TS