Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(10'-oxospiro[cyclopentane-3,9'-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaene]-1-yl)-3,6-dihydro-2H-pyridine-5-carboxylic acid
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 PubChem ID
CID: 49836739
SID: 103912453
Canonical SMILES
OC(=O)C1=CCCN(C1)C1CCC2(C1)c1ccccc1Cc1ccccc1C2=O
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Compound Formula C25H25NO3
Compound Structure
Protein Name
 Protein Info 
Histamine H1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
P35367
Gene Name
HRH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 79.43 nM
   TI
   LI
   LO
   TS