Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-((1S)-5',11'-Dihydrospiro[cyclopentane-1,10'-dibenzo[a,d]-cyclohepten]-3-yl)-4-fluoro-4-piperidinecarboxylic Acid
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 PubChem ID
CID: 49836410
SID: 103912101
Canonical SMILES
OC(=O)C1(F)CCN(CC1)C1CC[C@@]2(C1)Cc1ccccc1Cc1ccccc21
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Compound Formula C25H28FNO2
Compound Structure
Protein Name
 Protein Info 
Histamine H1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
P35367
Gene Name
HRH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 39.81 nM
   TI
   LI
   LO
   TS