Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(9,17-difluoro-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7(12),8,10,15,17-hexaen-4-yl)-N,N-dimethylmethanamine
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 PubChem ID
CID: 10246054
SID: 15248970
Canonical SMILES
CN(C)CC1CC2N(O1)c1cc(F)ccc1Cc1ccc(F)cc21
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Compound Formula C19H20F2N2O
Compound Structure
Protein Name
 Protein Info 
Histamine H1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
>
Histamine receptor
Uniprot ID
P35367
Gene Name
HRH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 16.98 nM
   TI
   LI
   LO
   TS